Salicortin-derivatives from Salix pseudo-lasiogyne twigs inhibit adipogenesis in 3T3-L1 cells via modulation of C/EBPα and SREBP1c dependent pathway

Molecules

Volumn 18, Issue 9, 2013, Pages 10484-10496

  Lee, Mina ^a   Lee, Sang Hoon ^a   Kang, Jimmy ^a   Yang, Heejung ^a   Jeong, Eun Ju ^b   Kim, Hong Pyo ^c   Kim, Young Choong ^a   Sung, Sang Hyun ^a  

^a Seoul National University   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Ajou University   (South Korea)

Author keywords

3T3 L1; Adipocyte differentiation; Adipogenesis; C EBP ; Obesity; Salicaceae; Salix pseudo lasiogyne; SREBP1c

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CEBPA PROTEIN, MOUSE; GLUCOSIDE; METHANOL; PLANT EXTRACT; SALICORTIN; SOLVENT; SREBF1 PROTEIN, MOUSE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ADIPOCYTE; ADIPOGENESIS; ANIMAL; ARTICLE; CELL STRAIN 3T3; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; GENE EXPRESSION; GENETICS; IC 50; ISOLATION AND PURIFICATION; METABOLISM; MOUSE; OBESITY; PHYSIOLOGY; PLANT STEM; SOLID PHASE EXTRACTION; WILLOW; 3T3 CELL LINE; DRUG EFFECTS; IC50;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; GLUCOSIDES; INHIBITORY CONCENTRATION 50; METHANOL; MICE; OBESITY; PLANT EXTRACTS; PLANT STEMS; SALIX; SOLID PHASE EXTRACTION; SOLVENTS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84885138734     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules180910484     Document Type: Article

References (37)

1. Abate, N. Obesity and cardiovascular disease. Pathogenetic role of the metabolic syndrome and therapeutic implications. J. Diabetes Complicat. 2000, 14, 154-174.
2. Kopelman, P.G. Obesity as a medical problem. Nature 2000, 404, 635-643. (Pubitemid 30205068)
3. Wadden, T.A. Treatment of obesity by moderate and severe caloric restriction. Results of clinical research trials. Ann. Intern. Med. 1993, 119, 688-693. (Pubitemid 23313690)
4. Nathan, P.J.; O'Neill, B.V.; Napolitano, A.; Bullmore, E.T. Neuropsychiatric adverse effects of centrally acting antiobesity drugs. CNS Neurosci. Ther. 2011, 17, 490-505.
5. Yang, J.Y.; Della-Fera, M.A.; Rayalam, S.; Ambati, S.; Hartzell, D.L.; Park, H.J.; Baile, C.A. Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin. Life Sci. 2008, 82, 1032-1039.
6. Rosen, E.D.; Spiegelman, B.M. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 2006, 444, 847-853. (Pubitemid 46024991)
7. Rayalam, S.; Della-Fera, M.A.; Baile, C.A. Phytochemicals and regulation of the adipocyte life cycle. J. Nutr. Biochem. 2008, 19, 717-726.
8. Du, Q.; Jerz, G.; Shen, L.; Xiu, L.; Winterhalter, P. Isolation and structure determination of a lignan from the bark of Salix alba. Nat. Prod. Res. 2007, 21, 451-454. (Pubitemid 47386420)
9. Freischmidt, A.; Jürgenliemk, G.; Kraus, B.; Okpanyi, S.N.; Müller, J.; Kelber, O.; Weiser, D.; Heilmann, J. Contribution of flavonoids and catechol to the reduction of ICAM-1 expression in endothelial cells by a standardised Willow bark extract. Phytomedicine 2012, 19, 245-252.
10. Li, X.; Liu, Z.; Zhang, X.F.; Wang, L.J.; Zheng, Y.N.; Yuan, C.C.; Sun, G.Z. Isolation and characterization of phenolic compounds from the leaves of Salix matsudana. Molecules 2008, 13, 1530-1537.
11. Alam, M.S.; Kaur, G.; Jabbar, Z.; Javed, K.; Athar, M. Evaluation of antioxidant activity of Salix caprea flowers. Phytother. Res. 2006, 20, 479-483. (Pubitemid 43953402)
12. Sultana, S.; Saleem, M. Salix caprea inhibits skin carcinogenesis in murine skin: Inhibition of oxidative stress, Ornithine decarboxylase activity and DNA synthesis. J. Ethnopharmacol. 2004, 91, 267-276. (Pubitemid 38561125)
13. Han, L.K.; Sumiyoshi, M.; Zhang, J.; Liu, M.X.; Zhang, X.F.; Zheng, Y.N.; Okuda, H.; Kimura, Y. Anti-obesity action of Salix matsudana leaves (Part 1). Anti-obesity action by polyphenols of Salix matsudana in high fat-diet treated rodent animals. Phytother. Res. 2003, 17, 1188-1194. (Pubitemid 38057177)
14. Yang, H.; Lee, S.H.; Sung, S.H.; Kim, J.; Kim, Y.C. Neuroprotective compounds from Salix pseudo-lasiogyne twigs and their anti-amnesic effects on scopolamine-induced memory deficit in mice. Planta Med. 2013, 79, 78-82.
15. Lin, J.; Della-Fera, M.A.; Baile, C.A. Green tea polyphenol epigallocatechin gallate inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes. Obes. Res. 2005, 13, 982-990.
16. Huang, B.; Yuan, H.D.; Kim, D.Y.; Quan H.Y.; Chung, S.H. Cinnamaldehyde prevents adipocyte differentiation and adipogenesis via regulation of peroxisome proliferator-activated receptor-γ (PPARγ) and AMP-activated protein kinase (AMPK) pathways. J. Agric. Food. Chem. 2011, 59, 3666-3673.
17. Paton, C.M.; Ntambi, J.M. Biochemical and physiological function of stearoyl-CoA desaturase. Am. J. Physiol. Endocrinol. MeTable 2009, 297, 28-37.
18. Roncari, D.A.; Lau, D.C.; Kindler, S. Exaggerated replication in culture of adipocyte precursors from massively obese persons. Metabolism 1981, 30, 425-427. (Pubitemid 11099657)
19. Martineau, L.C.; Muhammad, A.; Saleem, A.; Hervé, J.; Harris, C.S.; Arnason, J.T.; Haddad, P.S. Anti-adipogenic activities of Alnus incana and Populus balsamifera bark extracts, part II: bioassay-guided identification of actives salicortin and oregonin. Planta Med. 2010, 76, 1519-1524.
20. Subramanian, B.; Nakeff, A.; Tenney, K.; Crews, P.; Gunatilaka, L.; Valeriote, F. A new paradigm for the development of anticancer agents from natural products. J. Exp. Ther. Oncol. 2006, 5, 195-204. (Pubitemid 43843830)
21. Mahdi, J.G.; Mahdi, A.J.; Mahdi, A.J.; Bowen, I.D. The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential. Cell. Prolif. 2006, 39, 147-155.
22. Lee, M.; Lee, H.H.; Lee, J.K.; Ye, S.K.; Kim, S.H.; Sung, S.H. Anti-adipogenic activity of compounds isolated from Idesia polycarpa on 3T3-L1 cells. Bioorg. Med. Chem. Lett. 2013, 23, 3170-3174.
23. Farmer, S.R. Transcriptional control of adipocyte formation. Cell Metab. 2006, 4, 263-273. (Pubitemid 44430910)
24. Rosen, E.D. The transcriptional basis of adipocyte development. Prostaglandins Leukot. Essent. Fatty Acids 2005, 73, 31-34. (Pubitemid 40826925)
25. Tang, Q.Q.; Lane, M.D. Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation. Genes Dev. 1999, 13, 2231-2241. (Pubitemid 29426728)
26. Cao, Z.; Umek, R.M.; McKnight, S.L. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 1991, 5, 1538-1552. (Pubitemid 21906060)
27. Tang, Q.Q.; Otto, T.C.; Lane, M.D. CCAAT/enhancerbinding protein beta is required for mitotic clonal expansion during adipogenesis. Proc. Natl. Acad. Sci. USA 2003, 100, 850-855. (Pubitemid 36183919)
28. Horton, J.D.; Goldstein, J.L.; Brown, M.S. SREBPs: transcriptional mediators of lipid homeostasis. Cold Spring Harb. Symp. Quant. Biol. 2002, 67, 491-498. (Pubitemid 36775545)
29. Rosen, E.D.; Walkey, C.J.; Puigserver, P.; Spiegelman, B.M. Transcriptional regulation of adipogenesis. Genes Dev. 2000, 14, 1293-1307. (Pubitemid 30397073)
30. Chen, S.; Li, Z.; Li, W.; Shan, Z.; Zhu, W. Resveratrol inhibits cell differentiation in 3T3-L1 adipocytes via activation of AMPK. Can. J. Physiol. Pharmacol. 2011, 89, 793-799.
31. Yao-Borengasser, A.; Rassouli, N.; Varma, V.; Bodles, A.M.; Rasouli, N.; Unal, R.; Phanavanh, B.; Ranganathan, G.; McGehee, R.E., Jr.; Kern, P.A. Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferatoractivated receptor-gamma responsiveness. J. Clin. Endocrinol. MeTable 2008, 93, 4431-4439. (Pubitemid 352789544)
32. Kim, E.; Lee, J.H.; Ntambi, J.M.; Hyun, C.K. Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro. Eur. J. Pharmacol. 2011, 672, 38-44.
33. Jung, D.; Abu-Elheiga, L.; Ayuzawa, R.; Gu, Z.; Shirakawa, T.; Fujiki, Y.; Nakatsuji, N.; Wakil, S.J.; Uesugi, M. Mislocalization and inhibition of acetyl-CoA carboxylase 1 by a synthetic small molecule. Biochem. J. 2012, 448, 409-416.
34. Abu-Elheiga, L.; Matzuk, M.M.; Kordari, P.; Oh, W.; Shaikenov, T.; Gu, Z.; Wakil, S.J. Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. Proc. Natl. Acad. Sci. USA 2005, 102, 12011-12016. (Pubitemid 41291120)
35. Smith, S. The animal fatty acid synthase: one gene, one polypeptide, seven enzymes. FASEB J. 1994, 8, 1248-1259.
36. Lee, M.; Song, J.Y.; Chin, Y.W.; Sung, S.H. Anti-adipogenic diarylheptanoids from Alnus hirsuta f. sibirica on 3T3-L1 cells. Bioorg. Med. Chem. Lett. 2013, 23, 2069-2073.
37. Popivanova, B.K.; Kitamura, K.; Wu, Y.; Kondo, T.; Kagaya, T.; Kaneko, S.; Oshima, M.; Fujii, C.; Mukaida, N. Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis. J. Clin. Invest. 2008, 118, 560-570. (Pubitemid 351206546)