Generation of protection against Francisella novicida in mice depends on the pathogenicity protein PdpA, but not PdpC or PdpD

Microbes and Infection

Volumn 15, Issue 12, 2013, Pages 816-827

  Chou, Alicia Y ^a,c   Kennett, Nikki J ^a   Nix, Eli B ^b,d   Schmerk, Crystal L ^b,e   Nano, Francis E ^b   Elkins, Karen L ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b UNIVERSITY OF VICTORIA   (Canada)

^c Reagan Udall Foundation   (United States)

^d NORTHERN ONTARIO SCHOOL OF MEDICINE   (Canada)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Francisella; Mice; Pathogenicity island; Protective immunity; T lymphocytes

Indexed keywords

BACTERIAL PROTEIN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12P40; NITRIC OXIDE; PROTEIN PDPA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BALB CBY MOUSE; C57BL 6 MOUSE; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELETION MUTANT; ENZYME LINKED IMMUNOSORBENT ASSAY; FRANCISELLA NOVICIDA; FRANCISELLA TULARENSIS; GENE DELETION; GENE MUTATION; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE INFECTION; IMMUNE SYSTEM; IMMUNIZATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PATHOGENICITY ISLAND; PDPA GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; STRAIN DIFFERENCE; T LYMPHOCYTE; TULAREMIA;

BACTERIA (MICROORGANISMS); FRANCISELLA; FRANCISELLA TULARENSIS; FRANCISELLA TULARENSIS SUBSP. NOVICIDA; MUS;

FRANCISELLA; MICE; PATHOGENICITY ISLAND; PROTECTIVE IMMUNITY; T LYMPHOCYTES;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; FEMALE; FRANCISELLA; GENE DELETION; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; SURVIVAL ANALYSIS; TULAREMIA; VIRULENCE FACTORS;

EID: 84884700968     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2013.07.005     Document Type: Article

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