A Cocktail of Thermally Stable, Chemically Synthesized Capture Agents for the Efficient Detection of Anti-Gp41 Antibodies from Human Sera

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Pfeilsticker, Jessica A ^a   Umeda, Aiko ^a   Farrow, Blake ^b   Hsueh, Connie L ^a   Deyle, Kaycie M ^a   Kim, Jocelyn T ^b   Lai, Bert T ^c   Heath, James R ^a  

^a California Institute of Technology   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c Indi Molecular   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; EPITOPE; GLYCOPROTEIN GP 41; GLYCOPROTEIN GP 41 ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; POLYCLONAL ANTIBODY; PROTEIN CATALYZED CAPTURE AGENT; REAGENT; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY SPECIFICITY; ARTICLE; CLICK CHEMISTRY; CONTROLLED STUDY; GOLD STANDARD; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMORAL IMMUNITY; IN VITRO STUDY; SIGNAL NOISE RATIO; SYNTHESIS; TEMPERATURE MEASUREMENT; THERMOSTABILITY;

AMINO ACID SEQUENCE; ANTIBODIES, ANTI-IDIOTYPIC; CLICK CHEMISTRY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP41; HIV INFECTIONS; HIV SEROPOSITIVITY; HUMANS; MOLECULAR STRUCTURE; PEPTIDES; PROTEIN BINDING; PROTEIN STABILITY; SIGNAL-TO-NOISE RATIO; TEMPERATURE;

EID: 84885066081     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076224     Document Type: Article

References (19)

1. Brachman PS(1996) In: Baron S, editor. Medical Microbiology. 4th ed. Galveston (TX).
2. Fanales-Belasio E, Raimondo M, Suligoi B, Butto S, (2010) HIV virology and pathogenetic mechanisms of infection: a brief overview. Ann Ist Super Sanita 46: 5-14.
3. Alvarez M, Chueca N, Guillot V, Bernal Mdel C, Garcia F, (2012) Improving Clinical Laboratory Efficiency: Introduction of Systems for the Diagnosis and Monitoring of HIV Infection. Open Virol J 6: 135-143.
4. Tebourski F, Slim A, Elgaaied A, (2004) The significance of combining World Health Organization and Center for Disease Control criteria to resolve indeterminate human immunodeficiency virus type-1 Western blot results. Diagn Microbiol Infect Dis 48: 59-61.
5. Daskalakis D, (2011) HIV diagnostic testing: evolving technology and testing strategies. Top Antivir Med 19: 18-22.
6. Butto S, Suligoi B, Fanales-Belasio E, Raimondo M, (2010) Laboratory diagnostics for HIV infection. Ann Ist Super Sanita 46: 24-33.
7. Korenromp EL, Williams BG, Schmid GP, Dye C, (2009) Clinical prognostic value of RNA viral load and CD4 cell counts during untreated HIV-1 infection-a quantitative review. PLoS One 4: e5950.
8. Iweala OI, (2004) HIV diagnostic tests: an overview. Contraception 70: 141-147.
9. Ginocchio CC, Carman WF, Arens MQ, (2011) Update on HIV diagnostic testing algorithms. Editors' introduction. J Clin Virol 52Suppl 1: S1.
10. Agnew HD, Rohde RD, Millward SW, Nag A, Yeo WS, et al. (2009) Iterative in situ click chemistry creates antibody-like protein-capture agents. Angew Chem Int Ed Engl 48: 4944-4948.
11. Millward SW, Henning RK, Kwong GA, Pitram S, Agnew HD, et al. (2011) Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1. J Am Chem Soc 133: 18280-18288.
12. Huisgen R (1984) 1,3-Dipolar cycloaddition - introduction, survey, mechanism. In: Padwa A, editor. 1,3-Dipolar Cycloaddition Chemistry Wiley. 1-176.
13. Thirumurugan P, Matosiuk D, Jozwiak K (2013) Click Chemistry for Drug Development and Diverse Chemical-Biology Applications. Chem Rev.
14. Finn MG, Fokin VV, (2010) Click chemistry: function follows form. Chem Soc Rev 39: 1231-1232.
15. Lam KS, Lebl M, Krchnak V, (1997) The "One-Bead-One-Compound" Combinatorial Library Method. Chem Rev 97: 411-448.
16. Du AP, Limal D, Semetey V, Dali H, Jolivet M, et al. (2002) Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J Mol Biol 323: 503-521.
17. Xu JY, Gorny MK, Palker T, Karwowska S, Zolla-Pazner S, (1991) Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies. J Virol 65: 4832-4838.
18. Chin CD, Laksanasopin T, Cheung YK, Steinmiller D, Linder V, et al. (2011) Microfluidics-based diagnostics of infectious diseases in the developing world. Nat Med 17: 1015-1019.
19. Tiwari RP, Jain A, Khan Z, Kumar P, Bhrigu V, Bisen PS, (2013) Designing of novel antigenic peptide cocktail for the detection of antibodies to HIV-1/2 by ELISA. J Immun Meth 387: 157-166.