Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome: A prospective multicentre study

Intensive Care Medicine

Volumn 39, Issue 5, 2013, Pages 899-909

  Reintam Blaser, Annika ^a   Poeze, Martijn ^b   Malbrain, Manu L N G ^c   Björck, Martin ^d   Oudemans Van Straaten, Heleen M ^e   Starkopf, Joel ^a  

^a TARTU UNIVERSITY HOSPITAL   (Estonia)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ZiekenhuisNetwerk Antwerpen   (Belgium)

^d UPPSALA UNIVERSITY   (Sweden)

^e Onze Lieve Vrouwe Gasthuis ^*  (Netherlands)

Author keywords

Gastrointestinal dysfunction; Gastrointestinal symptoms; Intensive care; Outcome

Indexed keywords

ABDOMINAL PRESSURE; ADULT; AGED; APACHE; ARTICLE; ARTIFICIAL VENTILATION; CALORIC INTAKE; DIGESTIVE SYSTEM FUNCTION DISORDER; ENTERIC FEEDING; FEEDING; GASTROINTESTINAL SYMPTOM; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; INTRAABDOMINAL HYPERTENSION; MAJOR CLINICAL STUDY; MORTALITY; OUTCOME ASSESSMENT; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DATA INTERPRETATION, STATISTICAL; FEMALE; GASTROINTESTINAL DISEASES; HEALTH STATUS INDICATORS; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; RISK FACTORS; TREATMENT OUTCOME;

EID: 84885023234     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-013-2831-1     Document Type: Article

References (27)

1. Montejo JC (1999) Enteral nutrition-related gastrointestinal complications in critically ill patients: a multicenter study: the Nutritional and Metabolic Working Group of the Spanish Society of Intensive Care Medicine and Coronary Units. Crit Care Med 27:1447-1453
2. Mutlu GM, Mutlu EA, Factor P (2001) GI complications in patients receiving mechanical ventilation. Chest 119:1222-1241
3. Mentec H, Dupont H, Bocchetti M, Cani P, Ponche F, Bleichner G (2001) Upper digestive intolerance during enteral nutrition in critically ill patients: frequency, risk factors, and complications. Crit Care Med 29:1955-1961
4. Reintam A, Parm P, Kitus R, Kern H, Starkopf J (2009) Gastrointestinal symptoms in intensive care patients. Acta Anaesthesiol Scand 53:318-324
5. Carrico CJ, Meakins JL, Marshall JC, Fry D, Maier RV (1986) Multiple-organ-failure syndrome. Arch Surg 121:196-208
6. Clark JA, Coopersmith CM (2007) Intestinal crosstalk: a new paradigm for understanding the gut as the "motor" of critical illness. Shock 28:384-393
7. Reintam Blaser A, Malbrain ML, Starkopf J, Fruhwald S, Jakob SM, De Waele J, Braun JP, Poeze M, Spies C (2012) Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on abdominal problems. Intensive Care Med 38:384-394
8. Vincent JL, Moreno R, Takala J, Willatts S, De Mendonca A, Bruining H, Reinhart CK, Suter PM, Thijs LG (1996) The SOFA (sepsis-related organ failure assessment) score to describe organ dysfunction/failure. Intensive Care Med 22:707-710
9. Reintam A, Parm P, Kitus R, Starkopf J, Kern H (2008) Gastrointestinal failure score in critically ill patients: a prospective observational study. Crit Care 12:R90
10. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101:1644-1655
11. Knaus WA, Draper EA, Wagner DP, Zimmerman JE (1985) APACHE II: a severity of disease classification system. Crit Care Med 13:818-829
12. Malbrain ML, Cheatham ML, Kirkpatrick A, Sugrue M, Parr M, De Waele J, Balogh Z, Leppaniemi A, Olvera C, Ivatury R, D'Amours S, Wendon J, Hillman K, Johansson K, Kolkman K, Wilmer A (2006) Results from the international conference of experts on intra-abdominal hypertension and abdominal compartment syndrome. I. Definitions. Intensive Care Med 32:1722-1732
13. McClave SA, Martindale RG, Vanek VW, McCarthy M, Roberts P, Taylor B, Ochoa JB, Napolitano L, Cresci G, ASPEN Board of Directors, American College of Critical Care Medicine, Society of Critical Care Medicine (2009) Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (ASPEN). JPEN J Parenter Enteral Nutr 33:277-316
14. Dalfino L, Tullo L, Donadio I, Malcangi V, Brienza N (2008) Intra-abdominal hypertension and acute renal failure in critically ill patients. Intensive Care Med 34:707-713
15. Malbrain ML, Chiumello D, Pelosi P, Bihari D, Innes R, Ranieri VM, Del Turco M, Wilmer A, Brienza N, Malcangi V, Cohen J, Japiassu A, De Keulenaer BL, Daelemans R, Jacquet L, Laterre PF, Frank G, de Souza P, Cesana B, Gattinoni L (2005) Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: a multiple-center epidemiological study. Crit Care Med 33:315-322
16. Kim IB, Prowle J, Baldwin I, Bellomo R (2012) Incidence, risk factors and outcome associations of intra-abdominal hypertension in critically ill patients. Anaesth Intensive Care 40:79-89
17. Ferreira FL, Bota DP, Bross A, Mélot C, Vincent JL (2001) Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA 286:1754-1758
18. Timsit JF, Fosse JP, Troché G, De Lassence A, Alberti C, Garrouste-Orgeas M, Bornstain C, Adrie C, Cheval C, Chevret S, OUTCOMEREA Study Group, France (2002) Calibration and discrimination by daily logistic organ dysfunction scoring comparatively with daily sequential organ failure assessment scoring for predicting hospital mortality in critically ill patients. Crit Care Med 30:2003-2013
19. Peres Bota D, Mélot C, Lopes Ferreira F, Nguyen BV, Vincent JL (2002) The multiple organ dysfunction score (MODS) versus the sequential organ failure assessment (SOFA) score in outcome prediction. Intensive Care Med 28:1619-1624
20. Gatt M, MacFie J, McNaughton L et al (2007) Gut function is an independent indicator of patient outcome: proof of principle. Clin Nutr 2(Suppl 2):108
21. Kreymann KG, Berger MM, Deutz NE, Hiesmayr M, Jolliet P, Kazandjiev G, Nitenberg G, van den Berghe G, Wernerman J, DGEM (German Society for Nutritional Medicine), Ebner C, Hartl W, Heymann C, Spies C, ESPEN (European Society for Parenteral and Enteral Nutrition) (2006) ESPEN guidelines on enteral nutrition: intensive care. Clin Nutr 25:210-223
22. Casaer MP, Mesotten D, Hermans G, Wouters PJ, Schetz M, Meyfroidt G, Van Cromphaut S, Ingels C, Meersseman P, Muller J, Vlasselaers D, Debaveye Y, Desmet L, Dubois J, Van Assche A, Vanderheyden S, Wilmer A, Van den Berghe G (2011) Early versus late parenteral nutrition in critically ill adults. N Engl J Med 365(6):506-517
23. Rice TW, Mogan S, Hays MA, Bernard GR, Jensen GL, Wheeler AP (2011) Randomized trial of initial trophic versus full-energy enteral nutrition in mechanically ventilated patients with acute respiratory failure. Crit Care Med 39:967-974
24. Heyland DK, Cahill N, Day AG (2011) Optimal amount of calories for critically ill patients: depends on how you slice the cake! Crit Care Med 39:2619-2626
25. Piton G, Manzon C, Cypriani B, Carbonnel F, Capellier G (2011) Acute intestinal failure in critically ill patients: is plasma citrulline the right marker? Intensive Care Med 37:911-917
26. Noordally SO, Sohawon S, Semlali H, Michely D, Devriendt J, Gottignies P (2012) Is there a correlation between circulating levels of citrulline and intestinal dysfunction in the critically ill? Nutr Clin Pract 27:527-532
27. Antonelli M, Azoulay E, Bonten M, Chastre J, Citerio G, Conti G, De Backer D, Gerlach H, Hedenstierna G, Joannidis M, Macrae D, Mancebo J, Maggiore SM, Mebazaa A, Preiser JC, Pugin J, Wernerman J, Zhang H (2011) Year in review in Intensive Care Medicine 2010: II. Pneumonia and infections, cardiovascular and haemodynamics, organization, education, haematology, nutrition, ethics and miscellanea. Intensive Care Med 37:196-213