High-performance liquid chromatographic method for the determination of dasatinib in rabbit plasma using fluorescence detection and its application to a pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 939, Issue , 2013, Pages 73-79

  Kassem, Mohammed G ^a   Ezzeldin, Essam ^a   Korashy, Hesham M ^a   Mostafa, Gamal A E ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Dasatinib; HPLC; Method of validation; Pharmacokinetic study; Rabbit plasma

Indexed keywords

DASATINIB; HPLC; METHOD OF VALIDATION; PHARMACOKINETIC STUDIES; RABBIT PLASMAS;

AMINO ACIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; PLASMAS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ACEBUTOLOL; ATENOLOL; CIPROFLOXACIN; DASATINIB; ENROFLOXACIN; GEFITINIB; IMATINIB; LOMEFLOXACIN; MONTELUKAST; PROPRANOLOL;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG BINDING; DRUG DETERMINATION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STABILITY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID LIQUID EXTRACTION; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PH; PRIORITY JOURNAL; QUALITY CONTROL; RABBIT; STANDARD; SUPERNATANT; TIME TO MAXIMUM PLASMA CONCENTRATION;

DASATINIB; HPLC; METHOD OF VALIDATION; PHARMACOKINETIC STUDY; RABBIT PLASMA;

ACETATES; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; LIMIT OF DETECTION; LINEAR MODELS; MALE; PYRIMIDINES; QUINOLINES; RABBITS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, FLUORESCENCE; THIAZOLES;

EID: 84885225775     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.09.012     Document Type: Article

References (24)

1. Hubbard S.R., Till J.H. Annu. Rev. Biochem. 2000, 69:373.
2. Lombardo L.J., Lee F.Y., Chen P., Norris D., Barrish J.C., Behnia K., Castaneda S., Cornelius L.A., Das J., Doweyko A.M., Fairchild C., Hunt J.T., Inigo I., Johnston K., Kamath A., Kan D., Klei H., Marathe P., Pang S., Peterson R., Pitt S., Schieven G.L., Schmidt R.J., Tokarski J., Wen M.L., Wityak J., Borzilleri R.M. J. Med. Chem. 2004, 47:6658.
3. Shah N.P., Tran C., Lee F.Y., Chen P., Norris D., Sawyers C.L. Science 2004, 305:399.
4. Tokarski J.S., Newitt J.A., Chang C.Y., Cheng J.D., Wittekind M., Kiefer S.E., Kish K., Lee F.Y., Borzillerri R., Lombardo L.J., Xie D., Zhang Y., Klei H.E. Cancer Res. 2006, 66:5790.
5. Talpaz M., Shah N.P., Kantarjian H., Donato N., Nicoll J., Paquette R., Cortes J., O'Brien S., Nicaise C., Bleickardt E., Blackwood-Chirchir M.A., Iyer V., Chen T.T., Huang F., Decillis A.P., Sawyers C.L. N. Engl. J. Med. 2006, 354:2531.
6. Frame M.C. Src in cancer: deregulation and consequences for cell behavior. Biochim. Biophys. Acta (BBA) 2002, 1602:114-130.
7. Coluccia A.M., Cirulli T., Neri P., Mangieri D., Colanardi M.C., Gnoni A., Di Renzo N., Dammacco F., Tassone P., Ribatti D., Gambacorti-Passerini C., Vacca A. Blood 2008, 112:1346.
8. Miller A.A., Pang H., Hodgson L., Ramnath N., Otterson G.A., Kelley M.J., Kratzke R.A., Vokes E.E. J. Thorac. Oncol. 2010, 5:380.
9. Luo F.R., Barrett Y.C., Yang Z., Camuso A., McGlinchey K., Wen M.L., Smykla R., Fager K., Wild R., Palme H., Galbraith S. Cancer Chemother. Pharmacol. 2008, 62:1065.
10. Pirro E., De Francia S., De Martino F., Fava C., Ulisciani S., Cambrin G.R., Racca S., Saglio G., Di Carlo F. J. Chromatogr. Sci. 2011, 49:753.
11. Dziadosz M., Lessig R., Bartels H. HPLC-DAD protein kinase inhibitor analysis in human serum. J. Chromatogr. B 2012, 893-894:77-81.
12. Birch M., Morgan P.E., Handley S., Ho A., Ireland R., Flanagan R.J. Biomed. Chromatogr.: BMC 2013, 27:335-342.
13. D'Avolio A., Simiele M., De Francia S., Ariaudo A., Baietto L., Cusato J., Fava C., Saglio G., Di Carlo F., Di Perri G. J. Pharm. Biomed. Anal. 2012, 59:109-116.
14. Kralj E., Trontelj J., Pajic T., Kristl A. J. Chromatogr. B 2012, 903:150.
15. Furlong M.T., Agrawal S., Hawthorne D., Lago M., Unger S., Krueger L., Stouffer B. J. Pharm. Biomed. Anal. 2012, 58:130.
16. Bouchet S., Chauzit E., Ducint D., Castaing N., Canal-Raffin M., Moore N., Titier K., Molimard M. Clin. Chim. Acta 2011, 412:1060.
17. Roche S., McMahon G., Clynes M., O'Connor R. J. Chromatogr. B 2009, 877:3982.
18. De Francia S., D'Avolio A., De Martino F., Pirro E., Baietto L., Siccardi M., Simiele M., Racca S., Saglio G., Di Carlo F., Di Perri G. J. Chromatogr. B 2009, 877:1721.
19. Micova K., Friedecky D., Faber E., Adam T. Talanta 2012, 93:307-313.
20. Guidance for Industry: Bioanalytical Method Validation and Industry, US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), Rockville, MD 20857, USA 2001.
21. Luo F.R., Yang Z., Camuso A., Smykla R., McGlinchey K., Fager K., Flefleh C., Castaneda S., Inigo I., Kan D., Wen M.L., Kramer R., Blackwood-Chirchir A., Lee F.Y. Clin. Cancer Res. 2006, 12:7180-7186.
22. ICH March Q2B Validation of Analytical Procedures: Methodology. Proceeding of the International conference on Harmonization 1996.
23. Miller J.N., Miller J.C. Statistics and Chemometrics for Analytical Chemistry 2005, Tottenham, England. 5th ed.
24. Shabir G.A. J. Chromatogr. A 2003, 987:57.