A systematic review of factors associated with the deferral of donors failing to meet low haemoglobin thresholds

Transfusion Medicine

Volumn 23, Issue 5, 2013, Pages 309-320

  Smith, Graham A ^a,b   Fisher, Sheila A ^b   Dorée, Carolyn ^b   Roberts, David J ^b,c  

^a ROYAL FREE LONDON NHS FOUNDATION TRUST   (United Kingdom)

^b NHS BLOOD AND TRANSPLANT   (United Kingdom)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Anaemia; Blood donation; Blood donor; Deferral; Haemoglobin; Systematic review

Indexed keywords

HEMOGLOBIN;

AGING; ARTICLE; BLOOD DONOR; ENVIRONMENTAL TEMPERATURE; HEMOGLOBIN BLOOD LEVEL; HUMAN; META ANALYSIS; RACE DIFFERENCE; SEX DIFFERENCE; SYSTEMATIC REVIEW; UNDERWEIGHT; DONOR SELECTION; FEMALE; MALE; MEDLINE; PROCEDURES; STANDARDS;

BLOOD DONORS; DONOR SELECTION; FEMALE; HEMOGLOBINS; HUMANS; MALE; MEDLINE;

EID: 84884705121     PISSN: 09587578     EISSN: 13653148     Source Type: Journal    
DOI: 10.1111/tme.12046     Document Type: Article

References (46)

1. Agnihotri, N. (2010) Whole blood donor deferral analysis at a center in Western India. Asian Journal of Transfusion Science, 4, 116-122.
2. Arslan, O. (2007) Whole blood donor deferral rate and characteristics of the Turkish population. Transfusion Medicine, 17, 379-383.
3. ASH: action on smoking and health (2007) Tobacco: Global Trends. URL http://www.ash.org.uk/files/documents/ASH_562.pdf (Accessed 30/10/12).
4. Baart, A.M., de Kort, W.L., Moons, K.G. & Vergouwe, Y. (2011) Prediction of low haemoglobin levels in whole blood donors. Vox Sanguinis, 100, 204-211.
5. Baart, A.M., de, Kort, W.L., Atsma, F., Moons, K.G. & Vergouwe, Y. (2012) Development and validation of a prediction model for low hemoglobin deferral in a large cohort of whole blood donors. Transfusion, 52, 2559-2569.
6. Beutler, E. & Waalen, J. (2006) The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration? Blood, 107, 1747-1750.
7. Bhasin, S., Woodhouse, L., Casaburi, R. et al. (2001) Testosterone dose-response relationships in healthy young men. American Journal of Physiology, Endocrinology and Metabolism, 281, E1172-E1181.
8. Bianco, C., Brittenham, G., Gilcher, R.O. et al. (2002) Maintaining iron balance in women blood donors of childbearing age: summary of a workshop. Transfusion, 42, 798-805.
9. Council of Europe. (2010) Guide to the Preparation, Use and Quality Assurance of Blood Components. Council of Europe Publishing, Strasbourg.
10. Custer, B., Johnson, E.S., Sullivan, S.D., Hazlet, T.K., Ramsey, S.D., Hirschler, N.V., Murphy, E.L. & Busch, M.P. (2004) Quantifying losses to the donated blood supply due to donor deferral and miscollection. Transfusion, 44, 1417-1426.
11. Custer, B., Chinn, A., Hirschler, N.V., Busch, M.P. & Murphy, E.L. (2007) The consequences of temporary deferral on future whole blood donation. Transfusion, 47, 1514-1523.
12. Custer, B., Schlumpf, K., Simon, T.L., Spencer, B.R., Wright, D.J., Wilkinson, S.L. & NHLBI Retrovirus Epidemiology Donor Study, I (2012) Demographics of successful, unsuccessful and deferral visits at six blood centers over a 4-year period. Transfusion, 52, 712-721.
13. Di Lorenzo Oliveira, C., Loureiro, F., de Bastos, M.R., Proietti, F.A. & Carneiro-Proietti, A.B. (2009) Blood donor deferral in Minas Gerais State, Brazil: blood centers as sentinels of urban population health. Transfusion, 49, 851-857.
14. Eder, A., Goldman, M., Rossmann, S., Waxman, D. & Bianco, C. (2009) Selection criteria to protect the blood donor in North America and Europe: past (dogma), present (evidence), and future (hemovigilance). Transfusion Medicine Reviews, 23, 205-220.
15. European Vegetarian Society (2012) How Many Veggies...? URL http://www.euroveg.eu/lang/en/info/howmany.php (Accessed 30/10/12).
16. Finch, C.A., Cook, J.D., Labbe, R.F. & Culala, M. (1977) Effect of blood donation on iron stores as evaluated by serum ferritin. Blood, 50, 441-447.
17. Gandhi, M.J., Duffy, K., Benike, M., Jenkins, S. & Stubbs, J.R. (2012) Effect of increasing hemoglobin cutoff in male donors and increasing interdonation interval in whole blood donors at a hospital-based blood donor center. Transfusion, 52, 1880-1888.
18. Girish, C.J., Chandrashekhar, T.N., Ramesh, B.K. & Kantikar, S.M. (2012) Pre-donation deferral of whole blood donors in district transfusion centre. Journal of Clinical and Diagnostic Research, 6, 47-50.
19. Goncalez, T.T., Sabino, E.C., Schlumpf, K.S. et al. (2013) Analysis of donor deferral at three blood centers in Brazil. Transfusion, 53, 531-538.
20. Gulen, H., Tuzun, F., Ayhan, Y., Erbay, A., Ozturk, E., Inan, S. & Vergin, C. (2006) The evaluation of blood donor deferral causes. Pediatric Hematology and Oncology, 23, 91-94.
21. Guralnik, J.M., Eisenstaedt, R.S., Ferrucci, L., Klein, H.G. & Woodman, R.C. (2004) Prevalence of anemia in persons 65years and older in the United States: evidence for a high rate of unexplained anemia. Blood, 104, 2263-2268.
22. Guralnik, J.M., Ershler, W.B., Schrier, S.L. & Picozzi, V.J. (2005) Anemia in the elderly: a public health crisis in hematology. Hematology/the Education Program of the American Society of Hematology. American Society of Hematology. Education Program, 2005, 528-532.
23. Harteveld, C.L. & Higgs, D.R. (2010) Alpha-thalassaemia. Orphanet Journal of Rare Diseases, 5, 13.
24. Hillgrove, T., Moore, V., Doherty, K. & Ryan, P. (2011) The impact of temporary deferral due to low hemoglobin: future return, time to return, and frequency of subsequent donation. Transfusion, 51, 539-547.
25. Hoekstra, T., Veldhuizen, I., van, Noord, P.A. & de Kort, W.L. (2007) Seasonal influences on hemoglobin levels and deferral rates in whole-blood and plasma donors. Transfusion, 47, 895-900.
26. Kouao, M.D., Dembele, B., N'Goran, L.K., Konate, S., Bloch, E., Murphy, E.L. & Lefrere, J.J. (2012) Reasons for blood donation deferral in sub-Saharan Africa: experience in Ivory Coast. Transfusion, 52, 1602-1606.
27. Lau, P., Hansen, M. & Sererat, M. (1988) Influence of climate on donor deferrals. Transfusion, 28, 559-562.
28. Lim, J.C., Tien, S.L. & Ong, Y.W. (1993) Main causes of pre-donation deferral of prospective blood donors in the Singapore Blood Transfusion Service. Annals of the Academy of Medicine, 22, 326-331.
29. Mast, A.E., Foster, T.M., Pinder, H.L. et al. (2008) Behavioral, biochemical, and genetic analysis of iron metabolism in high-intensity blood donors. Transfusion, 48, 2197-2204.
30. Mast, A.E., Schlumpf, K.S., Wright, D.J., Custer, B., Spencer, B., Murphy, E.L., Simon, T.L. & Nhlbi Retrovirus Epidemiology Donor Study, I (2010) Demographic correlates of low hemoglobin deferral among prospective whole blood donors. Transfusion, 50, 1794-1802.
31. NHSBT (2010) Annual Report. URL http://www.nhsbt.nhs.uk/annualreview/progress-09-10/blood-components (Accessed 18/2/11).
32. Nilsson-Ehle, H., Jagenburg, R., Landahl, S., Svanborg, A. & Westin, J. (1988) Haematological abnormalities and reference intervals in the elderly. A cross-sectional comparative study of three urban Swedish population samples aged 70, 75 and 81years. Acta Medica Scandinavica, 224, 595-604.
33. Oliveira, C.D., Martins, G., Custer, B., Proietti, F.A., Carneiro-Proietti, A.B. & Cesar, C.C. (2011) Hierarchical analysis of anaemia deferral in blood donor candidates: the individual in the population perspective. Transfusion Medicine, 21, 371-377.
34. Page, E.A., Coppock, J.E. & Harrison, J.F. (2010) Study of iron stores in regular plateletpheresis donors. Transfusion Medicine, 20, 22-29.
35. Review Manager (RevMan). (2011) [computer program]. The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen.
36. Sebok, M.A., Notari, E.P., Chambers, L.A., Benjamin, R.J. & Eder, A.F. (2007) Seasonal temperature variation and the rate of donor deferral for low hematocrit in the American Red Cross. Transfusion, 47, 890-894.
37. Shaz, B.H., James, A.B., Hillyer, K.L., Schreiber, G.B. & Hillyer, C.D. (2010) Demographic variations in blood donor deferrals in a major metropolitan area. Transfusion, 50, 881-887.
38. Sundar, P., Sangeetha, S.K., Seema, D.M., Marimuthu, P. & Shivanna, N. (2010) Pre-donation deferral of blood donors in South Indian set-up: An analysis. Asian Journal of Transfusion Science, 4, 112-115.
39. Tondon, R., Pandey, P. & Chaudhry, R. (2008) A 3-year analysis of plateletpheresis donor deferral pattern in a tertiary health care institute: assessing the current donor selection criteria in Indian scenario. Journal of Clinical Apheresis, 23, 123-128.
40. United Kingdom Blood Transfusion Services. (2005) Guidelines for the Blood Transfusion Services in the UK. The Stationery Office Limited, London.
41. US Food and Drug Administration. (2008) Recommendations of the Advisory Committee on Blood Safety and Availability. URL http://www.hhs.gov/ash/bloodsafety/advisorycommittee/recommendations/resdec08.pdf (Accessed 30/11/12)
42. Watanabe, G.I. (1958) Climatic effect on the packed red-cell volume. British Journal of Haematology, 4, 108-112.
43. Wilkinson, J.L. (1982) Haemoglobin levels in blood donor volunteers-a 20-year survey. Irish Medical Journal, 75, 115.
44. Yadav, Y., & Kumar, S. (2006) The food habits of a nation. The Hindu (online), 14 August 2006. URL http://www.hindu.com/2006/08/14/stories/2006081403771200.htm (Accessed 23/12/11).
45. Zanella, A., Milani, S., Silvani, C. et al. (1989) Monitoringhemoglobin and iron status in blood donors to prevent iron deficiency. Bibliotheca Nutritio et Dieta, 131-143.
46. Ziemann, M., Steppat, D., Brockmann, C., Washington, G., Kirchner, H. & Schlenke, P. (2006) Selection of whole-blood donors for hemoglobin testing by use of historical hemoglobin values. Transfusion, 46, 2176-2183.