Chronic heart rate reduction by ivabradine prevents endothelial dysfunction in dyslipidaemic mice

British Journal of Pharmacology

Volumn 154, Issue 4, 2008, Pages 749-757

  Drouin, A ^a   Gendron, M E ^a   Thorin, E ^a   Gillis, M A ^a   Mahlberg Gaudin, F ^b   Tardif, J C ^a  

^a MONTREAL HEART INSTITUTE   (Canada)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Cardiac dysfunction; Hypercholesterolaemia; Metoprolol; Telemetry; Vasodilatation and acetylcholine

Indexed keywords

ACETYLCHOLINE; ACETYLCYSTEINE; CATALASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROGEN PEROXIDE; INDOMETACIN; ISOFLURANE; IVABRADINE; METOPROLOL; N(G) NITROARGININE; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ARTERY; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG EFFECT; DYSLIPIDEMIA; ELECTROCARDIOGRAM; ENDOTHELIAL DYSFUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART RATE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RENAL ARTERY; TELEMETRY; TREATMENT OUTCOME; VASODILATATION;

ACETYLCHOLINE; ANIMALS; APOLIPOPROTEIN B-100; BENZAZEPINES; BLOOD PRESSURE; CARDIOTONIC AGENTS; CEREBRAL ARTERIES; DYSLIPIDEMIAS; ENDOTHELIUM, VASCULAR; HEART RATE; MALE; MICE; MICE, INBRED C57BL; RENAL ARTERY; TIME FACTORS; VASODILATION;

EID: 44949127974     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.116     Document Type: Article

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