Biotransformation of baicalin to baicalein significantly strengthens the inhibition potential towards UDP-glucuronosyltransferases (UGTs) isoforms

Pharmazie

Volumn 68, Issue 9, 2013, Pages 763-767

  Teng, Yanjie ^a,b   Nian, Hong ^a   Zhao, Hongtao ^a,b   Chen, Pei ^a,b   Wang, Guan ^a,b  

^a MUDANJIANG MEDICAL UNIVERSITY   (China)

^b Key Laboratory of Cancer Prevention and Treatment of Heilongjiang Province   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BAICALEIN; BAICALIN; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A6; GLUCURONOSYLTRANSFERASE 1A9; GLUCURONOSYLTRANSFERASE 2B7; HYMECROMONE; RECOMBINANT ENZYME;

ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG GLUCURONIDATION; DRUG MONITORING; DRUG TRANSFORMATION; ENZYME INHIBITION; IN VITRO STUDY; INHIBITION KINETICS; ISOMER;

BIOTRANSFORMATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLAVANONES; FLAVONOIDS; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HYMECROMONE; INDICATORS AND REAGENTS; ISOENZYMES; KINETICS; LIVER;

EID: 84884784998     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2013.2931     Document Type: Article

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