Interleukin-1 receptor antagonist in human cervicovaginal fluid in term pregnancy and labor

American Journal of Obstetrics and Gynecology

Volumn 199, Issue 6, 2008, Pages 656.e1-656.e7

  Heng, Yujing J ^a,b   Di Quinzio, Megan K W ^a,b   Permezel, Michael ^a,b   Rice, Gregory E ^a,c   Georgiou, Harry M ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MERCY HOSPITAL FOR WOMEN   (Australia)

^c BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

biomarker; cervicovaginal fluid; interleukin 1 receptor antagonist; pregnancy; term labor

Indexed keywords

INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; LABOR; MICROBIAL ACTIVITY; NORMAL HUMAN; PREGNANCY; PRIORITY JOURNAL; SEXUAL BEHAVIOR; UTERINE CERVIX CYTOLOGY; VAGINA DISCHARGE;

EID: 57149147279     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2008.06.011     Document Type: Article

References (40)

1. Norwitz E.R., Robinson J.N., and Challis J.R. The control of labor. N Engl J Med 341 (1999) 660-666
2. Liggins G.C. Cervical ripening as an inflammatory reaction. In: Ellwood D.A., Andersonz A.B.M., and Embrey M.P. (Eds). The cervix in pregnancy and labour (1989), Churchill-Livingstone, Edinburgh
3. Thomson A.J., Telfer J.F., Young A., et al. Leukocytes infiltrate the myometrium during human parturition: further evidence that labour is an inflammatory process. Hum Reprod 14 (1999) 229-236
4. Osman I., Young A., Ledingham M., et al. Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term. Mol Hum Reprod 9 (2003) 41-45
5. Haddad R., Tromp G., Kuivaniemi H., et al. Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am J Obstet Gynecol 195 (2006) e1-e24
6. Keelan J.A., Marvin K.W., Sato T.A., Coleman M., McCowan L.M., and Mitchell M.D. Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition. Am J Obstet Gynecol 181 (1999) 1530-1536
7. Romero R., Brody D., Oyarzun E., et al. Infection and labor III. Interleukin-1: a signal for the onset of parturition. Am J Obstet Gynecol 160 (1989) 1117-1123
8. Rice G.E. Cytokines and the initiation of parturition. Front Horm Res 27 (2001) 113-146
9. López Bernal A., Rivera J., Reurope-Finner G.N., Phaneuf S., and Asboth G. Parturition: activation of stimulatory pathways or loss of uterine quiescence?. Adv Exp Med Biol 395 (1995) 435-451
10. Arend W.P., Malyak M., Guthridge C.J., and Gabay C. Interleukin-1 receptor antagonist: role in biology. Annu Rev Immunol 16 (1998) 27-55
11. Romero R., Gomez R., Galasso M., et al. The natural interleukin-1 receptor antagonist in the fetal, maternal, and amniotic fluid compartments: the effect of gestational age, fetal gender, and intrauterine infection. Am J Obstet Gynecol 171 (1994) 912-921
12. Fidel Jr. P.L., Romero R., Ramirez M., et al. Interleukin-1 receptor antagonist (IL-1ra) production by human amnion, chorion, and decidua. Am J Reprod Immunol 32 (1994) 1-7
13. Brown N.L., Alvi S.A., Elder M.G., Bennett P.R., and Sullivan M.H. Regulation of prostaglandin production in intact fetal membranes by interleukin-1 and its receptor antagonist. J Endocrinol 159 (1998) 519-526
14. Romero R., Sepulveda W., Mazor M., et al. The natural interleukin-1 receptor antagonist in term and preterm parturition. Am J Obstet Gynecol 167 (1992) 863-872
15. Baergen R., Benirschke K., and Ulich T. Cytokine expression in the placenta. Arch Pathol Lab Med 118 (1994) 52-55
16. Doh K., Barton P.T., Korneeva I., et al. Differential vaginal expression of interleukin-1 system cytokines in the presence of Mycoplasma hominis and Ureaplasma urealyticum in pregnant women. Infect Dis Obstet Gynecol 12 (2004) 79-85
17. Barton P.T., Gerber S., Skupski D.W., and Witkin S.S. Interleukin-1 receptor antagonist gene polymorphism, vaginal interleukin-1 receptor antagonist concentrations, and vaginal Ureaplasma urealyticum colonization in pregnant women. Infect Immun 71 (2003) 271-274
18. Di Quinzio M.K., Georgiou H.M., Holdsworth-Carson S.J., et al. Proteomic analysis of human cervico-vaginal fluid displays differential protein expression in association with labor onset at term. J Proteome Res 7 (2008) 1916-1921
19. Di Quinzio M.K., Oliva K., Holdsworth S.J., et al. Proteomic analysis and characterisation of human cervico-vaginal fluid proteins. Aust N Z J Obstet Gynaecol 47 (2007) 9-15
20. Tanaka Y., Narahara H., Takai N., Yoshimatsu J., Anai T., and Miyakawa I. Interleukin-1beta and interleukin-8 in cervicovaginal fluid during pregnancy. Am J Obstet Gynecol 179 (1998) 644-649
21. Imai M., Tani A., Saito M., Saito K., Amano K., and Nisijima M. Significance of fetal fibronectin and cytokine measurement in the cervicovaginal secretions of women at term in predicting term labor and post-term pregnancy. Eur J Obstet Gynaecol Reprod Biol 97 (2001) 53-58
22. Cox S.M., King M.R., Casey M.L., and MacDonald P.C. Interleukin-1 beta, -1 alpha, and -6 and prostaglandins in vaginal/cervical fluids of pregnant women before and during labor. J Clin Endocrinol Metab 77 (1993) 805-815
23. Ämmälä M., Nyman T., Salmi A., and Rutanen E.M. The interleukin-1 system in gestational tissues at term: effect of labour. Placenta 18 (1997) 717-723
24. Laham N., Brennecke S.P., Bendtzen K., and Rice G.E. Labour-associated increase in interleukin-1 alpha release in vitro by human gestational tissues. J Endocrinol 150 (1996) 515-522
25. Opsjøn S.L., Wathen N.C., Tingulstad S., et al. Tumor necrosis factor, interleukin-1, and interleukin-6 in normal human pregnancy. Am J Obstet Gynecol 169 (1993) 397-404
26. Romero R., Mazor M., Brandt F., et al. Interleukin-1 alpha and interleukin-1 beta in preterm and term human parturition. Am J Reprod Immunol 27 (1992) 117-123
27. Romero R., Parvizi S.T., Oyarzun E., et al. Amniotic fluid interleukin-1 in spontaneous labor at term. J Reprod Med 35 (1990) 235-238
28. Markovic D., Vatish M., Gu M., et al. The onset of labor alters corticotropin-releasing hormone type 1 receptor variant expression in human myometrium: putative role of interleukin-1 beta. Endocrinology 148 (2007) 3205-3213
29. Watari M., Watari H., DiSanto M.E., Chacko S., Shi G.P., and Strauss III J.F. Pro-inflammatory cytokines induce expression of matrix-metabolizing enzymes in human cervical smooth muscle cells. Am J Pathol 154 (1999) 1755-1762
30. 2 pathway in cultured human cervical fibroblasts. Mol Hum Reprod 9 (2003) 1-8
31. Moore R.M., Mansour J.M., Redline R.W., Mercer B.M., and Moore J.J. The physiology of fetal membrane rupture: Insight gained from the determination of physical properties. Placenta 27 (2006) 1037-1051
32. McLaren J., Malak T.M., and Bell S.C. Structural characteristics of term human fetal membranes before labour: identification of an area of altered morphology overlying the cervix. Hum Reprod 14 (1999) 237-241
33. Reti N.G., Lappas M., Riley C., et al. Why do membranes rupture at term?. Evidence of increased cellular apoptosis in the supracervical fetal membranes. Am J Obstet Gynecol 196 (2007) 484.e1-484.e10
34. El Khwad M., Pandey V., Stetzer B., Mercer B., Kumar D., and Moore R.M. Fetal membranes from term vaginal deliveries have a zone of weakness exhibiting characteristics of apoptosis and remodeling. J Soc Gynecol Invest 14 (2006) 191-195
35. Fortunato S.J., and Menon R. IL-1 beta is a better inducer of apoptosis in human fetal membranes than IL-6. Placenta 24 (2003) 922-928
36. Kumar D., Fung W., Moore R.M., et al. Proinflammatory cytokines found in amniotic fluid induce collagen remodeling, apoptosis, and biophysical weakening of cultured human fetal membranes. Biol Reprod 74 (2006) 29-34
37. Genc M., Witkin S.S., Delaney M., et al. A disproportionate increase in IL-1 beta over interleukin-1ra in the cervicovaginal secretions of pregnancy women with altered vaginal microflora correlates with preterm birth. Am J Obstet Gynecol 190 (2004) 1191-1197
38. Wang E.E., Matlow A.G., Ohlsson A., and Nelson S. Ureaplasma urealyticum infections in the perinatal period. Clin Perinatol 24 (1997) 91-105
39. Norwitz E.R., Snegovskikh V.V., and Caughey A.B. Prolonged pregnancy: when should we intervene?. Clin Obstet Gynecol 50 (2007) 547-557
40. Kiss H., Ahner R., Hohlagschwandtner M., Leitich H., and Husslein P. Fetal fibronectin as a predictor of term labor: a literature review. Acta Obstet Gynecol Scand 79 (2000) 3-7