메뉴 건너뛰기




Volumn , Issue SEP, 2013, Pages

Miro, MCU, and calcium: Bridging our understanding of mitochondrial movement in axons

Author keywords

Axonal transport; MCU; MICU1; Miro; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; MCU1 PROTEIN; MEMBRANE PROTEIN; MICU1 PROTEIN; MIRO PROTEIN; MITOCHONDRIAL PROTEIN; OUTER MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

EID: 84885070787     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2013.00148     Document Type: Review
Times cited : (26)

References (30)
  • 1
    • 80051946060 scopus 로고    scopus 로고
    • Integrative genomics identi-fies MCU as an essential component of the mitochondrial calcium uniporter
    • doi: 10.1038/nature10234
    • Baughman, J. M., Perocchi, F., Girgis, H. S., Plovanich, M., Belcher-Timme, C. A., Sancak, Y., et al. (2011). Integrative genomics identi-fies MCU as an essential component of the mitochondrial calcium uniporter. Nature 476, 341-345. doi: 10.1038/nature10234
    • (2011) Nature , vol.476 , pp. 341-345
    • Baughman, J.M.1    Perocchi, F.2    Girgis, H.S.3    Plovanich, M.4    Belcher-Timme, C.A.5    Sancak, Y.6
  • 2
    • 79955972587 scopus 로고    scopus 로고
    • Trafficking kinesin protein (TRAK)-mediated transport of mitochondria in axons of hippocampal neurons
    • doi: 10.1074/jbc.M111.236018
    • Brickley, K., and Stephenson, F. A. (2011). Trafficking kinesin protein (TRAK)-mediated transport of mitochondria in axons of hippocampal neurons. J. Biol. Chem. 286, 18079-18092. doi: 10.1074/jbc.M111.236018
    • (2011) J. Biol. Chem. , vol.286 , pp. 18079-18092
    • Brickley, K.1    Stephenson, F.A.2
  • 3
    • 80053056620 scopus 로고    scopus 로고
    • 2+ as an intrinsic signal regulating mitochondrial motility in axons
    • doi: 10.1073/pnas.1106862108
    • 2+ as an intrinsic signal regulating mitochondrial motility in axons. Proc. Natl. Acad. Sci. U.S.A. 108, 15456-15461. doi: 10.1073/pnas.1106862108
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 15456-15461
    • Chang, K.T.1    Niescier, R.F.2    Min, K.-T.3
  • 4
    • 84879401464 scopus 로고    scopus 로고
    • Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture
    • doi: 10.1016/j.cell.2013. 05.021
    • Courchet, J., Lewis, T. L. Jr., Lee, S., Courchet, V., Liou, D. Y., Aizawa, S., et al. (2013). Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture. Cell 153, 1510-1525. doi: 10.1016/j.cell.2013. 05.021
    • (2013) Cell , vol.153 , pp. 1510-1525
    • Courchet, J.1    Lewis Jr., T.L.2    Lee, S.3    Courchet, V.4    Liou, D.Y.5    Aizawa, S.6
  • 5
    • 80051936634 scopus 로고    scopus 로고
    • A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
    • doi: 10.1038/nature10230
    • De Stefani, D., Raffaello, A., Teardo, E., Szabò, I., and Rizzuto, R. (2011). A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 476, 336-340. doi: 10.1038/nature10230
    • (2011) Nature , vol.476 , pp. 336-340
    • De Stefani, D.1    Raffaello, A.2    Teardo, E.3    Szabò, I.4    Rizzuto, R.5
  • 6
    • 0037458579 scopus 로고    scopus 로고
    • Atypical rho GTPases have roles in mitochondrial homeostasis and apoptosis
    • doi: 10.1074/jbc.M208609200
    • Fransson, A., Ruusala, A., and Aspenstrom, P. (2003). Atypical rho GTPases have roles in mitochondrial homeostasis and apoptosis. J. Biol. Chem. 278, 6495-6502. doi: 10.1074/jbc.M208609200
    • (2003) J. Biol. Chem. , vol.278 , pp. 6495-6502
    • Fransson, A.1    Ruusala, A.2    Aspenstrom, P.3
  • 7
    • 33646117742 scopus 로고    scopus 로고
    • The atypical rho GTPases miro-1 and miro-2 have essential roles in mitochondrial trafficking
    • doi: 10.1016/j.bbrc.2006.03.163
    • Fransson, A., Ruusala, A., and Aspenstrom, P. (2006). The atypical rho GTPases miro-1 and miro-2 have essential roles in mitochondrial trafficking. Biochem. Biophys. Res. Commun. 344, 500-510. doi: 10.1016/j.bbrc.2006.03.163
    • (2006) Biochem. Biophys. Res. Commun. , vol.344 , pp. 500-510
    • Fransson, A.1    Ruusala, A.2    Aspenstrom, P.3
  • 8
    • 33646768127 scopus 로고    scopus 로고
    • Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent
    • doi: 10.1083/jcb.2006 01067
    • Glater, E. E., Megeath, L. J., Stowers, R. S., and Schwarz, T. L. (2006). Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. J. Cell Biol. 173, 545-557. doi: 10.1083/jcb.2006 01067
    • (2006) J. Cell Biol. , vol.173 , pp. 545-557
    • Glater, E.E.1    Megeath, L.J.2    Stowers, R.S.3    Schwarz, T.L.4
  • 9
    • 0032499264 scopus 로고    scopus 로고
    • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
    • doi: 10.1038/33416
    • Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., et al. (1998). Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608. doi: 10.1038/33416
    • (1998) Nature , vol.392 , pp. 605-608
    • Kitada, T.1    Asakawa, S.2    Hattori, N.3    Matsumine, H.4    Yamamura, Y.5    Minoshima, S.6
  • 10
    • 67749122635 scopus 로고    scopus 로고
    • An ER-mitochondria tethering complex revealed by a synthetic biology screen
    • doi: 10.1126/science.1175088
    • Kornmann, B., Currie, E., Collins, S. R., Schuldiner, M., Nunnari, J., Weissman, J. S., et al. (2009). An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325, 477-481. doi: 10.1126/science.1175088
    • (2009) Science , vol.325 , pp. 477-481
    • Kornmann, B.1    Currie, E.2    Collins, S.R.3    Schuldiner, M.4    Nunnari, J.5    Weissman, J.S.6
  • 11
    • 80052172908 scopus 로고    scopus 로고
    • The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections
    • doi: 10.1073/pnas.1111314108
    • Kornmann, B., Osman, C., and Walter, P. (2011). The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections. Proc. Natl. Acad. Sci. U.S.A. 108, 14151-14156. doi: 10.1073/pnas.1111314108
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 14151-14156
    • Kornmann, B.1    Osman, C.2    Walter, P.3
  • 12
    • 60449108890 scopus 로고    scopus 로고
    • Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses
    • doi: 10.1016/j.neuron.2009.01.030
    • Macaskill, A. F., Rinholm, J. E., Twelvetrees, A. E., Arancibia-Carcamo, I. L., Muir, J., Fransson, A., et al. (2009). Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses. Neuron 61, 541-555. doi: 10.1016/j.neuron.2009.01.030
    • (2009) Neuron , vol.61 , pp. 541-555
    • McAskill, A.F.1    Rinholm, J.E.2    Twelvetrees, A.E.3    Arancibia-Carcamo, I.L.4    Muir, J.5    Fransson, A.6
  • 14
    • 84868027665 scopus 로고    scopus 로고
    • MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival
    • doi: 10.1016/j.cell.2012. 10.011
    • Mallilankaraman, K., Doonan, P., Cardenas, C., Chandramoorthy, H. C., Muller, M., Miller, R., et al. (2012b). MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival. Cell 151, 630-644. doi: 10.1016/j.cell.2012. 10.011
    • (2012) Cell , vol.151 , pp. 630-644
    • Mallilankaraman, K.1    Doonan, P.2    Cardenas, C.3    Chandramoorthy, H.C.4    Muller, M.5    Miller, R.6
  • 15
    • 75749156257 scopus 로고    scopus 로고
    • PINK1 is selectively stabilized on impaired mitochondria to activate parkin
    • doi: 10.1371/journal.pbio.1000298
    • Narendra, D. P., Jin, S. M., Tanaka, A., Suen, D. F., Gautier, C. A., Shen, J., et al. (2010). PINK1 is selectively stabilized on impaired mitochondria to activate parkin. PLoS Biol. 8:e1000298. doi: 10.1371/journal.pbio.1000298
    • (2010) PLoS Biol. , vol.8
    • Narendra, D.P.1    Jin, S.M.2    Tanaka, A.3    Suen, D.F.4    Gautier, C.A.5    Shen, J.6
  • 16
    • 84881311235 scopus 로고    scopus 로고
    • Regulation of mitochondrial dynamics and distribution by synapse position and neuronal activity in the axon
    • doi: 10.1111/ejn.12263
    • Obashi, K., and Okabe, S. (2013). Regulation of mitochondrial dynamics and distribution by synapse position and neuronal activity in the axon. Eur. J. Neurosci. 38, 2350-2363. doi: 10.1111/ejn.12263
    • (2013) Eur. J. Neurosci. , vol.38 , pp. 2350-2363
    • Obashi, K.1    Okabe, S.2
  • 17
    • 77956928316 scopus 로고    scopus 로고
    • MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake
    • doi: 10.1038/nature09358
    • Perocchi, F., Gohil, V. M., Girgis, H. S., Bao, X. R., McCombs, J. E., Palmer, A. E., et al. (2010). MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake. Nature 467, 291-296. doi: 10.1038/nature09358
    • (2010) Nature , vol.467 , pp. 291-296
    • Perocchi, F.1    Gohil, V.M.2    Girgis, H.S.3    Bao, X.R.4    McCombs, J.E.5    Palmer, A.E.6
  • 18
    • 33646759268 scopus 로고    scopus 로고
    • Kinesin-1 and dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons
    • doi: 10.1091/mbc.E05-06-0526
    • Pilling, A. D., Horiuchi, D., Lively, C. M., and Saxton, W. M. (2006). Kinesin-1 and dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons. Mol. Biol. Cell 17, 2057-2068. doi: 10.1091/mbc.E05-06-0526
    • (2006) Mol. Biol. Cell , vol.17 , pp. 2057-2068
    • Pilling, A.D.1    Horiuchi, D.2    Lively, C.M.3    Saxton, W.M.4
  • 19
    • 65649107618 scopus 로고    scopus 로고
    • Drosophila miro is required for both anterograde and retrograde axonal mitochondrial transport
    • doi: 10.1523/JNEUROSCI.5417-08.2009
    • Russo, G. J., Louie, K., Wellington, A., Macleod, G. T., Hu, F., Panchumarthi, S., et al. (2009). Drosophila miro is required for both anterograde and retrograde axonal mitochondrial transport. J. Neurosci. 29, 5443-5455. doi: 10.1523/JNEUROSCI.5417-08.2009
    • (2009) J. Neurosci. , vol.29 , pp. 5443-5455
    • Russo, G.J.1    Louie, K.2    Wellington, A.3    McLeod, G.T.4    Hu, F.5    Panchumarthi, S.6
  • 21
    • 84862870271 scopus 로고    scopus 로고
    • The axonal transport of mitochondria
    • doi: 10.1242/jcs.053850
    • Saxton, W. M., and Hollenbeck, P. J. (2012). The axonal transport of mitochondria. J. Cell Sci. 125, 2095-2104. doi: 10.1242/jcs.053850
    • (2012) J. Cell Sci. , vol.125 , pp. 2095-2104
    • Saxton, W.M.1    Hollenbeck, P.J.2
  • 22
    • 79959305691 scopus 로고    scopus 로고
    • Mitochondria: The next (neurode)generation
    • doi: 10.1016/j.neuron. 2011.06.003
    • Schon, E. A., and Przedborski, S. (2011). Mitochondria: the next (neurode)generation. Neuron 70, 1033-1053. doi: 10.1016/j.neuron. 2011.06.003
    • (2011) Neuron , vol.70 , pp. 1033-1053
    • Schon, E.A.1    Przedborski, S.2
  • 23
    • 84883613359 scopus 로고    scopus 로고
    • Distinct functions of nuclear distribution proteins LIS1, Ndel1 and NudCL in regulating axonal mitochondrial transport
    • doi: 10.1111/tra.12070
    • Shao, C. Y., Zhu, J., Xie, Y. J., Wang, Z., Wang, Y. N., Wang, Y., et al. (2013). Distinct functions of nuclear distribution proteins LIS1, Ndel1 and NudCL in regulating axonal mitochondrial transport. Traffic 14, 785-797. doi: 10.1111/tra.12070
    • (2013) Traffic , vol.14 , pp. 785-797
    • Shao, C.Y.1    Zhu, J.2    Xie, Y.J.3    Wang, Z.4    Wang, Y.N.5    Wang, Y.6
  • 24
    • 0037137704 scopus 로고    scopus 로고
    • Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein
    • doi: 10.1016/S0896-6273(02)01094-2
    • Stowers, R. S., Megeath, L. J., Gorska-Andrzejak, J., Meinertzhagen, I. A., and Schwarz, T. L. (2002). Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. Neuron 36, 1063-1077. doi: 10.1016/S0896-6273(02)01094-2
    • (2002) Neuron , vol.36 , pp. 1063-1077
    • Stowers, R.S.1    Megeath, L.J.2    Gorska-Andrzejak, J.3    Meinertzhagen, I.A.4    Schwarz, T.L.5
  • 25
    • 0032568790 scopus 로고    scopus 로고
    • Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria
    • doi: 10.1016/S0092-8674(00)81459-2
    • Tanaka, Y., Kanai, Y., Okada, Y., Nonaka, S., Takeda, S., Harada, A., et al. (1998). Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell 93, 1147-1158. doi: 10.1016/S0092-8674(00)81459-2
    • (1998) Cell , vol.93 , pp. 1147-1158
    • Tanaka, Y.1    Kanai, Y.2    Okada, Y.3    Nonaka, S.4    Takeda, S.5    Harada, A.6
  • 26
    • 0035068574 scopus 로고    scopus 로고
    • Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36
    • doi: 10.1086/ 319522
    • Valente, E. M., Bentivoglio, A. R., Dixon, P. H., Ferraris, A., Ialongo, T., Frontali, M., et al. (2001). Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36. Am. J. Hum. Genet. 68, 895-900. doi: 10.1086/ 319522
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 895-900
    • Valente, E.M.1    Bentivoglio, A.R.2    Dixon, P.H.3    Ferraris, A.4    Ialongo, T.5    Frontali, M.6
  • 27
    • 84873279659 scopus 로고    scopus 로고
    • TRAK/milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites
    • doi: 10.1016/j.neuron.2012. 11.027
    • van Spronsen, M., Mikhaylova, M., Lipka, J., Schlager, M. A., van den Heuvel, D. J., Kuijpers, M., et al. (2013). TRAK/milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites. Neuron 77, 485-502. doi: 10.1016/j.neuron.2012. 11.027
    • (2013) Neuron , vol.77 , pp. 485-502
    • van Spronsen, M.1    Mikhaylova, M.2    Lipka, J.3    Schlager, M.A.4    van den Heuvel, D.J.5    Kuijpers, M.6
  • 29
    • 58149091896 scopus 로고    scopus 로고
    • 2+-dependent regulation of kinesin-mediated mitochondrial motility
    • doi: 10.1016/j.cell.2008. 11.046
    • 2+-dependent regulation of kinesin-mediated mitochondrial motility. Cell 136, 163-174. doi: 10.1016/j.cell.2008. 11.046
    • (2009) Cell , vol.136 , pp. 163-174
    • Wang, X.1    Schwarz, T.L.2
  • 30
    • 81055140895 scopus 로고    scopus 로고
    • PINK1 and parkin target miro for phosphorylation and degradation to arrest mitochondrial motility
    • doi: 10.1016/j.cell.2011. 10.018
    • Wang, X., Winter, D., Ashrafi, G., Schlehe, J., Wong, Y. L., Selkoe, D., et al. (2011). PINK1 and parkin target miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 147, 893-906. doi: 10.1016/j.cell.2011. 10.018
    • (2011) Cell , vol.147 , pp. 893-906
    • Wang, X.1    Winter, D.2    Ashrafi, G.3    Schlehe, J.4    Wong, Y.L.5    Selkoe, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.