-
1
-
-
0024805137
-
Rodent models of cerebral ischemia
-
Ginsberg MD, Busto R. Rodent models of cerebral ischemia. Stroke. 1989;20: 1627-42.
-
(1989)
Stroke
, vol.20
, pp. 1627-1642
-
-
Ginsberg, M.D.1
Busto, R.2
-
2
-
-
0028959038
-
Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation
-
Garcia JH, Wagner S, Liu KF, Hu XJ. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke. 1995;26: 627-34.
-
(1995)
Stroke
, vol.26
, pp. 627-634
-
-
Garcia, J.H.1
Wagner, S.2
Liu, K.F.3
Hu, X.J.4
-
3
-
-
79955718269
-
Emerging therapies: pleiotropic multi-target drugs to treat stroke victims
-
Lapchak PA. Emerging therapies: pleiotropic multi-target drugs to treat stroke victims. Transl Stroke Res. 2011;2: 129-35.
-
(2011)
Transl Stroke Res.
, vol.2
, pp. 129-135
-
-
Lapchak, P.A.1
-
4
-
-
0037384802
-
Signaling of cell death and cell survival following focal cerebral ischemia: life and death struggle in the penumbra
-
Ferrer I, Planas AM. Signaling of cell death and cell survival following focal cerebral ischemia: life and death struggle in the penumbra. J Neuropathol Exp Neurol. 2003;62: 329-39.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 329-339
-
-
Ferrer, I.1
Planas, A.M.2
-
5
-
-
84861675228
-
Defining the ischemic penumbra using hyperacute neuroimaging: deriving quantitative ischemic thresholds
-
Ford AL, An H, Vo KD, Lin W, Lee JM. Defining the ischemic penumbra using hyperacute neuroimaging: deriving quantitative ischemic thresholds. Transl Stroke Res. 2012;3: 198-204.
-
(2012)
Transl Stroke Res.
, vol.3
, pp. 198-204
-
-
Ford, A.L.1
An, H.2
Vo, K.D.3
Lin, W.4
Lee, J.M.5
-
6
-
-
0038218405
-
Sphingosine-1-phosphate: an enigmatic signalling lipid
-
Spiegel S, Milstien S. Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol. 2003;4: 397-407.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
7
-
-
36549047503
-
Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis
-
Dev KK, Mullershausen F, Mattes H, Kuhn RR, Bilbe G, Hoyer D, et al. Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis. Pharmacol Ther. 2008;117: 77-93.
-
(2008)
Pharmacol Ther
, vol.117
, pp. 77-93
-
-
Dev, K.K.1
Mullershausen, F.2
Mattes, H.3
Kuhn, R.R.4
Bilbe, G.5
Hoyer, D.6
-
8
-
-
77449106966
-
Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats
-
Hasegawa Y, Suzuki H, Sozen T, Rolland W, Zhang JH. Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats. Stroke. 2010;41: 368-74.
-
(2010)
Stroke
, vol.41
, pp. 368-374
-
-
Hasegawa, Y.1
Suzuki, H.2
Sozen, T.3
Rolland, W.4
Zhang, J.H.5
-
9
-
-
79960672924
-
FTY720 is neuroprotective and improves functional outcomes after intracerebral hemorrhage in mice
-
Rolland II WB, Manaenko A, Lekic T, Hasegawa Y, Ostrowski R, Tang J, et al. FTY720 is neuroprotective and improves functional outcomes after intracerebral hemorrhage in mice. Acta Neurochir Suppl. 2011;111: 213-7.
-
(2011)
Acta Neurochir Suppl.
, vol.111
, pp. 213-217
-
-
Rolland II, W.B.1
Manaenko, A.2
Lekic, T.3
Hasegawa, Y.4
Ostrowski, R.5
Tang, J.6
-
10
-
-
84861527226
-
Isoflurane delays the development of early brain injury after subarachnoid hemorrhage through sphingosine-related pathway activation in mice
-
Altay O, Hasegawa Y, Sherchan P, Suzuki H, Khatibi NH, Tang J, et al. Isoflurane delays the development of early brain injury after subarachnoid hemorrhage through sphingosine-related pathway activation in mice. Crit Care Med. 2012;40: 1908-13.
-
(2012)
Crit Care Med
, vol.40
, pp. 1908-1913
-
-
Altay, O.1
Hasegawa, Y.2
Sherchan, P.3
Suzuki, H.4
Khatibi, N.H.5
Tang, J.6
-
11
-
-
77954177284
-
Isoflurane posttreatment reduces neonatal hypoxic-ischemic brain injury in rats by the sphingosine-1-phosphate/phosphatidylinositol-3-kinase/Akt pathway
-
Zhou Y, Lekic T, Fathali N, Ostrowski RP, Martin RD, Tang J, et al. Isoflurane posttreatment reduces neonatal hypoxic-ischemic brain injury in rats by the sphingosine-1-phosphate/phosphatidylinositol-3-kinase/Akt pathway. Stroke. 2010;41: 1521-7.
-
(2010)
Stroke
, vol.41
, pp. 1521-1527
-
-
Zhou, Y.1
Lekic, T.2
Fathali, N.3
Ostrowski, R.P.4
Martin, R.D.5
Tang, J.6
-
12
-
-
84869866480
-
Acute splenic irradiation reduces brain injury in the rat focal ischemic stroke model
-
Ostrowski RP, Schulte RW, Nie Y, Ling T, Lee T, Manaenko A, et al. Acute splenic irradiation reduces brain injury in the rat focal ischemic stroke model. Transl Stroke Res. 2012;3: 473-81.
-
(2012)
Transl Stroke Res.
, vol.3
, pp. 473-481
-
-
Ostrowski, R.P.1
Schulte, R.W.2
Nie, Y.3
Ling, T.4
Lee, T.5
Manaenko, A.6
-
13
-
-
0034733556
-
Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform
-
Liu H, Sugiura M, Nava VE, Edsall LC, Kono K, Poulton S, et al. Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform. J Biol Chem. 2000;275: 19513-20.
-
(2000)
J Biol Chem
, vol.275
, pp. 19513-19520
-
-
Liu, H.1
Sugiura, M.2
Nava, V.E.3
Edsall, L.C.4
Kono, K.5
Poulton, S.6
-
14
-
-
0025044655
-
Beam-walking in rats: studies towards developing an animal model of functional recovery after brain injury
-
Goldstein LB, Davis JN. Beam-walking in rats: studies towards developing an animal model of functional recovery after brain injury. J Neurosci Methods. 1990;31: 101-7.
-
(1990)
J Neurosci Methods.
, vol.31
, pp. 101-107
-
-
Goldstein, L.B.1
Davis, J.N.2
-
15
-
-
0022483434
-
Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination
-
Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke. 1986;17: 472-6.
-
(1986)
Stroke
, vol.17
, pp. 472-476
-
-
Bederson, J.B.1
Pitts, L.H.2
Tsuji, M.3
Nishimura, M.C.4
Davis, R.L.5
Bartkowski, H.6
-
16
-
-
33846811196
-
Regulation and functional roles of sphingosine kinases
-
Alemany R, van Koppen CJ, Danneberg K, Ter Braak M, Meyer Zu Heringdorf D. Regulation and functional roles of sphingosine kinases. Naunyn Schmiedebergs Arch Pharmacol. 2007;374: 413-28.
-
(2007)
Naunyn Schmiedebergs Arch Pharmacol.
, vol.374
, pp. 413-428
-
-
Alemany, R.1
van Koppen, C.J.2
Danneberg, K.3
Ter Braak, M.4
Meyer Zu Heringdorf, D.5
-
17
-
-
0033566208
-
Enzymatic measurement of sphingosine 1-phosphate
-
Edsall LC, Spiegel S. Enzymatic measurement of sphingosine 1-phosphate. Anal Biochem. 1999;272: 80-6.
-
(1999)
Anal Biochem
, vol.272
, pp. 80-86
-
-
Edsall, L.C.1
Spiegel, S.2
-
18
-
-
0037317807
-
Temporal profile of angiogenesis and expression of related genes in the brain after ischemia
-
Hayashi T, Noshita N, Sugawara T, Chan PH. Temporal profile of angiogenesis and expression of related genes in the brain after ischemia. J Cereb Blood Flow Metab. 2003;23: 166-80.
-
(2003)
J Cereb Blood Flow Metab
, vol.23
, pp. 166-180
-
-
Hayashi, T.1
Noshita, N.2
Sugawara, T.3
Chan, P.H.4
-
19
-
-
34848826331
-
Distribution of sphingosine kinase activity and mRNA in rodent brain
-
Blondeau N, Lai Y, Tyndall S, Popolo M, Topalkara K, Pru JK, et al. Distribution of sphingosine kinase activity and mRNA in rodent brain. J Neurochem. 2007;103: 509-17.
-
(2007)
J Neurochem
, vol.103
, pp. 509-517
-
-
Blondeau, N.1
Lai, Y.2
Tyndall, S.3
Popolo, M.4
Topalkara, K.5
Pru, J.K.6
-
20
-
-
58149345610
-
Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain
-
Kimura A, Ohmori T, Kashiwakura Y, Ohkawa R, Madoiwa S, Mimuro J, et al. Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain. Stroke. 2008;39: 3411-7.
-
(2008)
Stroke
, vol.39
, pp. 3411-3417
-
-
Kimura, A.1
Ohmori, T.2
Kashiwakura, Y.3
Ohkawa, R.4
Madoiwa, S.5
Mimuro, J.6
-
21
-
-
76149093586
-
A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis
-
Kappos L, Radue EW, O'Connor P, Polman C, Hohlfeld R, Calabresi P, et al. A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis. N Engl J Med. 2010;362: 387-401.
-
(2010)
N Engl J Med
, vol.362
, pp. 387-401
-
-
Kappos, L.1
Radue, E.W.2
O'Connor, P.3
Polman, C.4
Hohlfeld, R.5
Calabresi, P.6
-
22
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
-
Brinkmann V, Davis MD, Heise CE, Albert R, Cottens S, Hof R, et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J Biol Chem. 2002;277: 21453-7.
-
(2002)
J Biol Chem
, vol.277
, pp. 21453-21457
-
-
Brinkmann, V.1
Davis, M.D.2
Heise, C.E.3
Albert, R.4
Cottens, S.5
Hof, R.6
-
23
-
-
0347481389
-
Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases
-
Billich A, Bornancin F, Dévay P, Mechtcheriakova D, Urtz N, Baumruker T. Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases. J Biol Chem. 2003;278: 47408-15.
-
(2003)
J Biol Chem
, vol.278
, pp. 47408-47415
-
-
Billich, A.1
Bornancin, F.2
Dévay, P.3
Mechtcheriakova, D.4
Urtz, N.5
Baumruker, T.6
-
24
-
-
80053112315
-
Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia
-
Pfeilschifter W, Czech-Zechmeister B, Sujak M, Mirceska A, Koch A, Rami A, et al. Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia. Biochem Biophys Res Commun. 2011;413: 212-7.
-
(2011)
Biochem Biophys Res Commun
, vol.413
, pp. 212-217
-
-
Pfeilschifter, W.1
Czech-Zechmeister, B.2
Sujak, M.3
Mirceska, A.4
Koch, A.5
Rami, A.6
-
25
-
-
3042743990
-
FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function
-
Brinkmann V, Cyster JG, Hla T. FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. Am J Transplant. 2004;4: 1019-25.
-
(2004)
Am J Transplant
, vol.4
, pp. 1019-1025
-
-
Brinkmann, V.1
Cyster, J.G.2
Hla, T.3
-
26
-
-
33645283403
-
FTY720, sphingosine 1-phosphate receptor modulator, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration
-
Kataoka H, Sugahara K, Shimano K, Teshima K, Koyama M, Fukunari A, et al. FTY720, sphingosine 1-phosphate receptor modulator, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. Cell Mol Immunol. 2005;2: 439-48.
-
(2005)
Cell Mol Immunol
, vol.2
, pp. 439-448
-
-
Kataoka, H.1
Sugahara, K.2
Shimano, K.3
Teshima, K.4
Koyama, M.5
Fukunari, A.6
-
27
-
-
77950516464
-
Protective effects of early CD4(+) T cell reduction in hepatic ischemia/reperfusion injury
-
Martin M, Mory C, Prescher A, Wittekind C, Fiedler M, Uhlmann D. Protective effects of early CD4(+) T cell reduction in hepatic ischemia/reperfusion injury. J Gastrointest Surg. 2010;14: 511-9.
-
(2010)
J Gastrointest Surg
, vol.14
, pp. 511-519
-
-
Martin, M.1
Mory, C.2
Prescher, A.3
Wittekind, C.4
Fiedler, M.5
Uhlmann, D.6
-
29
-
-
35448947910
-
T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation
-
Hurn PD, Subramanian S, Parker SM, Afentoulis ME, Kaler LJ, Vandenbark AA, et al. T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation. J Cereb Blood Flow Metab. 2007;27: 1798-805.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1798-1805
-
-
Hurn, P.D.1
Subramanian, S.2
Parker, S.M.3
Afentoulis, M.E.4
Kaler, L.J.5
Vandenbark, A.A.6
-
30
-
-
70349327371
-
The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia
-
Czech B, Pfeilschifter W, Mazaheri-Omrani N, Strobel MA, Kahles T, Neumann-Haefelin T, et al. The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. Biochem Biophys Res Commun. 2009;389: 251-6.
-
(2009)
Biochem Biophys Res Commun
, vol.389
, pp. 251-256
-
-
Czech, B.1
Pfeilschifter, W.2
Mazaheri-Omrani, N.3
Strobel, M.A.4
Kahles, T.5
Neumann-Haefelin, T.6
-
31
-
-
68349160698
-
Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury
-
Shichita T, Sugiyama Y, Ooboshi H, Sugimori H, Nakagawa R, Takada I, et al. Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat Med. 2009;15: 946-50.
-
(2009)
Nat Med.
, vol.15
, pp. 946-950
-
-
Shichita, T.1
Sugiyama, Y.2
Ooboshi, H.3
Sugimori, H.4
Nakagawa, R.5
Takada, I.6
-
32
-
-
79551495392
-
Fingolimod provides long-term protection in rodent models of cerebral ischemia
-
Wei Y, Yemisci M, Kim HH, Yung LM, Shin HK, Hwang SK, et al. Fingolimod provides long-term protection in rodent models of cerebral ischemia. Ann Neurol. 2011;69: 119-29.
-
(2011)
Ann Neurol
, vol.69
, pp. 119-129
-
-
Wei, Y.1
Yemisci, M.2
Kim, H.H.3
Yung, L.M.4
Shin, H.K.5
Hwang, S.K.6
-
33
-
-
53049085954
-
Central nervous system-directed effects of FTY720 (fingolimod)
-
Miron VE, Schubart A, Antel JP. Central nervous system-directed effects of FTY720 (fingolimod). J Neurol Sci. 2008;274: 13-7.
-
(2008)
J Neurol Sci
, vol.274
, pp. 13-17
-
-
Miron, V.E.1
Schubart, A.2
Antel, J.P.3
-
34
-
-
83355169565
-
Brief history of behavioral assessment following experimental traumatic brain injury in juveniles
-
Hartman REA. Brief history of behavioral assessment following experimental traumatic brain injury in juveniles. Transl Stroke Res. 2011;2: 433-7.
-
(2011)
Transl Stroke Res
, vol.2
, pp. 433-437
-
-
Hartman, R.E.A.1
-
35
-
-
0034653872
-
Quantitative measurement of motor and somatosensory impairments after mild (30 min) and severe (2 h) transient middle cerebral artery occlusion in rats
-
Zhang L, Chen J, Li Y, Zhang ZG, Chopp M. Quantitative measurement of motor and somatosensory impairments after mild (30 min) and severe (2 h) transient middle cerebral artery occlusion in rats. J Neurol Sci. 2000;174: 141-6.
-
(2000)
J Neurol Sci
, vol.174
, pp. 141-146
-
-
Zhang, L.1
Chen, J.2
Li, Y.3
Zhang, Z.G.4
Chopp, M.5
-
36
-
-
79952538493
-
Long-term behavioral assessment of function in an experimental model for ischemic stroke
-
Encarnacion A, Horie N, Keren-Gill H, Bliss TM, Steinberg GK, Shamloo M. Long-term behavioral assessment of function in an experimental model for ischemic stroke. J Neurosci Methods. 2011;196: 247-57.
-
(2011)
J Neurosci Methods.
, vol.196
, pp. 247-257
-
-
Encarnacion, A.1
Horie, N.2
Keren-Gill, H.3
Bliss, T.M.4
Steinberg, G.K.5
Shamloo, M.6
-
37
-
-
84862788915
-
Transient focal cerebral ischemia induces long-term cerebral vasculature dysfunction in a rodent experimental stroke model
-
Winters A, Taylor JC, Ren M, Ma R, Liu R, Yang SH. Transient focal cerebral ischemia induces long-term cerebral vasculature dysfunction in a rodent experimental stroke model. Transl Stroke Res. 2012;3: 279-85.
-
(2012)
Transl Stroke Res.
, vol.3
, pp. 279-285
-
-
Winters, A.1
Taylor, J.C.2
Ren, M.3
Ma, R.4
Liu, R.5
Yang, S.H.6
|