Clinical significance of overexpressed cyclin-dependent kinase subunits 1 and 2 in esophageal carcinoma

Diseases of the Esophagus

Volumn 26, Issue 7, 2013, Pages 729-736

  Wang, J J ^a   Fang, Z X ^a   Ye, H M ^a   You, P ^a   Cai, M J ^a   Duan, H B ^a   Wang, F ^c   Zhang, Z Y ^b  

^a XIAMEN UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

Cks1; Cks2; Esophageal carcinoma; P27kip1

Indexed keywords

CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MESSENGER RNA;

ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; ESOPHAGUS CARCINOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

CKS1; CKS2; ESOPHAGEAL CARCINOMA; P27KIP1;

CARCINOMA; CARCINOMA, SQUAMOUS CELL; CARRIER PROTEINS; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ESOPHAGEAL NEOPLASMS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84884707161     PISSN: 11208694     EISSN: 14422050     Source Type: Journal    
DOI: 10.1111/dote.12013     Document Type: Article

References (26)

1. Richardson H E, Stueland C S, Thomas J, Russell P, Reed S I. Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe. Genes Dev 1990; 4: 1332-1344.
2. Hara T, Kamura T, Nakayama K, Oshikawa K, Hatakeyama S. Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway. J Biol Chem 2001; 276: 48937-48943.
3. Kamura T, Hara T, Matsumoto M etal. Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase. Nat Cell Biol 2004; 6: 1229-1235.
4. Lan Y, Zhang Y, Wang J, Lin C, Ittmann M M, Wang F. Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. Int J Cancer 2008; 123: 543-551.
5. Liu Z, Fu Q, Lv J, Wang F, Ding K. Prognostic implication of p27kip1, Skp2 and Cks1 expression in renal cell carcinoma: a tissue microarray study. J Exp Clin Cancer Res 2008; 27: 51-59.
6. Bhatt K V, Hu R, Spofford L S, Aplin A E. Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase associated protein 2-mediated degradation of p27kip1 in human melanoma cells. Oncogene 2007; 26: 1056-6.
7. Shapira M, Ben-Izhak O, Linn S, Futerman B, Minkov I, Hershko D D. The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma. Cancer 2005; 103: 1336-4.
8. Shen D Y, Fang Z X, You P etal. Clinical significance and expression of cyclin kinase subunits 1 and 2 in hepatocellular carcinoma. Liver Int 2010; 30 (1): 119-125.
9. Lan Y, Zhang Y, Wang J, Lin C, Ittmann M M, Wang F. Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. Int J Cancer 2008; 123 (3): 543-551.
10. Kang M A, Kim J T, Kim J H etal. Upregulation of the cycline kinase subunit CKS2 increases cell proliferation rate in gastric cancer. J Cancer Res Clin Oncol 2009; 135 (6): 761-769.
11. Wong Y F, Cheung T H, Tsao G S etal. Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray. Int J Cancer 2006; 118 (10): 2461-2469.
12. Lyng H, Brøvig R S, Svendsrud D H etal. Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer. BMC Genomics 2006; 7: 268-283.
13. Kawakami K, Enokida H, Tachiwada T etal. Identification of differentially expressed genes in human bladder cancer though genome-wide gene expression profiling. Oncol Rep 2006; 16 (3): 521-531.
14. Wiese A H, Auer J, Lassmann S etal. Identification of gene signatures for invasive colorectal tumor cells. Cancer Detect Prev 2007; 31 (4): 282-295.
15. Lin H M, Chatterjee A, Lin Y H etal. Genome wide expression profiling identifies genes associated with colorectal liver metastasis. Oncol Rep 2007; 17 (6): 1541-1549.
16. Zhou Z G, Gao X S, Qiao X Y, Zhang P. Literature analysis of radiotherapy for esophageal cancer in China. Chin J Cancer 2010; 29: 873-881.
17. Rice T W, Rusch V W, Apperson-Hansen C etal. Worldwide esophageal cancer collaboration. Dis Esophagus 2009; 22: 1-8.
18. Enzinger P C, Mayer R J. Esophageal cancer. N Engl J Med 2003; 349: 2241-2252.
19. Chen L Q, Hu C Y, Ghadirian P, Duranceau A. Early detection of esophageal squamous cell carcinoma and its effects on therapy: an overview. Dis Esophagus 1999; 12 (3): 161-167.
20. Nabeya Y, Ochiai T, Matsubara H etal. Neoadjuvant chemoradiotherapy followed by esophagectomy for initially resectable squamous cell carcinoma of the esophagus with multiple lymph node metastasis. Dis Esophagus 2005; 18 (6): 388-397.
21. Sobin L H, Gospodarowicz M K, Wittekind C, (eds). TNM classification of malignant tumors, 7th edn. Oxford: Wiley-Blackwell, 2010.
22. Ganoth D, Bornstein G, Ko T K etal. The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27. Nat Cell Biol 2001; 3: 321-324.
23. Spruck C, Strohmaier H, Watson M etal. A CDK-independent function of mammalian Cks1: targeting of SCFSkp2 to the CDK inhibitor p27. Mol Cell 2001; 7: 639-650.
24. Sitry D, Seeliger M A, Ko T K etal. Three different binding sites of Cks1 are required for p27-ubiquitin ligation. J Biol Chem 2002; 277: 42233-42240.
25. Pagano M, Tam S W, Theodoras A M etal. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995; 269: 682-685.
26. Wolthuis R L, Clay-Farrace W, van Zon M etal. Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A. Mol Cell 2008; 30: 290-302.