CXCR6 deficiency ameliorated myocardial ischemia/reperfusion injury by inhibiting infiltration of monocytes and IFN-γ-dependent autophagy

International Journal of Cardiology

Volumn 168, Issue 2, 2013, Pages 853-862

  Zhao, Gang ^a   Wang, Shijun ^a,b   Wang, Zhen ^a   Sun, Aijun ^a   Yang, Xiangdong ^a   Qiu, Zhaohui ^a,c   Wu, Chaoneng ^a,b   Zhang, Wenbin ^a,b   Li, Hua ^a   Zhang, Youen ^a   Zhao, Jingjing ^a   Zou, Yunzeng ^a,b   Ge, Junbo ^a,b  

^a ZHONGSHAN HOSPITAL OF FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c HUADONG HOSPITAL AFFILIATED TO FUDAN UNIVERSITY   (China)

Author keywords

Autophagy; CXCL16; CXCR6; IFN ; Ischemia reperfusion injury

Indexed keywords

CD11B ANTIGEN; CHEMOKINE RECEPTOR CXCR6; CXCL16 CHEMOKINE; GAMMA INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; HEART INFARCTION SIZE; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE SYSTOLIC PRESSURE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEMODYNAMIC PARAMETERS; KNOCKOUT MOUSE; LEFT VENTRICULAR FRACTION SHORTENING; MALE; MONOCYTE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL;

AUTOPHAGY; CXCL16; CXCR6; IFN-Γ; ISCHEMIA/REPERFUSION INJURY;

ANIMALS; AUTOPHAGY; CELL MIGRATION INHIBITION; COCULTURE TECHNIQUES; INTERFERON-GAMMA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; MYOCARDIAL REPERFUSION INJURY; RECEPTORS, CXCR;

EID: 84885309982     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.10.022     Document Type: Article

References (44)

1. Yellon DM, Hausenloy DJ. Myocardial reperfusion injury. N Engl J Med 2007;357(11):1121-35.
2. Hansen PR. Role of neutrophils in myocardial ischemia and reperfusion. Circulation 1995;91(6):1872-85.
3. Jordan JE, Zhao ZQ, Vinten-Johansen J. The role of neutrophils in myocardial ischemia-reperfusion injury. Cardiovasc Res 1999;43(4):860-78.
4. Seizer P, Stellos K, Selhorst G, et al. CXCL16 is a novel scavenger receptor on platelets and is associated with acute coronary syndrome. Thromb Haemost 2011;105(6): 1112-4.
5. Jansson AM, Aukrust P, Ueland T, et al. Soluble CXCL16 predicts long-term mortality in acute coronary syndromes. Circulation 2009;119(25):3181-8.
6. Sheikine Y, Bang CS, Nilsson L, et al. Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease. Atherosclerosis 2006;188(2): 462-6.
7. Yamauchi R, Tanaka M, Kume N, et al. Upregulation of SR-PSOX/CXCL16 and recruitment of CD8+ T cells in cardiac valves during inflammatory valvular heart disease. Arterioscler Thromb Vasc Biol 2004;24(2):282-7.
8. Sato T, Thorlacius H, Johnston B, et al. Role for CXCR6 in recruitment of activated CD8+ lymphocytes to inflamed liver. J Immunol 2005;174(1):277-83.
9. Kume N. New oxidized LDL receptors and their functions in atherogenesis. Nihon Ronen Igakkai Zasshi 2002;39(3):264-7.
10. Jiang X, Sun W, Zhu L, et al. Expression of CXCR6 on CD8(+) T cells was up-regulated in allograft rejection. Transpl Immunol 2010;22(3-4):179-83.
11. Galkina E, Harry BL, Ludwig A, et al. CXCR6 promotes atherosclerosis by supporting T-cell homing, interferon-gamma production, and macrophage accumulation in the aortic wall. Circulation 2007;116(16):1801-11.
12. Dahl CP, Husberg C, Gullestad L, et al. Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling. Circ Heart Fail 2009;2(6):624-32.
13. Szmit S, Jank M, Maciejewski H, et al. Gene expression profiling in peripheral blood nuclear cells in patients with refractory ischaemic end-stage heart failure. J Appl Genet 2010;51(3):353-68.
14. Darash-Yahana M, Gillespie JW, Hewitt SM, et al. The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers. PLoS One 2009;4(8):e6695.
15. Cullen R, Germanov E, Shimaoka T, Johnston B. Enhanced tumor metastasis in response to blockade of the chemokine receptor CXCR6 is overcome by NKT cell activation. J Immunol 2009;183(9):5807-15.
16. Valentim L, Laurence KM, Townsend PA, et al. Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury. J Mol Cell Cardiol 2006;40:846-52.
17. Feng CG, Zheng L, Jankovic D, et al. The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gammainduced cell death. Nat Immunol 2008;9(11):1279-87.
18. Wang J, Lu Y, Wang J, Koch AE, Zhang J, Taichman RS. CXCR6 induces prostate cancer progression by the AKT/mammalian target of rapamycin signaling pathway. Cancer Res 2008;68(24):10367-76.
19. Shan X, Xu X, Cao B, et al. Transcription factor GATA-4 is involved in erythropoietininduced cardioprotection against myocardial ischemia/reperfusion injury. Int J Cardiol 2009;134(3):384-92.
20. Li J, Goser S, Leuschner F, et al. Mucosal tolerance induction in autoimmune myocarditis and myocardial infarction. Int J Cardiol 2011. http://dx.doi.org/10. 1016/j.ijcard.2011.05.057.
21. Lin L, Gong H, Ge J, et al. High density lipoprotein downregulates angiotensin II type 1 receptor and inhibits angiotensin II-induced cardiac hypertrophy. Biochem Biophys Res Commun 2011;404(1):28-33.
22. Matsui Y, Takagi H, Qu X, et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 2007;100(6):914-22.
23. Polyakova V, Loeffler I, Hein S, et al. Fibrosis in endstage human heart failure: severe changes in collagen metabolism and MMP/TIMP profiles. Int J Cardiol 2011;151(1): 18-33.
24. Yan D, Wang X, Li D, et al. Macrophages overexpressing VEGF target to infarcted myocardium and improve neovascularization and cardiac function. Int J Cardiol 2011. http://dx.doi.org/10.1016/j.ijcard.2011.07.026.
25. Lu W, Fu C, Song L, et al. Exposure to supernatants of macrophages that phagocytized dead mesenchymal stem cells improves hypoxic cardiomyocytes survival. Int J Cardiol 2012. http://dx.doi.org/10.1016/j.ijcard.2012.03.088.
26. Zujovic V, Taupin V. Use of cocultured cell systems to elucidate chemokine-dependent neuronal/microglial interactions: control ofmicroglial activation. Methods 2003;29(4): 345-50.
27. Valaperti A, Marty RR, Kania G, et al. CD11b+ monocytes abrogate Th17 CD4+ T cell-mediated experimental autoimmune myocarditis. J Immunol 2008;180(4): 2686-95.
28. Ma H, Guo R, Yu L, Zhang Y, Ren J. Aldehyde dehydrogenase 2 (ALDH2) rescuesmyocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde. Eur Heart J 2011;32(8):1025-38.
29. Khalkhali-Ellis Z, Abbott DE, Bailey CM, et al. IFN-gamma regulation of vacuolar pH, cathepsin D processing and autophagy in mammary epithelial cells. J Cell Biochem 2008;105(1):208-18.
30. Chang YP, Chen CL, Chen SO, et al. Autophagy facilitates an IFN-gamma response and signal transduction. Microbes Infect 2011;13(11):888-94.
31. Feng CG, Zheng L, Lenardo MJ, Sher A. Interferon-inducible immunity-related GTPase Irgm1 regulates IFN gamma-dependent host defense, lymphocyte survival and autophagy. Autophagy 2009;5(2):232-4.
32. Tabata S, Kadowaki N, Kitawaki T, et al. Distribution and kinetics of SR-PSOX/CXCL16 and CXCR6 expression on human dendritic cell subsets and CD4+ T cells. J Leukoc Biol 2005;77(5):777-86.
33. Minami M, Kume N, Shimaoka T, et al. Expression of SR-PSOX, a novel cell-surface scavenger receptor for phosphatidylserine and oxidized LDL in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2001;21(11):1796-800.
34. Paust S, Gill HS, Wang BZ, et al. Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses. Nat Immunol 2010;11(12):1127-35.
35. Zhang Y, Sun Q, He B, Xiao J, Wang Z, Sun X. Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. Int J Cardiol 2011;148(1):91-5.
36. BujakM, Kweon HJ, Chatila K, Li N, Taffet G, Frangogiannis NG. Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J Am Coll Cardiol 2008;51(14):1384-92.
37. Xu H, Yao Y, Su Z, et al. Endogenous HMGB1 contributes to ischemia-reperfusioninduced myocardial apoptosis by potentiating the effect of TNF-aα/JNK. Am J Physiol Heart Circ Physiol 2011;300(3):H913-21.
38. Gu Q, Yang XP, Bonde P, DiPaula A, Fox-Talbot K, Becker LC. Inhibition of TNF-alpha reduces myocardial injury and proinflammatory pathways following ischemia-reperfusion in the dog. J Cardiovasc Pharmacol 2006;48(6):320-8.
39. Tenger C, Sundborger A, Jawien J, Zhou X. IL-18 accelerates atherosclerosis accompanied by elevation of IFN-gamma and CXCL16 expression independently of T cells. Arterioscler Thromb Vasc Biol 2005;25(4):791-6.
40. Abel S, Hundhausen C,Mentlein R, et al. The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10. J Immunol 2004;172(10):6362-72.
41. Wuttge DM, Zhou X, Sheikine Y, et al. CXCL16/SR-PSOX is an interferon-gammaregulated chemokine and scavenger receptor expressed in atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2004;24(4):750-5.
42. Gustafsson AB, Gottlieb RA. Eat your heart out: Role of autophagy in myocardial ischemia/reperfusion. Autophagy 2008;4(4):416-21.
43. Matsui Y, Kyoi S, TakagiH, et al.Molecularmechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion. Autophagy 2008;4(4): 409-15.
44. Hariharan N, Zhai P, Sadoshima J. Oxidative stress stimulates autophagic flux during ischemia/reperfusion. Antioxid Redox Signal 2011;14(11):2179-90.