SOX1 suppresses cell growth and invasion in cervical cancer

Gynecologic Oncology

Volumn 131, Issue 1, 2013, Pages 174-181

  Lin, Ya Wen ^a   Tsao, Chun Ming ^a   Yu, Pei Ning ^a   Shih, Yu Lueng ^b   Lin, Chia Hsin ^a   Yan, Ming De ^c  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cervical cancer; SOX1 gene; Wnt catenin signaling pathway

Indexed keywords

BETA CATENIN; CYCLIN D1; DOXYCYCLINE; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SOX1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL ANCHORAGE; CELL GROWTH; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE ACTIVITY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INDUCTION; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PHENOTYPE; PRIORITY JOURNAL; SCID MOUSE; TUMOR INVASION; TUMOR SUPPRESSOR GENE; UTERINE CERVIX CANCER;

EID: 84885324281     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2013.07.111     Document Type: Article

References (50)

1. Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001;94: 153-6.
2. Walboomers JM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 1999;189: 12-9.
3. zur Hausen H. Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J Natl Cancer Inst 2000;92: 690-8.
4. Syrjanen KJ. Spontaneous evolution of intraepithelial lesions according to the grade and type of the implicated human papillomavirus (HPV). Eur J Obstet Gynecol Reprod Biol 1996;65: 45-53.
5. Harris CP, Lu XY, Narayan G, Singh B, Murty VV, Rao PH. Comprehensive molecular cytogenetic characterization of cervical cancer cell lines. Genes Chromosomes Cancer 2003;36: 233-41.
6. Atkin NB, Baker MC. DNA ploidy of cervical intraepithelial neoplasia (CIN). Cancer Genet Cytogenet 1997;94: 151-2.
7. Sova P, Feng Q, Geiss G,Wood T, Strauss R, Rudolf V, et al. Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis. Cancer Epidemiol Biomarkers Prev 2006;15: 114-23.
8. Feng Q, Balasubramanian A, Hawes SE, Toure P, Sow PS, Dem A, et al. Detection of hypermethylated genes inwomenwith and without cervical neoplasia. J Natl Cancer Inst 2005;97: 273-82.
9. Steenbergen RD, Kramer D, Braakhuis BJ, Stern PL, Verheijen RH, Meijer CJ, et al. TSLC1 gene silencing in cervical cancer cell lines and cervical neoplasia. J Natl Cancer Inst 2004;96: 294-305.
10. Lai HC, Lin YW, Huang TH, Yan P, Huang RL, Wang HC, et al. Identification of novel DNA methylation markers in cervical cancer. Int J Cancer 2008;123: 161-7.
11. Cohen Y, Singer G, Lavie O, Dong SM, Beller U, Sidransky D. The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix. Clin Cancer Res 2003;9: 2981-4.
12. Jung S, Jeong D, Kim J, Yi L, Koo K, Lee J, et al. Epigenetic regulation of the potential tumor suppressor gene, hLHX6.1, in human cervical cancer. Int J Oncol 2011;38: 859-69.
13. Lai HC, Lin YW, Chang CC,Wang HC, Chu TW, YuMH, et al. Hypermethylation of two consecutive tumor suppressor genes, BLU and RASSF1A, located at 3p21.3 in cervical neoplasias. Gynecol Oncol 2007;104: 629-35.
14. Liu CY, Chao TK, Su PH, Lee HY, Shih YL, Su HY, et al. Characterization of LMX-1A as a metastasis suppressor in cervical cancer. J Pathol 2009;219: 222-31.
15. Narayan G, Scotto L, Neelakantan V, Kottoor SH, Wong AH, Loke SL, et al. Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer. Genes Chromosomes Cancer 2009;48: 983-92.
16. Pfeifer GP, Dammann R. Methylation of the tumor suppressor gene RASSF1A in human tumors. Biochemistry (Mosc) 2005;70: 576-83.
17. Shu XS, Geng H, Li L, Ying J, Ma C, Wang Y, et al. The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/beta-catenin signaling and is frequently silenced in multiple tumors. PLoS One 2011;6:e27346.
18. Henken FE, Wilting SM, Overmeer RM, van Rietschoten JG, Nygren AO, Errami A, et al. Sequential gene promoter methylation during HPV-induced cervical carcinogenesis. Br J Cancer 2007;97: 1457-64.
19. Overmeer RM, Henken FE, Bierkens M, Wilting SM, Timmerman I, Meijer CJ, et al. Repression ofMAL tumour suppressor activity by promotermethylation during cervical carcinogenesis. J Pathol 2009;219: 327-36.
20. Overmeer RM, Henken FE, Snijders PJ, Claassen-Kramer D, Berkhof J, Helmerhorst TJ, et al. Association between dense CADM1 promotermethylation and reduced protein expression in high-grade CIN and cervical SCC. J Pathol 2008;215: 388-97.
21. Huang RL, Chang CC, Su PH, Chen YC, Liao YP, Wang HC, et al. Methylomic analysis identifies frequent DNA methylation of zinc finger protein 582 (ZNF582) in cervical neoplasms. PLoS One 2012;7:e41060.
22. Lai HC, Lin YW, Huang RL, Chung MT, Wang HC, Liao YP, et al. Quantitative DNA methylation analysis detects cervical intraepithelial neoplasms type 3 and worse. Cancer 2010;116: 4266-74.
23. Chung MT, Lai HC, Sytwu HK, Yan MD, Shih YL, Chang CC, et al. SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway. Gynecol Oncol 2009;112: 646-53.
24. Uren A, Fallen S, Yuan H, Usubutun A, Kucukali T, Schlegel R, et al. Activation of the canonicalWnt pathway during genital keratinocyte transformation: amodel for cervical cancer progression. Cancer Res 2005;65: 6199-206.
25. Giles RH, van Es JH, Clevers H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta 2003;1653: 1-24.
26. Dann CE, Hsieh JC, Rattner A, Sharma D, Nathans J, Leahy DJ. Insights intoWnt binding and signalling from the structures of two Frizzled cysteine-rich domains. Nature 2001;412: 86-90.
27. Hsieh JC, Rattner A, Smallwood PM, Nathans J. Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrateWnt protein. Proc Natl Acad Sci U S A 1999;96: 3546-51.
28. Behrens J, vonKries JP,KuhlM,BruhnL,WedlichD, GrosschedlR, etal. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996;382: 638-42.
29. Wodarz A, Nusse R. Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 1998;14: 59-88.
30. Cadigan KM, Nusse R. Wnt signaling: a common theme in animal development. Genes Dev 1997;11: 3286-305.
31. Mann B, Gelos M, Siedow A, Hanski ML, Gratchev A, Ilyas M, et al. Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc Natl Acad Sci U S A 1999;96: 1603-8.
32. Lin YW, Chung MT, Lai HC, De Yan M, Shih YL, Chang CC, et al. Methylation analysis of SFRP genes family in cervical adenocarcinoma. J Cancer Res Clin Oncol 2009;135: 1665-74.
33. Chung MT, Sytwu HK, Yan MD, Shih YL, Chang CC, Yu MH, et al. Promoter methylation of SFRPs gene family in cervical cancer. Gynecol Oncol 2009;112: 301-6.
34. Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, et al. Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev 2004;18: 1072-87.
35. Sinner D, Kordich JJ, Spence JR, Opoka R, Rankin S, Lin SCJ, et al. Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol Cell Biol 2007;27: 7802-15.
36. Schepers GE, Teasdale RD, Koopman P. Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. Dev Cell 2002;3: 167-70.
37. Buescher M, Hing FS, ChiaW. Formation of neuroblasts in the embryonic central nervous system of Drosophila melanogaster is controlled by SoxNeuro. Development 2002;129: 4193-203.
38. Kan L, Israsena N, Zhang Z, Hu M, Zhao L-R, Jalali A, et al. Sox1 acts through multiple independent pathways to promote neurogenesis. Dev Biol 2004;269: 580-94.
39. Tsao CM, Yan MD, Shih YL, Yu PN, Kuo CC, Lin WC, et al. SOX1 functions as a tumor suppressor by antagonizing the WNT/beta-catenin signaling pathway in hepatocellular carcinoma. Hepatology 2012;56: 2277-87.
40. Su HY, Lai HC, Lin YW, Chou YC, Liu CY, Yu MH. An epigenetic marker panel for screening and prognostic prediction of ovarian cancer. Int J Cancer 2009;124: 387-93.
41. ShihYL,HsiehCB, LaiHC,YanMD, HsiehTY, ChaoYC,et al. SFRP1suppressedhepatoma cells growth throughWnt canonical signaling pathway. Int J Cancer 2007;121: 1028-35.
42. Mikheev AM, Mikheeva SA, Liu B, Cohen P, Zarbl H. A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation. Carcinogenesis 2004;25: 47-59.
43. Shinohara A, Yokoyama Y, Wan X, Takahashi Y, Mori Y, Takami T, et al. Cytoplasmic/nuclear expression without mutation of exon 3 of the beta-catenin gene is frequent in the development of the neoplasm of the uterine cervix. Gynecol Oncol 2001;82: 450-5.
44. Stein RA. Epigenetics - the link between infectious diseases and cancer. JAMA 2011;305: 1484-5.
45. Kormish JD, Sinner D, Zorn AM. Interactions between SOX factors and Wnt/betacatenin signaling in development and disease. Dev Dyn 2010;239: 56-68.
46. Guo L, Zhong D, Lau S, Liu X, Dong XY, Sun X, et al. Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Mol Cancer Res 2008;6: 1421-30.
47. ZhangW, Glockner SC, Guo M,Machida EO,Wang DH, Easwaran H, et al. Epigenetic inactivation of the canonicalWnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res 2008;68: 2764-72.
48. Mathews LA, Hurt EM, Zhang X, Farrar WL. Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells. Mol Cancer 2010;9:267.
49. Semenov MV, Habas R, Macdonald BT, He X. SnapShot: noncanonical Wnt signaling pathways. Cell 2007;131:1378.
50. Jordan NV, Prat A, Abell AN, Zawistowski JS, Sciaky N, Karginova OA, et al. SWI/SNF chromatin-remodeling factor Smarcd3/Baf60c controls epithelial-mesenchymal transition by inducingWnt5a signaling. Mol Cell Biol 2013;33: 3011-25.