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Volumn 32, Issue 40, 2013, Pages 4778-4788

The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery

Author keywords

cell cycle; checkpoint; ionizing radiation

Indexed keywords

7 HYDROXYSTAUROSPORINE; ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CDK1 INHIBITORY KINASE MYT1; CHECKPOINT KINASE 1 INHIBITOR; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; DNA; MK 1775; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASE INHIBITOR; RO 3306; UNCLASSIFIED DRUG; WEE1 INHIBITOR; WEE1 PROTEIN;

EID: 84885179495     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.504     Document Type: Article
Times cited : (56)

References (36)
  • 1
    • 17044429330 scopus 로고    scopus 로고
    • A roller coaster ride with the mitotic cyclins
    • Fung TK, Poon RYC. A roller coaster ride with the mitotic cyclins. Semin Cell Dev Biol 2005; 16: 335-342.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 335-342
    • Fung, T.K.1    Poon, R.Y.C.2
  • 2
    • 0030803797 scopus 로고    scopus 로고
    • Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity
    • Booher RN, Holman PS, Fattaey A. Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity. J Biol Chem 1997; 272: 22300-22306.
    • (1997) J Biol Chem , vol.272 , pp. 22300-22306
    • Booher, R.N.1    Holman, P.S.2    Fattaey, A.3
  • 3
    • 0026616796 scopus 로고
    • Inactivation of the p34cdc2-cyclin b complex by the human WEE1 tyrosine kinase
    • Parker LL, Piwnica-Worms H. Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. Science 1992; 257: 1955-1957.
    • (1992) Science , vol.257 , pp. 1955-1957
    • Parker, L.L.1    Piwnica-Worms, H.2
  • 4
    • 4444321565 scopus 로고    scopus 로고
    • Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells
    • Van Vugt MA, Bras A, Medema RH. Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells. Mol Cell 2004; 15: 799-811.
    • (2004) Mol Cell , vol.15 , pp. 799-811
    • Van Vugt, M.A.1    Bras, A.2    Medema, R.H.3
  • 5
    • 23844525856 scopus 로고    scopus 로고
    • Cyclin-dependent kinase (CDK) phosphorylation de stabilizes somatic Wee1 via multiple pathways
    • Watanabe N, Arai H, Iwasaki J, Shiina M, Ogata K, Hunter T et al. Cyclin-dependent kinase (CDK) phosphorylation de stabilizes somatic Wee1 via multiple pathways. Proc Natl Acad Sci USA 2005; 102: 11663-11668.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 11663-11668
    • Watanabe, N.1    Arai, H.2    Iwasaki, J.3    Shiina, M.4    Ogata, K.5    Hunter, T.6
  • 7
    • 20744437413 scopus 로고    scopus 로고
    • Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition
    • Katayama K, Fujita N, Tsuruo T. Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition. Mol Cell Biol 2005; 25: 5725-5737.
    • (2005) Mol Cell Biol , vol.25 , pp. 5725-5737
    • Katayama, K.1    Fujita, N.2    Tsuruo, T.3
  • 8
    • 0032705499 scopus 로고    scopus 로고
    • The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression
    • Wells NJ, Watanabe N, Tokusumi T, Jiang W, Verdecia MA, Hunter T. The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression. J Cell Sci 1999; 112: 3361-3371.
    • (1999) J Cell Sci , vol.112 , pp. 3361-3371
    • Wells, N.J.1    Watanabe, N.2    Tokusumi, T.3    Jiang, W.4    Verdecia, M.A.5    Hunter, T.6
  • 9
    • 0038492408 scopus 로고    scopus 로고
    • Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate
    • Nakajima H, Toyoshima-Morimoto F, Taniguchi E, Nishida E. Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate. J Biol Chem 2003; 278: 25277-25280.
    • (2003) J Biol Chem , vol.278 , pp. 25277-25280
    • Nakajima, H.1    Toyoshima-Morimoto, F.2    Taniguchi, E.3    Nishida, E.4
  • 10
    • 10344246106 scopus 로고    scopus 로고
    • Drosophila Wee1 kinase regulates Cdk1 and mitotic entry during embryogenesis
    • Stumpff J, Duncan T, Homola E, Campbell SD, Su TT. Drosophila Wee1 kinase regulates Cdk1 and mitotic entry during embryogenesis. Curr Biol 2004; 14: 2143-2148.
    • (2004) Curr Biol , vol.14 , pp. 2143-2148
    • Stumpff, J.1    Duncan, T.2    Homola, E.3    Campbell, S.D.4    Su, T.T.5
  • 12
    • 0034141887 scopus 로고    scopus 로고
    • Absence of Wee1 ensures the meiotic cell cycle in Xenopus oocytes
    • Nakajo N, Yoshitome S, Iwashita J, Iida M, Uto K, Ueno S et al. Absence of Wee1 ensures the meiotic cell cycle in Xenopus oocytes. Genes Dev 2000; 14: 328-338.
    • (2000) Genes Dev , vol.14 , pp. 328-338
    • Nakajo, N.1    Yoshitome, S.2    Iwashita, J.3    Iida, M.4    Uto, K.5    Ueno, S.6
  • 13
    • 53949102028 scopus 로고    scopus 로고
    • Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation
    • Ruiz EJ, Hunt T, Nebreda AR. Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation. Mol Cell 2008; 32: 210-220.
    • (2008) Mol Cell , vol.32 , pp. 210-220
    • Ruiz, E.J.1    Hunt, T.2    Nebreda, A.R.3
  • 14
    • 0036174009 scopus 로고    scopus 로고
    • Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition
    • Okumura E, Fukuhara T, Yoshida H, Hanada Si S, Kozutsumi R, Mori M et al. Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition. Nat Cell Biol 2002; 4: 111-116.
    • (2002) Nat Cell Biol , vol.4 , pp. 111-116
    • Okumura, E.1    Fukuhara, T.2    Yoshida, H.3    Hanada Si, S.4    Kozutsumi, R.5    Mori, M.6
  • 15
    • 42649131088 scopus 로고    scopus 로고
    • The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability
    • Chen Y, Poon RYC. The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability. Front Biosci 2008; 13: 5016-5029.
    • (2008) Front Biosci , vol.13 , pp. 5016-5029
    • Chen, Y.1    Poon, R.Y.C..2
  • 16
    • 0029825066 scopus 로고    scopus 로고
    • Role of inhibitory CDC2 phosphorylation in radiationinduced G2 arrest in human cells
    • Jin P, Gu Y, Morgan DO. Role of inhibitory CDC2 phosphorylation in radiationinduced G2 arrest in human cells. J Cell Biol 1996; 134: 963-970.
    • (1996) J Cell Biol , vol.134 , pp. 963-970
    • Jin, P.1    Gu, Y.2    Morgan, D.O.3
  • 17
    • 0031035528 scopus 로고    scopus 로고
    • Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation
    • O?Connell MJ, Raleigh JM, Verkade HM, Nurse P. Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J 1997; 16: 545-554.
    • (1997) EMBO J , vol.16 , pp. 545-554
    • Oconnell, M.J.1    Raleigh, J.M.2    Verkade, H.M.3    Nurse, P.4
  • 18
    • 18344366048 scopus 로고    scopus 로고
    • Getting in and out of mitosis with Polo-like kinase-1
    • Van Vugt MA, Medema RH. Getting in and out of mitosis with Polo-like kinase-1. Oncogene 2005; 24: 2844-2859.
    • (2005) Oncogene , vol.24 , pp. 2844-2859
    • Van Vugt Ma1    Medema, R.H.2
  • 19
    • 33745001764 scopus 로고    scopus 로고
    • Cdc25: Mechanisms of checkpoint inhibition and recovery
    • Karlsson-Rosenthal C, Millar JB. Cdc25: Mechanisms of checkpoint inhibition and recovery. Trends Cell Biol 2006; 16: 285-292.
    • (2006) Trends Cell Biol , vol.16 , pp. 285-292
    • Karlsson-Rosenthal, C.1    Millar, J.B.2
  • 20
    • 79955998513 scopus 로고    scopus 로고
    • Determinants of mitotic catastrophe on abrogation of the G2 DNA damage checkpoint by UCN-01
    • On KF, Chen Y, Ma HT, Chow JP, Poon RYC. Determinants of mitotic catastrophe on abrogation of the G2 DNA damage checkpoint by UCN-01. Mol Cancer Ther 2011; 10: 784-794.
    • (2011) Mol Cancer Ther , vol.10 , pp. 784-794
    • On, K.F.1    Chen, Y.2    Ma, H.T.3    Chow, J.P.4    Ryc, P.5
  • 21
    • 67649710471 scopus 로고    scopus 로고
    • Discovery of gene expression-based pharmacodynamic biomarker for a p53 context-specific anti-tumor drug Wee1 inhibitor
    • Mizuarai S, Yamanaka K, Itadani H, Arai T, Nishibata T, Hirai H et al. Discovery of gene expression-based pharmacodynamic biomarker for a p53 context-specific anti-tumor drug Wee1 inhibitor. Mol Cancer 2009; 8: 34.
    • (2009) Mol Cancer , vol.8 , pp. 34
    • Mizuarai, S.1    Yamanaka, K.2    Itadani, H.3    Arai, T.4    Nishibata, T.5    Hirai, H.6
  • 22
    • 79953793743 scopus 로고    scopus 로고
    • Inhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit
    • Chow JP, Poon RYC, Ma HT. Inhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit. Mol Cell Biol 2011; 31: 1478-1491.
    • (2011) Mol Cell Biol , vol.31 , pp. 1478-1491
    • Chow, J.P.1    Ryc, P.2    Ma, H.T.3
  • 23
    • 0026006392 scopus 로고
    • Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: Evidence for a double block to p34cdc2 kinase activation in vertebrates
    • Krek W, Nigg EA. Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: Evidence for a double block to p34cdc2 kinase activation in vertebrates. EMBO J 1991; 10: 3331-3341.
    • (1991) EMBO J , vol.10 , pp. 3331-3341
    • Krek, W.1    Nigg, E.A.2
  • 24
    • 16544392882 scopus 로고    scopus 로고
    • Knockdown of chk1 wee1 and myt1 by RNA interference abrogates G2 checkpoint and induces apoptosis
    • Wang Y, de cker SJ, Sebolt-Leopold J. Knockdown of Chk1, Wee1 and Myt1 by RNA interference abrogates G2 checkpoint and induces apoptosis. Cancer Biol Ther 2004; 3: 305-313.
    • (2004) Cancer Biol Ther , vol.3 , pp. 305-313
    • Wang, Y.1    Decker, S.J.2    Sebolt-Leopold, J.3
  • 25
    • 0039596852 scopus 로고    scopus 로고
    • De gradation of cyclin A does not require its phosphorylation by CDC2 and cyclin-dependent kinase 2
    • Yam CH, Siu WY, Lau A, Poon RYC. de gradation of cyclin A does not require its phosphorylation by CDC2 and cyclin-dependent kinase 2. J Biol Chem 2000; 275: 3158-3167.
    • (2000) J Biol Chem , vol.275 , pp. 3158-3167
    • Yam, C.H.1    Siu, W.Y.2    Lau, A.3    Poon, R.Y.C.4
  • 26
    • 45749123913 scopus 로고    scopus 로고
    • CDK1 inhibitors antagonize the immediate apoptosis triggered by spindle disruption but promote apoptosis following the subsequent rereplication and abnormal mitosis
    • Chan YW, Ma HT, Wong W, Ho CC, On KF, Poon RYC. CDK1 inhibitors antagonize the immediate apoptosis triggered by spindle disruption but promote apoptosis following the subsequent rereplication and abnormal mitosis. Cell Cycle 2008; 7: 1449-1461.
    • (2008) Cell Cycle , vol.7 , pp. 1449-1461
    • Chan, Y.W.1    Ma, H.T.2    Wong, W.3    Ho, C.C.4    On, K.F.5    Poon, R.Y.C..6
  • 27
    • 58249124609 scopus 로고    scopus 로고
    • Generation of an indestructible cyclin B1 by caspase-6-dependent cleavage during mitotic catastrophe
    • Chan YW, Chen Y, Poon RYC. Generation of an indestructible cyclin B1 by caspase-6-dependent cleavage during mitotic catastrophe. Oncogene 2009; 28: 170-183.
    • (2009) Oncogene , vol.28 , pp. 170-183
    • Chan, Y.W.1    Chen, Y.2    Poon, R.Y.C..3
  • 28
    • 0000507213 scopus 로고    scopus 로고
    • Differential responses of proliferating versus quiescent cells to adriamycin
    • Siu WY, Arooz T, Poon RYC. Differential responses of proliferating versus quiescent cells to adriamycin. Exp Cell Res 1999; 250: 131-141.
    • (1999) Exp Cell Res , vol.250 , pp. 131-141
    • Siu, W.Y.1    Arooz, T.2    Poon, R.Y.C..3
  • 29
    • 84861176263 scopus 로고    scopus 로고
    • Inhibition of Eg5 acts synergistically with checkpoint abrogation in promoting mitotic catastrophe
    • Chen Y, Chow JP, Poon RY. Inhibition of Eg5 acts synergistically with checkpoint abrogation in promoting mitotic catastrophe. Mol Cancer Res 2012; 10: 626-635.
    • (2012) Mol Cancer Res , vol.10 , pp. 626-635
    • Chen, Y.1    Chow, J.P.2    Poon, R.Y.3
  • 30
    • 0031053117 scopus 로고    scopus 로고
    • The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex
    • Liu F, Stanton JJ, Wu Z, Piwnica-Worms H. The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex. Mol Cell Biol 1997; 17: 571-583.
    • (1997) Mol Cell Biol , vol.17 , pp. 571-583
    • Liu, F.1    Stanton, J.J.2    Wu, Z.3    Piwnica-Worms, H.4
  • 31
    • 71949109169 scopus 로고    scopus 로고
    • Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosis
    • Ma HT, Tsang YH, Marxer M, Poon RYC. Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosis. Mol Cell Biol 2009; 29: 6500-6514.
    • (2009) Mol Cell Biol , vol.29 , pp. 6500-6514
    • Ma, H.T.1    Tsang, Y.H.2    Marxer, M.3    Poon, R.Y.C..4
  • 32
    • 0142135133 scopus 로고    scopus 로고
    • Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints
    • Chow JP, Siu WY, Ho HT, Ma KH, Ho CC, Poon RYC. Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints. J Biol Chem 2003; 278: 40815-40828.
    • (2003) J Biol Chem , vol.278 , pp. 40815-40828
    • Chow, J.P.1    Siu, W.Y.2    Ho, H.T.3    Ma, K.H.4    Ho, C.C.5    Poon, R.Y.C..6
  • 33
    • 47049109949 scopus 로고    scopus 로고
    • The kinetics of p53 activation versus cyclin e accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint
    • Chan YW, On KF, Chan WM, Wong W, Siu HO, Hau PM et al. The kinetics of p53 activation versus cyclin E accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint. J Biol Chem 2008; 283: 15716-15723.
    • (2008) J Biol Chem , vol.283 , pp. 15716-15723
    • Chan, Y.W.1    On, K.F.2    Chan, W.M.3    Wong, W.4    Siu, H.O.5    Hau, P.M.6
  • 35
    • 0029145975 scopus 로고
    • Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation
    • Poon RYC, Toyoshima H, Hunter T. Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation. Mol Biol Cell 1995; 6: 1197-1213.
    • (1995) Mol Biol Cell , vol.6 , pp. 1197-1213
    • Ryc, P.1    Toyoshima, H.2    Hunter, T.3
  • 36
    • 0024354304 scopus 로고
    • Determination of subcutaneous tumor size in athymic (nude) mice
    • Tomayko MM, Reynolds CP. Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother Pharmacol 1989; 24: 148-154.
    • (1989) Cancer Chemother Pharmacol , vol.24 , pp. 148-154
    • Tomayko, M.M.1    Reynolds, C.P.2


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