Intraocular growth factors and cytokines in patients with dry and neovascular age-related macular degeneration

Retina

Volumn 33, Issue 9, 2013, Pages 1809-1814

  Muether, Philipp S ^a   Neuhann, Irmingard ^b   Buhl, Christoph ^a   Hermann, Manuel M ^a   Kirchhof, Bernd ^a   Fauser, Sascha ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b Gynecological Hospital Red Cross   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIN; CYTOKINE; ENDOSTATIN; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; PLACENTAL GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR AA; THROMBOSPONDIN 2; VASCULOTROPIN; VASCULOTROPIN INHIBITOR;

AGED; AQUEOUS HUMOR; ARTICLE; ASSAY; CATARACT EXTRACTION; CLINICAL AGE RELATED MACULOPATHY STAGING SYSTEM; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; PROSPECTIVE STUDY; RETINA MACULA AGE RELATED DEGENERATION; RETINA NEOVASCULARIZATION;

EID: 84885018646     PISSN: 0275004X     EISSN: 15392864     Source Type: Journal    
DOI: 10.1097/IAE.0b013e318285cd9e     Document Type: Article

References (25)

1. Augood C, Fletcher A, Bentham G, et al. Methods for a population-based study of the prevalence of and risk factors for age-related maculopathy and macular degeneration in elderly European populations: the EUREYE study. Ophthalmic Epidemiol 2004;11:117-129. (Pubitemid 38530466)
2. Bressler NM. Age-related macular degeneration is the leading cause of blindness. JAMA 2004;291:1900-1901. (Pubitemid 38509505)
3. Ferris FL III, Fine SL, Hyman L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol 1984;102:1640-1642. (Pubitemid 15204559)
4. Friedman DS, O'Colmain BJ, Munoz B, et al. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 2004;122:564-572. (Pubitemid 38456293)
5. Resnikoff S, Pascolini D, Etya'ale D, et al. Global data on visual impairment in the year 2002. Bull World Health Organ 2004;82:844-851.
6. Kvanta A, Algvere PV, Berglin L, Seregard S. Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor. Invest Ophthalmol Vis Sci 1996;37:1929-1934. (Pubitemid 26324159)
7. Holekamp NM, Bouck N, Volpert O. Pigment epitheliumderived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration. Am J Ophthalmol 2002;134:220-227. (Pubitemid 34831826)
8. Jonas JB, Tao Y, Neumaier M, Findeisen P. Monocyte chemoattractant protein 1, intercellular adhesion molecule 1, and vascular cell adhesion molecule 1 in exudative age-related macular degeneration. Arch Ophthalmol 2010;128:1281-1286.
9. Roh MI, Kim HS, Song JH, et al. Concentration of cytokines in the aqueous humor of patients with naive, recurrent and regressed CNV associated with AMD after bevacizumab treatment. Retina 2009;29:523-529.
10. Funk M, Karl D, Georgopoulos M, et al. Neovascular agerelated macular degeneration: intraocular cytokines and growth factors and the influence of therapy with ranibizumab. Ophthalmology 2009;116:2393-2399.
11. Tong JP, Chan WM, Liu DT, et al. Aqueous humor levels of vascular endothelial growth factor and pigment epithelium-derived factor in polypoidal choroidal vasculopathy and choroidal neovascularization. Am J Ophthalmol 2006;141:456-462. (Pubitemid 43265948)
12. Funatsu H, Yamashita H, Noma H, et al. Aqueous humor levels of cytokines are related to vitreous levels and progression of diabetic retinopathy in diabetic patients. Graefes Arch Clin Exp Ophthalmol 2005;243:3-8.
13. de Oliveira Dias JR, Rodrigues EB, Maia M, et al. Cytokines in neovascular age-related macular degeneration: fundamentals of targeted combination therapy. Br J Ophthalmol 2011;95: 1631-1637.
14. Rakic JM, Lambert V, Devy L, et al. Placental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization. Invest Ophthalmol Vis Sci 2003;44:3186-3193. (Pubitemid 36759791)
15. Otani A, Takagi H, Oh H, et al. Vascular endothelial growth factor family and receptor expression in human choroidal neovascular membranes. Microvasc Res 2002;64:162-169. (Pubitemid 34713242)
16. Hu W, Criswell MH, Fong SL, et al. Differences in the temporal expression of regulatory growth factors during choroidal neovascular development. Exp Eye Res 2009;88:79-91.
17. Marneros AG, She H, Zambarakji H, et al. Endogenous endostatin inhibits choroidal neovascularization. FASEB J 2007;21: 3809-3818. (Pubitemid 350232338)
18. Tatar O, Shinoda K, Adam A, et al. Expression of endostatin in human choroidal neovascular membranes secondary to agerelated macular degeneration. Exp Eye Res 2006;83:329-338. (Pubitemid 43850949)
19. Skeie JM, Zeng S, Faidley EA, Mullins RF. Angiogenin in age-related macular degeneration. Mol Vis 2011;17:576-582.
20. Bird AC, Bressler NM, Bressler SB, et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol 1995;39:367-374.
21. Seddon JM, Sharma S, Adelman RA. Evaluation of the clinical age-related maculopathy staging system. Ophthalmology 2006; 113:260-266. (Pubitemid 43170775)
22. Wang S, Sorenson CM, Sheibani N. Lack of thrombospondin 1 and exacerbation of choroidal neovascularization. Arch Ophthalmol 2012;130:615-620.
23. Bhutto IA, Uno K, Merges C, et al. Reduction of endogenous angiogenesis inhibitors in Bruch's membrane of the submacular region in eyes with age-related macular degeneration. Arch Ophthalmol 2008;126:670-678. (Pubitemid 351679563)
24. Dell'omo R, Cassetta M, Dell'omo E, et al. Aqueous humor levels of vascular endothelial growth factor before and after intravitreal bevacizumab in type 3 versus type 1 and 2 neovascularization. A prospective, case-control study. Am J Ophthalmol 2012;153:155-161.e152.
25. Buschini E, Piras A, Nuzzi R, Vercelli A. Age related macular degeneration and drusen: neuroinflammation in the retina. Prog Neurobiol 2011;95:14-25.