Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice

Journal of Cerebral Blood Flow and Metabolism

Volumn 33, Issue 10, 2013, Pages 1605-1611

  Lin, Ai Ling ^a,b   Pulliam, Daniel A ^a,b   Deepa, Sathyaseelan S ^a,b   Halloran, Jonathan J ^a,b   Hussong, Stacy A ^a,b   Burbank, Raquel R ^a,b   Bresnen, Andrew ^a   Liu, Yuhong ^a,b   Podlutskaya, Natalia ^a,b   Soundararajan, Anuradha ^a   Muir, Eric ^a   Duong, Timothy Q ^a,b   Bokov, Alex F ^a,b   Viscomi, Carlo ^c   Zeviani, Massimo ^c   Richardson, Arlan G ^a,b,d   Van Remmen, Holly ^a,b,d   Fox, Peter T ^a,b   Galvan, Veronica ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

^d SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

glucose metabolism; memory; mitochondrial complex IV; mitochondrial dysfunction; Surf1

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIC AMP; CYTOCHROME C OXIDASE; GLUCOSE; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTIC ACID; PROTEIN; SURF1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN FUNCTION; BRAIN METABOLISM; BRAIN MITOCHONDRION; BREATHING; CELL FUNCTION; CONTROLLED STUDY; ENZYME ACTIVITY; FUNCTIONAL NEUROIMAGING; GLUCOSE BRAIN LEVEL; GLUCOSE METABOLISM; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMORY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; BEHAVIOR, ANIMAL; BLOOD FLOW VELOCITY; BRAIN; CEREBROVASCULAR CIRCULATION; GLUCOSE; HYDROGEN PEROXIDE; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MAZE LEARNING; MEMBRANE PROTEINS; MEMORY; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXYGEN CONSUMPTION;

EID: 84885020210     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2013.116     Document Type: Article

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