Polyethylene glycated leukemia inhibitory factor antagonist inhibits human blastocyst implantation and triggers apoptosis by down-regulating embryonic AKT

Fertility and Sterility

Volumn 100, Issue 4, 2013, Pages

  Lalitkumar, Sujata ^a   Boggavarapu, Nageswara R ^a   Menezes, Judith ^b   Dimitriadis, Evdokia ^c,d   Zhang, Jian Guo ^e   Nicola, Nicos A ^e   Gemzell Danielsson, Kristina ^a   Lalitkumar, Luther P G ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Fertilitetscentrum   (Sweden)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d MONASH UNIVERSITY   (Australia)

^e WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

AKT; apoptosis; embryo attachment; LIF; PEGLA

Indexed keywords

CASPASE 3; CYTOKINE RECEPTOR ANTAGONIST; LEUKEMIA INHIBITORY FACTOR; LUTEINIZING HORMONE; MESSENGER RNA; POLYETHYLENE GLYCATED LEUKEMIA INHIBITORY FACTOR ANTAGONIST; PROTEIN KINASE B; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DONOR; DOWN REGULATION; DRUG EFFECT; EMBRYO; ENDOMETRIUM; ENDOMETRIUM BIOPSY; ENZYME ACTIVATION; ENZYME REGULATION; EPITHELIUM CELL; FEMALE; FERTILIZATION IN VITRO; FROZEN SECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IN VITRO STUDY; NIDATION; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; THAWING; UNIVERSITY HOSPITAL;

AKT; APOPTOSIS; EMBRYO ATTACHMENT; LIF; PEGLA;

APOPTOSIS; BIOPSY; BLASTOCYST; CASPASE 3; DOWN-REGULATION; EMBRYO CULTURE TECHNIQUES; EMBRYO IMPLANTATION; ENDOMETRIUM; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LEUKEMIA INHIBITORY FACTOR; PHOSPHORYLATION; POLYETHYLENE GLYCOLS; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84884901883     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.06.023     Document Type: Article

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