Various models of cardiac conditioning in single or sequential periods of ischemia: Comparative effects on infarct size and intracellular signaling

International Journal of Cardiology

Volumn 168, Issue 2, 2013, Pages 1336-1341

  Iliodromitis, Konstantinos ^a   Farmakis, Dimitrios ^a   Andreadou, Ioanna ^b   Zoga, Anastasia ^a   Bibli, Sofia Iris ^b   Manolaki, Theodora ^a   Dagres, Nikolaos ^a   Iliodromitis, Efstathios K ^a   Anastasiou Nana, Maria ^a   Kremastinos, Dimitrios Th ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

Infarct size; Intracellular signaling; Ischemia; Postconditioning; Preconditioning; Reperfusion

Indexed keywords

PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART RATE; HEART WEIGHT; IN VIVO STUDY; INTRACELLULAR SIGNALING; ISCHEMIC POSTCONDITIONING; ISCHEMIC PRECONDITIONING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; WESTERN BLOTTING;

INFARCT SIZE; INTRACELLULAR SIGNALING; ISCHEMIA; POSTCONDITIONING; PRECONDITIONING; REPERFUSION;

ANIMALS; DISEASE MODELS, ANIMAL; INTRACELLULAR FLUID; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; RABBITS; RANDOM ALLOCATION; SIGNAL TRANSDUCTION; TIME FACTORS; TREATMENT OUTCOME;

EID: 84885322165     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.12.014     Document Type: Article

References (37)

1. Murry CE, Jennings RB, Reimer KA. Preconditioning with Ischemia: a delay of lethal cell Injury In Ischemic myocardium. Circulation 1986;74:1124-36.
2. Zhao Z-Q, Corvera JS, Halkos ME, et al. Inhibition of myocardial Injury by Ischemic postconditioning during Reperfusion: comparison with Ischemic preconditioning. Am J Physiol Heart Circ Physiol 2003;285:H579-88.
3. Przyklenk K, Bauer B, Ovize M, Kloner RA, Whittaker P. Regional Ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion. Circulation 1993;87:893-9.
4. Gritsopoulos G, Iliodromitis EK, Zoga A, et al. Remote postconditioning Is more potent than classic postconditioning In reducing the Infarct size In anesthetized rabbits. Cardiovasc Drugs Ther 2009;23:193-8.
5. Yellon DM, Hausenloy DJ. Myocardial Reperfusion Injury. N Engl J Med 2007;357: 1121-35.
6. Iliodromitis EK, Kremastinos DT, Katritsis DG, Papadopoulos CC, Hearse DJ. Multiple cycles of preconditioning cause loss of protection In open-chest rabbits. J Mol Cell Cardiol 1997;29:915-20.
7. Thornton JD, Liu GS, Olsson RA, Downey JM. Intravenous pretreatment with A1-selective adenosine analogues protects the heart against Infarction. Circulation 1992;85:659-65.
8. Andreadou I, Iliodromitis EK, Koufaki M, Kremastinos DTh. Pharmacological preand post-conditioning agents: Reperfusion-injury of the heart revisited. Mini Rev Med Chem 2008;8:952-9.
9. Iliodromitis EK, Andreadou I, Prokovas E, et al. Simvastatin In contrast to postconditioning reduces Infarct size In hyperlipidemic rabbits: possible role of oxidative/nitrosative stress. Basic Res Cardiol 2010;105:193-203.
10. Downey JM, Cohen MV. Why do we still not have cardioprotective drugs? Circ J 2009;73:1171-7.
11. Hausenloy DJ, Yellon DM. Reperfusion Injury salvage kinase signalling: taking a RiSK for cardioprotection. Heart Fail Rev 2007;12:217-34.
12. Hausenloy DJ, Tsang A, Mocanu M, Yellon DM. Ischemic preconditioning protects by activating pro-survival kinases at Reperfusion. Am J Physiol Heart Circ Physiol 2005;288:H971-6.
13. Tsang A, Hausenloy DJ, Mocanu MM, Yellon DM. Postconditioning: a form of "modified Reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway. Circ Res 2004;95:230-2.
14. Mahaffey KW, Puma JA, Barbagelata NA, et al. Adenosine as an adjunct to thrombolytic therapy for acute myocardial Infarction: results of a multicenter, randomized, placebo-controlled trial: the Acute Myocardial Infarction STudy of ADenosine (AMiSTAD) trial. J Am Coll Cardiol 1999;34:1711-20.
15. Ross AM, Gibbons RJ, Stone GW, Kloner RA, Alexander RW. AMiSTAD-ii Investigators. A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to Reperfusion In the treatment of acute myocardial Infarction (AMiSTAD-ii). J Am Coll Cardiol 2005;45:1775-80.
16. Gomez L, Li B, Mewton N, et al. Inhibition of mitochondrial permeability transition pore opening: translation to patients. Cardiovasc Res 2009;83:226-33.
17. Ivanes F, Rioufol G, Piot C, Ovize M. Postconditioning In acute myocardial Infarction patients. Antioxid Redox Signal 2011;14:811-20.
18. Hansen RR, Thibault H, Abdulla J. Postconditioning during primary percutaneous coronary Intervention: a review and meta-analysis. Int J Cardiol 2010;144:22-5.
19. Andreadou I, Iliodromitis EK, Souridis V, et al. Investigating the effect of antioxidant treatment on the protective effect of preconditioning In anesthetized rabbits. J Cardiovasc Pharmacol 2011;58:609-16.
20. Andreadou I, Farmakis D, Prokovas E, et al. Short-term statin administration In hypercholesterolemic rabbits resistant to postconditioning: effects on Infarct size, endothelial nitric oxide synthase and nitro-oxidative stress. Cardiovasc Res 2012;94:501-9.
21. Heusch G. Reduction of Infarct size by Ischaemic post-conditioning In humans: fact or fiction? Eur Heart J 2012;33:13-5.
22. Cohen MV, Downey JM. Cardioprotection: spotlight on PKG. Br J Pharmacol 2007;152:833-4.
23. Skyschally A, van Caster P, Boengler K, et al. Ischemic postconditioning In pigs: no causal role for RiSK activation. Circ Res 2009;104:15-8.
24. Ovize M, Aupetit JF, Rioufol G, et al. Preconditioning reduces Infarct size but accelerates time to ventricular fibrillation In Ischemic pig heart. Am J Physiol 1995;269:H72-9.
25. Dickson EW, Whittaker P, Darling CE, Hirsch DJ, Blehar DJ, Przyklenk K. Brief apnea Induces myocardial Ischemic tolerance by an opioid-insensitive mechanism. Cardiovasc Pathol 2004;13:225-9.
26. Zheng Z, Yang M, Zhang F, et al. Gender-related difference of sevoflurane postconditioning In Isolated rat hearts: focus on phosphatidylinositol-3- kinase/Akt signaling. J Surg Res 2011;170:e3-9.
27. Inserte J, Barba I, Hernando V, Garcia-Dorado D. Delayed recovery of Intracellular acidosis during Reperfusion prevents calpain activation and determines protection In postconditioned myocardium. Cardiovasc Res 2009;81:116-22.
28. Skyschally A, van Caster P, Iliodromitis EK, Schulz R, Kremastinos DT, Heusch G. Ischemic postconditioning: experimental models and protocol algorithms. Basic Res Cardiol 2009;104:469-83.
29. ManIntveld OC, Te LIntelHM, van den Bos EJ, et al. Cardiac effects of postconditioning depend critically on the duration of Index Ischemia. Am J Physiol Heart Circ Physiol 2007;292:H1551-60.
30. Schwartz LM, Lagranha CJ. Ischemic postconditioning during Reperfusion activates Akt and ERK without protecting against lethal myocardial Ischemia-Reperfusion Injury In pigs. Am J Physiol Heart Circ Physiol 2006;290:H1011-8.
31. Hausenloy DJ, Tsang A, Yellon DM. The Reperfusion Injury salvage kinase pathway: a common target for both Ischemic preconditioning and postconditioning. Trends Cardiovasc Med 2005;15:69-75.
32. Heusch G, Boengler K, Schulz R. Cardioprotection, nitric oxide, protein kinases and mitochondria. Circulation 2008;118:1915-9.
33. Boengler K, Hilfiker-Kleiner D, Drexler H, Heusch G, Schulz R. The myocardial JAK/STAT pathway: from protection to failure. Pharmacol Ther 2008;120: 172-85.
34. HalkosME, Kerendi F, Corvera JS, et al. Myocardial protection with postconditioning Is not enhanced by Ischemic preconditioning. Ann Thorac Surg 2004;78:961-9.
35. Yang XM, Proctor JB, Cui L, Krieg T, Downey JM, Cohen MV. Multiple, brief coronary occlusions during early Reperfusion protect rabbit hearts by targeting cell signaling pathways. J Am Coll Cardiol 2004;44:1103-10.
36. Kim SO, Baines CP, Critz SD, et al. Ischemia Induced activation of heat shock protein 27 kinases and casein kinase 2 In the preconditioned rabbit heart. Biochem Cell Biol 1999;77:559-67.
37. Iliodromitis EK, Downey JM, Heusch G, Kremastinos DTh. What Is the optimal postconditioning algorithm? J Cardiovasc Pharmacol Ther 2009;14:269-73.