SPIO-PICsome: Development of a highly sensitive and stealth-capable MRI nano-agent for tumor detection using SPIO-loaded unilamellar polyion complex vesicles (PICsomes)

Journal of Controlled Release

Volumn 169, Issue 3, 2013, Pages 220-227

  Kokuryo, Daisuke ^a   Anraku, Yasutaka ^b   Kishimura, Akihiro ^b   Tanaka, Sayaka ^c   Kano, Mitsunobu R ^c   Kershaw, Jeff ^a   Nishiyama, Nobuhiro ^d   Saga, Tsuneo ^a   Aoki, Ichio ^a   Kataoka, Kazunori ^b,e  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

^d TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

(SPIOs); Drug delivery system; Magnetic resonance imaging (MRI); Polyion complex vesicles (PICsomes); Superparamagnetic iron oxide nanoparticles; Tumor diagnosis

Indexed keywords

BIOCOMPATIBILITY; GRAFTING (CHEMICAL); HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; IRON COMPOUNDS; IRON OXIDES; LIGHT SCATTERING; LIGHT TRANSMISSION; MAGNETIC RESONANCE IMAGING; METAL NANOPARTICLES; NANOMAGNETICS; NANOPARTICLES; POLYETHYLENE GLYCOLS; SELF ASSEMBLY; SUPERPARAMAGNETISM; SYNTHESIS (CHEMICAL); TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

(SPIOS); DRUG DELIVERY SYSTEM; POLYION COMPLEX; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES; TUMOR DIAGNOSIS;

DIAGNOSIS;

AMINO ACID; CYANINE DYE 5; FERUCARBOTRAN; MACROGOL; NANOCARRIER; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE; UNCLASSIFIED DRUG; UNILAMELLAR POLYION COMPLEX VESICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER DIAGNOSIS; COLON CANCER; CONTROLLED STUDY; EARLY DIAGNOSIS; FEMALE; FLUORESCENCE IMAGING; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; TUMOR VOLUME;

EID: 84885171684     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.03.016     Document Type: Article

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