The role of CC10 in pulmonary carcinogenesis: From a marker to tumor suppression

Annals of the New York Academy of Sciences

Volumn 923, Issue , 2000, Pages 249-267

  Ilona Linnoila, R ^a   Szabo, Eva ^a   Demayo, Francesco ^b   Witschi, Hanspeter ^c   Sabourin, Carol ^d   Malkinson, Al ^e  

^a NATIONAL CANCER INSTITUTE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLARA CELL PROTEIN;

ANCHORAGE INDEPENDENT GROWTH; BRONCHUS MUCOSA; CANCER INHIBITION; CONFERENCE PAPER; DISEASE MARKER; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; STEM CELL;

BRONCHUS; CRICETINAE; NICOTIANA TABACUM;

EID: 0034502526     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb05534.x     Document Type: Conference Paper

References (60)

1. Cancer Facts and Figures 2000
2. Pathology of non-small cell lung cancer: New diagnostic approaches
3. Rising incidence of bronchioloalveolar lung carcinoma and its unique clinicopathological features
4. Human urinary protein 1: Evidence for identity with Clara cell protein and occurrence in respiratory tract and urogenital tract secretions
5. Uteroglobin: A novel cytokine?
6. Ultrastructure of the nonciliated bronchiolar epithelial (Clara) cell of mammalian lung. III. A study of man with comparison of 15 mammalian species
7. Expression of surfactant associated protein-A and Clara cell 10 kilodalton mRNA in neoplastic and non-neoplastic human lung tissue as detected by in situ hybridization
8. Role of the Clara cell in renewal of the bronchiolar epithelium
9. The differentiation capacity of Clara cells isolated from the lungs of rabbits
10. Clara cell granules of peripheral lung cancers
11. The spectrum and significance of bronchioloalveolar carcinomas
12. Peripheral airway cell marker expression in non-small cell lung carcinoma
13. Frequent expression of bronchioloalveolar cell markers in pulmonary large cell and adenocarcinomas by immunohistochemistry
14. Overexpression of CC10 modifies neoplastic potential in lung cancer cells
15. Peripheral airway cell differentiation in human lung cancer cell lines
16. Detection of peripheral airway cell differentiation in human lung cancer lines by RNA-RNA in situ hybridization with ultrastructural correlation
17. "Field cancerization" in oral stratified squamous epithelium: Clinical implications of multicentric origin
18. Genetic evidence for independent origin of multiple preneoplastic and neoplastic lung lesions
19. Clara cell protein in serum and bronchoalveolar lavage
20. Clara cell 10 kD protein mRNA in normal and atypical regions of human respiratory epithelium
21. Goblet and Clara cells of human distal airways: Evidence for smoking induced changes in their numbers
22. The brochiolar epithelium in cigarette smokers
23. Serum and BAL Clara cell 10 kDa protein (CC10) levels and CC10 positive bronchiolar cells are decreased in smokers
24. Morphogenesis of alveolar bronchiolization
25. The pathology of bronchiolization of alveoli: Progressive changes during human lung carcinogenesis
26. Frequent alterations of chromosome 3p in peripheral lung during pulmonary carcinogenesis in man
27. Tumors as caricatures of the process of tissue renewal: Prospects for therapy by directing differentiation
28. Suppression of retinoic acid receptor-β in premalignant oral lesions and its up-regulation by isotretinoin
29. Phenotype and genotype of advanced premalignant head and neck lesions after chemopreventative therapy
30. Loss of transformed phenotype in cancer cells by overexpression of the uteroglobin gene
31. Recombinant human uteroglobin inhibits the in vitro invasiveness of human metastatic prostate tumor cells and the release of arachidonic acid stimulated by fibroblast-conditioned medium
32. 1 integrin receptor in the proliferative response of quiescent human melanoma cells to fibronectin
33. 1 integrins during human melanoma cell invasion
34. Inhibited transformation of immortalized human bronchial epithelial cells by retinoic acid is linked to cyclin E down-regulation
35. Cyclin D1 overexpression vs. retinoblastoma inactivation: Implications for growth control evasion in non-small cell and small cell lung cancer
36. INK4a expression in resected non-small cell lung tumors
37. Schüller H.M.
38. Immunohistochemical demonstration of Clara cell antigen in lung tumors of bronchiolar origin induced by N-nitrosodiethylamine in Syrian golden hamsters
39. Histochemical characterization of non-neuroendocrine tumors and neuroendocrine cell hyperplasia induced in hamster lung by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone with or without hyperoxia
40. Clara cell antigen in normal and migratory dysplastic Clara cells, and bronchioalveolar carcinoma of Syrian hamsters induced by N-nitrosomethyl-n-heptylamine
41. Reduced expression of Clara cell secretory protein (CC10) during early lung carcinogenesis in a hamster model
42. Early changes during experimental lung carcinogenesis detected by laser capture microdissection and immunohistochemistry
43. K-ras and p-53 point mutations in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced hamster lung tumors
44. Premalignant changes involving neuroendocrine (NE) cells and Clara cell secretory protein (CC10) during tobacco-specific nitrosamine (NNK) induced lung carcinogenesis in mice
45. Transient increase of serum Clara cell protein (CC16) after exposure to smoke
46. Response of bronchiolar Clara cells induced by a domestic insecticide: Analysis of CC10 kDa protein content
47. Mouse bronchiolar cell carcinogenesis: Histologic characterization and expression of Clara cell antigen in lesions induced by N-nitrosobis-(2-chloroethyl) ureas
48. A transgenic mouse model for lung adenocarcinoma
49. Expression of SV40 T antigen under control of rabbit uteroglobin promoter in transgenic mice
50. Cyclin-dependent kinase inhibitor expression in pulmonary Clara cells transformed with SV40 large T antigen in transgenic mice
51. Role of SV40 T antigen binding to pRb and p53 in multistep transformation in vitro of human uroepithelial cells
52. An achaete-scute homologue essential for neuroendocrine differentiation in the lung
53. Constitutive achaete-scute homolog-1 (hASH1) promotes airway dysplasia and lung neuroendocrine tumors in transgenic mice
54. Impact of neuroendocrine differentiation in non-small cell lung cancer: The LCSG experience