Even low physical activity levels improve vascular function in overweight and obese postmenopausal women

Menopause

Volumn 20, Issue 10, 2013, Pages 1036-1042

  Merino, Jordi ^a,b   Ferré, Raimon ^a,b   Girona, Josefa ^a,b   Aguas, Dolors ^c   Cabré, Anna ^a,b   Plana, Núria ^a,b   Vinuesa, Angels ^d,e   Ibarretxe, Daiana ^a,b   Basora, Josep ^d,e   Buixadera, Carme ^a,b   Masana, Lluís ^a,b  

^a HOSPITAL UNIVERSITARI SANT JOAN DE REUS   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c Ajuntament de Reus ^*  (Spain)

^d INSTITUT CATALÀ DE LA SALUT   (Spain)

^e Institut d'Investigació en Atenció Primària Jordi Gol   (Spain)

Author keywords

Asymmetrical dimethylarginine; Oxidative stress; Physical activity; Physical activity intervention; Postmenopause; Small artery endothelial function

Indexed keywords

GLUTATHIONE PEROXIDASE; N(G),N(G) DIMETHYLARGININE; OXIDIZED LOW DENSITY LIPOPROTEIN; SUPEROXIDE DISMUTASE;

ADULT; ARTICLE; BLOOD VESSEL FUNCTION; CLINICAL ASSESSMENT TOOL; DISEASE ASSOCIATION; DISEASE MARKER; ENZYME ACTIVITY; FEMALE; HEART RATE; HEMOLYSATE; HUMAN; HYPOTHESIS; INTRAABDOMINAL FAT; MAJOR CLINICAL STUDY; OBESITY; OXIDATIVE STRESS; PHYSICAL ACTIVITY; POSTMENOPAUSE; SMALL ARTERY REACTIVE HYPEREMIA INDEX; SUBCUTANEOUS FAT;

AGED; ARTERIES; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; ENDOTHELIUM, VASCULAR; EXERCISE; FEMALE; GLUTATHIONE PEROXIDASE; HEART RATE; HUMANS; HYPEREMIA; LIPOPROTEINS, LDL; MIDDLE AGED; OBESITY; OVERWEIGHT; OXIDATIVE STRESS; POSTMENOPAUSE; RISK FACTORS; SUPEROXIDE DISMUTASE;

EID: 84885175461     PISSN: 10723714     EISSN: 15300374     Source Type: Journal    
DOI: 10.1097/GME.0b013e31828501c9     Document Type: Article

References (31)

1. Kones R. Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey. Drug Des Dev Ther 2011;5: 325-380.
2. Mora S, Cook N, Buring JE, et al. Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms. Circulation 2007;116: 2110-2118.
3. Physical activity guidelines for Americans. Okla Nurse 2008;53: 25.
4. Physical Activity Guidelines Advisory Committee report, 2008. To the Secretary of Health and Human Services. Part A: executive summary. Nutr Rev 2009;67: 114-120.
5. Hambrecht R, Fiehn E, Weigl C, et al. Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation 1998;98: 2709-2715.
6. DeSouza CA, Shapiro LF, Clevenger CM, et al. Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Circulation 2000;102: 1351-1357.
7. Newsholme P, Homem De Bittencourt PI, O'Hagan C, De Vito G, Murphy C, Krause MS. Exercise and possible molecular mechanisms of protection from vascular disease and diabetes: the central role of ROS and nitric oxide. Clin Sci (Lond) 2009;118: 341-349.
8. Sibal L, Agarwal SC, Home PD, et al. The role of asymmetric dimethylarginine (ADMA) in endothelial dysfunction and cardiovascular disease. Curr Cardiol Rev 2010;6: 82-90.
9. Pellegrin M, Alonso F, Aubert JF, et al. Swimming prevents vulnerable atherosclerotic plaque development in hypertensive 2-kidney, 1-clip mice by modulating angiotensin II type 1 receptor expression independently from hemodynamic changes. Hypertension 2009;53: 782-789.
10. Gomes VA, Casella-Filho A, Chagas AC, et al. Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome. Nitric Oxide 2008;19: 345-350.
11. Earnest CP, Lavie CJ, Blair SN, et al. Heart rate variability characteristics in sedentary postmenopausal women following six months of exercise training: the DREW study. PLoS One 2008;3:e2288.
12. Castelao JE, Gago-Dominguez M. Risk factors for cardiovascular disease in women: relationship to lipid peroxidation and oxidative stress. Med Hypotheses 2008;71: 39-44.
13. Pierce GL, Eskurza I, Walker AE, et al. Sex-specific effects of habitual aerobic exercise on brachial artery flowYmediated dilation in middle-aged and older adults. Clin Sci (Lond) 2011;120: 13-23.
14. Goel R, Majeed F, Vogel R, et al. Exercise-induced hypertension, endothelial dysfunction, and coronary artery disease in a marathon runner. Am J Cardiol 2007;99: 743-744.
15. Crouch R, Wilson A, Newbury J. A systematic review of the effectiveness of primary health education or intervention programs in improving rural women's knowledge of heart disease risk factors and changing lifestyle behaviours. Int J Evid Based Healthc 2011;9: 236-245.
16. Ferre R, Plana N, Merino J, et al. Effects of therapeutic lifestyle changes on peripheral artery tonometry in patients with abdominal obesity. Nutr Metab Cardiovasc Dis 2011;22: 95-102.
17. Elosua R, Garcia M, Aguilar A, et al. Validation of the Minnesota Leisure Time Physical Activity Questionnaire in Spanish women. Investigators of the MARATDON Group. Med Sci Sports Exerc 2000;32: 1431-1437.
18. Panagiotakos DB, Pitsavos C, Arvaniti F, et al. Adherence to the Mediterranean food pattern predicts the prevalence of hypertension, hypercholesterolemia, diabetes and obesity, among healthy adults; the accuracy of the MedDietScore. Prev Med 2007;44: 335-340.
19. DiClemente CC, Prochaska JO, Fairhurst SK, et al. The process of smoking cessation: an analysis of precontemplation, contemplation, and preparation stages of change. J Consult Clin Psychol 1991;59: 295-304.
20. Hamburg NM, Keyes MJ, Larson MG, et al. Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study. Circulation 2008;117: 2467-2474.
21. Vlachos IS, Hatziioannou A, Perelas A, et al. Sonographic assessment of regional adiposity. AJR Am J Roentgenol 2007;189: 1545-1553.
22. Pansini F, Cervellati C, Guariento A, et al. Oxidative stress, body fat composition, and endocrine status in pre- and postmenopausal women. Menopause 2008;15: 112-118.
23. Wycherley TP, Brinkworth GD, Noakes M, et al. Effect of caloric restriction with and without exercise training on oxidative stress and endothelial function in obese subjects with type 2 diabetes. Diabetes Obes Metab 2008;10: 1062-1073.
24. Bemelmans RH, van der Graaf Y, Nathoe HM, et al. Increased visceral adipose tissue is associated with increased resting heart rate in patients with manifest vascular disease. Obesity (Silver Spring) 2012;20: 834-841.
25. Pou KM, Massaro JM, Hoffmann U, et al. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation 2007;116: 1234-1241.
26. Lazaro I, Ferre R, Plana N, et al. Lifestyle changes lower FABP4 plasma concentration in patients with cardiovascular risk. Rev Esp Cardiol 2012;65: 152-157.
27. Schlager O, Giurgea A, Schuhfried O, et al. Exercise training increases endothelial progenitor cells and decreases asymmetric dimethylarginine in peripheral arterial disease: a randomized controlled trial. Atherosclerosis 2011;217: 240-248.
28. Custodis F, Baumhakel M, Schlimmer N, et al. Heart rate reduction by ivabradine reduces oxidative stress, improves endothelial function, and prevents atherosclerosis in apolipoprotein EYdeficient mice. Circulation 2008;117: 2377-2387.
29. Drouin A, Gendron ME, Thorin E, et al. Chronic heart rate reduction by ivabradine prevents endothelial dysfunction in dyslipidaemic mice. Br J Pharmacol 2008;154: 749-757.
30. Heusch G, Skyschally A, Gres P, et al. Improvement of regional myocardial blood flow and function and reduction of infarct size with ivabradine: protection beyond heart rate reduction. Eur Heart J 2008; 29: 2265-2275.
31. Thorin E, Thorin-Trescases N. Vascular endothelial ageing, heartbeat after heartbeat. Cardiovasc Res 2009;84: 24-32.