Preliminary evidence that obese patients with obstructive sleep apnea/hypopnea syndrome are refractory to the acute beneficial metabolic effects of a very low calorie diet

Acta Diabetologica

Volumn 50, Issue 4, 2013, Pages 639-643

  Giordani, Ilaria ^a,b   Malandrucco, Ilaria ^a,b   Picconi, Fabiana ^a,b   Longo, Susanna ^a,b   Di Flaviani, Alessandra ^a,b   Chioma, Laura ^a,b   Moscatelli, Barbara ^b   Donno, Silvia ^b   Frontoni, Simona ^a,b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAN GIOVANNI CALIBITA FATEBENEFRATELLI HOSPITAL   (Italy)

Author keywords

Diet therapy; Insulin resistance, insulin secretion; Obesity metabolism; Obstructive sleep apnea; Type 2 diabetes

Indexed keywords

HEMOGLOBIN A1C;

ADULT; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY MASS; BODY SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; GLUCOSE REGULATION; HEART RATE; HUMAN; INSULIN SENSITIVITY; LOW CALORY DIET; MALE; METABOLIC PARAMETERS; MORBID OBESITY; NON INSULIN DEPENDENT DIABETES MELLITUS; OXYGEN DESATURATION INDEX; PRIORITY JOURNAL; REGULATORY MECHANISM; SLEEP DISORDERED BREATHING; SYSTOLIC BLOOD PRESSURE; THERAPY EFFECT; TREATMENT RESPONSE; VERY LOW CALORY DIET; WAIST CIRCUMFERENCE; WEIGHT REDUCTION;

CALORIC RESTRICTION; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; MALE; MIDDLE AGED; OBESITY; SLEEP APNEA, OBSTRUCTIVE;

EID: 84884903515     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-013-0487-5     Document Type: Article

References (34)

1. Rusu A, Todea D, Rosca L, Nita C, Bala C (2012) The development of a sleep apnea screening program in Romanian type 2 diabetic patients: a pilot study. Acta Diabetol 49(2):105-109
2. Foster GD, Sanders MH, Millman R et al (2009) Obstructive sleep apnea among obese patients with type 2 diabetes. Diabetes Care 32:1017-1019
3. Laaban JP, Daenen S, Léger D et al (2009) Prevalence and predictive factors of sleep apnoea syndrome in type 2 diabetic patients. Diabetes Metab 35:372-377
4. Resnick HE, Redline S, Shahar E et al (2003) Diabetes and sleep disturbances: findings from the Sleep Heart Health Study. Diabetes Care 26:702-709 (Pubitemid 36929331)
5. Lindberg E, Theorell-Haglöw J, Svensson M, Gislason T, Berne C, Janson C (2012) Sleep apnea and glucose metabolism: a long-term follow-up in a community-based sample. Chest 142(4):935-942
6. Oda E (2012) Metabolic syndrome: its history, mechanisms, and limitations. Acta Diabetol 49(2):89-95
7. Wright J, Johns R, Watt I, Melville A, Sheldon T (1997) Health effects of obstructive sleep apnoea and the effectiveness of continuous positive airways pressure: a systematic review of the research evidence. Br Med J 314:851-860 (Pubitemid 27182017)
8. Young T, Finn L, Peppard PE et al (2008) Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort. Sleep 31:1071-1078
9. Hecht L, Moehler R, Meyer G (2011) Effect of CPAP-respiration on markers of glucose metabolism in patients with obstructive sleep apnoea syndrome: a systematic review and meta-analysis. Ger Med Sci 9:1-13
10. O'Donnell CP (2007) Metabolic consequences of intermittent hypoxia. Adv Exp Med Biol 618:41-49
11. Ip MSM, Lam B, Ng MM, Lam WK, Tsang KWT, Lam KSL (2002) Obstructive sleep apnea is independently associated with insulin resistance. Am J Respir Crit Care Med 165:670-676 (Pubitemid 34194755)
12. Punjabi NM, Sorkin JD, Katzel LI, Goldberg AP, Schwartz AR, Smith PL (2002) Sleep-disordered breathing and insulin resistance in middle-aged and overweight men. Am J Respir Crit Care Med 165:677-682 (Pubitemid 34194756)
13. Meslier N, Gagnadoux F, Giraud P et al (2003) Impaired glucose-insulin metabolism in males with obstructive sleep apnoea syndrome. Eur Respir J 22:156-160 (Pubitemid 36896486)
14. Punjabi NM, Shahar E, Redline S, Gottlieb DJ, Givelber R, Resnick HE (2004) Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study. Am J Epidemiol 160:521-530 (Pubitemid 39215628)
15. Tiihonen M, Partinen M, Narvanen S (1993) The severity of obstructive sleep apnoea is associated with insulin resistance. J Sleep Res 2:56-61 (Pubitemid 23137512)
16. Newman AB, Foster G, Givelber R, Nieto FJ, Redline S, Young T (2005) Progression and regression of sleep-disordered breathing with changes in weight: the Sleep Heart Health Study. Arch Intern Med 165:2408-2413 (Pubitemid 41640854)
17. Foster GD, Borradaile KE, Sanders MH, For the Sleep AHEAD Research Group of the Look AHEAD Research Group et al (2009) The sleep ahead study a randomized study on the effect of weight loss on obstructive sleep apnea among obese patients with type 2 diabetes. Arch Intern Med 169(17):1619-1626
18. Tuomilehto HP, Seppa JM, Partinen MM et al (2009) Lifestyle intervention with weight reduction: first-line treatment in mild obstructive sleep apnea. Am J Respir Crit Care Med 179:320-327
19. Johansson K, Neovius M, Lagerros YT et al (2009) Effect of a very low energy diet on moderate and severe obstructive sleep apnoea in obese men: a randomized controlled trial. BMJ 339:b4609
20. Dixon J, Schachter L, O'Brien P, Jones K et al (2012) Surgical versus conventional therapy for weight loss treatment of obstructive sleep apnea. JAMA 308(11):1142-1149
21. Lim EL, Hollingsworth KG, Aribisala BS, Chen MJ, Mathers JC, Taylor R (2011) Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. Diabetologia 54:2506-2514
22. Malandrucco I, Pasqualetti P, Giordani I et al (2012) Very-low-calorie diet: a quick therapeutic tool to improve β cell function in morbidly obese patients with type 2 diabetes. Am J Clin Nutr 95:609-613
23. American Diabetes Association (2010) Diagnosis and classification of diabetes mellitus. Diabetes Care 33(suppl 1):S62-S69
24. Netzer N, Eliasson AH, Netzer C, Kristo DA (2001) Overnight pulse oximetry for sleep-disordered breathing in adults. Chest 120:625-633 (Pubitemid 32881286)
25. DeFronzo RA, Tobin JD, Andres R (1979) Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237(suppl 3):E214-E223
26. Mari A, Ahre′n B, Pacini G (2005) Assessment of insulin secretion in relation to insulin resistance. Curr Opin Clin Nutr Metab Care 8:529-533 (Pubitemid 41192329)
27. Pontiroli AE, Merlotti C, Veronelli A, Lombardi F (2013). Effect of weight loss on sympatho-vagal balance in subjects with grade-3 obesity: restrictive surgery versus hypocaloric diet. Acta Diabetol. doi: 10.1007/s00592-013-0454-1
28. Frontoni S, Bracaglia D, Gigli F (2005) Relationship between autonomic dysfunction, insulin resistance and hypertension, in diabetes. Nutr Metab Cardiovasc Dis 15(6):441-449 (Pubitemid 43986479)
29. Ota H, Tamaki S, Itaya-Hironaka A et al (2012) Attenuation of glucose-induced insulin secretion by intermittent hypoxia via down-regulation of CD38. Life Sci 90(5-6):206-211
30. Antonelli A, Ferrannini E (2004) CD38 autoimmunity: recent advances and relevance to human diabetes. J Endocrinol Invest 27(7):243-252
31. Yokoe T, Alonso LC, Romano LC et al (2008) Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in mice. J Physiol 586(3):899-911 (Pubitemid 351194126)
32. Xu J, Long YS, Gozal D, Epstein PN (2009) Beta-cell death and proliferation after intermittent hypoxia: role of oxidative stress. Free Radic Biol Med 46(6):783-790
33. Cnop M, Hughes SJ, Igoillo-Esteve M et al (2009) The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation. Diabetologia 53(2):321-330
34. Perl S, Kushner JA, Buchholz BA et al (2010) Significant human beta-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating. Am J Physiol 95(10):E234-E239