World Health Organization. Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003-2013. July 2013. http://www.who.int/influenza/human-animal-interface/ EN-GIP- 20130705CumulativeNumberH5N1cases-2.pdf.
Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
Imai M, Watanabe T, Hatta M, et al. Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature 2012; 486:420-8.
The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host
Russell CA, Fonville JM, Brown AE, et al. The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host. Science 2012; 336:1541-7.
Public health and biosecurity Adaptations of avian flu virus are a cause for concern
Berns KI, Casadevall A, Cohen ML, et al. Public health and biosecurity. Adaptations of avian flu virus are a cause for concern. Science 2012; 335:660-1.
Identification and structural characterization of a broadly neutralizing antibody targeting a novel conserved epitope on the influenza virus H5N1 hemagglutinin
Du L, Jin L, Zhao G, et al. Identification and structural characterization of a broadly neutralizing antibody targeting a novel conserved epitope on the influenza virus H5N1 hemagglutinin. J Virol 2013; 87: 2215-25.
A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete crossclade protection against divergent H5N1 viruses
Du L, Leung VH, Zhang X, et al. A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete crossclade protection against divergent H5N1 viruses. PLoS One 2011; 6: E16555.
Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies
Du L, Zhao G, Zhang X, et al. Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies. Biochem Biophys Res Commun 2010; 397:580-5.
A critical HA1 neutralizing domain of H5N1 influenza in an optimal conformation induces strong cross-protection
Du L, Zhao G, Sun S, et al. A critical HA1 neutralizing domain of H5N1 influenza in an optimal conformation induces strong cross-protection. PLoS One 2013; 8:e53568.
Glycosylation at 158N of the hemagglutinin protein and receptor binding specificity synergistically affect the antigenicity and immunogenicity of a live attenuated H5N1 A/Vietnam/1203/2004 vaccine virus in ferrets
WangW, Lu B, Zhou H, et al. Glycosylation at 158N of the hemagglutinin protein and receptor binding specificity synergistically affect the antigenicity and immunogenicity of a live attenuated H5N1 A/Vietnam/1203/2004 vaccine virus in ferrets. J Virol 2010; 84:6570-7.