Oral sapropterin augments reflex vasoconstriction in aged human skin through noradrenergic mechanisms

Journal of Applied Physiology

Volumn 115, Issue 7, 2013, Pages 1025-1031

  Stanhewicz, Anna E ^a   Alexander, Lacy M ^a,b   Kenney, W Larry ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b 113 Noll Laboratory   (United States)

Author keywords

Aging; Skin blood flow; Vasoconstriction

Indexed keywords

5,6,7,8-TETRAHYDROBIOPTERIN; BIOPTERIN; DRUG DERIVATIVE; NORADRENALIN; PROPRANOLOL; TETRAHYDROBIOPTERIN; TYRAMINE;

AGED; AGING; ARTERIAL PRESSURE; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; CUTANEOUS PARAMETERS; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HUMAN; MALE; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; REFLEX; SKIN; SKIN BLOOD FLOW; SKIN TEMPERATURE; VASCULARIZATION; VASOCONSTRICTION;

AGING; SKIN BLOOD FLOW; VASOCONSTRICTION;

AGED; AGING; ARTERIAL PRESSURE; BIOPTERIN; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; NOREPINEPHRINE; PROPRANOLOL; REFLEX; SKIN; SKIN AGING; SKIN TEMPERATURE; TYRAMINE; VASOCONSTRICTION;

EID: 84885216614     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00626.2013     Document Type: Article

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