Locomotor activity and anxiety status, but not spatial working memory, are affected in mice after brief exposure to cuprizone

Neuroscience Bulletin

Volumn 29, Issue 5, 2013, Pages 633-641

  Zhang, Handi ^a,b   Zhang, Yanbo ^b   Xu, Haiyun ^a   Wang, Lingyan ^c   Zhao, Jinsong ^d   Wang, Junhui ^b   Zhang, Zhijun ^e   Tan, Qingrong ^f   Kong, Jiming ^g   Huang, Qingjun ^a   Li, Xin Min ^b  

^a SHANDONG MENTAL HEALTH CENTER   (China)

^b UNIVERSITY OF MANITOBA   (Canada)

^c JILIN UNIVERSITY   (China)

^d THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^e AFFILIATED ZHONGDA HOSPITAL OF SOUTHEAST UNIVERSITY   (China)

^f FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^g UNIVERSITY OF MANITOBA   (Canada)

Author keywords

anxiety; cuprizone; locomotor activity; mouse; myelination; oligodendrocyte; spatial working memory

Indexed keywords

CUPRIZONE; MEMBRANE PROTEIN; MYELIN BASIC PROTEIN; PROTEIN CASPR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DEMYELINATION; EMOTION; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MALE; MEMORY; MOUSE; MYELIN SHEATH; NONHUMAN; OLIGODENDROGLIA; SPATIAL WORKING MEMORY;

ANIMALS; ANXIETY; BRAIN; CHELATING AGENTS; CUPRIZONE; DISEASE MODELS, ANIMAL; MALE; MEMORY, SHORT-TERM; MENTAL DISORDERS; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; NERVE FIBERS, MYELINATED; OLIGODENDROGLIA;

EID: 84885329595     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-013-1369-0     Document Type: Article

References (28)

1. Takahashi N, Sakurai T, Davis KL, Buxbaum JD. Linking oligodendrocyte and myelin dysfunction to neurocircuitry abnormalities in schizophrenia. Prog Neurobiol 2011, 93: 13-24.
2. Mahon K, Burdick KE, Szeszko PR. A role for white matter abnormalities in the pathophysiology of bipolar disorder. Neurosci Biobehav Rev 2010, 34: 533-554.
3. Tham MW, Woon PS, Sum MY, Lee TS, Sim K. White matter abnormalities in major depression: evidence from postmortem, neuroimaging and genetic studies. J Affect Disord 2011, 132: 26-36.
4. Thomason ME, Thompson PM. Diffusion imaging, white matter, and psychopathology. Annu Rev Clin Psychol 2011, 7: 63-85.
5. D'Agati E, Casarelli L, Pitzianti MB, Pasini A. Overflow movements and white matter abnormalities in ADHD. Prog Neuropsychopharmacol Biol Psychiatry 2010, 34: 441-445.
6. Xu H, Li XM. White matter abnormalities and animal models examining a putative role of altered white matter in schizophrenia. Schizophr Res Treatment 2011, 2011:826976.
7. Hiremath MM, Saito Y, Knapp GW, Ting JP, Suzuki K, Matsushima GK. Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice. J Neuroimmunol 1998, 92: 38-49.
8. Morell P, Barrett CV, Mason JL, Toews AD, Hostettler JD, Knapp GW, et al. Gene expression in brain during cuprizoneinduced demyelination and remyelination. Mol Cell Neurosci 1998, 12: 220-227.
9. Franco-Pons N, Torrente M, Colomina MT, Vilella E. Behavioral deficits in the cuprizone-induced murine model of demyelination/remyelination. Toxicol Lett 2007, 169: 205-213.
10. Xu H, Yang HJ, Zhang Y, Clough R, Browning R, Li XM. Behavioral and neurobiological changes in C57BL/6 mice exposed to cuprizone. Behav Neurosci 2009, 123: 418-429.
11. Liu L, Belkadi A, Darnall L, Hu T, Drescher C, Cotleur AC, et al. CXCR2-positive neutrophils are essential for cuprizoneinduced demyelination: relevance to multiple sclerosis. Nat Neurosci 2010, 13: 319-326.
12. Mason JL, Jones JJ, Taniike M, Morell P, Suzuki K, Matsushima GK. Mature oligodendrocyte apoptosis precedes IGF-1 production and oligodendrocyte progenitor accumulation and differentiation during demyelination/remyelination. J Neurosci Res 2000, 61: 251-262.
13. Binder MD, Cate HS, Prieto AL, Kemper D, Butzkueven H, Gresle MM, et al. Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizoneinduced demyelination. J Neurosci 2008, 28: 5195-5206.
14. Hughes RN. The value of spontaneous alternation behavior (SAB) as a test of retention in pharmacological investigations of memory. Neurosci Biobehav Rev 2004, 28: 497-505.
15. Maurice T, Hiramatsu M, Itoh J, Kameyama T, Hasegawa T, Nabeshima T. Behavioral evidence for a modulating role of sigma ligands in memory processes. I. Attenuation of dizocilpine (MK-801)-induced amnesia. Brain Res 1994, 647: 44-56.
16. Sarter M, Bodewitz G, Stephens DN. Attenuation of scopolamine-induced impairment of spontaneous alteration behaviour by antagonist but not inverse agonist and agonist beta-carbolines. Psychopharmacology (Berl) 1988, 94: 491-495.
17. Einheber S, Zanazzi G, Ching W, Scherer S, Milner TA, Peles E, et al. The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination. J Cell Biol 1997, 139: 1495-1506.
18. Mason JL, Toews A, Hostettler JD, Morell P, Suzuki K, Goldman JE, et al. Oligodendrocytes and progenitors become progressively depleted within chronically demyelinated lesions. Am J Pathol 2004, 164: 1673-1682.
19. Yang HJ, Wang L, Cheng Q, Xu H. Abnormal behaviors and microstructural changes in white matter of juvenile mice repeatedly exposed to amphetamine. Schizophr Res Treatment 2011, 2011: 542896.
20. Xu H, Yang HJ, Rose GM, Li XM. Recovery of behavioral changes and compromised white matter in C57BL/6 mice exposed to cuprizone: effects of antipsychotic drugs. Front Behav Neurosci 2011, 5: 31.
21. Roy K, Murtie JC, El-Khodor BF, Edgar N, Sardi SP, Hooks BM, et al. Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders. Proc Natl Acad Sci U S A 2007, 104: 8131-8136.
22. Sandell JH, Peters A. Disrupted myelin and axon loss in the anterior commissure of the aged rhesus monkey. J Comp Neurol 2003, 466: 14-30.
23. Peyser JM, Edwards KR, Poser CM, Filskov SB. Cognitive function in patients with multiple sclerosis. Arch Neurol 1980, 37: 577-579.
24. Rao SM, Leo GJ, Bernardin L, Unverzagt F. Cognitive dysfunction in multiple sclerosis. I. Frequency, patterns, and prediction. Neurology 1991, 41: 685-691.
25. Liston C, Watts R, Tottenham N, Davidson MC, Niogi S, Ulug AM, et al. Frontostriatal microstructure modulates efficient recruitment of cognitive control. Cereb Cortex 2006, 16: 553-560.
26. Linares D, Taconis M, Mana P, Correcha M, Fordham S, Staykova M, et al. Neuronal nitric oxide synthase plays a key role in CNS demyelination. J Neurosci 2006, 26: 12672-12681.
27. Hesse A, Wagner M, Held J, Bruck W, Salinas-Riester G, Hao Z, et al. In toxic demyelination oligodendroglial cell death occurs early and is FAS independent. Neurobiol Dis 2010, 37: 362-369.
28. Mason JL, Ye P, Suzuki K, D'Ercole AJ, Matsushima GK. Insulin-like growth factor-1 inhibits mature oligodendrocyte apoptosis during primary demyelination. J Neurosci 2000, 20: 5703-5708.