Epithelial to mesenchymal transition markers are associated with an increased metastatic risk in primary cutaneous squamous cell carcinomas but are attenuated in lymph node metastases

Journal of Dermatological Science

Volumn 72, Issue 2, 2013, Pages 93-102

  Toll, Agustí ^a   Masferrer, Emili ^a   Hernandez Ruiz M E ^a   Ferrandiz Pulido, Carla ^b   Yébenes, Mireia ^c   Jaka, Ane ^d   Tuneu, Anna ^d   Jucglà, Anna ^e   Gimeno, Javier ^a   Baró, Teresa ^a   Casado, Beatriz ^a   Gandarillas, Alberto ^f   Costa, Irmgard ^c   Mojal, Sergi ^a   Peña, Raul ^a   de Herreros, Antonio García ^a   García Patos, Vicenç ^b   Pujol, Ramon M ^a   Hernández Muñoz, Inmaculada ^a  

^a HOSPITAL DEL MAR   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c Hospital Universitari Vall d'Hebron ^*  (Spain)

^d HOSPITAL DONOSTIA   (Spain)

^e HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^f HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

Author keywords

Cutaneous squamous cell carcinoma; E cadherin; Epithelial to mesenchymal transition; Metastasis; Twist; Vimentin

Indexed keywords

BETA CATENIN; PODOPLANIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR ZEB1; UVOMORULIN; VIMENTIN; CADHERIN; CDH1 PROTEIN, HUMAN; CTNNB1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; MEMBRANE PROTEIN; NUCLEAR PROTEIN; PDPN PROTEIN, HUMAN; SNAIL FAMILY TRANSCRIPTION FACTORS; TUMOR MARKER; TWIST1 PROTEIN, HUMAN; ZEB1 PROTEIN, HUMAN;

AGED; ARTICLE; CELL ADHESION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MALE; METASTASIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; SKIN CARCINOMA; TISSUE MICROARRAY; GENE EXPRESSION REGULATION; METABOLISM; RISK; SKIN TUMOR; SQUAMOUS CELL CARCINOMA;

BETA CATENIN; CADHERINS; CARCINOMA, SQUAMOUS CELL; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MEMBRANE GLYCOPROTEINS; NUCLEAR PROTEINS; PHENOTYPE; RETROSPECTIVE STUDIES; RISK; SKIN NEOPLASMS; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL; TWIST TRANSCRIPTION FACTOR; VIMENTIN;

EID: 84885062917     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2013.07.001     Document Type: Article

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