The interplay of the interleukin 1 system in pregnancy and labor

Reproductive Sciences

Volumn 21, Issue 1, 2014, Pages 122-130

  Heng, Yujing Jan ^a,b,c   Liong, Stella ^a,b   Permezel, Michael ^a,b   Rice, Gregory E ^d   Quinzio, Megan K W Di ^a,b   Georgiou, Harry M ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MERCY HOSPITAL FOR WOMEN   (Australia)

^c MOUNT SINAI HOSPITAL   (Canada)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

cervicovaginal fluid; interleukin 1; interleukin 1 receptor antagonist; labor; pregnancy

Indexed keywords

CLOTRIMAZOLE; ERYTHROMYCIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA;

ADULT; ARTICLE; CANDIDA; CANDIDIASIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GESTATIONAL AGE; HUMAN; LABOR; LABOR ONSET; MAJOR CLINICAL STUDY; OBSERVATIONAL STUDY; PREGNANCY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEXUAL INTERCOURSE; THIRD TRIMESTER PREGNANCY; UREAPLASMA; UREAPLASMA INFECTION; VAGINA FLORA;

CERVICOVAGINAL FLUID; INTERLEUKIN-1; INTERLEUKIN-1 RECEPTOR ANTAGONIST; LABOR; PREGNANCY;

ADULT; BIOLOGICAL MARKERS; CERVIX UTERI; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GESTATIONAL AGE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; LABOR, OBSTETRIC; LONGITUDINAL STUDIES; PREDICTIVE VALUE OF TESTS; PREGNANCY; SIGNAL TRANSDUCTION; TERM BIRTH; UNSAFE SEX; VAGINA;

EID: 84885061372     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719113492204     Document Type: Article

References (45)

1. Di Quinzio MK, Oliva K, Holdsworth SJ, et al. Proteomic analysis and characterisation of human cervico-vaginal fluid proteins. Aust N Z J Obstet Gynaecol. 2007 ; 47 (1). 9-15
2. Pereira L, Reddy AP, Jacob T, et al. Identification of novel protein biomarkers of preterm birth in human cervical-vaginal fluid. J Proteome Res. 2007 ; 6 (4). 1269-1276
3. Honest H, Bachamann LM, Gupta JK, Kleijnen J, Khan KS. Accuracy of cervicovaginal fetal fibronectin test in predicting risk of spontaneous preterm birth: systematic review. BMJ. 2002 ; 325 (7359). 301
4. Norwitz ER, Snegovskikh VV, Caughey AB. Prolonged pregnancy: when should we intervene?. Clin Obstet Gynecol. 2007 ; 50 (2). 547-557
5. Lockwood CJ, Moscarelli RD, Wein R, et al. Low concentrations of vaginal fetal fibronectin as a predictor of deliveries occurring after 41 weeks. Am J Obstet Gynecol. 1994 ; 171 (1). 1-4
6. Lagrew DC, Freeman RK. Management of postdate pregnancy. Am J Obstet Gynecol. 1986 ; 154 (1). 8-13
7. Di Quinzio MK, Georgiou HM, Holdsworth-Carson SJ, et al. Proteomic analysis of human cervico-vaginal fluid displays differential protein expression in association with labor onset at term. J Proteome Res. 2008 ; 7 (5). 1916-1921
8. Heng YJ, Di Quinzio MK, Permezel M, Rice GE, Georgiou HM. Interleukin-1 receptor antagonist in human cervicovaginal fluid in term pregnancy and labor. Am J Obstet Gynecol. 2008 ; 199 (6). 656
9. Efrati P, Presentey B, Margalith M, Rozenszajn L.. Leukocytes of normal pregnant women. Obstet Gynecol. 1964 ; 23: 429 e1-432 7
10. Liggins GC. The Cervix in Pregnancy and Labour. Ellwood DA Anderson ABM Embrey MP, ed. Edinburgh, IN: Churchill-Livingstone ; 1989:1-9 :
11. Haddad R, Tromp G, Kuivaniemi H, et al. Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am J Obstet Gynecol. 2006 ; 195 (2). 394
12. Osman I, Young A, Ledingham M, et al. Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term. Mol Hum Reprod. 2003 ; 9 (1). 41-45
13. Thomson AJ, Telfer JF, Young A, et al. Leukocytes infiltrate the myometrium during human parturition: further evidence that labour is an inflammatory process. Hum Reprod. 1999 ; 14 (1). 229-236
14. Arend WP, Malyak M, Guthridge CJ, Gabay C. Interleukin-1 receptor antagonist: role in biology. Annu Rev Immunol. 1998 ; 16: 27-55
15. Rizzo G, Capponi A, Rinaldo D, et al. Interleukin-6 concentrations in cervical secretions identify microbial invasion of the amniotic cavity in patients with preterm labor and intact membranes. Am J Obstet Gynecol. 1996 ; 175 (4 pt 1). 812-817
16. Tanaka Y, Narahara H, Takai N, Yoshimatsu J, Anai T, Miyakawa I. Interleukin-1beta and interleukin-8 in cervicovaginal fluid during pregnancy. Am J Obstet Gynecol. 1998 ; 179 (3 pt 1). 644-649
17. Imai M, Tani A, Saito M, Saito K, Amano K, Nisijima M. Significance of fetal fibronectin and cytokine measurement in the cervicovaginal secretions of women at term in predicting term labor and post-term pregnancy. Eur J Obstet Gynaecol Reprod Biol. 2001 ; 97 (1). 53-58
18. Cox SM, King MR, Casey ML, MacDonald PC. Interleukin-1 beta, -1 alpha, and -6 and prostaglandins in vaginal/cervical fluids of pregnant women before and during labor. J Clin Endocrinol Metab. 1993 ; 77 (3). 805-815
19. Imseis HM, Greig PC, Livengood CH III, Shunior E, Durda P, Erikson M. Characterization of the inflammatory cytokines in the vagina during pregnancy and labor and with bacterial vaginosis. J Soc Gynecol Investig. 1997 ; 4 (2). 90-94
20. Heng YJ, Di Quinzio MK, Permezel M, Rice GE, Georgiou HM. Temporal expression of antioxidants in human cervicovaginal fluid associated with spontaneous labor. Antioxid Redox Signal. 2010 ; 13 (7). 951-957
21. Heng YJ, Di Quinzio MK, Permezel M, Rice GE, Georgiou HM.. Cystatin A protease inhibitor and cysteine proteases in human cervicovaginal fluid in term pregnancy and labor. Am J Obstet Gynecol. 2011 ; 204 (3). e251 - e257
22. Heng YJ, Di Quinzio MK, Liong S, et al. Temporal investigation of matrix metalloproteinases and their inhibitors in human cervicovaginal fluid in late pregnancy and labor. Reprod Sci. 2012 ; 19 (1). 55-63
23. Unal ER, Cierny JT, Roedner C, Newman R, Goetzl L.. Maternal inflammation in spontaneous term labor. Am J Obstet Gynecol. 2011 ; 204 (3). e221 - e225
24. Markovic D, Vatish M, Gu M, et al. The onset of labor alters corticotropin-releasing hormone type 1 receptor variant expression in human myometrium: putative role of interleukin-1beta. Endocrinology. 2007 ; 148 (7). 3205-3213
25. Schmitz T, Leroy MJ, Dallot E, Breuiller-Fouche M, Ferre F, Cabrol D. Interleukin-1beta induces glycosaminoglycan synthesis via prostaglandin E2 pathway in cultured human cervical fibroblasts. Mol Hum Reprod. 2003 ; 9 (1). 1-8
26. Ämmälä M, Nyman T, Salmi A, Rutanen EM. The interleukin-1 system in gestational tissues at term: effect of labour. Placenta. 1997 ; 18 (8). 717-723
27. Opsjøn SL, Wathen NC, Tingulstad S, et al. Tumor necrosis factor, interleukin-1, and interleukin-6 in normal human pregnancy. Am J Obstet Gynecol. 1993 ; 169 (2 pt 1). 397-404
28. Keelan JA, Marvin KW, Sato TA, Coleman M, McCowan LM, Mitchell MD. Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition. Am J Obstet Gynecol. 1999 ; 181 (6). 1530-1536
29. Romero R, Brody DT, Oyarzun E, et al. Infection and labor. III. Interleukin-1: a signal for the onset of parturition. Am J Obstet Gynecol. 1989 ; 160 (5 pt 1). 1117-1123
30. Romero R, Sepulveda W, Mazor M, et al. The natural interleukin-1 receptor antagonist in term and preterm parturition. Am J Obstet Gynecol. 1992 ; 167 (4 pt 1). 863-872
31. Mitchell MD, Edwin SS, Silver RM, Romero RJ. Potential agonist action of the interleukin-1 receptor antagonist protein: implications for treatment of women. J Clin Endocrinol Metab. 1993 ; 76 (4 pt 1). 1386-1388
32. Brown NL, Alvi SA, Elder MG, Bennett PR, Sullivan MH. Regulation of prostaglandin production in intact fetal membranes by interleukin-1 and its receptor antagonist. J Endocrinol. 1998 ; 159 (3). 519-526
33. Kniss DA, Zimmerman PD, Garver CL, Fertel RH. Interleukin-1 receptor antagonist blocks interleukin-1-induced expression of cyclooxygenase-2 in endometrium. Am J Obstet Gynecol. 1997 ; 177 (3). 559-567
34. Liong S, Di Quinzio MK, Heng YJ, et al. Proteomic analysis of human cervicovaginal fluid collected before preterm premature rupture of the fetal membranes. Reproduction. 2013 ; 145 (2). 137-147
35. Goldenberg RL, Iams JD, Mercer BM, et al. The preterm prediction study: toward a multiple-marker test for spontaneous preterm birth. Am J Obstet Gynecol. 2001 ; 185 (3). 643-651
36. Sanchez-Ramos L, Delke I, Zamora J, Kaunitz AM. Fetal fibronectin as a short-term predictor of preterm birth in symptomatic patients: a meta-analysis. Obstet Gynecol. 2009 ; 114 (3). 631-640
37. Ahner R, Kiss H, Egarter C, et al. Fetal fibronectin as a marker to predict the onset of term labor and delivery. Am J Obstet Gynecol. 1995 ; 172 (1 pt 1). 134-137
38. Ahner R, Kub-Csizi P, Heinzl H, et al. The fast-reacting fetal fibronectin test: a screening method for better prediction of the time of delivery. Am J Obstet Gynecol. 1997 ; 177 (6). 1478-1482
39. Mouw RJ, Egberts J, Kragt H, van Roosmalen J. Cervicovaginal fetal fibronectin concentrations: predictive value of impending birth in postterm pregnancies. Eur J Obstet Gynecol Reprod Biol. 1998 ; 80 (1). 67-70
40. Mouw RJ, Egberts J, van Roosmalen JJ, Kragt H. High cervical fetal-fibronectin concentrations and birth within 3 days in pregnancies of 41 weeks or more. N Engl J Med. 1995 ; 332 (16). 1105
41. Luton D, Guibourdenche J, Sibony O, et al. Fetal fibronectin in the cervical secretion predicts accurately the onset of labor at term. Eur J Obstet Gynecol Reprod Biol. 1997 ; 74 (2). 161-164
42. Donders GG, Vereecken A, Bosmans E, Spitz B. Vaginal cytokines in normal pregnancy. Am J Obstet Gynecol. 2003 ; 189 (5). 1433-1438
43. Agnew KJ, Aura J, Nunez N, et al. Effect of semen on vaginal fluid cytokines and secretory leukocyte protease inhibitor. Infect Dis Obstet Gynecol. 2008 ;: 820845
44. Leitich H, Egarter C, Kaider A, et al. Cervicovaginal fetal fibronectin as a marker for preterm delivery: a meta-analysis. Am J Obstet Gynecol. 1999 ; 180 (5). 1169-1176
45. Kekki M, Kurki T, Kärkkäinen T, Hiilesmaa V, Paavonen J, Rutanen EM. Insulin-like growth factor-binding protein-1 in cervical secretion as a predictor of preterm delivery. Acta Obstet Gynecol Scand. 2001 ; 80 (6). 546-551