Comparison of perirectal versus rectal Swabs for detection of asymptomatic carriers of toxigenic clostridium difficile

Journal of Clinical Microbiology

Volumn 51, Issue 10, 2013, Pages 3421-3422

  Rogers, David S ^a   Kundrapu, Sirisha ^a   Sunkesula, Venkata C K ^a   Donskey, Curtis J ^a  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIUM CARRIER; BACTERIUM COLONY; CLINICAL ARTICLE; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; HUMAN; INTERMETHOD COMPARISON; INTESTINE EXAMINATION; LONG TERM CARE; NONHUMAN; PERIRECTAL SWAB; PREDICTIVE VALUE; PRIORITY JOURNAL; RECTAL SWAB; SENSITIVITY AND SPECIFICITY; SPINAL CORD INJURY;

ANAL CANAL; BACTERIOLOGICAL TECHNIQUES; CARRIER STATE; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; FEMALE; HUMANS; MALE; PREDICTIVE VALUE OF TESTS; RECTUM; SENSITIVITY AND SPECIFICITY; SPECIMEN HANDLING;

EID: 84884754927     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.01418-13     Document Type: Article

References (12)

1. Riggs MM, Sethi AK, Zabarsky TF, Eckstein EC, Jump RL, Donskey CJ. 2007. Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents. Clin. Infect. Dis. 45:992-998. (Pubitemid 47580347)
2. Clabots CR, Johnson S, Olson MM, Peterson LR, Gerding DN. 1992. Acquisition of Clostridium difficile by hospitalized patients: evidence for colonized new admissions as a source of infection. J. Infect. Dis. 166:561-567.
3. Loo VG, Bourgault AM, Poirier L, Lamothe F, Michaud S, Turgeon N, Toye B, Beaudoin A, Frost EH, Gilca R, Brassard P, Dendukuri N, Béliveau C, Oughton M, Brukner I, Dascal A. 2011. Host and pathogen factors for Clostridium difficile infection and colonization. N. Engl. J. Med. 365:1693-1703.
4. Curry SR, Muto CA, Schlackman JL, Pasculle AW, Shutt KA, Marsh JW, Harrison LH. 23 July 2013. Use of MLVA genotyping to determine the role of asymptomatic carriers in C. difficile transmission. Clin. Infect. Dis. [Epub ahead of print.] doi:10.1093/cid/cit475.
5. Freifeld AG, Bow EJ, Sepkowitz KA, Boeckh MJ, Ito JI, Mullen CA, Raad II, Rolston KV, Young JA, Wingard JR, Infectious Diseases Society of America. 2011. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Diseases Society of America. Clin. Infect. Dis. 52:e56-e93.
6. Weinstein JW, Tallapragada S, Farrel P, Dembry L. 1996. Comparison of rectal and perirectal swabs for detection of colonization with vancomycin-resistant enterococci. J. Clin. Microbiol. 34:210-212. (Pubitemid 126506928)
7. Lautenbach E, Harris AD, Perencevich EN, Nachamkin I, Tolomeo P, Metlay JP. 2005. Test characteristics of perirectal and rectal swab compared to stool sample for detection of fluoroquinolone-resistant Escherichia coli in the gastrointestinal tract. Antimicrob. Agents Chemother. 49:798-800. (Pubitemid 40175701)
8. Kundrapu S, Sunkesula VC, Jury LA, Sethi AK, Donskey CJ. 2012. Utility of perirectal swab specimens for diagnosis of Clostridium difficile infection. Clin. Infect. Dis. 55:1527-1530.
9. Dumford DM, III, Nerandzic MM, Chang S, Richmond MA, Donskey CJ. 2011. Epidemiology of Clostridium difficile and vancomycin-resistance Enterococcus colonization in patients on a spinal cord injury unit. J. Spinal Cord. Med. 34:22-27.
10. Nerandzic MM, Donskey CJ. 2009. Effective and reduced-cost modified selective medium for isolation of Clostridium difficile. J. Clin. Microbiol. 47:397-400.
11. Villano SA, Seiberling M, Tatarowicz W, Monnot-Chase E, Gerding DN. 2012. Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects. Antimicrob. Agents Chemother. 56:5224-5229.
12. Cohen SH, Gerding DN, Johnson S, Kelly CP, Loo VG, McDonald LC, Pepin J, Wilcox MH. 2010. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect. Control Hosp. Epidemiol. 31:431-455.