A Phase 3, Randomized, Double-Blind Comparative Study of the Efficacy and Safety of Topical Recombinant Human Thrombin and Bovine Thrombin in Surgical Hemostasis

Journal of the American College of Surgeons

Volumn 205, Issue 2, 2007, Pages 256-265

  Chapman, William C ^a   Singla, Neil ^b   Genyk, Yuri ^c   McNeil, James W ^d   Renkens Jr , Kenneth L ^e   Reynolds, Thomas C ^f   Murphy, Aileen ^f   Weaver, Fred A ^c  

^a WASHINGTON UNIVERSITY   (United States)

^b HUNTINGTON MEMORIAL HOSPITAL   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d Vascular Surgery Associates   (United States)

^e INDIANA SPINE GROUP   (United States)

^f ZYMOGENETICS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; GELATIN SPONGE; RECOMBINANT THROMBIN; THROMBIN; THROMBIN ANTIBODY; UNCLASSIFIED DRUG;

ADULT; AGED; ANEMIA; ANTIGENICITY; ARTERY BYPASS; ARTICLE; BLEEDING; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIALYSIS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; FEVER; HEART DISEASE; HEMOSTASIS; HUMAN; HYPERSENSITIVITY; HYPOKALEMIA; INCIDENCE; INSOMNIA; LABORATORY TEST; LIVER RESECTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; PAIN; PERIPHERAL EDEMA; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SPINE SURGERY; SURGICAL MORTALITY; THROMBOEMBOLISM; VOMITING;

ADMINISTRATION, TOPICAL; ADULT; AGED; AGED, 80 AND OVER; DOUBLE-BLIND METHOD; FEMALE; HEMOSTASIS, SURGICAL; HEMOSTATICS; HUMANS; MALE; MIDDLE AGED; RECOMBINANT PROTEINS; THROMBIN;

EID: 34447629499     PISSN: 10727515     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2007.03.020     Document Type: Article

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