-
1
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, et al. (2005) Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 175: 2851-2858.
-
(2005)
J Immunol
, vol.175
, pp. 2851-2858
-
-
Yoneyama, M.1
Kikuchi, M.2
Matsumoto, K.3
Imaizumi, T.4
Miyagishi, M.5
-
2
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, et al. (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441: 101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
-
3
-
-
37349052379
-
Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity
-
Loo YM, Fornek J, Crochet N, Bajwa G, Perwitasari O, et al. (2008) Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J Virol 82: 335-345.
-
(2008)
J Virol
, vol.82
, pp. 335-345
-
-
Loo, Y.M.1
Fornek, J.2
Crochet, N.3
Bajwa, G.4
Perwitasari, O.5
-
4
-
-
79959344720
-
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells
-
Zhang Z, Kim T, Bao M, Facchinetti V, Jung SY, et al. (2011) DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells. Immunity 34: 866-878.
-
(2011)
Immunity
, vol.34
, pp. 866-878
-
-
Zhang, Z.1
Kim, T.2
Bao, M.3
Facchinetti, V.4
Jung, S.Y.5
-
6
-
-
30444450839
-
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
-
Stetson DB, Medzhitov R, (2006) Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 24: 93-103.
-
(2006)
Immunity
, vol.24
, pp. 93-103
-
-
Stetson, D.B.1
Medzhitov, R.2
-
7
-
-
77955415407
-
Activation of host pattern recognition receptors by viruses
-
Brennan K, Bowie AG, (2010) Activation of host pattern recognition receptors by viruses. Curr Opin Microbiol 13: 503-507.
-
(2010)
Curr Opin Microbiol
, vol.13
, pp. 503-507
-
-
Brennan, K.1
Bowie, A.G.2
-
9
-
-
79951671973
-
New developments in the induction and antiviral effectors of type I interferon
-
Liu SY, Sanchez DJ, Cheng G, (2011) New developments in the induction and antiviral effectors of type I interferon. Curr Opin Immunol 23: 57-64.
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 57-64
-
-
Liu, S.Y.1
Sanchez, D.J.2
Cheng, G.3
-
10
-
-
79955542915
-
A diverse range of gene products are effectors of the type I interferon antiviral response
-
Schoggins JW, Wilson SJ, Panis M, Murphy MY, Jones CT, et al. (2011) A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472: 481-485.
-
(2011)
Nature
, vol.472
, pp. 481-485
-
-
Schoggins, J.W.1
Wilson, S.J.2
Panis, M.3
Murphy, M.Y.4
Jones, C.T.5
-
11
-
-
84856226112
-
Immunomodulatory functions of type I interferons
-
Gonzalez-Navajas JM, Lee J, David M, Raz E, (2012) Immunomodulatory functions of type I interferons. Nat Rev Immunol 12: 125-135.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 125-135
-
-
Gonzalez-Navajas, J.M.1
Lee, J.2
David, M.3
Raz, E.4
-
12
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T, Akira S, (2011) Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34: 637-650.
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
13
-
-
70350441863
-
Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands
-
Barbalat R, Lau L, Locksley RM, Barton GM, (2009) Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands. Nat Immunol 10: 1200-1207.
-
(2009)
Nat Immunol
, vol.10
, pp. 1200-1207
-
-
Barbalat, R.1
Lau, L.2
Locksley, R.M.3
Barton, G.M.4
-
14
-
-
59749092826
-
Respiratory syncytial virus activates innate immunity through Toll-like receptor 2
-
Murawski MR, Bowen GN, Cerny AM, Anderson LJ, Haynes LM, et al. (2009) Respiratory syncytial virus activates innate immunity through Toll-like receptor 2. J Virol 83: 1492-1500.
-
(2009)
J Virol
, vol.83
, pp. 1492-1500
-
-
Murawski, M.R.1
Bowen, G.N.2
Cerny, A.M.3
Anderson, L.J.4
Haynes, L.M.5
-
15
-
-
33646200348
-
Role for TLR2 in NK cell-mediated control of murine cytomegalovirus in vivo
-
Szomolanyi-Tsuda E, Liang X, Welsh RM, Kurt-Jones EA, Finberg RW, (2006) Role for TLR2 in NK cell-mediated control of murine cytomegalovirus in vivo. J Virol 80: 4286-4291.
-
(2006)
J Virol
, vol.80
, pp. 4286-4291
-
-
Szomolanyi-Tsuda, E.1
Liang, X.2
Welsh, R.M.3
Kurt-Jones, E.A.4
Finberg, R.W.5
-
16
-
-
26444549006
-
Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages via Toll-like receptor 2
-
Wang JP, Kurt-Jones EA, Shin OS, Manchak MD, Levin MJ, et al. (2005) Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages via Toll-like receptor 2. J Virol 79: 12658-12666.
-
(2005)
J Virol
, vol.79
, pp. 12658-12666
-
-
Wang, J.P.1
Kurt-Jones, E.A.2
Shin, O.S.3
Manchak, M.D.4
Levin, M.J.5
-
17
-
-
79956314385
-
Host defense pathways: role of redundancy and compensation in infectious disease phenotypes
-
Nish S, Medzhitov R, (2011) Host defense pathways: role of redundancy and compensation in infectious disease phenotypes. Immunity 34: 629-636.
-
(2011)
Immunity
, vol.34
, pp. 629-636
-
-
Nish, S.1
Medzhitov, R.2
-
18
-
-
3142676728
-
Developing animal models for polymicrobial diseases
-
Bakaletz LO, (2004) Developing animal models for polymicrobial diseases. Nat Rev Microbiol 2: 552-568.
-
(2004)
Nat Rev Microbiol
, vol.2
, pp. 552-568
-
-
Bakaletz, L.O.1
-
19
-
-
84862622032
-
Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses
-
Negishi H, Yanai H, Nakajima A, Koshiba R, Atarashi K, et al. (2012) Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. Nat Immunol 13: 659-666.
-
(2012)
Nat Immunol
, vol.13
, pp. 659-666
-
-
Negishi, H.1
Yanai, H.2
Nakajima, A.3
Koshiba, R.4
Atarashi, K.5
-
20
-
-
0037218547
-
Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components
-
Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, et al. (2003) Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components. J Immunol 170: 508-519.
-
(2003)
J Immunol
, vol.170
, pp. 508-519
-
-
Dobrovolskaia, M.A.1
Medvedev, A.E.2
Thomas, K.E.3
Cuesta, N.4
Toshchakov, V.5
-
21
-
-
79959447465
-
Structural biology of the Toll-like receptor family
-
Kang JY, Lee JO, (2011) Structural biology of the Toll-like receptor family. Annu Rev Biochem 80: 917-941.
-
(2011)
Annu Rev Biochem
, vol.80
, pp. 917-941
-
-
Kang, J.Y.1
Lee, J.O.2
-
22
-
-
33745945755
-
Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease
-
Medvedev AE, Sabroe I, Hasday JD, Vogel SN, (2006) Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease. J Endotoxin Res 12: 133-150.
-
(2006)
J Endotoxin Res
, vol.12
, pp. 133-150
-
-
Medvedev, A.E.1
Sabroe, I.2
Hasday, J.D.3
Vogel, S.N.4
-
23
-
-
70349650125
-
Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling
-
Piao W, Song C, Chen H, Diaz MA, Wahl LM, et al. (2009) Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling. J Leukoc Biol 86: 863-875.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 863-875
-
-
Piao, W.1
Song, C.2
Chen, H.3
Diaz, M.A.4
Wahl, L.M.5
-
24
-
-
0037114185
-
Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
-
Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, et al. (2002) Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J Immunol 169: 6668-6672.
-
(2002)
J Immunol
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
-
25
-
-
0032015647
-
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo
-
Wathelet MG, Lin CH, Parekh BS, Ronco LV, Howley PM, et al. (1998) Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell 1: 507-518.
-
(1998)
Mol Cell
, vol.1
, pp. 507-518
-
-
Wathelet, M.G.1
Lin, C.H.2
Parekh, B.S.3
Ronco, L.V.4
Howley, P.M.5
-
26
-
-
0034122095
-
Assembly of a functional beta interferon enhanceosome is dependent on ATF-2-c-jun heterodimer orientation
-
Falvo JV, Parekh BS, Lin CH, Fraenkel E, Maniatis T, (2000) Assembly of a functional beta interferon enhanceosome is dependent on ATF-2-c-jun heterodimer orientation. Mol Cell Biol 20: 4814-4825.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4814-4825
-
-
Falvo, J.V.1
Parekh, B.S.2
Lin, C.H.3
Fraenkel, E.4
Maniatis, T.5
-
27
-
-
34250823515
-
Gene-specific control of inflammation by TLR-induced chromatin modifications
-
Foster SL, Hargreaves DC, Medzhitov R, (2007) Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 447: 972-978.
-
(2007)
Nature
, vol.447
, pp. 972-978
-
-
Foster, S.L.1
Hargreaves, D.C.2
Medzhitov, R.3
-
28
-
-
78651101982
-
Facultative heterochromatin formation at the IL-1 beta promoter in LPS tolerance and sepsis
-
Yoza BK, McCall CE, (2011) Facultative heterochromatin formation at the IL-1 beta promoter in LPS tolerance and sepsis. Cytokine 53: 145-152.
-
(2011)
Cytokine
, vol.53
, pp. 145-152
-
-
Yoza, B.K.1
McCall, C.E.2
-
29
-
-
84862908693
-
The TLR4-TRIF pathway protects against H5N1 influenza virus infection
-
Shinya K, Ito M, Makino A, Tanaka M, Miyake K, et al. (2012) The TLR4-TRIF pathway protects against H5N1 influenza virus infection. J Virol 86: 19-24.
-
(2012)
J Virol
, vol.86
, pp. 19-24
-
-
Shinya, K.1
Ito, M.2
Makino, A.3
Tanaka, M.4
Miyake, K.5
-
30
-
-
20344384993
-
Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes
-
Stout RD, Suttles J, (2005) Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes. Immunol Rev 205: 60-71.
-
(2005)
Immunol Rev
, vol.205
, pp. 60-71
-
-
Stout, R.D.1
Suttles, J.2
-
31
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ, (2005) Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122: 669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
32
-
-
30544451546
-
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
-
Hacker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, et al. (2006) Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 439: 204-207.
-
(2006)
Nature
, vol.439
, pp. 204-207
-
-
Hacker, H.1
Redecke, V.2
Blagoev, B.3
Kratchmarova, I.4
Hsu, L.C.5
-
33
-
-
30544447047
-
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
-
Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, et al. (2006) Critical role of TRAF3 in the Toll-like receptor-dependent and-independent antiviral response. Nature 439: 208-211.
-
(2006)
Nature
, vol.439
, pp. 208-211
-
-
Oganesyan, G.1
Saha, S.K.2
Guo, B.3
He, J.Q.4
Shahangian, A.5
-
34
-
-
33745226259
-
Toll-like receptor adaptor molecules enhance DNA-raised adaptive immune responses against influenza and tumors through activation of innate immunity
-
Takeshita F, Tanaka T, Matsuda T, Tozuka M, Kobiyama K, et al. (2006) Toll-like receptor adaptor molecules enhance DNA-raised adaptive immune responses against influenza and tumors through activation of innate immunity. J Virol 80: 6218-6224.
-
(2006)
J Virol
, vol.80
, pp. 6218-6224
-
-
Takeshita, F.1
Tanaka, T.2
Matsuda, T.3
Tozuka, M.4
Kobiyama, K.5
-
35
-
-
0345505220
-
Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2
-
Compton T, Kurt-Jones EA, Boehme KW, Belko J, Latz E, et al. (2003) Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2. J Virol 77: 4588-4596.
-
(2003)
J Virol
, vol.77
, pp. 4588-4596
-
-
Compton, T.1
Kurt-Jones, E.A.2
Boehme, K.W.3
Belko, J.4
Latz, E.5
-
36
-
-
80052383971
-
Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice
-
Nakamura S, Davis KM, Weiser JN, (2011) Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice. J Clin Invest 121: 3657-3665.
-
(2011)
J Clin Invest
, vol.121
, pp. 3657-3665
-
-
Nakamura, S.1
Davis, K.M.2
Weiser, J.N.3
-
37
-
-
84864311450
-
Commensal bacteria calibrate the activation threshold of innate antiviral immunity
-
Abt MC, Osborne LC, Monticelli LA, Doering TA, Alenghat T, et al. (2012) Commensal bacteria calibrate the activation threshold of innate antiviral immunity. Immunity 37: 158-170.
-
(2012)
Immunity
, vol.37
, pp. 158-170
-
-
Abt, M.C.1
Osborne, L.C.2
Monticelli, L.A.3
Doering, T.A.4
Alenghat, T.5
-
38
-
-
80054867981
-
Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions
-
Hildebrand JM, Yi Z, Buchta CM, Poovassery J, Stunz LL, et al. (2011) Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions. Immunol Rev 244: 55-74.
-
(2011)
Immunol Rev
, vol.244
, pp. 55-74
-
-
Hildebrand, J.M.1
Yi, Z.2
Buchta, C.M.3
Poovassery, J.4
Stunz, L.L.5
-
39
-
-
82555193817
-
Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes
-
Xie P, Poovassery J, Stunz LL, Smith SM, Schultz ML, et al. (2011) Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes. J Leukoc Biol 90: 1149-1157.
-
(2011)
J Leukoc Biol
, vol.90
, pp. 1149-1157
-
-
Xie, P.1
Poovassery, J.2
Stunz, L.L.3
Smith, S.M.4
Schultz, M.L.5
-
40
-
-
34548014506
-
Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs
-
Xie P, Stunz LL, Larison KD, Yang B, Bishop GA, (2007) Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs. Immunity 27: 253-267.
-
(2007)
Immunity
, vol.27
, pp. 253-267
-
-
Xie, P.1
Stunz, L.L.2
Larison, K.D.3
Yang, B.4
Bishop, G.A.5
-
41
-
-
33748492573
-
Induction of RelB participates in endotoxin tolerance
-
Yoza BK, Hu JY, Cousart SL, Forrest LM, McCall CE, (2006) Induction of RelB participates in endotoxin tolerance. J Immunol 177: 4080-4085.
-
(2006)
J Immunol
, vol.177
, pp. 4080-4085
-
-
Yoza, B.K.1
Hu, J.Y.2
Cousart, S.L.3
Forrest, L.M.4
McCall, C.E.5
-
42
-
-
0027159611
-
Dissociation of lipopolysaccharide (LPS)-inducible gene expression in murine macrophages pretreated with smooth LPS versus monophosphoryl lipid A
-
Henricson BE, Manthey CL, Perera PY, Hamilton TA, Vogel SN, (1993) Dissociation of lipopolysaccharide (LPS)-inducible gene expression in murine macrophages pretreated with smooth LPS versus monophosphoryl lipid A. Infect Immun 61: 2325-2333.
-
(1993)
Infect Immun
, vol.61
, pp. 2325-2333
-
-
Henricson, B.E.1
Manthey, C.L.2
Perera, P.Y.3
Hamilton, T.A.4
Vogel, S.N.5
-
43
-
-
79952226160
-
The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo
-
Shirey KA, Nhu QM, Yim KC, Roberts ZJ, Teijaro JR, et al. (2011) The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo. J Leukoc Biol 89: 351-357.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 351-357
-
-
Shirey, K.A.1
Nhu, Q.M.2
Yim, K.C.3
Roberts, Z.J.4
Teijaro, J.R.5
-
44
-
-
0014122519
-
Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235
-
McIntire FC, Sievert HW, Barlow GH, Finley RA, Lee AY, (1967) Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235. Biochemistry 6: 2363-2372.
-
(1967)
Biochemistry
, vol.6
, pp. 2363-2372
-
-
McIntire, F.C.1
Sievert, H.W.2
Barlow, G.H.3
Finley, R.A.4
Lee, A.Y.5
-
45
-
-
47049118982
-
Measurement of antiviral activity induced by interferons alpha, beta, and gamma
-
Unit 6 9
-
Vogel SN, Friedman RM, Hogan MM, (2001) Measurement of antiviral activity induced by interferons alpha, beta, and gamma. Curr Protoc Immunol Chapter 6: Unit 6 9.
-
(2001)
Curr Protoc Immunol Chapter
, vol.6
-
-
Vogel, S.N.1
Friedman, R.M.2
Hogan, M.M.3
-
46
-
-
0028965256
-
Virus-neutralizing antibodies of immunoglobulin G (IgG) but not of IgM or IgA isotypes can cure influenza virus pneumonia in SCID mice
-
Palladino G, Mozdzanowska K, Washko G, Gerhard W, (1995) Virus-neutralizing antibodies of immunoglobulin G (IgG) but not of IgM or IgA isotypes can cure influenza virus pneumonia in SCID mice. J Virol 69: 2075-2081.
-
(1995)
J Virol
, vol.69
, pp. 2075-2081
-
-
Palladino, G.1
Mozdzanowska, K.2
Washko, G.3
Gerhard, W.4
-
47
-
-
34250803183
-
Role of phosphatidylinositol-3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fc gamma receptor ligation in murine macrophages
-
Polumuri SK, Toshchakov VY, Vogel SN, (2007) Role of phosphatidylinositol-3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fc gamma receptor ligation in murine macrophages. J Immunol 179: 236-246.
-
(2007)
J Immunol
, vol.179
, pp. 236-246
-
-
Polumuri, S.K.1
Toshchakov, V.Y.2
Vogel, S.N.3
-
48
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
|