Formulation and characterization of matrix and triple layer matrix tablets for controlled delivery of Tramadol Hydrochloride

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 5, Issue 4, 2013, Pages 458-464

  Sathish, U ^a   Ahmed Syed, Izhar ^a  

^a SR College of Pharmacy   (India)

Author keywords

Controlled release; Linear drug release; Tramadol hydrochloride; Zero order kinetics

Indexed keywords

ALGAROBA; ETHYL CELLULOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; TALC; TRAMADOL; XANTHAN;

ARTICLE; CALIBRATION; CONTROLLED DRUG RELEASE; DRUG CONTENT; DRUG FORMULATION; DRUG GRANULE; DRUG STABILITY; INFRARED SPECTROSCOPY; KINETICS; PHYSICAL CHEMISTRY; TABLET FORMULATION; TABLET FRIABILITY; TABLET HARDNESS; TABLET MATRIX; TABLET PROPERTY; TABLET THICKNESS; VISCOSITY; WEIGHT VARIATION;

EID: 84885350375     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Colombo P, Conte U, Gazzaniga A, Maggi L, Sangalli M. E, Peppas N. Drug release modulation by physical restrictions of matrix swelling. Int J Pharm. 1990; 63: 43-48.
2. Conte U, Maggi L, Colombo P, La Manna A. Multi-layered hydrophilic matrices as constant release devices. J Control Rel. 1993; 26: 39-47.
3. Yihong Qui, Chidambaram N, Kolette F. Design and evaluation of layered diffusional matrices for zero order sustained-release tablets. J Control Rel. 1998; 51: 123-130.
4. Conte U, Maggi L. Modulation from Geomatrix® multi-layer matrix tablets containing drugs of different solubility. Biomaterials. 1996; 17 (9): 889-896.
5. Yihong Qui and Kolette F. Design of sustained release matrix system for a highly water soluble compound ABT-089. Int J Pharm. 1997; 157: 46-52.
6. Krishnaiah YSR, Karthikeyan S, Gouri VS, Satyanarayana V. Three-layer guar gum matrix tablet formulations for oral controlled delivery of highly soluble trimetazidine dihydrochloride. J Control Rel. 2002; 81: 45-56.
7. Yeole PG, Galgatte UC, Babla IB, Nakhat PD. Design and evaluation of Xanthan gum-based sustained release Matrix tablets of Diclofenac sodium. Indian J. Pharmaceutical Sci. 2006; 68: 185-189.
8. Tobyn MJ, Stani forth JN, Baichwal AR and Mc Call TW. Prediction of physical properties of a novel polysaccharide controlled release system. Int J Pharm. 1996; 128: 113-22.
9. Talukdar MM, Mooter VD, Augustijns P, Maga TT, Verbeke N, Kinget R. In-vitro evaluation of xanthan gum as potential excipients for oral controlled release matrix tablet formulation. Int J Pharm. 1998; 169: 105-13.
10. Talukdar MM, Vercammen JP. Evaluation of xanthan gum as a hydrophillic matrix for controlled release dosage forms. Drug Dev Ind Pharm. 1993; 19: 1037-46.
11. Talukdar MM, Mooter VD, Augustijns P, Maga TT, Verbeke N, Kinget R. In vitro evaluation of xanthan gum as potential excipients for oral controlled release matrix tablet formulation. Int J Pharm. 2000; 169: 105-113.
12. Dea ICM, A. Morrison Chemistry and interaction of seed galactomannans. Adv Carbohydrates Chemistry and Biochemistry. 1975; 31: 242-312.
13. Launay B, J. R Doublier, G. Cuvelier. Flow properties of aqueous solutions and dispersion of polysaccharides, In J r Mitchell and D. A Ledward (Eds) Functional properties of food macromolecules. Elsevier Applied Sciences, London. 1986; 1-78.
14. Reynolds JEF, Martindale. The Extra Pharmacopoeia, 30th Edition, the Pharmaceutical Press, London. 1993, P1097-1098.
15. C nota PJ et al. Tramadol Sustain release formulations: Pharmacokinetic comparison multiple unit dose (capsule) Vs a single unit dose (Tablet), Clin. Drug Invest. 2005; 25(7): 435-443.
16. nd Edition, Lea and Febiger, Philadelphia, PA, 1987; P 430-456.
17. d for the development of diltiazem HCl modified-release tablets using a 3(2) factorial design. Drug Dev Ind Pharm. 2002; 28(1): 77-87.
18. st ed. New York: Marcel Dekker Inc, 1999, P191-194.
19. Mathews BR, Regulatory aspects of stability testing in Europe. Drug Dev Ind Pharm. 1999; 25: 831-856.
20. Izhar SA, Lakshmi NM and Madhusudan YR. Formulation and Characterization of Matrix and triple layer Matrix Tablets For Oral Controlled Drug Delivery. Int J Pharmacy Pharm Sci. 2010; l 2, (3), 137-143.