-
1
-
-
33645745475
-
Targeting PIM kinases impairs survival of hematopoietic cells transformed by kinase inhibitor-sensitive and kinase inhibitor-resistant forms of FMS-like tyrosine kinase 3 and BCR/ABL
-
Adam M., Pogacic V., Bendit M., Chappuis R., Nawijn M. C., Duyster J., Fox C. J., Thompson C. B., Cools J., Schwaller J.: Targeting PIM kinases impairs survival of hematopoietic cells transformed by kinase inhibitor-sensitive and kinase inhibitor-resistant forms of FMS-like tyrosine kinase 3 and BCR/ABL. Cancer Res., 2006;66:3828-3835
-
(2006)
Cancer Res.
, vol.66
, pp. 3828-3835
-
-
Adam, M.1
Pogacic, V.2
Bendit, M.3
Chappuis, R.4
Nawijn, M.C.5
Duyster, J.6
Fox, C.J.7
Thompson, C.B.8
Cools, J.9
Schwaller, J.10
-
2
-
-
0024408829
-
The human proto-oncogene product p33pim is expressed during fetal haematopoiesis and in diverse leukaemias
-
Amson R., Sigaux F., Przedborski S., Flandrin G., Givol D., Telerman A.: The human proto-oncogene product p33pim is expressed during fetal haematopoiesis and in diverse leukaemias. Proc. Natl. Acad. Sci. USA, 1989;86:8857-8861
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 8857-8861
-
-
Amson, R.1
Sigaux, F.2
Przedborski, S.3
Flandrin, G.4
Givol, D.5
Telerman, A.6
-
3
-
-
79960240251
-
The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells
-
Asano J., Nakano A., Oda A., Amou H., Hiasa M., Takeuchi K., Miki H., Nakamura S., Harada T., Fujii S., Kagawa K., Endo I., Yata K., Sakai A., Ozaki S., Matsumoto T., Abe M.: The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells. Leukemia, 2011;25:1182-1188
-
(2011)
Leukemia
, vol.25
, pp. 1182-1188
-
-
Asano, J.1
Nakano, A.2
Oda, A.3
Amou, H.4
Hiasa, M.5
Takeuchi, K.6
Miki, H.7
Nakamura, S.8
Harada, T.9
Fujii, S.10
Kagawa, K.11
Endo, I.12
Yata, K.13
Sakai, A.14
Ozaki, S.15
Matsumoto, T.16
Abe, M.17
-
4
-
-
0032497808
-
The human Pim-2 proto-oncogene and its testicular expression
-
Baytel D., Shalom S., Madgar I., Weissenberg R., Don J.: The human Pim-2 proto-oncogene and its testicular expression. Biochim. Biophys. Acta, 1998;1442:274-285
-
(1998)
Biochim. Biophys. Acta
, vol.1442
, pp. 274-285
-
-
Baytel, D.1
Shalom, S.2
Madgar, I.3
Weissenberg, R.4
Don, J.5
-
5
-
-
9144271651
-
Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - A Europe against cancer program
-
Beillard E., Pallisgaard N., van der Velden V H J., Bi W., Dee R., van der Schoot E., Delabesse E., Macintyre E., Gottardi E., Saglio G., Watzinger F., Lion T., van Dongen J. J., Hokland P., Gabert J.: Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program. Leukemia, 2003;17:2474-2486
-
(2003)
Leukemia
, vol.17
, pp. 2474-2486
-
-
Beillard, E.1
Pallisgaard, N.2
Van Der Velden, V.H.J.3
Bi, W.4
Dee, R.5
Van Der Schoot, E.6
Delabesse, E.7
Macintyre, E.8
Gottardi, E.9
Saglio, G.10
Watzinger, F.11
Lion, T.12
Van Dongen, J.J.13
Hokland, P.14
Gabert, J.15
-
6
-
-
77953180976
-
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers
-
Brault L., Gasser C., Bracher F., Huber K., Knapp S., Schwaller J.: PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers. Haematologica, 2010;95:1004-1015
-
(2010)
Haematologica
, vol.95
, pp. 1004-1015
-
-
Brault, L.1
Gasser, C.2
Bracher, F.3
Huber, K.4
Knapp, S.5
Schwaller, J.6
-
7
-
-
0024453705
-
Evidence for the involvement of pim-2, a new common proviral insertion site, in progression of lymphomas
-
Breuer M. L., Cuypers H. T., Berns A.: Evidence for the involvement of pim-2, a new common proviral insertion site, in progression of lymphomas. EMBO J., 1989;8:743-748
-
(1989)
EMBO J.
, vol.8
, pp. 743-748
-
-
Breuer, M.L.1
Cuypers, H.T.2
Berns, A.3
-
8
-
-
77950538522
-
Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells
-
Chen L. S., Redkar S., Bearss D., Wierda W. G., Gandhi V.: Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells. Blood, 2009;114:4150-4157
-
(2009)
Blood
, vol.114
, pp. 4150-4157
-
-
Chen, L.S.1
Redkar, S.2
Bearss, D.3
Wierda, W.G.4
Gandhi, V.5
-
9
-
-
1542753559
-
Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
-
International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
-
Cheson B. D., Bennett J. M., Kopecky K. J., Büchner T., Willman C. L., Estey E. H., Schiffer C. A., Doehner H., Tallman M. S., Lister T. A., Lo-Coco F., Willemze R., Biondi A., Hiddemann W., Larson R. A., Löwenberg B., Sanz M. A., Head D. R., Ohno R., Bloomfield C. D., International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia: Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia. J. Clin. Oncol., 2003;21:4642-4649
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 4642-4649
-
-
Cheson, B.D.1
Bennett, J.M.2
Kopecky, K.J.3
Büchner, T.4
Willman, C.L.5
Estey, E.H.6
Schiffer, C.A.7
Doehner, H.8
Tallman, M.S.9
Lister, T.A.10
Lo-Coco, F.11
Willemze, R.12
Biondi, A.13
Hiddemann, W.14
Larson, R.A.15
Löwenberg, B.16
Sanz, M.A.17
Head, D.R.18
Ohno, R.19
Bloomfield, C.D.20
more..
-
10
-
-
11144354804
-
Increased expression of the hPim-2 gene in human chronic lymphocytic leukaemia and non-Hodgkin lymphoma
-
Cohen A. M., Grinblat B., Bessler H., Kristt D., Kremer A., Schwartz A., Halperin M., Shalom S., Merkel D., Don J.: Increased expression of the hPim-2 gene in human chronic lymphocytic leukaemia and non-Hodgkin lymphoma. Leuk. Lymphoma, 2004;45:951-955
-
(2004)
Leuk. Lymphoma
, vol.45
, pp. 951-955
-
-
Cohen, A.M.1
Grinblat, B.2
Bessler, H.3
Kristt, D.4
Kremer, A.5
Schwartz, A.6
Halperin, M.7
Shalom, S.8
Merkel, D.9
Don, J.10
-
11
-
-
26644434368
-
Pim-2 upregulation: Biological implications associated with disease progression and perinueral invasion in prostate cancer
-
Dai H., Li R., Wheeler T., Diaz de Vivar A., Frolov A., Tahir S., Agoulnik I., Thompson T., Rowley D., Ayala G.: Pim-2 upregulation: biological implications associated with disease progression and perinueral invasion in prostate cancer. Prostate, 2005;65:276-286
-
(2005)
Prostate
, vol.65
, pp. 276-286
-
-
Dai, H.1
Li, R.2
Wheeler, T.3
Diaz De Vivar, A.4
Frolov, A.5
Tahir, S.6
Agoulnik, I.7
Thompson, T.8
Rowley, D.9
Ayala, G.10
-
12
-
-
15244356381
-
Antisense oligodeoxynucleotides targeting the serine/threonine kinase Pim-2 inhibited proliferation of DU-145 cells
-
Dai J. M., Zhang S. Q., Zhang W., Lin R. X., Ji Z. Z., Wang S. Q.: Antisense oligodeoxynucleotides targeting the serine/threonine kinase Pim-2 inhibited proliferation of DU-145 cells. Acta Pharmacol. Sin., 2005;26:364-368
-
(2005)
Acta Pharmacol. Sin.
, vol.26
, pp. 364-368
-
-
Dai, J.M.1
Zhang, S.Q.2
Zhang, W.3
Lin, R.X.4
Ji, Z.Z.5
Wang, S.Q.6
-
13
-
-
0042626302
-
The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor
-
Fox C. J., Hammerman P. S., Cinalli R. M., Master S. R., Chodosh L. A., Thompson C. B.: The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor. Gene Dev., 2003;17:1841-1854
-
(2003)
Gene Dev.
, vol.17
, pp. 1841-1854
-
-
Fox, C.J.1
Hammerman, P.S.2
Cinalli, R.M.3
Master, S.R.4
Chodosh, L.A.5
Thompson, C.B.6
-
14
-
-
68449096765
-
Impact of granulocyte colony stimulating factor administered during induction and consolidation of adults with acute lymphoblastic leukemia on survival: Long-term follow-up of the Polish adult leukemia group 4-96 study
-
Giebel S., Holowiecki J., Krawczyk-Kulis M., Jagoda K., Stella-Holowiecka B., Sadus-Wojciechowska M., Hellmann A., Dmoszynska A., Paluszewska M., Robak T., Konopka L., Seferynska I., Skotnicki A. B., Kyrcz-Krzemien S.: Impact of granulocyte colony stimulating factor administered during induction and consolidation of adults with acute lymphoblastic leukemia on survival: long-term follow-up of the Polish adult leukemia group 4-96 study. Leuk. Lymphoma, 2009;50:1050-1053
-
(2009)
Leuk. Lymphoma
, vol.50
, pp. 1050-1053
-
-
Giebel, S.1
Holowiecki, J.2
Krawczyk-Kulis, M.3
Jagoda, K.4
Stella-Holowiecka, B.5
Sadus-Wojciechowska, M.6
Hellmann, A.7
Dmoszynska, A.8
Paluszewska, M.9
Robak, T.10
Konopka, L.11
Seferynska, I.12
Skotnicki, A.B.13
Kyrcz-Krzemien, S.14
-
15
-
-
63649150059
-
Serine/threonine kinase Pim-2 promotes liver tumorigenesis induction through mediating survival and preventing apoptosis of liver cell
-
Gong J., Wang J., Ren K., Liu C., Li B., Shi Y.: Serine/threonine kinase Pim-2 promotes liver tumorigenesis induction through mediating survival and preventing apoptosis of liver cell. J. Surg. Res., 2009;153:17-22
-
(2009)
J. Surg. Res.
, vol.153
, pp. 17-22
-
-
Gong, J.1
Wang, J.2
Ren, K.3
Liu, C.4
Li, B.5
Shi, Y.6
-
16
-
-
19344374597
-
Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival
-
Hammerman P. S., Fox C. J., Brinbaum M. J., Thompson C. B.: Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival. Blood, 2005;105:4477-4483
-
(2005)
Blood
, vol.105
, pp. 4477-4483
-
-
Hammerman, P.S.1
Fox, C.J.2
Brinbaum, M.J.3
Thompson, C.B.4
-
17
-
-
8544263854
-
Lymphocyte transformation by Pim-2 is dependent on nuclear factor-κB activation
-
Hammerman P. S., Fox C. J., Cinalli R. M., Xu A., Wagner J. D., Lindsten T., Thompson C. B.: Lymphocyte transformation by Pim-2 is dependent on nuclear factor-κB activation. Cancer Res., 2004;64:8341-8348
-
(2004)
Cancer Res.
, vol.64
, pp. 8341-8348
-
-
Hammerman, P.S.1
Fox, C.J.2
Cinalli, R.M.3
Xu, A.4
Wagner, J.D.5
Lindsten, T.6
Thompson, C.B.7
-
18
-
-
2342534391
-
Addition of cladribine to daunorubicin and cytarabine increases complete remission rate after a single course of induction treatment in acute myeloid leukemia. Multicenter, phase III study
-
Polish Adult Leukemia Group PALG
-
Hołowiecki J., Grosicki S., Robak T., Kyrcz-Krzemien S., Giebel S., Hellmann A., Skotnicki A., Jedrzejczak W. W., Konopka L., Kuliczkowski K., Zdziarska B., Dmoszynska A., Marianska B., Pluta A., Zawilska K., Komarnicki M., Kloczko J., Sulek K., Haus O., Stella-Holowiecka B., Baran W., Jakubas B., Paluszewska M., Wierzbowska A., Kielbinski M., Jagoda K., Polish Adult Leukemia Group (PALG): Addition of cladribine to daunorubicin and cytarabine increases complete remission rate after a single course of induction treatment in acute myeloid leukemia. Multicenter, phase III study. Leukemia, 2004;18:989-997
-
(2004)
Leukemia
, vol.18
, pp. 989-997
-
-
Hołowiecki, J.1
Grosicki, S.2
Robak, T.3
Kyrcz-Krzemien, S.4
Giebel, S.5
Hellmann, A.6
Skotnicki, A.7
Jedrzejczak, W.W.8
Konopka, L.9
Kuliczkowski, K.10
Zdziarska, B.11
Dmoszynska, A.12
Marianska, B.13
Pluta, A.14
Zawilska, K.15
Komarnicki, M.16
Kloczko, J.17
Sulek, K.18
Haus, O.19
Stella-Holowiecka, B.20
Baran, W.21
Jakubas, B.22
Paluszewska, M.23
Wierzbowska, A.24
Kielbinski, M.25
Jagoda, K.26
more..
-
19
-
-
77950955440
-
Human Pim-2 expression in acute myeloid and acute lymphoblastic leukemia patients and complete remission
-
Kapelko-Słowik K., Urbaniak-Kujda D., Wołowiec D., Dybko J., Słowik M., Potoczek S., Kuliczkowski K.: Human Pim-2 expression in acute myeloid and acute lymphoblastic leukemia patients and complete remission. Adv. Clin. Exp. Med., 2010;19, 99-104
-
(2010)
Adv. Clin. Exp. Med.
, vol.19
, pp. 99-104
-
-
Kapelko-Słowik, K.1
Urbaniak-Kujda, D.2
Wołowiec, D.3
Dybko, J.4
Słowik, M.5
Potoczek, S.6
Kuliczkowski, K.7
-
20
-
-
0036009115
-
NF-κB at the crossroads of life and death
-
Karin M., Lin A.: NF-κB at the crossroads of life and death. Nat. Immunol., 2002;3:221-227
-
(2002)
Nat. Immunol.
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
21
-
-
0036781052
-
NF-κB regulation in the immune system
-
Li Q., Verma I. M.: NF-κB regulation in the immune system. Nat. Rev. Immunol., 2002;2:725-734
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
22
-
-
0037376895
-
NF-κB in cancer: A marked targed
-
Lin A., Karin M.: NF-κB in cancer: a marked targed. Semin. Cancer Biol., 2003;13:107-114
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 107-114
-
-
Lin, A.1
Karin, M.2
-
23
-
-
32944458740
-
Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL
-
Macdonald A., Campbell D. G., Toth R., McLauchlan H., Hastie C. J., Arthur J. S.: Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL. BMC Cell Biol., 2006;7:1-14
-
(2006)
BMC Cell Biol.
, vol.7
, pp. 1-14
-
-
Macdonald, A.1
Campbell, D.G.2
Toth, R.3
McLauchlan, H.4
Hastie, C.J.5
Arthur, J.S.6
-
24
-
-
0036729878
-
High-throughput retroviral tagging to indentify components of specific signaling pathways in cancer
-
Mikkers H., Allen J., Knipscheer P., Romeijn L., Hart A., Vink E., Berns A.: High-throughput retroviral tagging to indentify components of specific signaling pathways in cancer. Nat. Genet., 2002;32:153-159
-
(2002)
Nat. Genet.
, vol.32
, pp. 153-159
-
-
Mikkers, H.1
Allen, J.2
Knipscheer, P.3
Romeijn, L.4
Hart, A.5
Vink, E.6
Berns, A.7
-
25
-
-
0037944120
-
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations
-
Mizuki M., Schwable J., Steur C., Choudhary C., Agrawal S., Sargin B., Steffen B., Matsumura I., Kanakura Y., Böhmer F. D., Müller-Tidow C., Berdel W. E., Serve H.: Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations. Blood, 2003;101:3164-3173
-
(2003)
Blood
, vol.101
, pp. 3164-3173
-
-
Mizuki, M.1
Schwable, J.2
Steur, C.3
Choudhary, C.4
Agrawal, S.5
Sargin, B.6
Steffen, B.7
Matsumura, I.8
Kanakura, Y.9
Böhmer, F.D.10
Müller-Tidow, C.11
Berdel, W.E.12
Serve, H.13
-
26
-
-
0025006441
-
Primary structure of the putative human oncogene, pim-1
-
Reeves R., Spies G. A., Kiefer M., Barr P. J., Power M.: Primary structure of the putative human oncogene, pim-1. Gene, 1990;90:303-307
-
(1990)
Gene
, vol.90
, pp. 303-307
-
-
Reeves, R.1
Spies, G.A.2
Kiefer, M.3
Barr, P.J.4
Power, M.5
-
27
-
-
77956515318
-
Ectopic over-expression of oncogene Pim-2 induce malignant transformation of nontumorous human liver cell line L02
-
Ren K., Duan W., Shi Y., Li B., Liu Z., Gong J.: Ectopic over-expression of oncogene Pim-2 induce malignant transformation of nontumorous human liver cell line L02. J. Korean Med. Sci., 2010;25:1017-1023
-
(2010)
J. Korean Med. Sci.
, vol.25
, pp. 1017-1023
-
-
Ren, K.1
Duan, W.2
Shi, Y.3
Li, B.4
Liu, Z.5
Gong, J.6
-
28
-
-
77955714741
-
Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-κB pathway
-
Ren K., Zhang W., Shi Y., Gong J.: Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-κB pathway. Pathol. Oncol. Res., 2010;16:229-237
-
(2010)
Pathol. Oncol. Res.
, vol.16
, pp. 229-237
-
-
Ren, K.1
Zhang, W.2
Shi, Y.3
Gong, J.4
-
29
-
-
70349576526
-
Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia
-
Tamburini J., Green A. S., Bardet V., Chapuis N., Park S., Willems L., Uzunov M., Ifrah N., Dreyfus F., Lacombe C., Mayeux P., Bouscary D.: Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia. Blood, 2009;114:1618-1627
-
(2009)
Blood
, vol.114
, pp. 1618-1627
-
-
Tamburini, J.1
Green, A.S.2
Bardet, V.3
Chapuis, N.4
Park, S.5
Willems, L.6
Uzunov, M.7
Ifrah, N.8
Dreyfus, F.9
Lacombe, C.10
Mayeux, P.11
Bouscary, D.12
-
30
-
-
0043127142
-
The pims and outs of survival signaling: Role for the Pim-2 protein kinase in the suppression of apoptosis by cytokines
-
White E.: The pims and outs of survival signaling: role for the Pim-2 protein kinase in the suppression of apoptosis by cytokines. Genes Dev., 2003;17:1813-1816
-
(2003)
Genes Dev.
, vol.17
, pp. 1813-1816
-
-
White, E.1
-
31
-
-
0242580961
-
The PIM-2 kinase phosphorylates Bad on serine 112 and reverses Bad-induced cell death
-
Yan B., Zemskova M., Holder S., Chin V., Kraft A., Koskinen P. J., Lilly M.: The PIM-2 kinase phosphorylates Bad on serine 112 and reverses Bad-induced cell death. J. Biol. Chem., 2003;278:45358-45367
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45358-45367
-
-
Yan, B.1
Zemskova, M.2
Holder, S.3
Chin, V.4
Kraft, A.5
Koskinen, P.J.6
Lilly, M.7
-
32
-
-
4544248359
-
Polymerase synthesis and potential interference of a small-interfering RNA targeting hPim-2
-
Zhang S. Q., Du Q. Y., Ying Y., Ji Z. Z., Wang S. Q.: Polymerase synthesis and potential interference of a small-interfering RNA targeting hPim-2. World J. Gastroenterol., 2004;10:2657-2660
-
(2004)
World J. Gastroenterol.
, vol.10
, pp. 2657-2660
-
-
Zhang, S.Q.1
Du, Q.Y.2
Ying, Y.3
Ji, Z.Z.4
Wang, S.Q.5
|