Prediction of physical properties of a novel polysaccharide controlled release system. I.

International Journal of Pharmaceutics

Volumn 128, Issue 1-2, 1996, Pages 113-122

  Tobyn, Michael J ^a   Staniforth, John N ^a   Baichwal, Anand R ^b   McCall, Troy W ^b  

^a University of Bath   (United Kingdom)

^b TIMERx Technologies   (United States)

Author keywords

controlled release; hydrophilic matrix; locust bean gum; tableting; xanthan gum

Indexed keywords

GLUCOSE; POLYSACCHARIDE; TICAXAN; UNCLASSIFIED DRUG; XANTHAN;

ARTICLE; DENSITY; DRUG GRANULATION; PARTICLE SIZE; PREDICTION; PRIORITY JOURNAL; SUSTAINED RELEASE PREPARATION; TABLET MANUFACTURE; TENSILE STRENGTH;

EID: 0029968703     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(95)04230-X     Document Type: Article

References (15)

1. Baichwal, A. and Staniforth, J., Directly Compressible Sustained Release Excipient. U.S. Patent (1991) 4 994 276.
2. Baichwal, A. and Staniforth, J., Directly Compressible Sustained Release Excipient and Tablet Formulation. U.S. Patent (1992a) 5 128 143.
3. Baichwal, A. and Staniforth, J., Compressible Sustained Release Dosage Forms. U.S. Patent (1992b) 5 135 757.
4. Challinor, C.L., Staniforth, J.N. and Baichwal, A.R., Drug/ polysaccharide matrix interactions. Proc. Int. Symp. Contr. Release Bioact. Mater., 21 (1994) 748-749.
5. Hochberg, Y. and Tamhane, A.C., Multiple Comparison Procedures. Wiley, New York, 1987, p. 66.
6. Hodson, A.C., Lendrem, D.W., Mitchell, J.R., Davies, M.C. and Melia, C.D., The influence of wet granulation on the performance of xanthan gum as a hydrophilic matrix sustained release carrier. Proc. Int. Symp. Contr. Release Bioact. Mater., 21 (1994) 726-727.
7. Hogan, J.E., Hydroxypropylmethylcellulose sustained release technology. Drug Dev. Ind. Pharm., 15 (1989) 975-999.
8. Knapczyk, J., Excipient ability of chitosan for direct tableting. Int. J. Pharm., 89 (1993) 1-7.
9. Lu, M.F., Woodward, L. and Borodkin, S., Xanthan gum and alginate based controlled release theophylline formulations. Drug Dev. Ind. Pharm., 17 (1991) 1987-2004.
10. McCall, T.W. and Baichwal, A.R., In vitro-in vivo correlation of TIMERx-metoprolol products. Proc. Intern. Symp. Contr. Release Bioact. Mater., 21 (1994) 812-813.
11. Rizk, S., Duru, C., Gaudy, D., Jacob, M. and Puech, A., Natural polymer for hydrophilic matrix, scleroglucan. Pharmacotechnical characterisation and lyoavailability. STP Pharma Sci., 3 (1993) 300-306.
12. Staniforth, J.N. and Baichwal, A.R., Synergistically interacting heterodisperse polysaccharides: Function in achieving controlled drug delivery. ACS Symposium Series, No. 520 (1993), Ch. 24, pp. 327-350.
13. Talukdar, M.M. and Plaiziervercammen, J., Evaluation of xanthan gum as a hydrophilic matrix for controlled release dosage form preparations. Drug Dev. Ind. Pharm., 19 (1993) 1037-1046.
14. Upadrashta, S.M., Katikaneni, P.R., Hileman, G.A. and Keshary, P.R., Direct compression controlled release tablets using ethylcellulose matrices. Drug Dev. Ind. Pharm., 19 (1993) 449-460.
15. Waaler, P.J., Anderson, M., Graffner, C. and Muller, B.W., Influence of compaction pressure on the properties of xanthan/guar gum matrices. Acta Pharm. Nordica, 4 (1992) 167-170.