Analysis of the action of gymnodimine-A and 13-desmethyl spirolide C on the mouse neuromuscular system invivo

Toxicon

Volumn 75, Issue , 2013, Pages 27-34

  Marrouchi, Riadh ^a,b   Rome, Guillaume ^a   Kharrat, Riadh ^b   Molgó, Jordi ^a   Benoit, Evelyne ^a  

^a CNRS   (France)

^b PASTEUR INSTITUTE OF TUNIS   (Tunisia)

Author keywords

13 Desmethyl spirolide C; Cyclic imine toxins; Gymnodimine A; Invivo studies; Mouse neuromuscular excitability; Nicotinic acetylcholine receptors

Indexed keywords

13 DESMETHYL SPIROLIDE C; GYMNODIMINE A; MARINE TOXIN; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; COMPOUND MUSCLE ACTION POTENTIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTRICAL POTENTIAL PARAMETERS; FEMALE; IN VIVO STUDY; MINIMALLY INVASIVE PROCEDURE; MOTOR NERVE; MOUSE; NERVE EXCITABILITY; NERVE STIMULATION; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROMUSCULAR FUNCTION; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING; TOXICOKINETICS; TOXIN ANALYSIS; TOXIN STRUCTURE;

ALEXANDRIUM; DINOPHYCEAE; KARENIA SELLIFORMIS; MUS;

13-DESMETHYL SPIROLIDE C; CYCLIC IMINE TOXINS; GYMNODIMINE-A; IN VIVO STUDIES; MOUSE NEUROMUSCULAR EXCITABILITY; NICOTINIC ACETYLCHOLINE RECEPTORS;

ACTION POTENTIALS; ANIMALS; DINOFLAGELLIDA; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGICAL PHENOMENA; FEMALE; HETEROCYCLIC COMPOUNDS, 3-RING; HYDROCARBONS, CYCLIC; IMINES; MARINE TOXINS; MICE; MOTOR NEURONS; MUSCLE, SKELETAL; NEUROMUSCULAR AGENTS; NEUROMUSCULAR JUNCTION; RECEPTORS, NICOTINIC; SPIRO COMPOUNDS;

EID: 84885303213     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2013.08.050     Document Type: Article

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