메뉴 건너뛰기




Volumn 48, Issue 2, 2013, Pages 333-339

The macamide N-3-methoxybenzyl-linoleamide is a time-dependent fatty acid amide hydrolase (FAAH) inhibitor

Author keywords

Fatty acid amide hydrolase inhibitor; Maca; Macamide N 3 methoxybenzyl linoleamide

Indexed keywords

ACYLGLYCEROL LIPASE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; FATTY ACID AMIDASE INHIBITOR; N 3 METHOXYBENZYL LINOLEAMIDE; NEUROPROTECTIVE AGENT; UNCLASSIFIED DRUG;

EID: 84885305898     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8499-2     Document Type: Conference Paper
Times cited : (37)

References (42)
  • 2
    • 77954005838 scopus 로고    scopus 로고
    • Neuroprotective effects of Lepidium meyenii (Maca)
    • 20633111 10.1111/j.1749-6632.2009.05174.x
    • Pino-Figueroa A, Nguyen D, Maher TJ (2010) Neuroprotective effects of Lepidium meyenii (Maca). Ann N Y Acad Sci 1199:77-85
    • (2010) Ann N y Acad Sci , vol.1199 , pp. 77-85
    • Pino-Figueroa, A.1    Nguyen, D.2    Maher, T.J.3
  • 3
    • 84881368172 scopus 로고    scopus 로고
    • Mechanism of action of Lepidium meyenii (Maca): An explanation for its neuroprotective activity
    • 10.1166/ajnn.2011.1035
    • Pino-Figueroa A, Vu H, Kelley CJ, Maher TJ (2011) Mechanism of action of Lepidium meyenii (Maca): an explanation for its neuroprotective activity. Am J Neuroprotec Neuroregen 3:87-92
    • (2011) Am J Neuroprotec Neuroregen , vol.3 , pp. 87-92
    • Pino-Figueroa, A.1    Vu, H.2    Kelley, C.J.3    Maher, T.J.4
  • 5
    • 84959203312 scopus 로고    scopus 로고
    • Fatty acid amide hydrolase (FAAH) inhibitors: Discovery in Lepidium meyenii (Maca) extracts
    • Weber State University, Utah, 29-31 March 2012, 410-417
    • Vu H., (2012) Fatty acid amide hydrolase (FAAH) inhibitors: discovery in Lepidium meyenii (Maca) extracts. In: Conference Proceedings of The National Conference On Undergraduate Research (NCUR), Weber State University, Utah, 29-31 March 2012, 410-417
    • (2012) Conference Proceedings of the National Conference on Undergraduate Research (NCUR)
    • Vu, H.1
  • 6
    • 0037161476 scopus 로고    scopus 로고
    • Endocannabinoids and neuroprotection
    • 10.1126/stke.2002.129.re5
    • Mechoulam R, Spatz M, Shohami E (2002) Endocannabinoids and neuroprotection. Sci STKE 2002:1-6
    • (2002) Sci STKE , vol.2002 , pp. 1-6
    • Mechoulam, R.1    Spatz, M.2    Shohami, E.3
  • 7
    • 0034766553 scopus 로고    scopus 로고
    • Pharmacological actions and therapeutic uses of cannabis and cannabinoids
    • 11703238 10.1046/j.1365-2044.2001.02269.x 1:CAS:528:DC%2BD3MXoslSqtrc%3D
    • Kumar RN, Chambers WA, Pertwee RG (2001) Pharmacological actions and therapeutic uses of cannabis and cannabinoids. Anaesthesia 56:1059-1068
    • (2001) Anaesthesia , vol.56 , pp. 1059-1068
    • Kumar, R.N.1    Chambers, W.A.2    Pertwee, R.G.3
  • 8
    • 30444457225 scopus 로고    scopus 로고
    • Cannabinoid pharmacology: The first 66 years
    • 16402100 1:CAS:528:DC%2BD28XisVCntQ%3D%3D
    • Pertwee RG (2006) Cannabinoid pharmacology: the first 66 years. Br J Pharmacol 147(Suppl 1):S163-S171
    • (2006) Br J Pharmacol , vol.147 , Issue.SUPPL. 1
    • Pertwee, R.G.1
  • 9
    • 0031660109 scopus 로고    scopus 로고
    • Cannabinoid receptor activation differentially regulates the various adenylyl cyclase isozymes
    • 9751186 10.1046/j.1471-4159.1998.71041525.x 1:CAS:528:DyaK1cXmt1Kitro%3D
    • Rhee MH, Bayewitch M, Avidor-Reiss T, Levy R, Vogel Z (1998) Cannabinoid receptor activation differentially regulates the various adenylyl cyclase isozymes. J Neurochem 71:1525-1534
    • (1998) J Neurochem , vol.71 , pp. 1525-1534
    • Rhee, M.H.1    Bayewitch, M.2    Avidor-Reiss, T.3    Levy, R.4    Vogel, Z.5
  • 10
    • 0037661996 scopus 로고    scopus 로고
    • Role of endogenous cannabinoids in synaptic signaling
    • 12843414 1:CAS:528:DC%2BD3sXmtVGmsLk%3D
    • Freund TF, Katona I, Piomelli D (2003) Role of endogenous cannabinoids in synaptic signaling. Physiol Rev 83:1017-1066
    • (2003) Physiol Rev , vol.83 , pp. 1017-1066
    • Freund, T.F.1    Katona, I.2    Piomelli, D.3
  • 11
    • 0034986485 scopus 로고    scopus 로고
    • Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide
    • 11353795 1:CAS:528:DC%2BD3MXktVahsr8%3D
    • Day TA, Rakhshan F, Deutsch DG, Barker EL (2001) Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. Mol Pharmacol 59:1369-1375
    • (2001) Mol Pharmacol , vol.59 , pp. 1369-1375
    • Day, T.A.1    Rakhshan, F.2    Deutsch, D.G.3    Barker, E.L.4
  • 12
    • 79960333360 scopus 로고    scopus 로고
    • Endocannabinoids and traumatic brain injury
    • 21418185 10.1111/j.1476-5381.2011.01343.x 1:CAS:528:DC%2BC3MXps1Sjur4%3D
    • Shohami E, Cohen-Yeshurun A, Magid L, Algali M, Mechoulam R (2011) Endocannabinoids and traumatic brain injury. Br J Pharmacol 163:1402-1410
    • (2011) Br J Pharmacol , vol.163 , pp. 1402-1410
    • Shohami, E.1    Cohen-Yeshurun, A.2    Magid, L.3    Algali, M.4    Mechoulam, R.5
  • 13
    • 24644450190 scopus 로고    scopus 로고
    • Cannabinoid receptors and their role in neuroprotection
    • 10.1385/NMM:7:1-2:037
    • van der Stelt M, Di Marzo V (2005) Cannabinoid receptors and their role in neuroprotection. Neuromol Med 7:37-50
    • (2005) Neuromol Med , vol.7 , pp. 37-50
    • Van Der Stelt, M.1    Di Marzo, V.2
  • 14
    • 77953712552 scopus 로고    scopus 로고
    • Modulation of the endocannabinoid system: Neuroprotection or neurotoxicity?
    • 20353772 10.1016/j.expneurol.2010.03.021 1:CAS:528:DC%2BC3cXnsVaqsrs%3D
    • Fowler CJ, Rojo ML, Rodriguez-Gaztelumendi A (2010) Modulation of the endocannabinoid system: neuroprotection or neurotoxicity? Exp Neurol 224:37-47
    • (2010) Exp Neurol , vol.224 , pp. 37-47
    • Fowler, C.J.1    Rojo, M.L.2    Rodriguez-Gaztelumendi, A.3
  • 15
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target of pharmacotherapy
    • 16968947 10.1124/pr.58.3.2 1:CAS:528:DC%2BD28XhtVOhtLfO
    • Pacher P, Bátkai S, Kunos G (2006) The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 58:389-462
    • (2006) Pharmacol Rev , vol.58 , pp. 389-462
    • Pacher, P.1    Bátkai, S.2    Kunos, G.3
  • 16
    • 77950692040 scopus 로고    scopus 로고
    • Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: A neuroprotective therapeutic modality
    • 19527737 10.1016/j.lfs.2009.06.003 1:CAS:528:DC%2BC3cXktlChs7g%3D
    • Hwang J, Adamson C, Butler D, Janero DR, Makriyannis A, Bahr BA (2010) Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality. Life Sci 86:615-623
    • (2010) Life Sci , vol.86 , pp. 615-623
    • Hwang, J.1    Adamson, C.2    Butler, D.3    Janero, D.R.4    Makriyannis, A.5    Bahr, B.A.6
  • 17
    • 0035150352 scopus 로고    scopus 로고
    • Cannabinoid receptors and pain
    • 11164622 10.1016/S0301-0082(00)00031-9 1:CAS:528:DC%2BD3MXntlOksA%3D%3D
    • Pertwee RG (2001) Cannabinoid receptors and pain. Prog Neurobiol 63:569-611
    • (2001) Prog Neurobiol , vol.63 , pp. 569-611
    • Pertwee, R.G.1
  • 19
    • 0042320663 scopus 로고    scopus 로고
    • Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility
    • 12944505 1:CAS:528:DC%2BD3sXmvFGhtb0%3D
    • Franklin A, Parmentier-Batteur S, Walter L, Greenberg DA, Stella N (2003) Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility. J Neurosci 23:7767-7775
    • (2003) J Neurosci , vol.23 , pp. 7767-7775
    • Franklin, A.1    Parmentier-Batteur, S.2    Walter, L.3    Greenberg, D.A.4    Stella, N.5
  • 20
    • 54549098992 scopus 로고    scopus 로고
    • Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia
    • 18823959 10.1016/j.brainres.2008.09.019 1:CAS:528:DC%2BD1cXhtlaqurjK
    • Schomacher M, Muller HD, Sommer C, Schwab S, Schabitz WR (2008) Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia. Brain Res 1240:213-220
    • (2008) Brain Res. , vol.1240 , pp. 213-220
    • Schomacher, M.1    Muller, H.D.2    Sommer, C.3    Schwab, S.4    Schabitz, W.R.5
  • 21
    • 33745066140 scopus 로고    scopus 로고
    • Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage
    • 16682966 10.1038/sj.bjp.0706755 1:CAS:528:DC%2BD28XlsV2rsrw%3D
    • Shouman B, Fontaine RH, Baud O, Schwendimann L, Keller M, Spedding M, Lelièvre V, Gressens P (2006) Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage. Br J Pharmacol 148:442-451
    • (2006) Br J Pharmacol , vol.148 , pp. 442-451
    • Shouman, B.1    Fontaine, R.H.2    Baud, O.3    Schwendimann, L.4    Keller, M.5    Spedding, M.6    Lelièvre, V.7    Gressens, P.8
  • 22
    • 0034613209 scopus 로고    scopus 로고
    • 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-alpha production in murine macrophages, and in mice
    • 11011050 10.1016/S0014-2999(00)00653-1 1:CAS:528:DC%2BD3cXmslOitbg%3D
    • Gallily R, Breuer A, Mechoulam R (2000) 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-alpha production in murine macrophages, and in mice. Eur J Pharmacol 406:R5-R7
    • (2000) Eur J Pharmacol , vol.406
    • Gallily, R.1    Breuer, A.2    Mechoulam, R.3
  • 23
    • 0042572380 scopus 로고    scopus 로고
    • Fatty acid amide hydrolase: An emerging therapeutic target in the endocannabinoid system
    • 12941421 10.1016/S1367-5931(03)00079-6 1:CAS:528:DC%2BD3sXmslemsr0%3D
    • Cravatt BF, Lichtman AH (2003) Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system. Curr Opin Chem Biol 7:469-475
    • (2003) Curr Opin Chem Biol , vol.7 , pp. 469-475
    • Cravatt, B.F.1    Lichtman, A.H.2
  • 25
    • 76449100329 scopus 로고    scopus 로고
    • Lepidium meyenii (Maca): A plant from the highlands of Peru-from tradition to science
    • 20090350 10.1159/000264618
    • Gonzales GF, Gonzales C, Gonzales-Castaneda C (2009) Lepidium meyenii (Maca): a plant from the highlands of Peru-from tradition to science. Forsch Komplementmed 16:373-380
    • (2009) Forsch Komplementmed , vol.16 , pp. 373-380
    • Gonzales, G.F.1    Gonzales, C.2    Gonzales-Castaneda, C.3
  • 26
    • 0037116415 scopus 로고    scopus 로고
    • Constituents of Lepidium meyenii 'Maca'
    • 10.1016/S0031-9422(01)00395-8 1:CAS:528:DC%2BD3MXpt1aitbk%3D
    • Muhammad I, Zhao J, Dunbar DC, Khan IA (2002) Constituents of Lepidium meyenii 'Maca'. Phytochem 59:105-110
    • (2002) Phytochem , vol.59 , pp. 105-110
    • Muhammad, I.1    Zhao, J.2    Dunbar, D.C.3    Khan, I.A.4
  • 27
  • 30
    • 59449101653 scopus 로고    scopus 로고
    • CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay
    • 18855964 10.1002/cbic.200800428 1:CAS:528:DC%2BD1cXhsVCjsbfL
    • Muccioli GG, Labar G, Lambert DM (2008) CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay. ChemBioChem 9:2704-2710
    • (2008) ChemBioChem , vol.9 , pp. 2704-2710
    • Muccioli, G.G.1    Labar, G.2    Lambert, D.M.3
  • 31
    • 80051509102 scopus 로고    scopus 로고
    • Mechanism of inhibition of fatty acid amide hydrolase by sulfonamide-containing benzothiazoles: Long residence time derived from increased kinetic barrier and not exclusively from thermodynamic potency
    • 21728345 10.1021/bi200552p 1:CAS:528:DC%2BC3MXpt1Cjsbc%3D
    • Tian G, Paschetto KA, Gharahdaghi F, Gordon E, Wilkins DE, Luo X, Scott CW (2011) Mechanism of inhibition of fatty acid amide hydrolase by sulfonamide-containing benzothiazoles: long residence time derived from increased kinetic barrier and not exclusively from thermodynamic potency. Biochemistry 50:6867-6878
    • (2011) Biochemistry , vol.50 , pp. 6867-6878
    • Tian, G.1    Paschetto, K.A.2    Gharahdaghi, F.3    Gordon, E.4    Wilkins, D.E.5    Luo, X.6    Scott, C.W.7
  • 32
    • 80052029740 scopus 로고    scopus 로고
    • Biochemical characterization and in vitro activity of AZ513, a noncovalent, reversible, and noncompetitive inhibitor of fatty acid amide hydrolase
    • 21645511 10.1016/j.ejphar.2011.05.052 1:CAS:528:DC%2BC3MXhtVGlt7bK
    • Scott CW, Tian G, Yu XH, Paschetto KA, Wilkins DE, Meury L, Cao CQ, Varnes J, Edwards PD (2011) Biochemical characterization and in vitro activity of AZ513, a noncovalent, reversible, and noncompetitive inhibitor of fatty acid amide hydrolase. Eur J Pharmacol 667:74-79
    • (2011) Eur J Pharmacol , vol.667 , pp. 74-79
    • Scott, C.W.1    Tian, G.2    Yu, X.H.3    Paschetto, K.A.4    Wilkins, D.E.5    Meury, L.6    Cao, C.Q.7    Varnes, J.8    Edwards, P.D.9
  • 34
    • 84978087512 scopus 로고    scopus 로고
    • In vitro screening of reversible and time-dependent inhibition on CYP3A by TM208 and TM209 in rat liver microsomes
    • 1:CAS:528:DC%2BC38XhsVyns7nJ
    • Ning M, Li L, Li J, Li Z, Li R, Zhou T, Lu W (2012) In vitro screening of reversible and time-dependent inhibition on CYP3A by TM208 and TM209 in rat liver microsomes. Acta Pharm Sin B 2:181-187
    • (2012) Acta Pharm Sin B , vol.2 , pp. 181-187
    • Ning, M.1    Li, L.2    Li, J.3    Li, Z.4    Li, R.5    Zhou, T.6    Lu, W.7
  • 38
    • 84885300643 scopus 로고    scopus 로고
    • Enzyme kinetics, inhibition, and regulation
    • Chapter 12 Wiley, New York
    • Voet D, Voet J, Pratt C (2008) Chapter 12. Enzyme kinetics, inhibition, and regulation. In: Principles of biochemistry, Wiley, New York
    • (2008) Principles of Biochemistry
    • Voet, D.1    Voet, J.2    Pratt, C.3
  • 39
    • 28244445935 scopus 로고    scopus 로고
    • Analysis of macamides in samples of Maca (Lepidium meyenii) by HPLC-UV-MS/MS
    • 16315492 10.1002/pca.871 1:CAS:528:DC%2BD2MXht1ygt77P
    • McCollom MM, Villinski JR, McPhail KL, Craker LE, Gafner S (2005) Analysis of macamides in samples of Maca (Lepidium meyenii) by HPLC-UV-MS/MS. Phytochem Anal 16:463-469
    • (2005) Phytochem Anal , vol.16 , pp. 463-469
    • McCollom, M.M.1    Villinski, J.R.2    McPhail, K.L.3    Craker, L.E.4    Gafner, S.5
  • 40
    • 74549185125 scopus 로고    scopus 로고
    • FAAH and MAGL inhibitors: Therapeutic opportunities from regulating endocannabinoid levels
    • 20047159 1:CAS:528:DC%2BC3cXnt1Kgsbo%3D
    • Petrosino S, Di Marzo V (2010) FAAH and MAGL inhibitors: therapeutic opportunities from regulating endocannabinoid levels. Curr Opin Investig Drugs 11:51-62
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 51-62
    • Petrosino, S.1    Di Marzo, V.2
  • 41
    • 0022405968 scopus 로고
    • Arachidonic acid derivatives as mediators of asthma
    • 3926852 10.1016/0091-6749(85)90639-6 1:CAS:528:DyaL2MXltVaktbo%3D
    • Lewis RA, Robin JL (1985) Arachidonic acid derivatives as mediators of asthma. J Allergy Clin Immunol 76:259-264
    • (1985) J Allergy Clin Immunol , vol.76 , pp. 259-264
    • Lewis, R.A.1    Robin, J.L.2
  • 42
    • 0022407335 scopus 로고
    • Proinflammatory properties of unsaturated fatty acids and their monohydroxy metabolites
    • 2997846 1:CAS:528:DyaL2MXmtFaltb8%3D
    • Cunningham FM, Woollard PM, Camp RD (1985) Proinflammatory properties of unsaturated fatty acids and their monohydroxy metabolites. Prostaglandins 30:497-509
    • (1985) Prostaglandins , vol.30 , pp. 497-509
    • Cunningham, F.M.1    Woollard, P.M.2    Camp, R.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.