Paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels

Fertility and Sterility

Volumn 100, Issue 4, 2013, Pages

  Jenkins, Timothy G ^a   Aston, Kenneth I ^a   Cairns, Bradley R ^a   Carrell, Douglas T ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

5 hydroxymethylcytosine; 5 methylcytosine; Advanced paternal; age global DNA methylation; sperm DNA methylation

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE;

AGING; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DNA EXTRACTION; DNA METHYLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FERTILIZATION IN VITRO; HUMAN; MALE; MEASUREMENT; MICROARRAY ANALYSIS; PATERNAL AGE; PRIORITY JOURNAL; SEMEN ANALYSIS; SPERM DONOR;

5-HYDROXYMETHYLCYTOSINE; 5-METHYLCYTOSINE; ADVANCED PATERNAL AGE; GLOBAL DNA METHYLATION; SPERM DNA METHYLATION;

5-METHYLCYTOSINE; ADULT; AGE FACTORS; AGING; CYTOSINE; DNA; DNA METHYLATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MALE; MIDDLE AGED; PATERNAL AGE; PROSPECTIVE STUDIES; RISK FACTORS; SPERMATOZOA; UP-REGULATION;

EID: 84884906522     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.05.039     Document Type: Article

References (23)

1. J. Balasch, and E. Gratacos Delayed childbearing: effects on fertility and the outcome of pregnancy Fetal Diagn Ther 29 2011 263 273
2. I.D. van Balkom, M. Bresnahan, P.J. Vuijk, J. Hubert, E. Susser, and H.W. Hoek Paternal age and risk of autism in an ethnically diverse, non-industrialized setting: Aruba PLoS One 7 2012 e45090
3. R.G. Smith, R.L. Kember, J. Mill, C. Fernandes, L.C. Schalkwyk, and J.D. Buxbaum Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model PLoS One 4 2009 e8456
4. M. Naserbakht, H.R. Ahmadkhaniha, B. Mokri, and C.L. Smith Advanced paternal age is a risk factor for schizophrenia in Iranians Ann Gen Psychiatry 10 2011 15
5. C. Dalman Advanced paternal age increases risk of bipolar disorder in offspring Evid Based Ment Health 12 2009 59
6. T.E. Schmid, B. Eskenazi, A. Baumgartner, F. Marchetti, S. Young, and R. Weldon The effects of male age on sperm DNA damage in healthy non-smokers Hum Reprod 22 2007 180 187 (Pubitemid 44942683)
7. A.J. Wyrobek, B. Eskenazi, S. Young, N. Arnheim, I. Tiemann-Boege, and E.W. Jabs Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm Proc Natl Acad Sci USA 103 2006 9601 9606 (Pubitemid 43955871)
8. Z. Wiener-Megnazi, R. Auslender, and M. Dirnfeld Advanced paternal age and reproductive outcome Asian J Androl 14 2012 69 76
9. A.P. Alio, H.M. Salihu, C. McIntosh, E.M. August, H. Weldeselasse, and E. Sanchez The effect of paternal age on fetal birth outcomes Am J Mens Health 6 2012 427 435
10. Y. Xiao, B. Word, A. Starlard-Davenport, A. Haefele, B.D. Lyn-Cook, and G. Hammons Age and gender affect DNMT3a and DNMT3b expression in human liver Cell Biol Toxicol 24 2008 265 272 (Pubitemid 351579713)
11. V.L. Wilson, and P.A. Jones DNA methylation decreases in aging but not in immortal cells Science 220 1983 1055 1057 (Pubitemid 13090144)
12. C.C. Oakes, D.J. Smiraglia, C. Plass, J.M. Trasler, and B. Robaire Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats Proc Natl Acad Sci USA 100 2003 1775 1780 (Pubitemid 36254524)
13. R.F. Thompson, G. Atzmon, C. Gheorghe, H.Q. Liang, C. Lowes, and J.M. Greally Tissue-specific dysregulation of DNA methylation in aging Aging Cell 9 2010 506 518
14. S.S. Hammoud, D.A. Nix, H. Zhang, J. Purwar, D.T. Carrell, and B.R. Cairns Distinctive chromatin in human sperm packages genes for embryo development Nature 460 2009 473 478
15. A. Arpanahi, M. Brinkworth, D. Iles, S.A. Krawetz, A. Paradowska, and A.E. Platts Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences Genome Res 19 2009 1338 1349
16. L. Nanassy, and D.T. Carrell Analysis of the methylation pattern of six gene promoters in sperm of men with abnormal protamination Asian J Androl 13 2011 342 346
17. P.M. Craig, and T.W. Moon Methionine restriction affects the phenotypic and transcriptional response of rainbow trout (Oncorhynchus mykiss) to carbohydrate-enriched diets Br J Nutr 2012 1 11
18. E. Quadros Vitamin B12 deficiency in the brain leads to DNA hypomethylation in the TCblR/CD320 knockout mouse Nutr Metab (Lond) 9 2012 41
19. T.C. Wang, Y.S. Song, H. Wang, J. Zhang, S.F. Yu, and Y.E. Gu Oxidative DNA damage and global DNA hypomethylation are related to folate deficiency in chromate manufacturing workers J Hazard Mater 213-214 2012 440 446
20. Y. Yamamura, K. Aota, T. Yamanoi, K. Kani, H. Takano, and Y. Momota DNA demethylating agent decitabine increases AQP5 expression and restores salivary function J Dent Res 91 2012 612 617
21. C.E. Nestor, R. Ottaviano, J. Reddington, D. Sproul, D. Reinhardt, and D. Dunican Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes Genome Res 22 2012 467 477
22. J. Barzideh, R.J. Scott, and R.J. Aitken Analysis of the global methylation status of human spermatozoa and its association with the tendency of these cells to enter apoptosis Andrologia 2012
23. C.X. Song, K.E. Szulwach, Y. Fu, Q. Dai, C. Yi, and X. Li Selective chemical labeling reveals the genome-wide distribution of 5- hydroxymethylcytosine Nat Biotechnol 29 2010 68 72