-
1
-
-
20344399217
-
-
American Academy of Sleep Medicine Chicago, IL: American Academy of Sleep Medicine Accessed June 4, 2013
-
American Academy of Sleep Medicine. International Classification of Sleep Disorders, Revised: Diagnostic and Coding Manual. Chicago, IL: American Academy of Sleep Medicine; 2001. http://www.esst.org/adds/ICSD.pdf. Accessed June 4, 2013.
-
(2001)
International Classification of Sleep Disorders, Revised: Diagnostic and Coding Manual
-
-
-
2
-
-
84869385705
-
Quality of life in patients suffering from insomnia
-
PubMed
-
Ishak WW, Bagot K, Thomas S, et al. Quality of life in patients suffering from insomnia. Innov Clin Neurosci. 2012;9(10):13-26. PubMed
-
(2012)
Innov Clin Neurosci
, vol.9
, Issue.10
, pp. 13-26
-
-
Ishak, W.W.1
Bagot, K.2
Thomas, S.3
-
3
-
-
29444444760
-
Prevalence, associated risks, and treatment patterns of insomnia
-
PubMed
-
Roth T. Prevalence, associated risks, and treatment patterns of insomnia. J Clin Psychiatry. 2005;66(suppl 9):10-13. PubMed
-
(2005)
J Clin Psychiatry
, vol.66
, Issue.SUPPL. 9
, pp. 10-13
-
-
Roth, T.1
-
4
-
-
0020368354
-
A two process model of sleep regulation
-
PubMed
-
Borbely AA. A two process model of sleep regulation. Hum Neurobiol. 1982;1(3):195-204. PubMed
-
(1982)
Hum Neurobiol
, vol.1
, Issue.3
, pp. 195-204
-
-
Borbely, A.A.1
-
5
-
-
27644457084
-
Hypothalamic regulation of sleep and circadian rhythms
-
doi:10.1038/nature04284 PubMed
-
Saper CB, Scammell TE, Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature. 2005;437(7063):1257-1263. doi:10.1038/nature04284 PubMed
-
(2005)
Nature
, vol.437
, Issue.7063
, pp. 1257-1263
-
-
Saper, C.B.1
Scammell, T.E.2
Lu, J.3
-
6
-
-
27744551591
-
Homeostatic, circadian, and emotional regulation of sleep
-
doi:10.102/cne.2070 PubMed
-
Saper CB, Cano G, Scammell TE. Homeostatic, circadian, and emotional regulation of sleep. J Comp Neurol. 2005;493(1):92-98. doi:10.102/cne.2070 PubMed
-
(2005)
J Comp Neurol
, vol.493
, Issue.1
, pp. 92-98
-
-
Saper, C.B.1
Cano, G.2
Scammell, T.E.3
-
7
-
-
0032402181
-
Neurons containing hypocretin (orexin) project to multiple neuronal systems
-
PubMed
-
Peyron C, Tighe DK, van den Pol AN, et al. Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci. 1998;18(23):9996- 10015. PubMed
-
(1998)
J Neurosci
, vol.18
, Issue.23
, pp. 9996-10015
-
-
Peyron, C.1
Tighe, D.K.2
Van Den Pol, A.N.3
-
8
-
-
33745512663
-
The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions
-
doi:10.1016/j.tips.206.05.06 PubMed
-
Zeitzer JM, Nishino S, Mignot E. The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions. Trends Pharmacol Sci. 2006;27(7):368-374. doi:10.1016/j.tips.206.05.06 PubMed
-
(2006)
Trends Pharmacol Sci
, vol.27
, Issue.7
, pp. 368-374
-
-
Zeitzer, J.M.1
Nishino, S.2
Mignot, E.3
-
9
-
-
0037509933
-
Circadian and homeostatic regulation of hypocretin in a primate model: Implications for the consolidation of wakefulness
-
PubMed
-
Zeitzer JM, Buckmaster CL, Parker KJ, et al. Circadian and homeostatic regulation of hypocretin in a primate model: implications for the consolidation of wakefulness. J Neurosci. 2003;23(8):3555-3560. PubMed
-
(2003)
J Neurosci
, vol.23
, Issue.8
, pp. 3555-3560
-
-
Zeitzer, J.M.1
Buckmaster, C.L.2
Parker, K.J.3
-
10
-
-
3042629187
-
Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release
-
PubMed
-
Zhang S, Zeitzer JM, Yoshida Y, et al. Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release. Sleep. 2004;27(4):619-627. PubMed
-
(2004)
Sleep
, vol.27
, Issue.4
, pp. 619-627
-
-
Zhang, S.1
Zeitzer, J.M.2
Yoshida, Y.3
-
11
-
-
84861842261
-
Cortical GABA levels in primary insomnia
-
PubMed
-
Morgan PT, Pace-Schott EF, Mason GF, et al. Cortical GABA levels in primary insomnia. Sleep. 2012;35(6):807-814. PubMed
-
(2012)
Sleep
, vol.35
, Issue.6
, pp. 807-814
-
-
Morgan, P.T.1
Pace-Schott, E.F.2
Mason, G.F.3
-
12
-
-
84859783895
-
Reduced ?-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: A link to major depressive disorder?
-
doi:10.1038/np.2012.4 PubMed
-
Plante DT, Jensen JE, Schoerning L, et al. Reduced ?-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder? Neuropsychopharmacology. 2012;37(6):1548-1557. doi:10.1038/np.2012.4 PubMed
-
(2012)
Neuropsychopharmacology
, vol.37
, Issue.6
, pp. 1548-1557
-
-
Plante, D.T.1
Jensen, J.E.2
Schoerning, L.3
-
13
-
-
33846979755
-
Promotion of sleep by targeting the orexin system in rats, dogs and humans
-
doi:10.1038/nm154 PubMed
-
Brisbare-Roch C, Dingemanse J, Koberstein R, et al. Promotion of sleep by targeting the orexin system in rats, dogs and humans. Nat Med. 2007;13(2):150-155. doi:10.1038/nm154 PubMed
-
(2007)
Nat Med
, vol.13
, Issue.2
, pp. 150-155
-
-
Brisbare-Roch, C.1
Dingemanse, J.2
Koberstein, R.3
-
14
-
-
0036838544
-
Hypocretin release in normal and narcoleptic dogs after food and sleep deprivation, eating, and movement
-
PubMed
-
Wu MF, John J, Maidment N, et al. Hypocretin release in normal and narcoleptic dogs after food and sleep deprivation, eating, and movement. Am J Physiol Regul Integr Comp Physiol. 2002;283(5):R1079-R1086. PubMed
-
(2002)
Am J Physiol Regul Integr Comp Physiol
, vol.283
, Issue.5
-
-
Wu, M.F.1
John, J.2
Maidment, N.3
-
15
-
-
19544376694
-
Behavioral correlates of activity in identified hypocretin/orexin neurons
-
doi:10.1016/j.neuron.205.04.035 PubMed
-
Mileykovskiy BY, Kiyashchenko LI, Siegel JM. Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron. 2005;46(5):787-798. doi:10.1016/j.neuron.205.04.035 PubMed
-
(2005)
Neuron
, vol.46
, Issue.5
, pp. 787-798
-
-
Mileykovskiy, B.Y.1
Kiyashchenko, L.I.2
Siegel, J.M.3
-
16
-
-
84875134387
-
Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction
-
doi:10.1038/ncoms2461 PubMed
-
Blouin AM, Fried I, Wilson CL, et al. Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction. Nat Commun. 2013;4:1547. doi:10.1038/ncoms2461 PubMed
-
(2013)
Nat Commun
, vol.4
, pp. 1547
-
-
Blouin, A.M.1
Fried, I.2
Wilson, C.L.3
-
17
-
-
55349132739
-
Clinical guideline for the evaluation and management of chronic insomnia in adults
-
PubMed
-
Schutte-Rodin S, Broch L, Buysse D, et al. Clinical guideline for the evaluation and management of chronic insomnia in adults. J Clin Sleep Med. 2008;4(5):487-504. PubMed
-
(2008)
J Clin Sleep Med
, vol.4
, Issue.5
, pp. 487-504
-
-
Schutte-Rodin, S.1
Broch, L.2
Buysse, D.3
-
18
-
-
33751115194
-
Practice parameters for the psychological and behavioral treatment of insomnia: An update
-
PubMed
-
Morgenthaler T, Kramer M, Alessi C, et al. Practice parameters for the psychological and behavioral treatment of insomnia: an update. An American Academy of Sleep Medicine report. Sleep. 2006;29(11):1415-1419. PubMed
-
(2006)
An American Academy of Sleep Medicine Report. Sleep
, vol.29
, Issue.11
, pp. 1415-1419
-
-
Morgenthaler, T.1
Kramer, M.2
Alessi, C.3
-
19
-
-
73249133013
-
"Stepped care": A health technology solution for delivering cognitive behavioral therapy as a first line insomnia treatment
-
PubMed
-
Espie CA. "Stepped care": a health technology solution for delivering cognitive behavioral therapy as a first line insomnia treatment. Sleep. 2009;32(12):1549-1558. PubMed
-
(2009)
Sleep
, vol.32
, Issue.12
, pp. 1549-1558
-
-
Espie, C.A.1
-
20
-
-
0035843629
-
Cognitive behavioral therapy for treatment of chronic primary insomnia: A randomized controlled trial
-
doi:10.101/jama.285.14.1856 PubMed
-
Edinger JD, Wohlgemuth WK, Radtke RA, et al. Cognitive behavioral therapy for treatment of chronic primary insomnia: a randomized controlled trial. JAMA. 2001;285(14):1856-1864. doi:10.101/jama.285.14.1856 PubMed
-
(2001)
JAMA
, vol.285
, Issue.14
, pp. 1856-1864
-
-
Edinger, J.D.1
Wohlgemuth, W.K.2
Radtke, R.A.3
-
21
-
-
0035238972
-
The clinical effectiveness of cognitive behaviour therapy for chronic insomnia: Implementation and evaluation of a sleep clinic in general medical practice
-
doi:10.1016/S05-7967(9)0157-6 PubMed
-
Espie CA, Inglis SJ, Tessier S, et al. The clinical effectiveness of cognitive behaviour therapy for chronic insomnia: implementation and evaluation of a sleep clinic in general medical practice. Behav Res Ther. 2001;39(1):45-60. doi:10.1016/S05-7967(9)0157-6 PubMed
-
(2001)
Behav Res Ther
, vol.39
, Issue.1
, pp. 45-60
-
-
Espie, C.A.1
Inglis, S.J.2
Tessier, S.3
-
22
-
-
33751083841
-
Psychological and behavioral treatment of insomnia: Update of the recent evidence (1998-2004)
-
PubMed
-
Morin CM, Bootzin RR, Buysse DJ, et al. Psychological and behavioral treatment of insomnia: update of the recent evidence (1998-2004). Sleep. 2006;29(11):1398-1414. PubMed
-
(2006)
Sleep
, vol.29
, Issue.11
, pp. 1398-1414
-
-
Morin, C.M.1
Bootzin, R.R.2
Buysse, D.J.3
-
24
-
-
84878379048
-
Review of the histamine system and the clinical effects of H1 antagonists: Basis for a new model for understanding the effects of insomnia medications
-
doi:10.1016/j.smrv.2012.08.01 PubMed
-
Krystal AD, Richelson E, Roth T. Review of the histamine system and the clinical effects of H1 antagonists: basis for a new model for understanding the effects of insomnia medications. Sleep Med Rev. 2013;17(4):263-272. doi:10.1016/j.smrv.2012.08.01 PubMed
-
(2013)
Sleep Med Rev
, vol.17
, Issue.4
, pp. 263-272
-
-
Krystal, A.D.1
Richelson, E.2
Roth, T.3
-
26
-
-
0029382853
-
Nocturnal plasma melatonin levels in patients suffering from chronic primary insomnia
-
doi:10.1/j.160-079X.195.tb0179.x PubMed
-
Hajak G, Rodenbeck A, Staedt J, et al. Nocturnal plasma melatonin levels in patients suffering from chronic primary insomnia. J Pineal Res. 1995;19(3):116-122. doi:10.1/j.160-079X.195.tb0179.x PubMed
-
(1995)
J Pineal Res
, vol.19
, Issue.3
, pp. 116-122
-
-
Hajak, G.1
Rodenbeck, A.2
Staedt, J.3
-
27
-
-
84877862583
-
Meta-analysis: Melatonin for the treatment of primary sleep disorders
-
doi:10.1371/journal.pone.06373 PubMed
-
Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS ONE. 2013;8(5):e63773. doi:10.1371/journal.pone.06373 PubMed
-
(2013)
PLoS ONE
, vol.8
, Issue.5
-
-
Ferracioli-Oda, E.1
Qawasmi, A.2
Bloch, M.H.3
-
28
-
-
84858848359
-
Prolonged-release formulation of melatonin (Circadin) for the treatment of insomnia
-
doi:10.1517/1465656.2012.67076 PubMed
-
Lemoine P, Zisapel N. Prolonged-release formulation of melatonin (Circadin) for the treatment of insomnia. Expert Opin Pharmacother. 2012;13(6):895-905. doi:10.1517/1465656.2012.67076 PubMed
-
(2012)
Expert Opin Pharmacother
, vol.13
, Issue.6
, pp. 895-905
-
-
Lemoine, P.1
Zisapel, N.2
-
29
-
-
79951771562
-
A systematic review of insomnia and complementary medicine
-
doi:10.1016/j.smrv.2010.04.01 PubMed
-
Sarris J, Byrne GJ. A systematic review of insomnia and complementary medicine. Sleep Med Rev. 2011;15(2):99-106. doi:10.1016/j.smrv.2010.04.01 PubMed
-
(2011)
Sleep Med Rev
, vol.15
, Issue.2
, pp. 99-106
-
-
Sarris, J.1
Byrne, G.J.2
-
30
-
-
38949166904
-
Complementary and alternative medicine for sleep disturbances in older adults
-
viii doi:10.1016/j.cger.207.08.02 PubMed
-
Gooneratne NS. Complementary and alternative medicine for sleep disturbances in older adults. Clin Geriatr Med. 2008;24(1):121-138, viii. doi:10.1016/j.cger.207.08.02 PubMed
-
(2008)
Clin Geriatr Med
, vol.24
, Issue.1
, pp. 121-138
-
-
Gooneratne, N.S.1
-
31
-
-
34248544974
-
A systematic review of valerian as a sleep aid: Safe but not effective
-
doi:10.1016/j.smrv.207.03.02 PubMed
-
Taibi DM, Landis CA, Petry H, et al. A systematic review of valerian as a sleep aid: safe but not effective. Sleep Med Rev. 2007;11(3):209-230. doi:10.1016/j.smrv.207.03.02 PubMed
-
(2007)
Sleep Med Rev
, vol.11
, Issue.3
, pp. 209-230
-
-
Taibi, D.M.1
Landis, C.A.2
Petry, H.3
-
32
-
-
79551515048
-
-
San Diego, CA: Somaxon Pharmaceuticals, Inc
-
Silenor (doxepin) [package insert]. San Diego, CA: Somaxon Pharmaceuticals, Inc; 2010.
-
(2010)
Silenor (Doxepin) [Package Insert]
-
-
-
33
-
-
84884807634
-
-
Sellersville, PA: Teva Pharmaceuticals USA
-
Estazolam [package insert]. Sellersville, PA: Teva Pharmaceuticals USA; 2008.
-
(2008)
Estazolam [Package Insert]
-
-
-
34
-
-
84884734000
-
-
Marlborough, MA: Sunovion Pharmaceuticals Inc
-
Lunesta (eszopiclone) [package insert]. Marlborough, MA: Sunovion Pharmaceuticals Inc; 2012.
-
(2012)
Lunesta (Eszopiclone) [Package Insert]
-
-
-
35
-
-
84884735305
-
-
Libertyville, IL: A-S Medical Solutions
-
Flurazepam [package insert]. Libertyville, IL: A-S Medical Solutions; 2010.
-
(2010)
Flurazepam [Package Insert]
-
-
-
36
-
-
84884779965
-
-
Hayward, CA: Questor Pharmaceuticals, Inc
-
Doral (quazepam) [package insert]. Hayward, CA: Questor Pharmaceuticals, Inc; 2013.
-
(2013)
Doral (Quazepam) [Package Insert]
-
-
-
37
-
-
84884780907
-
-
Deerfield, IL: Takeda Pharmaceuticals America, Inc
-
Rozerem (ramelteon) [package insert]. Deerfield, IL: Takeda Pharmaceuticals America, Inc; 2010.
-
(2010)
Rozerem (Ramelteon) [Package Insert]
-
-
-
40
-
-
84884749970
-
-
Bristol, TN: King Pharmaceuticals, Inc
-
Sonata (zaleplon) [package insert]. Bristol, TN: King Pharmaceuticals, Inc; 2011.
-
(2011)
Sonata (Zaleplon) [Package Insert]
-
-
-
41
-
-
84884768714
-
-
Bridgewater, NJ: sanofi-aventis US LLC
-
Ambien (zolpidem) [package insert]. Bridgewater, NJ: sanofi-aventis US LLC; 2013.
-
(2013)
Ambien (Zolpidem) [Package Insert]
-
-
-
44
-
-
63849263095
-
Drugs for insomnia
-
PubMed
-
Drugs for insomnia. Treat Guidel Med Lett. 2009;7(79):23-26. PubMed
-
(2009)
Treat Guidel Med Lett
, vol.7
, Issue.79
, pp. 23-26
-
-
-
45
-
-
84877969362
-
Eszopiclone treatment for insomnia: Effect size comparisons in patients with primary insomnia and insomnia with medical and psychiatric comorbidity
-
doi:10.4088/pcc.11m01296 PubMed
-
Krystal AD, McCall WV, Fava M, et al. Eszopiclone treatment for insomnia: effect size comparisons in patients with primary insomnia and insomnia with medical and psychiatric comorbidity. Prim Care Companion CNS Disord. 2012;14(4):doi:10.4088/ pcc.11m01296. PubMed
-
(2012)
Prim Care Companion CNS Disord
, vol.14
, Issue.4
-
-
Krystal, A.D.1
McCall, W.V.2
Fava, M.3
-
46
-
-
84873363660
-
Novel sublingual low-dose zolpidem tablet reduces latency to sleep onset following spontaneous middle-of-the-night awakening in insomnia in a randomized, double-blind, placebo-controlled, outpatient study
-
PubMed
-
Roth T, Krystal A, Steinberg FJ, et al. Novel sublingual low-dose zolpidem tablet reduces latency to sleep onset following spontaneous middle-of-the-night awakening in insomnia in a randomized, double-blind, placebo-controlled, outpatient study. Sleep. 2013;36(2):189-196. PubMed
-
(2013)
Sleep
, vol.36
, Issue.2
, pp. 189-196
-
-
Roth, T.1
Krystal, A.2
Steinberg, F.J.3
-
47
-
-
34548485598
-
Evaluation of the efficacy and safety of ramelteon in subjects with chronic insomnia
-
PubMed
-
Zammit G, Erman M, Wang-Weigand S, et al. Evaluation of the efficacy and safety of ramelteon in subjects with chronic insomnia. J Clin Sleep Med. 2007;3(5):495-504. PubMed
-
(2007)
J Clin Sleep Med
, vol.3
, Issue.5
, pp. 495-504
-
-
Zammit, G.1
Erman, M.2
Wang-Weigand, S.3
-
48
-
-
29844447353
-
An efficacy, safety, and dose-response study of Ramelteon in patients with chronic primary insomnia
-
doi:10.1016/j.slep.205.09.04 PubMed
-
Erman M, Seiden D, Zammit G, et al. An efficacy, safety, and dose-response study of Ramelteon in patients with chronic primary insomnia. Sleep Med. 2006;7(1):17-24. doi:10.1016/j.slep.205.09.04 PubMed
-
(2006)
Sleep Med
, vol.7
, Issue.1
, pp. 17-24
-
-
Erman, M.1
Seiden, D.2
Zammit, G.3
-
49
-
-
34548249175
-
Efficacy and safety of doxepin 1 mg, 3 mg, and 6 mg in adults with primary insomnia
-
PubMed
-
Roth T, Rogowski R, Hull S, et al. Efficacy and safety of doxepin 1 mg, 3 mg, and 6 mg in adults with primary insomnia. Sleep. 2007;30(11):1555-1561. PubMed
-
(2007)
Sleep
, vol.30
, Issue.11
, pp. 1555-1561
-
-
Roth, T.1
Rogowski, R.2
Hull, S.3
-
50
-
-
54949128640
-
Efficacy and safety of doxepin 1 mg, 3 mg, and 6 mg in elderly patients with primary insomnia: A randomized, double-blind, placebo-controlled crossover study
-
doi:10.408/JCP.v69n105 PubMed
-
Scharf M, Rogowski R, Hull S, et al. Efficacy and safety of doxepin 1 mg, 3 mg, and 6 mg in elderly patients with primary insomnia: a randomized, double-blind, placebo-controlled crossover study. J Clin Psychiatry. 2008;69(10):1557-1564. doi:10.408/JCP.v69n105 PubMed
-
(2008)
J Clin Psychiatry
, vol.69
, Issue.10
, pp. 1557-1564
-
-
Scharf, M.1
Rogowski, R.2
Hull, S.3
-
52
-
-
17844392614
-
A review of the evidence for the efficacy and safety of trazodone in insomnia
-
doi:10.408/JCP.v6n0409 PubMed
-
Mendelson WB. A review of the evidence for the efficacy and safety of trazodone in insomnia. J Clin Psychiatry. 2005;66(4):469-476. doi:10.408/JCP.v6n0409 PubMed
-
(2005)
J Clin Psychiatry
, vol.66
, Issue.4
, pp. 469-476
-
-
Mendelson, W.B.1
-
53
-
-
84884779642
-
Histamine-1 receptor antagonism for treatment of insomnia
-
doi:10.131/JAPhA.2012.12051 PubMed
-
Vande Griend JP, Anderson SL. Histamine-1 receptor antagonism for treatment of insomnia. J Am Pharm Assoc (2003). 2012;52(6):e210-e219. doi:10.131/JAPhA.2012.12051 PubMed
-
(2012)
J Am Pharm Assoc (2003)
, vol.52
, Issue.6
-
-
Vande Griend, J.P.1
Anderson, S.L.2
-
54
-
-
25444533069
-
Atypical antipsychotics: Sleep, sedation, and efficacy
-
PubMed
-
Miller DD. Atypical antipsychotics: sleep, sedation, and efficacy. Prim Care Companion J Clin Psychiatry. 2004;6(suppl 2):3-7. PubMed
-
(2004)
Prim Care Companion J Clin Psychiatry
, vol.6
, Issue.SUPPL. 2
, pp. 3-7
-
-
Miller, D.D.1
-
55
-
-
84870814425
-
What is the role of sedating antidepressants, antipsychotics, and anticonvulsants in the management of insomnia?
-
doi:10.107/s1920-012-0302-y PubMed
-
McCall C, McCall WV. What is the role of sedating antidepressants, antipsychotics, and anticonvulsants in the management of insomnia? Curr Psychiatry Rep. 2012;14(5):494-502. doi:10.107/s1920-012-0302-y PubMed
-
(2012)
Curr Psychiatry Rep
, vol.14
, Issue.5
, pp. 494-502
-
-
McCall, C.1
McCall, W.V.2
-
56
-
-
34548765427
-
Management of insomnia: Treatments and mechanisms
-
doi:10.192/bjp.bp.107.036301 PubMed
-
Wilson S, Nutt D. Management of insomnia: treatments and mechanisms. Br J Psychiatry. 2007;191(3):195-197. doi:10.192/bjp.bp.107.036301 PubMed
-
(2007)
Br J Psychiatry
, vol.191
, Issue.3
, pp. 195-197
-
-
Wilson, S.1
Nutt, D.2
-
57
-
-
77949666623
-
Adverse effects of antipsychotic medications
-
PubMed
-
Muench J, Hamer AM. Adverse effects of antipsychotic medications. Am Fam Physician. 2010;81(5):617-622. PubMed
-
(2010)
Am Fam Physician
, vol.81
, Issue.5
, pp. 617-622
-
-
Muench, J.1
Hamer, A.M.2
-
58
-
-
79959501407
-
Amperometric measurement of glutamate release modulation by gabapentin and pregabalin in rat neocortical slices: Role of voltage-sensitive Ca2+ a2d-1 subunit
-
doi:10.124/jpet.10.178384 PubMed
-
Quintero JE, Dooley DJ, Pomerleau F, et al. Amperometric measurement of glutamate release modulation by gabapentin and pregabalin in rat neocortical slices: role of voltage-sensitive Ca2+ a2d-1 subunit. J Pharmacol Exp Ther. 2011;338(1):240-245. doi:10.124/jpet.10.178384 PubMed
-
(2011)
J Pharmacol Exp Ther
, vol.338
, Issue.1
, pp. 240-245
-
-
Quintero, J.E.1
Dooley, D.J.2
Pomerleau, F.3
-
60
-
-
0042367510
-
GABA, gamma-hydroxybutyric acid, and neurological disease
-
doi:10.102/ana.10696 PubMed
-
Wong CG, Bottiglieri T, Snead OC 3rd. GABA, gamma-hydroxybutyric acid, and neurological disease. Ann Neurol. 2003;54(suppl 6):S3-S12. doi:10.102/ana.10696 PubMed
-
(2003)
Ann Neurol
, vol.54
, Issue.SUPPL. 6
-
-
Wong, C.G.1
Bottiglieri, T.2
Snead III, O.C.3
-
61
-
-
34548496295
-
The evolution and development of insomnia pharmacotherapies
-
PubMed
-
Neubauer DN. The evolution and development of insomnia pharmacotherapies. J Clin Sleep Med. 2007;3(suppl):S11-S15. PubMed
-
(2007)
J Clin Sleep Med
, vol.3
, Issue.SUPPL.
-
-
Neubauer, D.N.1
-
62
-
-
0035186421
-
New insights into the role of the GABA(A)-benzodiazepine receptor in psychiatric disorder
-
doi:10.192/bjp.179.5.390 PubMed
-
Nutt DJ, Malizia AL. New insights into the role of the GABA(A)-benzodiazepine receptor in psychiatric disorder. Br J Psychiatry. 2001;179(5):390-396. doi:10.192/bjp.179.5.390 PubMed
-
(2001)
Br J Psychiatry
, vol.179
, Issue.5
, pp. 390-396
-
-
Nutt, D.J.1
Malizia, A.L.2
-
63
-
-
0036673411
-
Subunit composition, distribution and function of GABA(A) receptor subtypes
-
doi:10.2174/156802602393507 PubMed
-
Sieghart W, Sperk G. Subunit composition, distribution and function of GABA(A) receptor subtypes. Curr Top Med Chem. 2002;2(8):795-816. doi:10.2174/156802602393507 PubMed
-
(2002)
Curr Top Med Chem
, vol.2
, Issue.8
, pp. 795-816
-
-
Sieghart, W.1
Sperk, G.2
-
64
-
-
0034139797
-
Recent advances in GABAB receptors: From pharmacology to molecular biology
-
PubMed
-
Ong J, Kerr DI. Recent advances in GABAB receptors: from pharmacology to molecular biology. Acta Pharmacol Sin. 2000;21(2):111-123. PubMed
-
(2000)
Acta Pharmacol Sin
, vol.21
, Issue.2
, pp. 111-123
-
-
Ong, J.1
Kerr, D.I.2
-
65
-
-
0037052652
-
GABA mechanisms and sleep
-
doi:10.1016/S0306-452(02)034-9 PubMed
-
Gottesmann C. GABA mechanisms and sleep. Neuroscience. 2002;111(2):231-239. doi:10.1016/S0306-452(02)034-9 PubMed
-
(2002)
Neuroscience
, vol.111
, Issue.2
, pp. 231-239
-
-
Gottesmann, C.1
-
66
-
-
0034711768
-
Meta-analysis of benzodiazepine use in the treatment of insomnia
-
PubMed
-
Holbrook AM, Crowther R, Lotter A, et al. Meta-analysis of benzodiazepine use in the treatment of insomnia. CMAJ. 2000;162(2):225-233. PubMed
-
(2000)
CMAJ
, vol.162
, Issue.2
, pp. 225-233
-
-
Holbrook, A.M.1
Crowther, R.2
Lotter, A.3
-
67
-
-
84872360883
-
Effectiveness of nonbenzodiazepine hypnotics in treatment of adult insomnia: Meta-analysis of data submitted to the Food and Drug Administration
-
doi:10.136/bmj.e8343 PubMed
-
Huedo-Medina TB, Kirsch I, Middlemass J, et al. Effectiveness of nonbenzodiazepine hypnotics in treatment of adult insomnia: meta-analysis of data submitted to the Food and Drug Administration. BMJ. 2012;345(6):e8343. doi:10.136/bmj.e8343 PubMed
-
(2012)
BMJ
, vol.345
, Issue.6
-
-
Huedo-Medina, T.B.1
Kirsch, I.2
Middlemass, J.3
-
68
-
-
37549026159
-
Long-term efficacy and safety of zolpidem extended-release 12.5 mg, administered 3 to 7 nights per week for 24 weeks, in patients with chronic primary insomnia: A 6-month, randomized, double-blind, placebo-controlled, parallel-group, multicenter study
-
for the ZOLONG Study Group PubMed
-
Krystal AD, Erman M, Zammit GK, et al, for the ZOLONG Study Group. Long-term efficacy and safety of zolpidem extended-release 12.5 mg, administered 3 to 7 nights per week for 24 weeks, in patients with chronic primary insomnia: a 6-month, randomized, double-blind, placebo-controlled, parallel-group, multicenter study. Sleep. 2008;31(1):79-90. PubMed
-
(2008)
Sleep
, vol.31
, Issue.1
, pp. 79-90
-
-
Krystal, A.D.1
Erman, M.2
Zammit, G.K.3
-
69
-
-
1842463058
-
Sustained efficacy of eszopiclone over 6 months of nightly treatment: Results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia
-
PubMed
-
Krystal AD, Walsh JK, Laska E, et al. Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia. Sleep. 2003;26(7):793-799. PubMed
-
(2003)
Sleep
, vol.26
, Issue.7
, pp. 793-799
-
-
Krystal, A.D.1
Walsh, J.K.2
Laska, E.3
-
70
-
-
84864753130
-
Differential effects of sodium oxybate and baclofen on EEG, sleep, neurobehavioral performance, and memory
-
PubMed
-
Vienne J, Lecciso G, Constantinescu I, et al. Differential effects of sodium oxybate and baclofen on EEG, sleep, neurobehavioral performance, and memory. Sleep. 2012;35(8):1071-1083. PubMed
-
(2012)
Sleep
, vol.35
, Issue.8
, pp. 1071-1083
-
-
Vienne, J.1
Lecciso, G.2
Constantinescu, I.3
-
71
-
-
33845479670
-
Gamma-Hydroxybutyrate/sodium oxybate: Neurobiology, and impact on sleep and wakefulness
-
doi:10.2165/023210-20620120-04 PubMed
-
Pardi D, Black J. gamma-Hydroxybutyrate/sodium oxybate: neurobiology, and impact on sleep and wakefulness. CNS Drugs. 2006;20(12):993-1018. doi:10.2165/023210-20620120-04 PubMed
-
(2006)
CNS Drugs
, vol.20
, Issue.12
, pp. 993-1018
-
-
Pardi, D.1
Black, J.2
-
72
-
-
0034387887
-
Gamma-hydroxybutyrate (GHB): A newer drug of abuse
-
PubMed
-
O'Connell T, Kaye L, Plosay JJ 3rd. Gamma-hydroxybutyrate (GHB): a newer drug of abuse. Am Fam Physician. 2000;62(11):2478-2483. PubMed
-
(2000)
Am Fam Physician
, vol.62
, Issue.11
, pp. 2478-2483
-
-
O'connell, T.1
Kaye, L.2
Plosay III, J.J.3
-
73
-
-
0028798696
-
The effects of the GABA agonist, baclofen, on sleep and breathing
-
doi:10.183/09031936.95.08020230 PubMed
-
Finnimore AJ, Roebuck M, Sajkov D, et al. The effects of the GABA agonist, baclofen, on sleep and breathing. Eur Respir J. 1995;8(2):230-234. doi:10.183/09031936.95.08020230 PubMed
-
(1995)
Eur Respir J
, vol.8
, Issue.2
, pp. 230-234
-
-
Finnimore, A.J.1
Roebuck, M.2
Sajkov, D.3
-
74
-
-
84861194666
-
The effect of baclofen on nocturnal gastroesophageal reflux and measures of sleep quality: A randomized, cross-over trial
-
e253 doi:10.1/j.1365-2982.2012.0190.x PubMed
-
Orr WC, Goodrich S, Wright S, et al. The effect of baclofen on nocturnal gastroesophageal reflux and measures of sleep quality: a randomized, cross-over trial. Neurogastroenterol Motil. 2012;24(6):553-559, e253. doi:10.1/j.1365-2982. 2012.0190.x PubMed
-
(2012)
Neurogastroenterol Motil
, vol.24
, Issue.6
, pp. 553-559
-
-
Orr, W.C.1
Goodrich, S.2
Wright, S.3
-
75
-
-
65349165284
-
Enhancement of slow wave sleep: Implications for insomnia
-
PubMed
-
Walsh JK. Enhancement of slow wave sleep: implications for insomnia. J Clin Sleep Med. 2009;5(suppl):S27-S32. PubMed
-
(2009)
J Clin Sleep Med
, vol.5
, Issue.SUPPL.
-
-
Walsh, J.K.1
-
76
-
-
0035115746
-
The GABA uptake inhibitor tiagabine promotes slow wave sleep in normal elderly subjects
-
doi:10.1016/S0197-4580(0)0232-3 PubMed
-
Mathias S, Wetter TC, Steiger A, et al. The GABA uptake inhibitor tiagabine promotes slow wave sleep in normal elderly subjects. Neurobiol Aging. 2001;22(2):247-253. doi:10.1016/S0197-4580(0)0232-3 PubMed
-
(2001)
Neurobiol Aging
, vol.22
, Issue.2
, pp. 247-253
-
-
Mathias, S.1
Wetter, T.C.2
Steiger, A.3
-
77
-
-
0008390266
-
The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity
-
doi:10.1073/pnas.95.1.32 PubMed
-
de Lecea L, Kilduff TS, Peyron C, et al. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A. 1998;95(1):322-327. doi:10.1073/pnas.95.1.32 PubMed
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.1
, pp. 322-327
-
-
De Lecea, L.1
Kilduff, T.S.2
Peyron, C.3
-
78
-
-
20244380014
-
Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
doi:10.1016/S092-8674(0)80949-6 PubMed
-
Sakurai T, Amemiya A, Ishii M, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 1998;92(4):573-585. doi:10.1016/S092-8674(0) 80949-6 PubMed
-
(1998)
Cell
, vol.92
, Issue.4
, pp. 573-585
-
-
Sakurai, T.1
Amemiya, A.2
Ishii, M.3
-
79
-
-
0033710848
-
Reduced number of hypocretin neurons in human narcolepsy
-
doi:10.1016/S0896-6273(0)058-1 PubMed
-
Thannickal TC, Moore RY, Nienhuis R, et al. Reduced number of hypocretin neurons in human narcolepsy. Neuron. 2000;27(3):469-474. doi:10.1016/S0896- 6273(0)058-1 PubMed
-
(2000)
Neuron
, vol.27
, Issue.3
, pp. 469-474
-
-
Thannickal, T.C.1
Moore, R.Y.2
Nienhuis, R.3
-
80
-
-
0033826856
-
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
-
doi:10.1038/79690 PubMed
-
Peyron C, Faraco J, Rogers W, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med. 2000;6(9):991-997. doi:10.1038/79690 PubMed
-
(2000)
Nat Med
, vol.6
, Issue.9
, pp. 991-997
-
-
Peyron, C.1
Faraco, J.2
Rogers, W.3
-
81
-
-
85012124441
-
-
National Institute of Neurological Disorders and Stroke Updated December 28, 2011. Accessed June 4
-
National Institute of Neurological Disorders and Stroke. Narcolepsy Fact Sheet. http://www.ninds.nih.gov/disorders/narcolepsy/detail-narcolepsy.htm. Updated December 28, 2011. Accessed June 4, 2013.
-
(2013)
Narcolepsy Fact Sheet
-
-
-
82
-
-
0033529520
-
The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
-
doi:10.1016/S092-8674(0)81965-0 PubMed
-
Lin L, Faraco J, Li R, et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell. 1999;98(3):365-376. doi:10.1016/S092-8674(0)81965-0 PubMed
-
(1999)
Cell
, vol.98
, Issue.3
, pp. 365-376
-
-
Lin, L.1
Faraco, J.2
Li, R.3
-
83
-
-
0033588184
-
Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
-
doi:10.1016/S092-8674(0)81973-X PubMed
-
Chemelli RM, Willie JT, Sinton CM, et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell. 1999;98(4):437-451. doi:10.1016/S092-8674(0)81973-X PubMed
-
(1999)
Cell
, vol.98
, Issue.4
, pp. 437-451
-
-
Chemelli, R.M.1
Willie, J.T.2
Sinton, C.M.3
-
84
-
-
0036791834
-
The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias
-
doi:10.101/archneur.59.10.153 PubMed
-
Mignot E, Lammers GJ, Ripley B, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol. 2002;59(10):1553-1562. doi:10.101/archneur.59.10.153 PubMed
-
(2002)
Arch Neurol
, vol.59
, Issue.10
, pp. 1553-1562
-
-
Mignot, E.1
Lammers, G.J.2
Ripley, B.3
-
85
-
-
67649448978
-
Orexin/hypocretin: A neuropeptide at the interface of sleep, energy homeostasis, and reward system
-
doi:10.124/pr.109.01321 PubMed
-
Tsujino N, Sakurai T. Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system. Pharmacol Rev. 2009;61(2):162-176. doi:10.124/pr.109.01321 PubMed
-
(2009)
Pharmacol Rev
, vol.61
, Issue.2
, pp. 162-176
-
-
Tsujino, N.1
Sakurai, T.2
-
86
-
-
79951994324
-
Orexin receptors: Pharmacology and therapeutic opportunities
-
doi:10.146/anurev-pharmtox-010510-10528 PubMed
-
Scammell TE, Winrow CJ. Orexin receptors: pharmacology and therapeutic opportunities. Annu Rev Pharmacol Toxicol. 2011;51(1):243-266. doi:10.146/anurev-pharmtox-010510-10528 PubMed
-
(2011)
Annu Rev Pharmacol Toxicol
, vol.51
, Issue.1
, pp. 243-266
-
-
Scammell, T.E.1
Winrow, C.J.2
-
87
-
-
84884785732
-
-
Published January 28, 2011. Accessed June 5
-
Actelion. Actelion and GSK discontinue clinical development of almorexant. http://www1.actelion.com/en/our-company/news-and-events/index. page?newsId=1483135. Published January 28, 2011. Accessed June 5, 2013.
-
(2013)
Actelion and GSK Discontinue Clinical Development of Almorexant
-
-
-
88
-
-
67749103988
-
Discovery of a potent, CNS-penetrant orexin receptor antagonist based on an n,n-disubstituted-1,4-diazepane scaffold that promotes sleep in rats
-
doi:10.102/cmdc.209069 PubMed
-
Whitman DB, Cox CD, Breslin MJ, et al. Discovery of a potent, CNS-penetrant orexin receptor antagonist based on an n,n-disubstituted-1,4- diazepane scaffold that promotes sleep in rats. Chem Med Chem. 2009;4(7):1069-1074. doi:10.102/cmdc.209069 PubMed
-
(2009)
Chem Med Chem
, vol.4
, Issue.7
, pp. 1069-1074
-
-
Whitman, D.B.1
Cox, C.D.2
Breslin, M.J.3
-
89
-
-
84871323368
-
Orexin receptor antagonism for treatment of insomnia: A randomized clinical trial of suvorexant
-
doi:10.1212/WNL.0b013e3182768e PubMed
-
Herring WJ, Snyder E, Budd K, et al. Orexin receptor antagonism for treatment of insomnia: a randomized clinical trial of suvorexant. Neurology. 2012;79(23):2265-2274. doi:10.1212/WNL.0b013e3182768e PubMed
-
(2012)
Neurology
, vol.79
, Issue.23
, pp. 2265-2274
-
-
Herring, W.J.1
Snyder, E.2
Budd, K.3
-
90
-
-
84873388862
-
Effects of suvorexant, an orexin receptor antagonist, on sleep parameters as measured by polysomnography in healthy men
-
PubMed
-
Sun H, Kennedy WP, Wilbraham D, et al. Effects of suvorexant, an orexin receptor antagonist, on sleep parameters as measured by polysomnography in healthy men. Sleep. 2013;36(2):259-267. PubMed
-
(2013)
Sleep
, vol.36
, Issue.2
, pp. 259-267
-
-
Sun, H.1
Kennedy, W.P.2
Wilbraham, D.3
-
91
-
-
84891275537
-
Discovery and development of orexin receptor antagonists as therapeutics for insomnia [published online ahead of print June 3, 2013]
-
doi:10.1111/bph.12261. doi:10.1/bph.1261 PubMed
-
Winrow CJ, Renger JJ. Discovery and development of orexin receptor antagonists as therapeutics for insomnia [published online ahead of print June 3, 2013]. Br J Pharmacol. doi:10.1111/bph.12261. doi:10.1/bph.1261 PubMed
-
Br J Pharmacol
-
-
Winrow, C.J.1
Renger, J.J.2
-
92
-
-
84864118879
-
Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist
-
doi:10.17/026981408954 PubMed
-
Bettica P, Nucci G, Pyke C, et al. Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist. J Psychopharmacol. 2012;26(8):1058-1070. doi:10.17/026981408954 PubMed
-
(2012)
J Psychopharmacol
, vol.26
, Issue.8
, pp. 1058-1070
-
-
Bettica, P.1
Nucci, G.2
Pyke, C.3
-
93
-
-
84864766771
-
The orexin antagonist SB-649868 promotes and maintains sleep in men with primary insomnia
-
PubMed
-
Bettica P, Squassante L, Zamuner S, et al. The orexin antagonist SB-649868 promotes and maintains sleep in men with primary insomnia. Sleep. 2012;35(8):1097-1104. PubMed
-
(2012)
Sleep
, vol.35
, Issue.8
, pp. 1097-1104
-
-
Bettica, P.1
Squassante, L.2
Zamuner, S.3
-
94
-
-
67649867893
-
Blockade of orexin-1 receptors attenuates orexin-2 receptor antagonism-induced sleep promotion in the rat
-
doi:10.124/jpet.109.15209 PubMed
-
Dugovic C, Shelton JE, Aluisio LE, et al. Blockade of orexin-1 receptors attenuates orexin-2 receptor antagonism-induced sleep promotion in the rat. J Pharmacol Exp Ther. 2009;330(1):142-151. doi:10.124/jpet.109.15209 PubMed
-
(2009)
J Pharmacol Exp Ther
, vol.330
, Issue.1
, pp. 142-151
-
-
Dugovic, C.1
Shelton, J.E.2
Aluisio, L.E.3
-
95
-
-
84863614156
-
Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone
-
doi:10.1371/journal.pone.039131 PubMed
-
Morairty SR, Revel FG, Malherbe P, et al. Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone. PLoS ONE. 2012;7(7):e39131. doi:10.1371/journal.pone.039131 PubMed
-
(2012)
PLoS ONE
, vol.7
, Issue.7
-
-
Morairty, S.R.1
Revel, F.G.2
Malherbe, P.3
-
96
-
-
0038724250
-
Distinct narcolepsy syndromes in orexin receptor-2 and orexin null mice: Molecular genetic dissection of Non-REM and REM sleep regulatory processes
-
doi:10.1016/S0896-6273(03)030-1 PubMed
-
Willie JT, Chemelli RM, Sinton CM, et al. Distinct narcolepsy syndromes in orexin receptor-2 and orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes. Neuron. 2003;38(5):715-730. doi:10.1016/S0896-6273(03)030-1 PubMed
-
(2003)
Neuron
, vol.38
, Issue.5
, pp. 715-730
-
-
Willie, J.T.1
Chemelli, R.M.2
Sinton, C.M.3
-
97
-
-
84874611179
-
Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy
-
PubMed
-
Black SW, Morairty SR, Fisher SP, et al. Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy. Sleep. 2013;36(3):325-336. PubMed
-
(2013)
Sleep
, vol.36
, Issue.3
, pp. 325-336
-
-
Black, S.W.1
Morairty, S.R.2
Fisher, S.P.3
-
98
-
-
70649101313
-
Body mass index-independent metabolic alterations in narcolepsy with cataplexy
-
PubMed
-
Poli F, Plazzi G, Di Dalmazi G, et al. Body mass index-independent metabolic alterations in narcolepsy with cataplexy. Sleep. 2009;32(11):1491- 1497. PubMed
-
(2009)
Sleep
, vol.32
, Issue.11
, pp. 1491-1497
-
-
Poli, F.1
Plazzi, G.2
Di Dalmazi, G.3
|