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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 21, 2013, Pages 6025-6028

Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs

(8) Guerra Bubb, Jennifer M a Bowers, Albert A a Smith, William B d Paranal, Ronald d Estiu, Guillermina c Wiest, Olaf c Bradner, James E d Williams, Robert M a,b

a Veterinary Dentistry and Oral Surgery (United States)

b UNIVERSITY OF COLORADO CANCER CENTER (United States)

c UNIVERSITY OF NOTRE DAME (United States)

d DANA FARBER CANCER INSTITUTE (United States)

Author keywords

Conformation; HDAC; Isostere; Largazole; Oxazole

Indexed keywords

HISTONE DEACETYLASE; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE 7; HISTONE DEACETYLASE 8; HISTONE DEACETYLASE INHIBITOR; LARGAZOLE; OXAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; MOLECULAR DYNAMICS;

CONFORMATION; HDAC; ISOSTERE; LARGAZOLE; OXAZOLE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DEPSIPEPTIDES; HISTONE DEACETYLASE INHIBITORS; HUMANS; MOLECULAR DOCKING SIMULATION; NEOPLASMS; OXAZOLES; THIAZOLES;

EID: 84885189972 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.06.012 Document Type: Article

Times cited : (30)

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