Phase 3, randomized, double-blind study of plasma-derived human thrombin versus bovine thrombin in achieving hemostasis in patients undergoing surgery

Current Medical Research and Opinion

Volumn 24, Issue 3, 2008, Pages 785-794

  Doria, Cataldo ^a,h   Fischer, Craig P ^b,c   Wood, Christopher G ^d   Li, P Mark ^e   Marra, Steven ^f   Hart, James ^g  

^a THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

^b HOUSTON METHODIST HOSPITAL   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e Lehigh Valley Physician Group   (United States)

^f Department of Anesthesiology   (United States)

^g ETHICON INC   (United States)

^h THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Cardiovascular surgical procedures; General surgery; Hemostasis; Human thrombin; Immunogenicity; Neurosurgical procedures; Seroconversion

Indexed keywords

ANTIBODY; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 5A; EVITHROM; GELATIN SPONGE; HEMOSTATIC AGENT; HUMAN THROMBIN; THROMBIN; UNCLASSIFIED DRUG;

ADULT; AGED; APPLICATION SITE REACTION; ARTICLE; BLEEDING; BLOOD DISEASE; BLOOD SAMPLING; BLOOD TRANSFUSION; CLINICAL TRIAL; CONNECTIVE TISSUE DISEASE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG FEVER; ENDOCRINE DISEASE; EPIDURAL HEMATOMA; FEMALE; GASTROINTESTINAL DISEASE; HEART DISEASE; HEMATOMA; HEMOSTASIS; HEPATOBILIARY DISEASE; HUMAN; INFECTION; INFESTATION; KIDNEY DISEASE; LABORATORY TEST; LENGTH OF STAY; LYMPHATIC SYSTEM DISEASE; MAJOR CLINICAL STUDY; MALE; MEDIASTINUM DISEASE; MENTAL DISEASE; METABOLIC DISORDER; MULTICENTER STUDY; MUSCULOSKELETAL DISEASE; NAUSEA; NEUROLOGIC DISEASE; NUTRITIONAL DISORDER; PHASE 3 CLINICAL TRIAL; POSTOPERATIVE PERIOD; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY ARREST; RESPIRATORY TRACT DISEASE; SEROCONVERSION; SKIN DISEASE; SURGICAL PATIENT; THORAX DISEASE; TREATMENT OUTCOME; URINARY TRACT DISEASE; VASCULAR DISEASE; VITAL SIGN; WEAKNESS;

ANIMALS; BLOOD LOSS, SURGICAL; CARDIOVASCULAR SURGICAL PROCEDURES; CATTLE; DOUBLE-BLIND METHOD; FEMALE; HEMOSTASIS, SURGICAL; HEMOSTATICS; HUMANS; INTRAOPERATIVE COMPLICATIONS; LENGTH OF STAY; MALE; MIDDLE AGED; NEUROSURGICAL PROCEDURES; PERIOPERATIVE CARE; POSTOPERATIVE HEMORRHAGE; PROSPECTIVE STUDIES; THROMBIN; THROMBIN TIME;

EID: 41149096038     PISSN: 03007995     EISSN: None     Source Type: Journal    
DOI: 10.1185/030079908X273426     Document Type: Article

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