메뉴 건너뛰기




Volumn 33, Issue 9, 2013, Pages 935-955

An essential primer for understanding the role of topical hemostats, surgical sealants, and adhesives for maintaining hemostasis

Author keywords

Gelatin; Hemostasis; Pharmacist's role; Pharmacy and therapeutics committee; Sealant; Surgical bleeding; Thrombin; Topical hemostat

Indexed keywords

COLLAGEN; CYANOACRYLIC ACID OCTYL ESTER; FIBRIN GLUE; GELATIN SPONGE; GELFOAM; HEMOSTATIC AGENT; MICROCRYSTALLINE COLLAGEN; OXIDIZED REGENERATED CELLULOSE; SURGICAL GLUE; THROMBIN;

EID: 84885363323     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1002/phar.1291     Document Type: Review
Times cited : (70)

References (107)
  • 1
    • 84856477196 scopus 로고    scopus 로고
    • National Center for Health Statistics National Hospital Discharge Survey 2009. Available from Accessed November 16
    • National Center for Health Statistics. Centers for Disease Control and Prevention. National Hospital Discharge Survey, 2009. Available from http://www.cdc.gov/nchs/fastats/insurg. htm. Accessed November 16, 2012
    • (2012) Centers for Disease Control and Prevention
  • 2
    • 84861117312 scopus 로고    scopus 로고
    • Adverse effects of plasma transfusion
    • Pandey S, Vyas GN. Adverse effects of plasma transfusion. Transfusion 2012;52(suppl 1):65S-79S
    • (2012) Transfusion , vol.52 , Issue.SUPPL. 1
    • Pandey, S.1    Vyas, G.N.2
  • 3
    • 65349166375 scopus 로고    scopus 로고
    • Transfusion-related mortality: The ongoing risks of allogeneic blood transfusion and the available strategies for their prevention
    • Vamvakas EC, Blajchman MA. Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention. Blood 2009;113: 3406-17
    • (2009) Blood , vol.113 , pp. 3406-3417
    • Vamvakas, E.C.1    Blajchman, M.A.2
  • 4
    • 68049117215 scopus 로고    scopus 로고
    • Achieving hemostasis in the surgical field
    • Boucher BA, Traub O. Achieving hemostasis in the surgical field. Pharmacotherapy 2009;29:2S-7S
    • (2009) Pharmacotherapy , vol.29
    • Boucher, B.A.1    Traub, O.2
  • 5
    • 0026705069 scopus 로고
    • Vascular effects of thrombin
    • Glusa E. Vascular effects of thrombin. Semin Thromb Hemost 1992;18:296-304
    • (1992) Semin Thromb Hemost , vol.18 , pp. 296-304
    • Glusa, E.1
  • 8
    • 0023600051 scopus 로고
    • Topical hemostatic agents to reduce bleeding from cancellous bone surfaces: A comparison of Gelfoam paste and bone wax
    • Zirna H, Keating SE, DeVincentis AF. Topical hemostatic agents to reduce bleeding from cancellous bone surfaces: a comparison of Gelfoam paste and bone wax. J Foot Surg 1987;26:496-500
    • (1987) J Foot Surg , vol.26 , pp. 496-500
    • Zirna, H.1    Keating, S.E.2    Devincentis, A.F.3
  • 10
    • 23744502081 scopus 로고
    • Council on pharmacy and chemistry: Absorbable gelatin sponge - New and nonofficial remedies
    • Council on Pharmacy and Chemistry
    • Council on Pharmacy and Chemistry. Council on pharmacy and chemistry: absorbable gelatin sponge - new and nonofficial remedies. JAMA 1947;135:921
    • (1947) JAMA , vol.135 , pp. 921
  • 11
    • 23744460332 scopus 로고
    • Prophylaxis of postmammectomy lymphedema by the use of Gelfoam laminated rolls; A preliminary report, with a review of the theories on the etiology of elephantiasis chirurgica and a summary of previous operations for its control
    • Treves N. Prophylaxis of postmammectomy lymphedema by the use of Gelfoam laminated rolls; a preliminary report, with a review of the theories on the etiology of elephantiasis chirurgica and a summary of previous operations for its control. Cancer 1952;5:73-84
    • (1952) Cancer , vol.5 , pp. 73-84
    • Treves, N.1
  • 12
    • 23744504258 scopus 로고
    • Successful use of gelatin foam sponge in surgical restoration of fertility
    • Rarig HR. Successful use of gelatin foam sponge in surgical restoration of fertility. Am J Obstet Gynecol 1963;86:136
    • (1963) Am J Obstet Gynecol , vol.86 , pp. 136
    • Rarig, H.R.1
  • 15
    • 0033918566 scopus 로고    scopus 로고
    • Controlled clinical trial of a novel hemostatic agent in cardiac surgery
    • The Fusion Matrix Study Group
    • Oz MC, Cosgrove DM 3rd, Badduke BR, et al. Controlled clinical trial of a novel hemostatic agent in cardiac surgery. The Fusion Matrix Study Group. Ann Thorac Surg 2000;69:1376-82
    • (2000) Ann Thorac Surg , vol.69 , pp. 1376-1382
    • Oz, M.C.1    Cosgrove, D.M.2    Badduke, B.R.3
  • 17
    • 84885332657 scopus 로고    scopus 로고
    • April 2 Available from 2004 Accessed November 16
    • FDA. FDA public health notification: paralysis from absorbable hemostatic agent. April 2, 2004. Available from http:// www.fda.gov/MedicalDevices/Safety/ AlertsandNotices/Public- HealthNotifications/ucm062146.htm. Accessed November 16, 2012
    • (2012) FDA Public Health Notification: Paralysis from Absorbable Hemostatic Agent
  • 20
    • 84885368743 scopus 로고    scopus 로고
    • Helistat Absorbable Collagen Hemostatic Sponge, prescribing information
    • Integra LifeSciences Corporation
    • Integra LifeSciences Corporation. Helistat Absorbable Collagen Hemostatic Sponge, prescribing information. Plainsboro, NJ; 2011
    • (2011) Plainsboro, NJ
  • 21
    • 84885357477 scopus 로고    scopus 로고
    • Helitene Absorbable Collagen Hemostatic Agent, prescribing information
    • Integra LifeSciences Corporation
    • Integra LifeSciences Corporation. Helitene Absorbable Collagen Hemostatic Agent, prescribing information. Plainsboro, NJ; 2011
    • (2011) Plainsboro, NJ
  • 22
    • 84885335399 scopus 로고    scopus 로고
    • Instat MCH microfibrillar collagen hemostat
    • Johnson & Johnson Wound Management/Ethicon
    • Johnson & Johnson Wound Management/Ethicon. Instat MCH microfibrillar collagen hemostat, prescribing information. 2010
    • (2010) Prescribing Information
  • 23
    • 0017280058 scopus 로고
    • Ultrastructural aspects of interactions of platelets with microcrystalline collagen
    • Zucker WH, Mason RG. Ultrastructural aspects of interactions of platelets with microcrystalline collagen. Am J Pathol 1976;82:129-42
    • (1976) Am J Pathol , vol.82 , pp. 129-142
    • Zucker, W.H.1    Mason, R.G.2
  • 24
    • 0032933586 scopus 로고    scopus 로고
    • Comparison of two topical collagen-based hemostatic sponges during cardiothoracic procedures
    • Zwischenberger JB, Brunston RL Jr, Swann JR, Conti VR. Comparison of two topical collagen-based hemostatic sponges during cardiothoracic procedures. J Invest Surg 1999;12:101-6
    • (1999) J Invest Surg , vol.12 , pp. 101-106
    • Zwischenberger, J.B.1    Brunston Jr., R.L.2    Swann, J.R.3    Conti, V.R.4
  • 25
    • 84885342078 scopus 로고    scopus 로고
    • Inc. Surgicel Original; Surgicel Nu-Knit; Surgicel Fibrillar; Surgicel SNoW Absorbable Hemostats (oxidized regenerated cellulose), prescribing information
    • Johnson & Johnson Wound Management/Ethicon
    • Johnson & Johnson Wound Management/Ethicon, Inc. Surgicel Original; Surgicel Nu-Knit; Surgicel Fibrillar; Surgicel SNoW Absorbable Hemostats (oxidized regenerated cellulose), prescribing information. Somerville, NJ; 2010
    • (2010) Somerville, NJ
  • 26
    • 0041384194 scopus 로고    scopus 로고
    • A comparison of the haemostatic effect of Vivostat patient-derived fibrin sealant with oxidised cellulose (Surgicel) in multiple surgical procedures
    • . Hanks JB, Kjaergard HK, Hollingsbee DA. A comparison of the haemostatic effect of Vivostat patient-derived fibrin sealant with oxidised cellulose (Surgicel) in multiple surgical procedures. Eur Surg Res 2003;35:439-44
    • (2003) Eur Surg Res , vol.35 , pp. 439-444
    • Hanks, J.B.1    Kjaergard, H.K.2    Hollingsbee, D.A.3
  • 27
    • 0003951066 scopus 로고
    • Absorbable cotton, paper and gauze: (Oxidized cellulose)
    • Frantz VK. Absorbable cotton, paper and gauze: (oxidized cellulose). Ann Surg 1943;118:116-26
    • (1943) Ann Surg , vol.118 , pp. 116-126
    • Frantz, V.K.1
  • 28
    • 0036784078 scopus 로고    scopus 로고
    • Oxidized cellulose (Surgicel) granuloma mimicking a primary ovarian tumor
    • Gao HW, Lin CK, Yu CP, Yu MS, Chen A. Oxidized cellulose (Surgicel) granuloma mimicking a primary ovarian tumor. Int J Gynecol Pathol 2002;21:422-3
    • (2002) Int J Gynecol Pathol , vol.21 , pp. 422-423
    • Gao, H.W.1    Lin, C.K.2    Yu, C.P.3    Yu, M.S.4    Chen, A.5
  • 29
    • 0034834195 scopus 로고    scopus 로고
    • Oxidized cellulose haemostat mimicking a possible recurrence of neuroblastoma
    • Azmy AF. Oxidized cellulose haemostat mimicking a possible recurrence of neuroblastoma. BJU Int 2001;88:295-6
    • (2001) BJU Int , vol.88 , pp. 295-296
    • Azmy, A.F.1
  • 31
    • 0030451920 scopus 로고    scopus 로고
    • Oxidized cellulose (Surgicel) granulomata mimicking tumour recurrence
    • Sandhu GS, Elexpuru-Camiruaga JA, Buckley S. Oxidized cellulose (Surgicel) granulomata mimicking tumour recurrence. Br J Neurosurg 1996;10:617-9
    • (1996) Br J Neurosurg , vol.10 , pp. 617-619
    • Sandhu, G.S.1    Elexpuru-Camiruaga, J.A.2    Buckley, S.3
  • 33
    • 77955710422 scopus 로고    scopus 로고
    • Surgicel granuloma: Unusual cause of "recurrent" mass lesion after laparoscopic nephron-sparing surgery for renal cell carcinoma
    • Agarwal MM, Mandal AK, Agarwal S, et al. Surgicel granuloma: unusual cause of "recurrent" mass lesion after laparoscopic nephron-sparing surgery for renal cell carcinoma. Urology 2010;76:334-5
    • (2010) Urology , vol.76 , pp. 334-335
    • Agarwal, M.M.1    Mandal, A.K.2    Agarwal, S.3
  • 35
    • 0036126278 scopus 로고    scopus 로고
    • Intraspinal oxidised cellulose (Surgicel) causing delayed paraplegia after thoracotomy - A report of three cases
    • Brodbelt AR, Miles JB, Foy PM, Broome JC. Intraspinal oxidised cellulose (Surgicel) causing delayed paraplegia after thoracotomy - a report of three cases. Ann R Coll Surg Engl 2002;84:97-9
    • (2002) Ann R Coll Surg Engl , vol.84 , pp. 97-99
    • Brodbelt, A.R.1    Miles, J.B.2    Foy, P.M.3    Broome, J.C.4
  • 38
    • 77955878441 scopus 로고    scopus 로고
    • State-of-the-art review: Hemostats, sealants, and adhesives II: Update as well as how and when to use the components of the surgical toolbox
    • Spotnitz WD, Burks S. State-of-the-art review: hemostats, sealants, and adhesives II: update as well as how and when to use the components of the surgical toolbox. Clin Appl Thromb Hemost 2010;16:497-514
    • (2010) Clin Appl Thromb Hemost , vol.16 , pp. 497-514
    • Spotnitz, W.D.1    Burks, S.2
  • 39
    • 84868301417 scopus 로고    scopus 로고
    • Hemostats, sealants, and adhesives III: A new update as well as cost and regulatory considerations for components of the surgical toolbox
    • Spotnitz WD, Burks S. Hemostats, sealants, and adhesives III: a new update as well as cost and regulatory considerations for components of the surgical toolbox. Transfusion 2012;52:2243-55
    • (2012) Transfusion , vol.52 , pp. 2243-2255
    • Spotnitz, W.D.1    Burks, S.2
  • 40
    • 84885363921 scopus 로고    scopus 로고
    • King Pharmaceuticals Inc. Thrombin-JMI (thrombin, topical USP, bovine origin) package insert
    • King Pharmaceuticals Inc. Thrombin-JMI (thrombin, topical USP, bovine origin) package insert. Bristol, TN; 2010
    • (2010) Bristol, TN
  • 41
    • 84885346218 scopus 로고    scopus 로고
    • ZymoGenetics, Inc. Recothrom Thrombin, Topical (recombinant), prescribing information
    • ZymoGenetics, Inc. Recothrom Thrombin, Topical (recombinant), prescribing information. Seattle, WA; 2009
    • (2009) Seattle, WA
  • 42
    • 67749086025 scopus 로고    scopus 로고
    • Recent developments in topical thrombins
    • Kessler CM, Ortel TL. Recent developments in topical thrombins. Thromb Haemost 2009;102:15-24
    • (2009) Thromb Haemost , vol.102 , pp. 15-24
    • Kessler, C.M.1    Ortel, T.L.2
  • 43
    • 33646484957 scopus 로고    scopus 로고
    • The clinical use and immunologic impact of thrombin in surgery
    • Lawson JH. The clinical use and immunologic impact of thrombin in surgery. Semin Thromb Hemost 2006;32(suppl 1):98-110
    • (2006) Semin Thromb Hemost , vol.32 , Issue.SUPPL. 1 , pp. 98-110
    • Lawson, J.H.1
  • 44
    • 41149096038 scopus 로고    scopus 로고
    • Phase 3, randomized, double-blind study of plasma-derived human thrombin versus bovine thrombin in achieving hemostasis in patients undergoing surgery
    • Doria C, Fischer CP, Wood CG, Li PM, Marra S, Hart J. Phase 3, randomized, double-blind study of plasma-derived human thrombin versus bovine thrombin in achieving hemostasis in patients undergoing surgery. Curr Med Res Opin 2008;24:785-94
    • (2008) Curr Med Res Opin , vol.24 , pp. 785-794
    • Doria, C.1    Fischer, C.P.2    Wood, C.G.3    Li, P.M.4    Marra, S.5    Hart, J.6
  • 45
    • 34447629499 scopus 로고    scopus 로고
    • A phase 3, randomized, double-blind comparative study of the efficacy and safety of topical recombinant human thrombin and bovine thrombin in surgical hemostasis
    • Chapman WC, Singla N, Genyk Y, et al. A phase 3, randomized, double-blind comparative study of the efficacy and safety of topical recombinant human thrombin and bovine thrombin in surgical hemostasis. J Am Coll Surg 2007;205:256-65
    • (2007) J Am Coll Surg , vol.205 , pp. 256-265
    • Chapman, W.C.1    Singla, N.2    Genyk, Y.3
  • 46
    • 84885369162 scopus 로고    scopus 로고
    • Danger of giving topical thrombin intravascularly. ISMP Nurse Advise-ERR 2008;6. Available at
    • Danger of giving topical thrombin intravascularly. ISMP Nurse Advise-ERR 2008;6. Available at www.ismp.org/newsletters/nursing/articles/2008-2003-2001. asp
  • 49
    • 70449728019 scopus 로고    scopus 로고
    • Prospective, randomized clinical trial of the FloSeal matrix sealant in cardiac surgery
    • Nasso G, Piancone F, Bonifazi R, et al. Prospective, randomized clinical trial of the FloSeal matrix sealant in cardiac surgery. Ann Thorac Surg 2009;88:1520-6
    • (2009) Ann Thorac Surg , vol.88 , pp. 1520-1526
    • Nasso, G.1    Piancone, F.2    Bonifazi, R.3
  • 50
    • 0037259373 scopus 로고    scopus 로고
    • Improvement of hemostasis in open and laparoscopically performed partial nephrectomy using a gelatin matrix-thrombin tissue sealant (FloSeal)
    • Richter F, Schnorr D, Deger S, et al. Improvement of hemostasis in open and laparoscopically performed partial nephrectomy using a gelatin matrix-thrombin tissue sealant (FloSeal). Urology 2003;61:73-7
    • (2003) Urology , vol.61 , pp. 73-77
    • Richter, F.1    Schnorr, D.2    Deger, S.3
  • 51
    • 15244345974 scopus 로고    scopus 로고
    • Improved hemostasis during laparoscopic partial nephrectomy using gelatin matrix thrombin sealant
    • Gill IS, Ramani AP, Spaliviero M, et al. Improved hemostasis during laparoscopic partial nephrectomy using gelatin matrix thrombin sealant. Urology 2005;65:463-6
    • (2005) Urology , vol.65 , pp. 463-466
    • Gill, I.S.1    Ramani, A.P.2    Spaliviero, M.3
  • 52
    • 0348230723 scopus 로고    scopus 로고
    • Hemostasis in endoscopic sinus surgery using a specific gelatin-thrombin based agent (Flo- Seal)
    • Baumann A, Caversaccio M. Hemostasis in endoscopic sinus surgery using a specific gelatin-thrombin based agent (Flo- Seal). Rhinology 2003;41:244-9
    • (2003) Rhinology , vol.41 , pp. 244-249
    • Baumann, A.1    Caversaccio, M.2
  • 55
    • 84885347510 scopus 로고    scopus 로고
    • Johnson & Johnson Wound Management/Ethicon, Inc. Evicel Fibrin Sealant (Human), Frozen Solutions of BAC2 (fibrinogen) and Thrombin
    • Johnson & Johnson Wound Management/Ethicon, Inc. Evicel Fibrin Sealant (Human), Frozen Solutions of BAC2 (fibrinogen) and Thrombin. Somerville, NJ; 2009
    • (2009) Somerville, NJ
  • 57
    • 84885337392 scopus 로고    scopus 로고
    • Ethicon, Inc. EVARREST Fibrin Sealant Patch [prescribing information]
    • Ethicon, Inc. EVARREST Fibrin Sealant Patch [prescribing information]. Somerville, NJ; 2012
    • (2012) Somerville, NJ
  • 58
    • 0034801567 scopus 로고    scopus 로고
    • Fibrin sealants in surgical practice: An overview
    • Jackson MR. Fibrin sealants in surgical practice: an overview. Am J Surg 2001;182:1S-7S
    • (2001) Am J Surg , vol.182
    • Jackson, M.R.1
  • 59
    • 70349266541 scopus 로고    scopus 로고
    • Clinical use of topical thrombin as a surgical hemostat
    • Lew WK, Weaver FA. Clinical use of topical thrombin as a surgical hemostat. Biologics 2008;2:593-9
    • (2008) Biologics , vol.2 , pp. 593-599
    • Lew, W.K.1    Weaver, F.A.2
  • 60
    • 0024560149 scopus 로고
    • Randomized clinical trial of fibrin sealant in patients undergoing resternotomy or reoperation after cardiac operations
    • Rousou J, Levitsky S, Gonzalez-Lavin L, et al. Randomized clinical trial of fibrin sealant in patients undergoing resternotomy or reoperation after cardiac operations. A multicenter study. J Thorac Cardiovasc Surg 1989;97:194-203
    • (1989) A Multicenter Study. J Thorac Cardiovasc Surg , vol.97 , pp. 194-203
    • Rousou, J.1    Levitsky, S.2    Gonzalez-Lavin, L.3
  • 61
    • 34447537864 scopus 로고    scopus 로고
    • Evaluation of the topical hemostatic efficacy and safety of TISSEEL VH S/D fibrin sealant compared with currently licensed TISSEEL VH in patients undergoing cardiac surgery: A phase 3, randomized, doubleblind clinical study
    • Lowe J, Luber J, Levitsky S, et al. Evaluation of the topical hemostatic efficacy and safety of TISSEEL VH S/D fibrin sealant compared with currently licensed TISSEEL VH in patients undergoing cardiac surgery: a phase 3, randomized, doubleblind clinical study. J Cardiovasc Surg (Torino) 2007;48:323-31
    • (2007) J Cardiovasc Surg (Torino) , vol.48 , pp. 323-331
    • Lowe, J.1    Luber, J.2    Levitsky, S.3
  • 62
    • 7744224346 scopus 로고    scopus 로고
    • Comparison of a new fibrin sealant with standard topical hemostatic agents
    • Schwartz M, Madariaga J, Hirose R, et al. Comparison of a new fibrin sealant with standard topical hemostatic agents. Arch Surg 2004;139:1148-54
    • (2004) Arch Surg , vol.139 , pp. 1148-1154
    • Schwartz, M.1    Madariaga, J.2    Hirose, R.3
  • 63
    • 69849115358 scopus 로고    scopus 로고
    • TachoSil surgical patch versus conventional haemostatic fleece material for control of bleeding in cardiovascular surgery: A randomised controlled trial
    • Maisano F, Kjaergard HK, Bauernschmitt R, et al. TachoSil surgical patch versus conventional haemostatic fleece material for control of bleeding in cardiovascular surgery: a randomised controlled trial. Eur J Cardiothorac Surg 2009;36:708-14
    • (2009) Eur J Cardiothorac Surg , vol.36 , pp. 708-714
    • Maisano, F.1    Kjaergard, H.K.2    Bauernschmitt, R.3
  • 64
    • 84885334421 scopus 로고    scopus 로고
    • US Department of Health and Human Services. Available from Accessed November 16
    • US Department of Health and Human Services. Cryoseal FS System [instructions for use]. Available from http://www.fda. gov/downloads/ BiologicsBloodVaccines/BloodBloodProducts/ ApprovedProducts/ PremarketApprovalsPMAs/ucm093321.pdf. Accessed November 16, 2012
    • (2012) Cryoseal FS System [Instructions for Use]
  • 65
    • 84885338692 scopus 로고    scopus 로고
    • ThermoGenesis Expands European Distribution of CryoSeal Fibrin Sealant (FS) System and Thrombin Processing DeviceTM (TPD) to Czech Republic, Slovakia and Greece [press release]
    • SpecialChem CA; June14
    • SpecialChem. ThermoGenesis Expands European Distribution of CryoSeal Fibrin Sealant (FS) System and Thrombin Processing DeviceTM (TPD) to Czech Republic, Slovakia and Greece [press release]. Rancho Cordova, CA; June 14, 2006
    • (2006) Rancho Cordova
  • 66
    • 84885361513 scopus 로고    scopus 로고
    • Orthovita, Inc. Vitagel Surgical Hemostat [instructions for use]
    • Orthovita, Inc. Vitagel Surgical Hemostat [instructions for use]. Malvern, PA; 2007
    • (2007) Malvern
  • 67
    • 0035070504 scopus 로고    scopus 로고
    • A novel collagen-based composite offers effective hemostasis for multiple surgical indications: Results of a randomized controlled trial
    • CoStasis Multi-Center Collaborative Writing Committee
    • CoStasis Multi-Center Collaborative Writing Committee. A novel collagen-based composite offers effective hemostasis for multiple surgical indications: results of a randomized controlled trial. Surgery 2001;129:445-50
    • (2001) Surgery , vol.129 , pp. 445-450
  • 68
    • 0033801924 scopus 로고    scopus 로고
    • Effective control of hepatic bleeding with a novel collagenbased composite combined with autologous plasma: Results of a randomized controlled trial
    • discussion 1205
    • Chapman WC, Clavien PA, Fung J, Khanna A, Bonham A. Effective control of hepatic bleeding with a novel collagenbased composite combined with autologous plasma: results of a randomized controlled trial. Arch Surg 2000;135:1200-4; discussion 1205
    • (2000) Arch Surg , vol.135 , pp. 1200-1204
    • Chapman, W.C.1    Clavien, P.A.2    Fung, J.3    Khanna, A.4    Bonham, A.5
  • 70
    • 84885369131 scopus 로고    scopus 로고
    • Baxter Healthcare Corp. TachoSil [Absorbable Fibrin Sealant Patch]. Westlake Village, CA; Available from Accessed February 4
    • Baxter Healthcare Corp. TachoSil [Absorbable Fibrin Sealant Patch]. Westlake Village, CA; Available from http://www.ecomm.baxter.com/ecatalog/ browseCatalog.do?lid=10001&hid =10001&cid=10016&key= b2978a88d06e96f413a0a2e2bc3cf5&pid=592063. Accessed February 4, 2013
    • (2013)
  • 74
    • 67650721464 scopus 로고    scopus 로고
    • Elefteriades JA. How I do it: utilization of high-pressure sealants in aortic reconstruction
    • Elefteriades JA. How I do it: utilization of high-pressure sealants in aortic reconstruction. J Cardiothorac Surg 2009;4:27
    • (2009) J Cardiothorac Surg , vol.4 , pp. 27
  • 75
    • 0036192268 scopus 로고    scopus 로고
    • A polymeric sealant inhibits anastomotic suture hole bleeding more rapidly than Gelfoam/thrombin: Results of a randomized controlled trial
    • discussion 332
    • Glickman M, Gheissari A, Money S, Martin J, Ballard JL. A polymeric sealant inhibits anastomotic suture hole bleeding more rapidly than Gelfoam/thrombin: results of a randomized controlled trial. Arch Surg 2002;137:326-31; discussion 332
    • (2002) Arch Surg , vol.137 , pp. 326-331
    • Glickman, M.1    Gheissari, A.2    Money, S.3    Martin, J.4    Ballard, J.L.5
  • 76
    • 33846318589 scopus 로고    scopus 로고
    • Safety and efficacy of a novel polyethylene glycol hydrogel sealant for watertight dural repair
    • Cosgrove GR, Delashaw JB, Grotenhuis JA, et al. Safety and efficacy of a novel polyethylene glycol hydrogel sealant for watertight dural repair. J Neurosurg 2007;106:52-8
    • (2007) J Neurosurg , vol.106 , pp. 52-58
    • Cosgrove, G.R.1    Delashaw, J.B.2    Grotenhuis, J.A.3
  • 77
    • 84868600265 scopus 로고    scopus 로고
    • A multicenter, single-blind, prospective randomized trial to evaluate the safety of a polyethylene glycol hydrogel (DuraSeal Dural Sealant System) as a dural sealant in cranial surgery
    • Osbun JW, Ellenbogen RG, Chesnut RM, et al. A multicenter, single-blind, prospective randomized trial to evaluate the safety of a polyethylene glycol hydrogel (DuraSeal Dural Sealant System) as a dural sealant in cranial surgery. World Neurosurg 2012;78:498-504
    • (2012) World Neurosurg , vol.78 , pp. 498-504
    • Osbun, J.W.1    Ellenbogen, R.G.2    Chesnut, R.M.3
  • 78
    • 80054961673 scopus 로고    scopus 로고
    • Polyethylene glycol hydrogel spinal sealant (DuraSeal Spinal Sealant) as an adjunct to sutured dural repair in the spine: Results of a prospective, multicenter, randomized controlled study
    • Kim KD, Wright NM. Polyethylene glycol hydrogel spinal sealant (DuraSeal Spinal Sealant) as an adjunct to sutured dural repair in the spine: results of a prospective, multicenter, randomized controlled study. Spine (Phila Pa 1976) 2011;36:1906-12
    • (2011) Spine (Phila Pa 1976) , vol.36 , pp. 1906-1912
    • Kim, K.D.1    Wright, N.M.2
  • 79
    • 11144355151 scopus 로고    scopus 로고
    • Prospective randomized study evaluating a biodegradable polymeric sealant for sealing intraoperative air leaks that occur during pulmonary resection
    • Allen MS, Wood DE, Hawkinson RW, et al. Prospective randomized study evaluating a biodegradable polymeric sealant for sealing intraoperative air leaks that occur during pulmonary resection. Ann Thorac Surg 2004;77:1792-801
    • (2004) Ann Thorac Surg , vol.77 , pp. 1792-1801
    • Allen, M.S.1    Wood, D.E.2    Hawkinson, R.W.3
  • 80
    • 0036157551 scopus 로고    scopus 로고
    • Cyanoacrylate tissue adhesives for skin closure in the outpatient setting
    • vi-vii
    • Toriumi DM, Bagal AA. Cyanoacrylate tissue adhesives for skin closure in the outpatient setting. Otolaryngol Clin North Am 2002;35:103-18, vi-vii
    • (2002) Otolaryngol Clin North Am , vol.35 , pp. 103-118
    • Toriumi, D.M.1    Bagal, A.A.2
  • 81
    • 0037325766 scopus 로고    scopus 로고
    • Tissue adhesives for traumatic lacerations: A systematic review of randomized controlled trials
    • Farion KJ, Osmond MH, Hartling L, et al. Tissue adhesives for traumatic lacerations: a systematic review of randomized controlled trials. Acad Emerg Med 2003;10:110-8
    • (2003) Acad Emerg Med , vol.10 , pp. 110-118
    • Farion, K.J.1    Osmond, M.H.2    Hartling, L.3
  • 86
    • 0037231451 scopus 로고    scopus 로고
    • Barrier and antibacterial properties of 2-octyl cyanoacrylate- derived wound treatment films
    • Mertz PM, Davis SC, Cazzaniga AL, Drosou A, Eaglstein WH. Barrier and antibacterial properties of 2-octyl cyanoacrylate- derived wound treatment films. J Cutan Med Surg 2003;7:1-6
    • (2003) J Cutan Med Surg , vol.7 , pp. 1-6
    • Mertz, P.M.1    Davis, S.C.2    Cazzaniga, A.L.3    Drosou, A.4    Eaglstein, W.H.5
  • 87
    • 0037231375 scopus 로고    scopus 로고
    • In-vitro analysis for microbial barrier properties of 2-octyl cyanoacrylatederived wound treatment films
    • Narang U, Mainwaring L, Spath G, Barefoot J. In-vitro analysis for microbial barrier properties of 2-octyl cyanoacrylatederived wound treatment films. J Cutan Med Surg 2003;7:13-9
    • (2003) J Cutan Med Surg , vol.7 , pp. 13-19
    • Narang, U.1    Mainwaring, L.2    Spath, G.3    Barefoot, J.4
  • 88
    • 0036762966 scopus 로고    scopus 로고
    • In vitro assessment of microbial barrier properties of Dermabond topical skin adhesive
    • Bhende S, Rothenburger S, Spangler DJ, Dito M. In vitro assessment of microbial barrier properties of Dermabond topical skin adhesive. Surg Infect (Larchmt) 2002;3:251-7
    • (2002) Surg Infect (Larchmt) , vol.3 , pp. 251-257
    • Bhende, S.1    Rothenburger, S.2    Spangler, D.J.3    Dito, M.4
  • 90
    • 0043167983 scopus 로고    scopus 로고
    • Prospective randomized study of a proteinbased tissue adhesive used as a hemostatic and structural adjunct in cardiac and vascular anastomotic repair procedures
    • Coselli JS, Bavaria JE, Fehrenbacher J, Stowe CL, Macheers SK, Gundry SR. Prospective randomized study of a proteinbased tissue adhesive used as a hemostatic and structural adjunct in cardiac and vascular anastomotic repair procedures. J Am Coll Surg 2003;197:243-52
    • (2003) J Am Coll Surg , vol.197 , pp. 243-252
    • Coselli, J.S.1    Bavaria, J.E.2    Fehrenbacher, J.3    Stowe, C.L.4    Macheers, S.K.5    Gundry, S.R.6
  • 91
    • 33646247879 scopus 로고    scopus 로고
    • Platelet gel and fibrin sealant reduce allogeneic blood transfusions in total knee arthroplasty
    • Everts PA, Devilee RJ, Brown Mahoney C, et al. Platelet gel and fibrin sealant reduce allogeneic blood transfusions in total knee arthroplasty. Acta Anaesthesiol Scand 2006;50:593-9
    • (2006) Acta Anaesthesiol Scand , vol.50 , pp. 593-599
    • Everts, P.A.1    Devilee, R.J.2    Brown Mahoney, C.3
  • 93
    • 46049102220 scopus 로고    scopus 로고
    • ASHP guidelines on the pharmacy and therapeutics committee and the formulary system
    • Tyler LS, Cole SW, May JR, et al. ASHP guidelines on the pharmacy and therapeutics committee and the formulary system. Am J Health Syst Pharm 2008;65:1272-83
    • (2008) Am J Health Syst Pharm , vol.65 , pp. 1272-1283
    • Tyler, L.S.1    Cole, S.W.2    May, J.R.3
  • 94
    • 84885344497 scopus 로고    scopus 로고
    • Joint Commission Medication Management Standards. Available from Accessed January 4
    • Joint Commission Medication Management Standards. Available from http://www.jointcommission.org/standards-information/ npsgs.aspx. Accessed January 4, 2013
    • (2013)
  • 95
    • 84857010499 scopus 로고    scopus 로고
    • Centers for Medicare & Medicaid Services Conditions of Participation Available from Accessed January 4
    • Centers for Medicare & Medicaid Services Conditions of Participation. State Operations Manual. Appendix A - Survey Protocol, Regulations and Interpretive Guidelines for Hospitals. Available from http://www.cms.gov/ Regulations-and-Guidance/ Guidance/Manuals/downloads/som107ap-a-hospitals.pdf. Accessed January 4, 2013
    • (2013) State Operations Manual. Appendix A - Survey Protocol, Regulations and Interpretive Guidelines for Hospitals
  • 96
    • 84868255388 scopus 로고    scopus 로고
    • Managing portsite bleeding during less invasive coronary artery bypass grafting
    • Kiani S, Brecht ML, Lovinger K, Poston RS. Managing portsite bleeding during less invasive coronary artery bypass grafting. Heart Surg Forum 2012;15:E272-6
    • (2012) Heart Surg Forum , vol.15
    • Kiani, S.1    Brecht, M.L.2    Lovinger, K.3    Poston, R.S.4
  • 97
    • 41849147134 scopus 로고    scopus 로고
    • Do the benefits of shorter hospital stay associated with the use of fleece-bound sealing outweigh the cost of the materials?
    • discussion 226
    • Anegg U, Rychlik R, Smolle-Juttner F. Do the benefits of shorter hospital stay associated with the use of fleece-bound sealing outweigh the cost of the materials? Interact Cardiovasc Thorac Surg 2008;7:292-6; discussion 226
    • (2008) Interact Cardiovasc Thorac Surg , vol.7 , pp. 292-296
    • Anegg, U.1    Rychlik, R.2    Smolle-Juttner, F.3
  • 99
    • 33847027593 scopus 로고    scopus 로고
    • Blood collection and transfusion in the United States in 2001
    • Sullivan MT, Cotten R, Read EJ, Wallace EL. Blood collection and transfusion in the United States in 2001. Transfusion 2007;47:385-94
    • (2007) Transfusion , vol.47 , pp. 385-394
    • Sullivan, M.T.1    Cotten, R.2    Read, E.J.3    Wallace, E.L.4
  • 100
    • 0036428924 scopus 로고    scopus 로고
    • Cost, outcome, and functional status in octogenarians and septuagenarians after cardiac surgery
    • Engoren M, Arslanian-Engoren C, Steckel D, Neihardt J, Fenn-Buderer N. Cost, outcome, and functional status in octogenarians and septuagenarians after cardiac surgery. Chest 2002;122:1309-15
    • (2002) Chest , vol.122 , pp. 1309-1315
    • Engoren, M.1    Arslanian-Engoren, C.2    Steckel, D.3    Neihardt, J.4    Fenn-Buderer, N.5
  • 101
    • 34250180239 scopus 로고    scopus 로고
    • The contemporary economics of transfusions
    • Spiess BD, Spence RK, Shader A, eds. Philadelphia, PA: Lippincott Williams & Wilkins
    • Hannon TJ, Gjerde KP. The contemporary economics of transfusions. In: Spiess BD, Spence RK, Shader A, eds. Perioperative transfusion medicine. Philadelphia, PA: Lippincott Williams & Wilkins, 2006. 13-38
    • (2006) Perioperative Transfusion Medicine , pp. 13-38
    • Hannon, T.J.1    Gjerde, K.P.2
  • 103
    • 79957629260 scopus 로고    scopus 로고
    • Impact of bleeding-related complications and/or blood product transfusions on hospital costs in inpatient surgical patients
    • Stokes ME, Ye X, Shah M, et al. Impact of bleeding-related complications and/or blood product transfusions on hospital costs in inpatient surgical patients. BMC Health Serv Res 2011;11:135
    • (2011) BMC Health Serv Res , vol.11 , pp. 135
    • Stokes, M.E.1    Ye, X.2    Shah, M.3
  • 105
    • 0028710676 scopus 로고
    • Blood transfusion and blood conservation: Cost and utilization issues
    • Goodnough LT, Bodner MS, Martin JW. Blood transfusion and blood conservation: cost and utilization issues. Am J Med Qual 1994;9:172-83
    • (1994) Am J Med Qual , vol.9 , pp. 172-183
    • Goodnough, L.T.1    Bodner, M.S.2    Martin, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.