-
1
-
-
33747878559
-
A recombinant human enzyme for enhanced interstitial transport of therapeutics
-
L. H. Bookbinder A. Hofer M. F. Haller et al. A recombinant human enzyme for enhanced interstitial transport of therapeutics J. Controlled Release 2006 114 230 241
-
(2006)
J. Controlled Release
, vol.114
, pp. 230-241
-
-
Bookbinder, L.H.1
Hofer, A.2
Haller, M.F.3
-
2
-
-
23144448579
-
Hyaluronidase induces a transcapillary pressure gradient and improves the distribution and uptake of liposomal doxorubicin (Caelyx) in human osteosarcoma xenografts
-
L. Eikenes M. Tari I. Tufto O. S. Bruland C. de Lange Davies Hyaluronidase induces a transcapillary pressure gradient and improves the distribution and uptake of liposomal doxorubicin (Caelyx) in human osteosarcoma xenografts Br. J. Cancer 2005 93 81 88
-
(2005)
Br. J. Cancer
, vol.93
, pp. 81-88
-
-
Eikenes, L.1
Tari, M.2
Tufto, I.3
Bruland, O.S.4
De Lange Davies, C.5
-
3
-
-
0029918307
-
Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma implanted in nude mice
-
I. Muckenschnabel G. Bernhardt T. Spruss A. Buschauer Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma implanted in nude mice Cancer Chemother. Pharmacol. 1996 38 88 94
-
(1996)
Cancer Chemother. Pharmacol.
, vol.38
, pp. 88-94
-
-
Muckenschnabel, I.1
Bernhardt, G.2
Spruss, T.3
Buschauer, A.4
-
4
-
-
73349134974
-
Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities
-
B. P. Toole Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities Clin. Cancer Res. 2009 15 7462 7468
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 7462-7468
-
-
Toole, B.P.1
-
5
-
-
84871157346
-
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
-
M. A. Jacobetz D. S. Chan A. Neesse et al. Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer Gut 2013 62 112 120
-
(2013)
Gut
, vol.62
, pp. 112-120
-
-
Jacobetz, M.A.1
Chan, D.S.2
Neesse, A.3
-
6
-
-
0017373031
-
Interstitial fluid pressure in rats measured with a modified wick technique
-
H. O. Fadnes R. K. Reed K. Aukland Interstitial fluid pressure in rats measured with a modified wick technique Microvasc. Res. 1977 14 27 36
-
(1977)
Microvasc. Res.
, vol.14
, pp. 27-36
-
-
Fadnes, H.O.1
Reed, R.K.2
Aukland, K.3
-
8
-
-
84872611820
-
Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer
-
P. P. Provenzano S. R. Hingorani Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer Br. J. Cancer 2013 108 1 8
-
(2013)
Br. J. Cancer
, vol.108
, pp. 1-8
-
-
Provenzano, P.P.1
Hingorani, S.R.2
-
9
-
-
0032508626
-
Hyaluronidase and its substrate hyaluronan: Biochemistry, biological activities and therapeutic uses
-
E. J. Menzel C. Farr Hyaluronidase and its substrate hyaluronan: biochemistry, biological activities and therapeutic uses Cancer Lett. 1998 131 3 11
-
(1998)
Cancer Lett.
, vol.131
, pp. 3-11
-
-
Menzel, E.J.1
Farr, C.2
-
10
-
-
34249315132
-
Matrix assisted laser desorption ionization-time of flight mass spectrometry analysis of hyaluronan oligosaccharides
-
S. Sakai K. Hirano H. Toyoda R. J. Linhardt T. Toida Matrix assisted laser desorption ionization-time of flight mass spectrometry analysis of hyaluronan oligosaccharides Anal. Chim. Acta 2007 593 207 213
-
(2007)
Anal. Chim. Acta
, vol.593
, pp. 207-213
-
-
Sakai, S.1
Hirano, K.2
Toyoda, H.3
Linhardt, R.J.4
Toida, T.5
-
11
-
-
34948838979
-
Degradation of high-molar-mass hyaluronan and characterization of fragments
-
L. Soltes G. Kogan M. Stankovska et al. Degradation of high-molar-mass hyaluronan and characterization of fragments Biomacromolecules 2007 8 2697 2705
-
(2007)
Biomacromolecules
, vol.8
, pp. 2697-2705
-
-
Soltes, L.1
Kogan, G.2
Stankovska, M.3
-
12
-
-
0026546590
-
Identification of the reaction products of the purified hyaluronidase from stonefish (Synanceja horrida) venom
-
K. Sugahara S. Yamada M. Sugiura et al. Identification of the reaction products of the purified hyaluronidase from stonefish (Synanceja horrida) venom Biochem. J. 1992 283 Pt 1 99 104
-
(1992)
Biochem. J.
, vol.283
, Issue.PART 1
, pp. 99-104
-
-
Sugahara, K.1
Yamada, S.2
Sugiura, M.3
-
13
-
-
72449167901
-
Hyaluronidase: A review of approved formulations, indications and off-label use in chronic pain management
-
A. L. Dunn J. E. Heavner G. Racz M. Day Hyaluronidase: a review of approved formulations, indications and off-label use in chronic pain management Expert Opin. Biol. Ther. 2010 10 127 131
-
(2010)
Expert Opin. Biol. Ther.
, vol.10
, pp. 127-131
-
-
Dunn, A.L.1
Heavner, J.E.2
Racz, G.3
Day, M.4
-
14
-
-
84884845746
-
-
Hyaluronidase Monograph (Amphadase, Hydase, Vitrase, Hylenex) Final, in: National PBM Drug Monograph, VHA Pharmacy Benefits Management Service and the Medical Advisory Panel, Washington, DC
-
Hyaluronidase Monograph (Amphadase, Hydase, Vitrase, Hylenex) Final, in: National PBM Drug Monograph, http://www.pbm.va.gov/Clinical%20Guidance/ Drug%20Monographs/Hyaluronidase%20Monograph%20(Amphadase,%20Hydase,%20Vitrase, %20Hylenex)%20Final.doc:, VHA Pharmacy Benefits Management Service and the Medical Advisory Panel, Washington, DC, 2008
-
(2008)
-
-
-
16
-
-
84884838991
-
-
ClinicalTrials.gov.in, U.S. National Institutes of Health
-
ClinicalTrials.gov.in, http://www.clinicaltrials.gov/ct2/results?term= PEGPH20&Search=Search:, U.S. National Institutes of Health
-
-
-
-
17
-
-
0032508620
-
Hyaluronidase reduces the interstitial fluid pressure in solid tumours in a non-linear concentration-dependent manner
-
C. Brekken C. de Lange Davies Hyaluronidase reduces the interstitial fluid pressure in solid tumours in a non-linear concentration-dependent manner Cancer Lett. 1998 131 65 70
-
(1998)
Cancer Lett.
, vol.131
, pp. 65-70
-
-
Brekken, C.1
De Lange Davies, C.2
-
18
-
-
84858602107
-
Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma
-
P. P. Provenzano C. Cuevas A. E. Chang V. K. Goel D. D. Von Hoff S. R. Hingorani Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma Cancer cell 2012 21 418 429
-
(2012)
Cancer Cell
, vol.21
, pp. 418-429
-
-
Provenzano, P.P.1
Cuevas, C.2
Chang, A.E.3
Goel, V.K.4
Von Hoff, D.D.5
Hingorani, S.R.6
-
20
-
-
77955403005
-
Hyaluronidase expression by an oncolytic adenovirus enhances its intratumoral spread and suppresses tumor growth
-
S. Guedan J. J. Rojas A. Gros E. Mercade M. Cascallo R. Alemany Hyaluronidase expression by an oncolytic adenovirus enhances its intratumoral spread and suppresses tumor growth Mol. Ther. 2010 18 1275 1283
-
(2010)
Mol. Ther.
, vol.18
, pp. 1275-1283
-
-
Guedan, S.1
Rojas, J.J.2
Gros, A.3
Mercade, E.4
Cascallo, M.5
Alemany, R.6
-
21
-
-
52449091656
-
Intratumoral coadministration of hyaluronidase enzyme and oncolytic adenoviruses enhances virus potency in metastatic tumor models
-
S. Ganesh M. Gonzalez-Edick D. Gibbons M. Van Roey K. Jooss Intratumoral coadministration of hyaluronidase enzyme and oncolytic adenoviruses enhances virus potency in metastatic tumor models Clin. Cancer Res. 2008 14 3933 3941
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3933-3941
-
-
Ganesh, S.1
Gonzalez-Edick, M.2
Gibbons, D.3
Van Roey, M.4
Jooss, K.5
-
22
-
-
84855916276
-
Macrophage metalloelastase (MME) as adjuvant for intra-tumoral injection of oncolytic adenovirus and its influence on metastases development
-
S. Lavilla-Alonso M. M. Bauer U. Abo-Ramadan et al. Macrophage metalloelastase (MME) as adjuvant for intra-tumoral injection of oncolytic adenovirus and its influence on metastases development Cancer Gene Ther. 2012 19 126 134
-
(2012)
Cancer Gene Ther.
, vol.19
, pp. 126-134
-
-
Lavilla-Alonso, S.1
Bauer, M.M.2
Abo-Ramadan, U.3
-
23
-
-
0033635842
-
Hyaluronidase-induced periodic modulation of the interstitial fluid pressure increases selective antibody uptake in human osteosarcoma xenografts
-
C. Brekken M. H. Hjelstuen O. S. Bruland C. de Lange Davies Hyaluronidase-induced periodic modulation of the interstitial fluid pressure increases selective antibody uptake in human osteosarcoma xenografts Anticancer Res. 2000 20 3513 3519
-
(2000)
Anticancer Res.
, vol.20
, pp. 3513-3519
-
-
Brekken, C.1
Hjelstuen, M.H.2
Bruland, O.S.3
De Lange Davies, C.4
-
24
-
-
84865980140
-
Hyaluronic acid-functionalized mesoporous silica nanoparticles for efficient photodynamic therapy of cancer cells
-
M. Gary-Bobo D. Brevet N. Benkirane-Jessel et al. Hyaluronic acid-functionalized mesoporous silica nanoparticles for efficient photodynamic therapy of cancer cells Photodiagn. Photodyn. Ther. 2012 9 256 260
-
(2012)
Photodiagn. Photodyn. Ther.
, vol.9
, pp. 256-260
-
-
Gary-Bobo, M.1
Brevet, D.2
Benkirane-Jessel, N.3
-
25
-
-
84555202674
-
Nanoparticles in targeted cancer therapy: Mesoporous silica nanoparticles entering preclinical development stage
-
J. M. Rosenholm V. Mamaeva C. Sahlgren M. Linden Nanoparticles in targeted cancer therapy: mesoporous silica nanoparticles entering preclinical development stage Nanomedicine 2012 7 111 120
-
(2012)
Nanomedicine
, vol.7
, pp. 111-120
-
-
Rosenholm, J.M.1
Mamaeva, V.2
Sahlgren, C.3
Linden, M.4
-
26
-
-
34547893864
-
Recombinant human hyaluronidase (rHuPH20): An enabling platform for subcutaneous drug and fluid administration
-
G. I. Frost Recombinant human hyaluronidase (rHuPH20): an enabling platform for subcutaneous drug and fluid administration Expert Opin. Drug Delivery 2007 4 427 440
-
(2007)
Expert Opin. Drug Delivery
, vol.4
, pp. 427-440
-
-
Frost, G.I.1
-
27
-
-
20444406055
-
Controlled growth of monodisperse silica spheres in the micron size range
-
W. Stöber A. Fink E. Bohn Controlled growth of monodisperse silica spheres in the micron size range J. Colloid Interface Sci. 1968 26 62 69
-
(1968)
J. Colloid Interface Sci.
, vol.26
, pp. 62-69
-
-
Stöber, W.1
Fink, A.2
Bohn, E.3
-
28
-
-
79960027556
-
Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma
-
M. Benezra O. Penate-Medina P. B. Zanzonico et al. Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma J. Clin. Invest. 2011 121 2768 2780
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2768-2780
-
-
Benezra, M.1
Penate-Medina, O.2
Zanzonico, P.B.3
-
29
-
-
80051944950
-
Systematic Tuning the Hydrodynamic Diameter of Uniformed Fluorescent Silica Nanoparticles
-
G. Durgun K. Ocakoglu S. Ozcelik Systematic Tuning the Hydrodynamic Diameter of Uniformed Fluorescent Silica Nanoparticles J. Phys. Chem. C 2011 115 16322 16332
-
(2011)
J. Phys. Chem. C
, vol.115
, pp. 16322-16332
-
-
Durgun, G.1
Ocakoglu, K.2
Ozcelik, S.3
-
30
-
-
0030848621
-
Fuzzy Nanoassemblies: Toward Layered Polymeric Multicomposites
-
G. Decher Fuzzy Nanoassemblies: Toward Layered Polymeric Multicomposites Science 1997 277 1232 1237
-
(1997)
Science
, vol.277
, pp. 1232-1237
-
-
Decher, G.1
-
31
-
-
0033528615
-
Investigation of Electrostatic Interactions in Polyelectrolyte Multilayer Films: Binding of Anionic Fluorescent Probes to Layers Assembled onto Colloids
-
F. Caruso H. Lichtenfeld E. Donath H. Möhwald Investigation of Electrostatic Interactions in Polyelectrolyte Multilayer Films: Binding of Anionic Fluorescent Probes to Layers Assembled onto Colloids Macromolecules 1999 32 2317 2328
-
(1999)
Macromolecules
, vol.32
, pp. 2317-2328
-
-
Caruso, F.1
Lichtenfeld, H.2
Donath, E.3
Möhwald, H.4
-
32
-
-
77955566033
-
Layer-by-layer self-assembled osmium polymer-mediated laccase oxygen cathodes for biofuel cells: The role of hydrogen peroxide
-
P. Scodeller R. Carballo R. Szamocki L. Levin F. Forchiassin E. J. Calvo Layer-by-layer self-assembled osmium polymer-mediated laccase oxygen cathodes for biofuel cells: the role of hydrogen peroxide J. Am. Chem. Soc. 2010 132 11132 11140
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 11132-11140
-
-
Scodeller, P.1
Carballo, R.2
Szamocki, R.3
Levin, L.4
Forchiassin, F.5
Calvo, E.J.6
-
33
-
-
52449104863
-
Wired-enzyme core-shell Au nanoparticle biosensor
-
P. Scodeller V. Flexer R. Szamocki et al. Wired-enzyme core-shell Au nanoparticle biosensor J. Am. Chem. Soc. 2008 130 12690 12697
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 12690-12697
-
-
Scodeller, P.1
Flexer, V.2
Szamocki, R.3
-
34
-
-
30744458092
-
Structure and thickness dependence of molecular wiring in nanostructured enzyme multilayers
-
V. Flexer E. S. Forzani E. J. Calvo S. J. Luduena L. I. Pietrasanta Structure and thickness dependence of "molecular wiring" in nanostructured enzyme multilayers Anal. Chem. 2006 78 399 407
-
(2006)
Anal. Chem.
, vol.78
, pp. 399-407
-
-
Flexer, V.1
Forzani, E.S.2
Calvo, E.J.3
Luduena, S.J.4
Pietrasanta, L.I.5
-
35
-
-
0036180779
-
Importance of glycosylation and disulfide bonds in hyaluronidase activity of macaque sperm surface PH-20
-
M. W. Li A. I. Yudin K. R. Robertson G. N. Cherr J. W. Overstreet Importance of glycosylation and disulfide bonds in hyaluronidase activity of macaque sperm surface PH-20 J. Androl. 2002 23 211 219
-
(2002)
J. Androl.
, vol.23
, pp. 211-219
-
-
Li, M.W.1
Yudin, A.I.2
Robertson, K.R.3
Cherr, G.N.4
Overstreet, J.W.5
-
36
-
-
4243682146
-
Enzyme Multilayers on Colloid Particles: Assembly, Stability, and Enzymatic Activity
-
F. Caruso C. Schüler Enzyme Multilayers on Colloid Particles: Assembly, Stability, and Enzymatic Activity Langmuir 2000 16 9595 9603
-
(2000)
Langmuir
, vol.16
, pp. 9595-9603
-
-
Caruso, F.1
Schüler, C.2
-
38
-
-
79955398620
-
Hyaluronidase behavior at the air/liquid and air/lipid interfaces and improved enzymatic activity by its immobilization in a biomembrane model
-
D. S. Monteiro T. M. Nobre M. E. Zaniquelli Hyaluronidase behavior at the air/liquid and air/lipid interfaces and improved enzymatic activity by its immobilization in a biomembrane model J. Phys. Chem. B 2011 115 4801 4809
-
(2011)
J. Phys. Chem. B
, vol.115
, pp. 4801-4809
-
-
Monteiro, D.S.1
Nobre, T.M.2
Zaniquelli, M.E.3
-
39
-
-
0022409599
-
Glycosaminoglycan production by murine melanoma variants in vivo and in vitro
-
E. A. Turley M. Tretiak Glycosaminoglycan production by murine melanoma variants in vivo and in vitro Cancer Res. 1985 45 5098 5105
-
(1985)
Cancer Res.
, vol.45
, pp. 5098-5105
-
-
Turley, E.A.1
Tretiak, M.2
-
40
-
-
78650134637
-
Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line
-
H. Meng M. Liong T. Xia et al. Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line ACS Nano 2010 4 4539 4550
-
(2010)
ACS Nano
, vol.4
, pp. 4539-4550
-
-
Meng, H.1
Liong, M.2
Xia, T.3
-
41
-
-
84856933120
-
Magnetically Triggered Multidrug Release by Hybrid Mesoporous Silica Nanoparticles
-
A. Baeza E. Guisasola E. Ruiz-Hernández M. Vallet-Regí Magnetically Triggered Multidrug Release by Hybrid Mesoporous Silica Nanoparticles Chem. Mater. 2012 24 517 524
-
(2012)
Chem. Mater.
, vol.24
, pp. 517-524
-
-
Baeza, A.1
Guisasola, E.2
Ruiz-Hernández, E.3
Vallet-Regí, M.4
-
42
-
-
84886593939
-
A phase Ib study of gemcitabine plus PEGPH20 (pegylated recombinant human hyaluronidase) in patients with stage IV previously untreated pancreatic cancer. In: 2013 American Society of Clinical Oncology Annual Meeting, Chicago, IL
-
S. R. Hingorani W. P. Harris J. T. Beck et al. A phase Ib study of gemcitabine plus PEGPH20 (pegylated recombinant human hyaluronidase) in patients with stage IV previously untreated pancreatic cancer. In: 2013 American Society of Clinical Oncology Annual Meeting, Chicago, IL J. Clin. Oncol. 2013 31 suppl. 4010
-
(2013)
J. Clin. Oncol.
, vol.31
, Issue.SUPPL. 4010
-
-
Hingorani, S.R.1
Harris, W.P.2
Beck, J.T.3
-
43
-
-
84884885298
-
-
Sigma-Aldrich. Enzymatic Assay of Hyaluronidase
-
Sigma-Aldrich. Enzymatic Assay of Hyaluronidase, http://www.sigmaaldrich. com/technical-documents/protocols/biology/enzymatic-assay-of-hyaluronidase.html
-
-
-
|