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Volumn 73, Issue 18, 2013, Pages 5730-5741

Rapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 1; CELL ANTIGEN; CLARA CELL ANTIGEN 10; FIBROBLAST GROWTH FACTOR 9; FIBROBLAST GROWTH FACTOR RECEPTOR 3; SURFACTANT PROTEIN C; UNCLASSIFIED DRUG;

EID: 84884752845     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0495     Document Type: Article
Times cited : (50)

References (53)
  • 2
    • 84866410479 scopus 로고    scopus 로고
    • Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
    • Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell 2012;150:1107-20.
    • (2012) Cell , vol.150 , pp. 1107-1120
    • Imielinski, M.1    Berger, A.H.2    Hammerman, P.S.3    Hernandez, B.4    Pugh, T.J.5    Hodis, E.6
  • 3
    • 84866434919 scopus 로고    scopus 로고
    • Genomic landscape of non-small cell lung cancer in smokers and never-smokers
    • Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, et al. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell 2012;150:1121-34.
    • (2012) Cell , vol.150 , pp. 1121-1134
    • Govindan, R.1    Ding, L.2    Griffith, M.3    Subramanian, J.4    Dees, N.D.5    Kanchi, K.L.6
  • 4
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5    Brannigan, B.W.6
  • 6
    • 39649116928 scopus 로고    scopus 로고
    • EGFR tyrosine kinase inhibitors in lung cancer: An evolving story
    • Sequist LV, Lynch TJ. EGFR tyrosine kinase inhibitors in lung cancer: an evolving story. Annu Rev Med 2008;59:429-42.
    • (2008) Annu Rev Med , vol.59 , pp. 429-442
    • Sequist, L.V.1    Lynch, T.J.2
  • 7
    • 80052437758 scopus 로고    scopus 로고
    • New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer
    • Oxnard GR, Arcila ME, Chmielecki J, Ladanyi M, Miller VA, Pao W. New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer. Clin Cancer Res 2011;17:5530-7.
    • (2011) Clin Cancer Res , vol.17 , pp. 5530-5537
    • Oxnard, G.R.1    Arcila, M.E.2    Chmielecki, J.3    Ladanyi, M.4    Miller, V.A.5    Pao, W.6
  • 8
    • 84857407325 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling in non-smallcell lung cancer
    • Semrad TJ, Mack PC. Fibroblast growth factor signaling in non-smallcell lung cancer. Clin Lung Cancer 2012;13:90-5.
    • (2012) Clin Lung Cancer , vol.13 , pp. 90-95
    • Semrad, T.J.1    Mack, P.C.2
  • 9
    • 75149170979 scopus 로고    scopus 로고
    • Fibroblast growth factor signalling: From development to cancer
    • Turner N, Grose R. Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer 2010;10:116-29.
    • (2010) Nat Rev Cancer , vol.10 , pp. 116-129
    • Turner, N.1    Grose, R.2
  • 10
    • 1842735367 scopus 로고    scopus 로고
    • Influence of basic fibroblast growth factor on the proliferation of non-small cell lung cancer cell lines
    • Kuhn H, Kopff C, Konrad J, Riedel A, Gessner C, Wirtz H. Influence of basic fibroblast growth factor on the proliferation of non-small cell lung cancer cell lines. Lung Cancer 2004;44:167-74.
    • (2004) Lung Cancer , vol.44 , pp. 167-174
    • Kuhn, H.1    Kopff, C.2    Konrad, J.3    Riedel, A.4    Gessner, C.5    Wirtz, H.6
  • 11
    • 67651165437 scopus 로고    scopus 로고
    • Prognostic impact of fibroblast growth factor 2 in non-small cell lung cancer: Coexpression with VEGFR-3 and PDGF-B predicts poor survival
    • Donnem T, Al-Shibli K, Al-Saad S, Busund LT, Bremnes RM. Prognostic impact of fibroblast growth factor 2 in non-small cell lung cancer: coexpression with VEGFR-3 and PDGF-B predicts poor survival. J Thorac Oncol 2009;4:578-85.
    • (2009) J Thorac Oncol , vol.4 , pp. 578-585
    • Donnem, T.1    Al-Shibli, K.2    Al-Saad, S.3    Busund, L.T.4    Bremnes, R.M.5
  • 12
    • 1542719213 scopus 로고    scopus 로고
    • Basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) levels, as prognostic indicators in NSCLC
    • Iwasaki A, Kuwahara M, Yoshinaga Y, Shirakusa T. Basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) levels, as prognostic indicators in NSCLC. Eur J Cardiothorac Surg 2004;25:443-8.
    • (2004) Eur J Cardiothorac Surg , vol.25 , pp. 443-448
    • Iwasaki, A.1    Kuwahara, M.2    Yoshinaga, Y.3    Shirakusa, T.4
  • 13
    • 48749092646 scopus 로고    scopus 로고
    • Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms
    • Li ZG, Mathew P, Yang J, Starbuck MW, Zurita AJ, Liu J, et al. Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. J Clin Invest 2008;118:2697-710.
    • (2008) J Clin Invest , vol.118 , pp. 2697-2710
    • Li, Z.G.1    Mathew, P.2    Yang, J.3    Starbuck, M.W.4    Zurita, A.J.5    Liu, J.6
  • 14
    • 58849122812 scopus 로고    scopus 로고
    • Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells
    • Marek L, Ware KE, Fritzsche A, Hercule P, Helton WR, Smith JE, et al. Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells. Mol Pharmacol 2009;75: 196-207.
    • (2009) Mol Pharmacol , vol.75 , pp. 196-207
    • Marek, L.1    Ware, K.E.2    Fritzsche, A.3    Hercule, P.4    Helton, W.R.5    Smith, J.E.6
  • 15
    • 40549124915 scopus 로고    scopus 로고
    • Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with membranous beta-catenin
    • Abdel-Rahman WM, Kalinina J, Shoman S, Eissa S, Ollikainen M, Elomaa O, et al. Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with membranous beta-catenin. Hum Mutat 2008;29:390-7.
    • (2008) Hum Mutat , vol.29 , pp. 390-397
    • Abdel-Rahman, W.M.1    Kalinina, J.2    Shoman, S.3    Eissa, S.4    Ollikainen, M.5    Elomaa, O.6
  • 16
    • 32944462571 scopus 로고    scopus 로고
    • Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas
    • Hendrix ND, Wu R, Kuick R, Schwartz DR, Fearon ER, Cho KR. Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas. Cancer Res 2006;66:1354-62.
    • (2006) Cancer Res , vol.66 , pp. 1354-1362
    • Hendrix, N.D.1    Wu, R.2    Kuick, R.3    Schwartz, D.R.4    Fearon, E.R.5    Cho, K.R.6
  • 17
    • 84855382989 scopus 로고    scopus 로고
    • MicroRNA-99b acts as a tumor suppressor in non-small cell lung cancer by directly targeting fibroblast growth factor receptor
    • Kang J, Lee SY, Kim YJ, Park JY, Kwon SJ, Na MJ, et al. MicroRNA-99b acts as a tumor suppressor in non-small cell lung cancer by directly targeting fibroblast growth factor receptor. Exp Ther Med 2012;3: 149-53.
    • (2012) Exp Ther Med , vol.3 , pp. 149-153
    • Kang, J.1    Lee, S.Y.2    Kim, Y.J.3    Park, J.Y.4    Kwon, S.J.5    Na, M.J.6
  • 19
    • 78650451788 scopus 로고    scopus 로고
    • Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
    • Weiss J, Sos ML, Seidel D, Peifer M, Zander T, Heuckmann JM, et al. Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med 2010;2:62ra93.
    • (2010) Sci Transl Med , vol.2
    • Weiss, J.1    Sos, M.L.2    Seidel, D.3    Peifer, M.4    Zander, T.5    Heuckmann, J.M.6
  • 20
    • 79955675804 scopus 로고    scopus 로고
    • Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression
    • Ware KE, Marshall ME, Heasley LR, Marek L, Hinz TK, Hercule P, et al. Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression. PLoS ONE 2010;5:e14117.
    • (2010) PLoS ONE , vol.5
    • Ware, K.E.1    Marshall, M.E.2    Heasley, L.R.3    Marek, L.4    Hinz, T.K.5    Hercule, P.6
  • 21
    • 67650065531 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor activation and overexpression upregulated fibroblast growth factor-9 in human lung adenocarcinomas
    • Wang CK, Chang H, Chen PH, Chang JT, Kuo YC, Ko JL, et al. Aryl hydrocarbon receptor activation and overexpression upregulated fibroblast growth factor-9 in human lung adenocarcinomas. Int J Cancer 2009;125:807-15.
    • (2009) Int J Cancer , vol.125 , pp. 807-815
    • Wang, C.K.1    Chang, H.2    Chen, P.H.3    Chang, J.T.4    Kuo, Y.C.5    Ko, J.L.6
  • 22
    • 24944565402 scopus 로고    scopus 로고
    • Induction of fibroblast growth factor-9 and interleukin-1{alpha} gene expression by motorcycle exhaust particulate extracts and benzo(a) pyrene in human lung adenocarcinoma cells
    • Ueng TH, Hung CC, Kuo ML, Chan PK, Hu SH, Yang PC, et al. Induction of fibroblast growth factor-9 and interleukin-1{alpha} gene expression by motorcycle exhaust particulate extracts and benzo(a) pyrene in human lung adenocarcinoma cells. Toxicol Sci 2005;87: 483-96.
    • (2005) Toxicol Sci , vol.87 , pp. 483-496
    • Ueng, T.H.1    Hung, C.C.2    Kuo, M.L.3    Chan, P.K.4    Hu, S.H.5    Yang, P.C.6
  • 23
    • 77956230476 scopus 로고    scopus 로고
    • Potential roles of fibroblast growth factor-9 in the benzo(a)pyrene- induced invasion in vitro and the metastasis of human lung adenocarcinoma
    • Ueng TH, Chang YL, Tsai YY, Su JL, Chan PK, Shih JY, et al. Potential roles of fibroblast growth factor-9 in the benzo(a)pyrene-induced invasion in vitro and the metastasis of human lung adenocarcinoma. Arch Toxicol 2010;84:651-60.
    • (2010) Arch Toxicol , vol.84 , pp. 651-660
    • Ueng, T.H.1    Chang, Y.L.2    Tsai, Y.Y.3    Su, J.L.4    Chan, P.K.5    Shih, J.Y.6
  • 24
    • 0036677403 scopus 로고    scopus 로고
    • Early restriction of peripheral and proximal cell lineages during formation of the lung
    • Perl AK, Wert SE, Nagy A, Lobe CG, Whitsett JA. Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc Natl Acad Sci U S A 2002;99:10482-7.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10482-10487
    • Perl, A.K.1    Wert, S.E.2    Nagy, A.3    Lobe, C.G.4    Whitsett, J.A.5
  • 25
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999;21:70-1.
    • (1999) Nat Genet , vol.21 , pp. 70-71
    • Soriano, P.1
  • 26
    • 33646705916 scopus 로고    scopus 로고
    • FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains
    • White AC, Xu J, Yin Y, Smith C, Schmid G, Ornitz DM. FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains. Development 2006;133:1507-17.
    • (2006) Development , vol.133 , pp. 1507-1517
    • White, A.C.1    Xu, J.2    Yin, Y.3    Smith, C.4    Schmid, G.5    Ornitz, D.M.6
  • 27
    • 0036008331 scopus 로고    scopus 로고
    • Conditional gene expression in the respiratory epithelium of the mouse
    • Perl AK, Tichelaar JW, Whitsett JA. Conditional gene expression in the respiratory epithelium of the mouse. Transgenic Res 2002;11:21-9.
    • (2002) Transgenic Res , vol.11 , pp. 21-29
    • Perl, A.K.1    Tichelaar, J.W.2    Whitsett, J.A.3
  • 28
    • 0029928791 scopus 로고    scopus 로고
    • Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
    • Colvin JS, Bohne BA, Harding GW, McEwen DG, Ornitz DM. Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat Genet 1996;12:390-7.
    • (1996) Nat Genet , vol.12 , pp. 390-397
    • Colvin, J.S.1    Bohne, B.A.2    Harding, G.W.3    McEwen, D.G.4    Ornitz, D.M.5
  • 29
    • 65249098332 scopus 로고    scopus 로고
    • Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics
    • Teisanu RM, Lagasse E, Whitesides JF, Stripp BR. Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics. Stem Cells 2009;27:612-22.
    • (2009) Stem Cells , vol.27 , pp. 612-622
    • Teisanu, R.M.1    Lagasse, E.2    Whitesides, J.F.3    Stripp, B.R.4
  • 30
    • 3042689941 scopus 로고    scopus 로고
    • A simple, robust hardware device for passive or active respiratory gating in MRI and MRS experiments
    • Garbow JR, Dugas JP, Song SK, Conradi MS. A simple, robust hardware device for passive or active respiratory gating in MRI and MRS experiments. Concepts Magn Reson 2004;21B:40-8.
    • (2004) Concepts Magn Reson , vol.21 B , pp. 40-48
    • Garbow, J.R.1    Dugas, J.P.2    Song, S.K.3    Conradi, M.S.4
  • 31
    • 0034697322 scopus 로고    scopus 로고
    • Conditional expression of fibroblast growth factor-7 in the developing and mature lung
    • Tichelaar JW, Lu W, Whitsett JK. Conditional expression of fibroblast growth factor-7 in the developing and mature lung. J Biol Chem 2000;275:11858-64.
    • (2000) J Biol Chem , vol.275 , pp. 11858-11864
    • Tichelaar, J.W.1    Lu, W.2    Whitsett, J.K.3
  • 33
    • 46049108335 scopus 로고    scopus 로고
    • An FGF-WNT gene regulatory network controls lung mesenchyme development
    • Yin Y, White AC, Huh SH, Hilton MJ, Kanazawa H, Long F, et al. An FGF-WNT gene regulatory network controls lung mesenchyme development. Dev Biol 2008;319:426-36.
    • (2008) Dev Biol , vol.319 , pp. 426-436
    • Yin, Y.1    White, A.C.2    Huh, S.H.3    Hilton, M.J.4    Kanazawa, H.5    Long, F.6
  • 34
    • 84866036117 scopus 로고    scopus 로고
    • E-cadherin as a predictive marker of brain metastasis in non-small-cell lung cancer, and its regulation by pioglitazone in a preclinical model
    • Yoo JY, Yang SH, Lee JE, Cho DG, Kim HK, Kim SH, et al. E-cadherin as a predictive marker of brain metastasis in non-small-cell lung cancer, and its regulation by pioglitazone in a preclinical model. J Neurooncol 2012;109:219-27.
    • (2012) J Neurooncol , vol.109 , pp. 219-227
    • Yoo, J.Y.1    Yang, S.H.2    Lee, J.E.3    Cho, D.G.4    Kim, H.K.5    Kim, S.H.6
  • 37
    • 20444397431 scopus 로고    scopus 로고
    • Identification of bronchioalveolar stem cells in normal lung and lung cancer
    • Kim CF, Jackson EL, Woolfenden AE, Lawrence S, Babar I, Vogel S, et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 2005;121:823-35.
    • (2005) Cell , vol.121 , pp. 823-835
    • Kim, C.F.1    Jackson, E.L.2    Woolfenden, A.E.3    Lawrence, S.4    Babar, I.5    Vogel, S.6
  • 38
    • 66049083441 scopus 로고    scopus 로고
    • The role of Scgb1a1 Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium
    • Rawlins EL, Okubo T, Xue Y, Brass DM, Auten RL, Hasegawa H, et al. The role of Scgb1a1 Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell 2009; 4:525-34.
    • (2009) Cell Stem Cell , vol.4 , pp. 525-534
    • Rawlins, E.L.1    Okubo, T.2    Xue, Y.3    Brass, D.M.4    Auten, R.L.5    Hasegawa, H.6
  • 39
    • 76549126430 scopus 로고    scopus 로고
    • Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung
    • McQualter JL, Yuen K, Williams B, Bertoncello I. Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung. Proc Natl Acad Sci U S A 2010;107:1414-9.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 1414-1419
    • McQualter, J.L.1    Yuen, K.2    Williams, B.3    Bertoncello, I.4
  • 40
    • 84859476198 scopus 로고    scopus 로고
    • Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma
    • Xu X, Rock JR, Lu Y, Futtner C,Schwab B, Guinney J, et al. Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma. Proc Natl Acad Sci U S A 2012;109:4910-5.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 4910-4915
    • Xu, X.1    Rock, J.R.2    Lu, Y.3    Futtner, C.4    Schwab, B.5    Guinney, J.6
  • 41
    • 67650792487 scopus 로고    scopus 로고
    • Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung
    • Abler LL, Mansour SL, Sun X. Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung. Dev Dyn 2009;238:1999-2013.
    • (2009) Dev Dyn , vol.238 , pp. 1999-2013
    • Abler, L.L.1    Mansour, S.L.2    Sun, X.3
  • 42
    • 0031700905 scopus 로고    scopus 로고
    • FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
    • Weinstein M, Xu X, Ohyama K, Deng CX. FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 1998;125:3615-23.
    • (1998) Development , vol.125 , pp. 3615-3623
    • Weinstein, M.1    Xu, X.2    Ohyama, K.3    Deng, C.X.4
  • 43
    • 55749088215 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: Therapeutic implications and synergism with epidermal growth factor receptor inhibition
    • Fischer H, Taylor N, Allerstorfer S, Grusch M, Sonvilla G, Holzmann K, et al. Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition. Mol Cancer Ther 2008;7:3408-19.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3408-3419
    • Fischer, H.1    Taylor, N.2    Allerstorfer, S.3    Grusch, M.4    Sonvilla, G.5    Holzmann, K.6
  • 45
    • 34948850396 scopus 로고    scopus 로고
    • Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
    • Yanagi S, Kishimoto H, Kawahara K, Sasaki T, Sasaki M, Nishio M, et al. Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. J Clin Invest 2007;117: 2929-40.
    • (2007) J Clin Invest , vol.117 , pp. 2929-2940
    • Yanagi, S.1    Kishimoto, H.2    Kawahara, K.3    Sasaki, T.4    Sasaki, M.5    Nishio, M.6
  • 46
    • 34249807348 scopus 로고    scopus 로고
    • P38alpha MAPkinase is essential in lung stem and progenitor cell proliferation and differentiation
    • Ventura JJ, Tenbaum S, Perdiguero E, Huth M, Guerra C, Barbacid M, et al. p38alpha MAPkinase is essential in lung stem and progenitor cell proliferation and differentiation. Nat Genet 2007;39:750-8.
    • (2007) Nat Genet , vol.39 , pp. 750-758
    • Ventura, J.J.1    Tenbaum, S.2    Perdiguero, E.3    Huth, M.4    Guerra, C.5    Barbacid, M.6
  • 47
    • 34447544650 scopus 로고    scopus 로고
    • Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype
    • Besson A, Hwang HC, Cicero S, Donovan SL, Gurian-West M, Johnson D, et al. Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype. Genes Dev 2007;21:1731-46.
    • (2007) Genes Dev , vol.21 , pp. 1731-1746
    • Besson, A.1    Hwang, H.C.2    Cicero, S.3    Donovan, S.L.4    Gurian-West, M.5    Johnson, D.6
  • 48
    • 46249127489 scopus 로고    scopus 로고
    • A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration
    • Zhang Y, Goss AM, Cohen ED, Kadzik R, Lepore JJ, Muthukumaraswamy K, et al. A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration. Nat Genet 2008;40:862-70.
    • (2008) Nat Genet , vol.40 , pp. 862-870
    • Zhang, Y.1    Goss, A.M.2    Cohen, E.D.3    Kadzik, R.4    Lepore, J.J.5    Muthukumaraswamy, K.6
  • 50
    • 0037417438 scopus 로고    scopus 로고
    • Immunohistochemical analysis of Clara cell secretory protein expression in a transgenic model of mouse lung carcinogenesis
    • Hicks SM, Vassallo JD, Dieter MZ, Lewis CL, Whiteley LO, Fix AS, et al. Immunohistochemical analysis of Clara cell secretory protein expression in a transgenic model of mouse lung carcinogenesis. Toxicology 2003;187:217-28.
    • (2003) Toxicology , vol.187 , pp. 217-228
    • Hicks, S.M.1    Vassallo, J.D.2    Dieter, M.Z.3    Lewis, C.L.4    Whiteley, L.O.5    Fix, A.S.6
  • 51
    • 0035111259 scopus 로고    scopus 로고
    • Molecular cloning and developmental expression of rat fibroblast growth factor receptor 3
    • Claus P, Grothe C. Molecular cloning and developmental expression of rat fibroblast growth factor receptor 3. Histochem Cell Biol 2001; 115:147-55.
    • (2001) Histochem Cell Biol , vol.115 , pp. 147-155
    • Claus, P.1    Grothe, C.2
  • 52
    • 78650875209 scopus 로고    scopus 로고
    • Small molecule FGF receptor inhibitors block FGFRdependent urothelial carcinoma growth in vitro and in vivo
    • Lamont FR, Tomlinson DC, Cooper PA, Shnyder SD, Chester JD, Knowles M.A. Small molecule FGF receptor inhibitors block FGFRdependent urothelial carcinoma growth in vitro and in vivo. Br J Cancer 2011;104:75-82.
    • (2011) Br J Cancer , vol.104 , pp. 75-82
    • Lamont, F.R.1    Tomlinson, D.C.2    Cooper, P.A.3    Shnyder, S.D.4    Chester, J.D.5    Knowles, M.A.6
  • 53
    • 33749337828 scopus 로고    scopus 로고
    • The use of targeted mouse models for preclinical testing of novel cancer therapeutics
    • Olive KP, Tuveson DA. The use of targeted mouse models for preclinical testing of novel cancer therapeutics. Clin Cancer Res 2006;12: 5277-87.
    • (2006) Clin Cancer Res , vol.12 , pp. 5277-5287
    • Olive, K.P.1    Tuveson, D.A.2


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