Fetal Mesenchymal Stromal Cells From Cryopreserved Human Chorionicvilli: Cytogenetic And Molecular Analysis Of Genome Stability In Long-Term Cultures

Cytotherapy

Volumn 15, Issue 11, 2013, Pages 1340-1351

  Roselli, Emanuela Anna ^a   Lazzati, Silvia ^a   Iseppon, Federico ^a   Manganini, Massimiliano ^b   Marcato, Livia ^a   Gariboldi, Marzia Bruna ^c   Maggi, Federico ^a   Grati, Francesca Romana ^a   Simoni, Giuseppe ^a,b  

^a TOMA Advanced Biomedical Assays SpA   (Italy)

^b Biocell Center SpA   (Italy)

^c UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Array comparative genomic hybridization; Chorionic villi; Genomic instability; Human placenta; Mesenchymal stromal cells

Indexed keywords

DNA;

ANEUPLOIDY; ARTICLE; CELL EXPANSION; CELL ISOLATION; CELL THERAPY; CHORION VILLUS; CHROMOSOME ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; CRYOPRESERVATION; CULTURE TECHNIQUE; FETUS; FETUS CELL; GENETIC VARIABILITY; GENOMIC INSTABILITY; GENOTYPE; GOOD MANUFACTURING PRACTICE; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KARYOTYPE; LONG TERM CULTURE; MESENCHYMAL STROMA CELL; PRIORITY JOURNAL; REGENERATIVE MEDICINE;

ARRAY-COMPARATIVE GENOMIC HYBRIDIZATION; CHORIONIC VILLI; GENOMIC INSTABILITY; HUMAN PLACENTA; MESENCHYMAL STROMAL CELLS;

ADIPOCYTES; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL- AND TISSUE-BASED THERAPY; CELLS, CULTURED; CHONDROCYTES; CHORIONIC VILLI; COMPARATIVE GENOMIC HYBRIDIZATION; CRYOPRESERVATION; FEMALE; GENETIC VARIATION; GENOMIC INSTABILITY; HUMANS; IMMUNOPHENOTYPING; MESENCHYMAL STROMAL CELLS; MICROSATELLITE REPEATS; OSTEOCYTES; PREGNANCY; PREGNANCY TRIMESTER, FIRST; TISSUE ENGINEERING;

EID: 84884924518     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2013.06.019     Document Type: Article

References (51)

1. Bajada S., Mazakova I., Richardson J.B., Ashammakhi N. Updates on stem cells and their applications in regenerative medicine. JTissue Eng Regen Med 2008, 2:169-183.
2. Lanfranchi A., Porta F., Chirico G. Stem cells and the frontiers of neonatology. Early Hum Dev 2009, 85(Suppl 10):S15-S18.
3. Ankrum J., Karp J.M. Mesenchymal stem cell therapy: two steps forward, one step back. Trends Mol Med 2010, 16:203-209.
4. Dominici M., Le Blanc K., Mueller I., Slaper-Cortenbach I., Marini F., Krause D., et al. Minimal criteria for defining multipotent mesenchymal stromal cells: the International Society for Cellular Therapy position statement. Cytotherapy 2006, 8:315-317.
5. Le Blanc K., Ringden O. Mesenchymal stem cells: properties and role in clinical bone marrow transplantation. Curr Opin Immunol 2006, 18:586-591.
6. Pittenger M.F., Mackay A.M., Beck S.C., Jaiswal R.K., Douglas R., Mosca J.D., et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999, 284:143-147.
7. Mueller S.M., Glowacki J. Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges. JCell Biochem 2001, 82:583-590.
8. Fauza D. Amniotic fluid and placental stem cells. Best Pract Res Clin Obstet Gynaecol 2004, 18:877-891.
9. Li L., Zheng F.P., Wang G., Li H. Recurrent Hashimoto's encephalopathy, showing spontaneous remission: a case report. Intern Med 2011, 50:1309-1312.
10. Brambati B., Simoni G. Diagnosis of fetal trisomy 21 in first trimester. Lancet 1983, 1:586.
11. Castrechini N.M., Murthi P., Gude N.M., Erwich J.J., Gronthos S., Zannettino A., et al. Mesenchymal stem cells in human placental chorionic villi reside in a vascular niche. Placenta 2010, 31:203-212.
12. Wang Y., Han Z.B., Song Y.P., Han Z.C. Safety of mesenchymal stem cells for clinical application. Stem Cells Int 2012, 2012:652034.
13. Rosland G.V., Svendsen A., Torsvik A., Sobala E., McCormack E., Immervoll H., et al. Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation. Cancer Res 2009, 69:5331-5339.
14. Izadpanah R., Kaushal D., Kriedt C., Tsien F., Patel B., Dufour J., et al. Long-term in vitro expansion alters the biology of adult mesenchymal stem cells. Cancer Res 2008, 68:4229-4238.
15. Rubio D., Garcia-Castro J., Martin M.C., de la Fuente R., Cigudosa J.C., Lloyd A.C., et al. Spontaneous human adult stem cell transformation. Cancer Res 2005, 65:3035-3039.
16. Aguilar S., Nye E., Chan J., Loebinger M., Spencer-Dene B., Fisk N., et al. Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lung. Stem Cells 2007, 25:1586-1594.
17. Vilalta M., Degano I.R., Bago J., Gould D., Santos M., Garcia-Arranz M., et al. Biodistribution, long-term survival, and safety of human adipose tissue-derived mesenchymal stem cells transplanted in nude mice by high sensitivity non-invasive bioluminescence imaging. Stem Cells Dev 2008, 17:993-1003.
18. Bernardo M.E., Zaffaroni N., Novara F., Cometa A.M., Avanzini M.A., Moretta A., et al. Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms. Cancer Res 2007, 67:9142-9149.
19. Poloni A., Maurizi G., Babini L., Serrani F., Berardinelli E., Mancini S., et al. Human mesenchymal stem cells from chorionic villi and amniotic fluid are not susceptible to transformation after extensive in vitro expansion. Cell Transplant 2011, 20:643-654.
20. Sessarego N., Parodi A., Podesta M., Benvenuto F., Mogni M., Raviolo V., et al. Multipotent mesenchymal stromal cells from amniotic fluid: solid perspectives for clinical application. Haematologica 2008, 93:339-346.
21. Poloni A., Rosini V., Mondini E., Maurizi G., Mancini S., Discepoli G., et al. Characterization and expansion of mesenchymal progenitor cells from first-trimester chorionic villi of human placenta. Cytotherapy 2008, 10:690-697.
22. Kolquist K.A., Schultz R.A., Furrow A., Brown T.C., Han J.Y., Campbell L.J., et al. Microarray-based comparative genomic hybridization of cancer targets reveals novel, recurrent genetic aberrations in the myelodysplastic syndromes. Cancer Genet 2011, 204:603-628.
23. Elliott A.M., Elliott K.A., Kammesheidt A. Array-comparative genomic hybridization characterization of human pluripotent stem cells. Methods Mol Biol 2012, 873:261-267.
24. Tsai M.S., Lee J.L., Chang Y.J., Hwang S.M. Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol. Hum Reprod 2004, 19:1450-1456.
25. Alviano F., Fossati V., Marchionni C., Arpinati M., Bonsi L., Franchina M., et al. Term amniotic membrane is a high throughput source for multipotent mesenchymal stem cells with the ability to differentiate into endothelial cells in vitro. BMC Dev Biol 2007, 7:11.
26. Shaffer L.G., Bejjani B.A. Using microarray-based molecular cytogenetic methods to identify chromosome abnormalities. Pediatr Ann 2009, 38:440-447.
27. Karger B.L., Guttman A. DNA sequencing by CE. Electrophoresis 2009, 30(Suppl 1):S196-S202.
28. Mann K. Prenatal detection of chromosome aneuploidy by quantitative fluorescence-PCR. Methods Mol Med 2004, 92:141-156.
29. Ogilvie C.M., Donaghue C., Fox S.P., Docherty Z., Mann K. Rapid prenatal diagnosis of aneuploidy using quantitative fluorescence-PCR (QF-PCR). JHistochem Cytochem 2005, 53:285-288.
30. Mann K., Donaghue C., Ogilvie C.M. In vivo somatic microsatellite mutations identified in non-malignant human tissue. Hum Genet 2003, 114:110-114.
31. Boland C.R., Thibodeau S.N., Hamilton S.R., Sidransky D., Eshleman J.R., Burt R.W., et al. ANational Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998, 58:5248-5257.
32. Parolini O., Alviano F., Bagnara G.P., Bilic G., Buhring H.J., Evangelista M., et al. Concise review: isolation and characterization of cells from human term placenta: outcome of the first international Workshop on Placenta Derived Stem Cells. Stem Cells 2008, 26:300-311.
33. In't Anker P.S., Scherjon S.A., Kleijburg-van der Keur C., de Groot-Swings G.M., Claas F.H., Fibbe W.E., et al. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells 2004, 22:1338-1345.
34. Portmann-Lanz C.B., Schoeberlein A., Huber A., Sager R., Malek A., Holzgreve W., et al. Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration. Am J Obstet Gynecol 2006, 194:664-673.
35. Ilancheran S., Michalska A., Peh G., Wallace E.M., Pera M., Manuelpillai U. Stem cells derived from human fetal membranes display multilineage differentiation potential. Biol Reprod 2007, 77:577-588.
36. Chien C.C., Yen B.L., Lee F.K., Lai T.H., Chen Y.C., Chan S.H., et al. In vitro differentiation of human placenta-derived multipotent cells into hepatocyte-like cells. Stem Cells 2006, 24:1759-1768.
37. Tamagawa T., Oi S., Ishiwata I., Ishikawa H., Nakamura Y. Differentiation of mesenchymal cells derived from human amniotic membranes into hepatocyte-like cells in vitro. Hum Cell 2007, 20:77-84.
38. Zhao P., Ise H., Hongo M., Ota M., Konishi I., Nikaido T. Human amniotic mesenchymal cells have some characteristics of cardiomyocytes. Transplantation 2005, 79:528-535.
39. Miao Z., Jin J., Chen L., Zhu J., Huang W., Zhao J., et al. Isolation of mesenchymal stem cells from human placenta: comparison with human bone marrow mesenchymal stem cells. Cell Biol Int 2006, 30:681-687.
40. Yen B.L., Chien C.C., Chen Y.C., Chen J.T., Huang J.S., Lee F.K., et al. Placenta-derived multipotent cells differentiate into neuronal and glial cells in vitro. Tissue Eng Part A 2008, 14:9-17.
41. Wapner R.J. What can we expect from invasive procedures in 10 years time?. Prenat Diagn 2010, 30:704-705.
42. Igura K., Zhang X., Takahashi K., Mitsuru A., Yamaguchi S., Takashi T.A. Isolation and characterization of mesenchymal progenitor cells from chorionic villi of human placenta. Cytotherapy 2004, 6:543-553.
43. Park S., Koh S.E., Maeng S., Lee W.D., Lim J., Lee Y.J. Neural progenitors generated from the mesenchymal stem cells of first-trimester human placenta matured in the hypoxic-ischemic rat brain and mediated restoration of locomotor activity. Placenta 2011, 32:269-276.
44. Prockop D.J., Brenner M., Fibbe W.E., Horwitz E., Le Blanc K., Phinney D.G., et al. Defining the risks of mesenchymal stromal cell therapy. Cytotherapy 2010, 12:576-578.
45. Ra J.C., Kang S.K., Shin I.S., Park H.G., Joo S.A., Kim J.G., et al. Stem cell treatment for patients with autoimmune disease bysystemic infusion of culture-expanded autologous adiposetissue derived mesenchymal stem cells. JTransl Med 2011, 9:181.
46. Kim J., Kang J.W., Park J.H., Choi Y., Choi K.S., Park K.D., et al. Biological characterization of long-term cultured human mesenchymal stem cells. Arch Pharm Res 2009, 32:117-126.
47. Philippe B., Luc S., Valerie P.B., Jerome R., Alessandra B.R., Louis C. Culture and use of mesenchymal stromal cells in phase I and II clinical trials. Stem Cells Int 2010, 2010:503593.
48. Tarte K., Gaillard J., Lataillade J.J., Fouillard L., Becker M., Mossafa H., et al. Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation. Blood 2010, 115:1549-1553.
49. Redaelli S., Bentivegna A., Foudah D., Miloso M., Redondo J., Riva G., et al. From cytogenomic to epigenomic profiles: monitoring the biologic behavior of in vitro cultured human bone marrow mesenchymal stem cells. Stem Cell Res Ther 2012, 3:47.
50. Bork S., Pfister S., Witt H., Horn P., Korn B., Ho A.D., et al. DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells. Aging Cell 2010, 9:54-63.
51. Schellenberg A., Lin Q., Schuler H., Koch C.M., Joussen S., Denecke B., et al. Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks. Aging 2011, 3:873-888.