What is the rate of methicillin-resistant staphylococcus aureus and gram-negative infections in open fractures?

Clinical Orthopaedics and Related Research

Volumn 471, Issue 10, 2013, Pages 3135-3140

  Chen, Antonia F ^a   Schreiber, Verena M ^a   Washington, Wesley ^a   Rao, Nalini ^a   Evans, Andrew R ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AEROMONAS HYDROPHILA; BACTERIUM CULTURE; CANDIDA; CLINICAL EVALUATION; CLINICAL FEATURE; CLOSTRIDIUM; COAGULASE NEGATIVE STAPHYLOCOCCUS; COHORT ANALYSIS; CONFERENCE PAPER; CONTROLLED STUDY; ENTEROBACTER AEROGENES; ENTEROBACTER CLOACAE; ENTEROCOCCUS FAECALIS; FEMALE; FOLLOW UP; GRAM NEGATIVE INFECTION; HUMAN; INCIDENCE; INFECTION RATE; KLEBSIELLA PNEUMONIAE; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MORGANELLA MORGANII; OPEN FRACTURE; PRIORITY JOURNAL; PSEUDOMONAS; RETROSPECTIVE STUDY; SERRATIA MARCESCENS;

EID: 84884700336     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1007/s11999-013-2855-4     Document Type: Conference Paper

References (23)

1. Awad SS, Elhabash SI, Lee L, Farrow B, Berger DH. Increasing incidence of methicillin-resistant Staphylococcus aureus skin and soft-tissue infections: reconsideration of empiric antimicrobial therapy. Am J Surg. 2007;194:606-610.
2. Calfee DP. Methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci, and other Gram-positives in healthcare. Curr Opin Infect Dis. 2012;25:385-394.
3. Carsenti-Etesse H, Doyon F, Desplaces N, Gagey O, Tancrede C, Pradier C, Dunais B, Dellamonica P. Epidemiology of bacterial infection during management of open leg fractures. Eur J Clin Microbiol Infect Dis. 1999;18:315-323.
4. Dellinger EP, Caplan ES, Weaver LD, Wertz MJ, Droppert BM, Hoyt N, Brumback R, Burgess A, Poka A, Benirschke SK, et al. Duration of preventive antibiotic administration for open extremity fractures. Arch Surg. 1988;123:333-339.
5. Dellinger EP, Miller SD, Wertz MJ, Grypma M, Droppert B, Anderson PA. Risk of infection after open fracture of the arm or leg. Arch Surg. 1988;123:1320-1327.
6. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control. 1988;16:128-140.
7. Glass GE, Barrett SP, Sanderson F, Pearse MF, Nanchahal J. The microbiological basis for a revised antibiotic regimen in high-energy tibial fractures: preventing deep infections by nosocomial organisms. J Plast Reconstr Aesthet Surg. 2011;64:375-380.
8. Gustilo R, Merkow R, Templeman D. Current concepts review: the management of open fractures. J Bone Joint Surg Am. 1990;72:299-304.
9. Gustilo RB, Anderson JT. Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. J Bone Joint Surg Am. 1976;58:453-458.
10. Gustilo RB, Gruninger RP, Davis T. Classification of type III (severe) open fractures relative to treatment and results. Orthopedics. 1987;10:1781-1788.
11. Gustilo RB, Mendoza RM, Williams DN. Problems in the management of type III (severe) open fractures: a new classification of type III open fractures. J Trauma. 1984;24:742-746.
12. Johnson EN, Burns TC, Hayda RA, Hospenthal DR, Murray CK. Infectious complications of open type III tibial fractures among combat casualties. Clin Infect Dis. 2007;45:409-415.
13. Johnson KD, Johnston DW. Orthopedic experience with methicillin-resistant Staphylococcus aureus during a hospital epidemic. Clin Orthop Relat Res. 1986;212:281-288.
14. Jorgenson MR, DePestel DD, Carver PL. Ceftaroline fosamil: a novel broad-spectrum cephalosporin with activity against methicillin-resistant Staphylococcus aureus. Ann Pharmacother. 2011;45:1384-1398.
15. Mackenzie EJ, Rivara FP, Jurkovich GJ, Nathens AB, Egleston BL, Salkever DS, Frey KP, Scharfstein DO. The impact of trauma-center care on functional outcomes following major lower-limb trauma. J Bone Joint Surg Am. 2008;90:101-109.
16. Ong CT, Choon DS, Cabrera NP, Maffulli N. The treatment of open tibial fractures and of tibial non-union with a novel external fixator. Injury. 2002;33:829-834.
17. Patzakis MJ, Harvey JP Jr, Ivler D. The role of antibiotics in the management of open fractures. J Bone Joint Surg Am. 1974;56:532-541.
18. Patzakis MJ, Wilkins J, Moore TM. Considerations in reducing the infection rate in open tibial fractures. Clin Orthop Relat Res. 1983;178:36-41.
19. Poon H, Chang MH, Fung HB. Ceftaroline fosamil: a cephalosporin with activity against methicillin-resistant Staphylococcus aureus. Clin Ther. 2012;34:743-765.
20. Ray GT, Suaya JA, Baxter R. Trends and characteristics of culture-confirmed Staphylococcus aureus infections in a large US integrated health care organization. J Clin Microbiol. 2012;50:1950-1957.
21. Rittmann WW, Schibli M, Matter P, Allgower M. Open fractures. Long-term results in 200 consecutive cases. Clin Orthop Relat Res. 1979;138:132-140.
22. Saveli CC, Belknap RW, Morgan SJ, Price CS. The role of prophylactic antibiotics in open fractures in an era of community-acquired methicillin-resistant Staphylococcus aureus. Orthopedics. 2011;34:611-616; quiz 617.
23. Yokoyama K, Itoman M, Shindo M, Kai H. Contributing factors influencing type III open tibial fractures. J Trauma. 1995;38:788-793.