-
1
-
-
62449321780
-
Unsupervised analysis of transcriptomic profiles reveals six glioma subtypes
-
Li A, Walling J, Ahn S, Kotliarov Y, Su Q, et al. (2009) Unsupervised analysis of transcriptomic profiles reveals six glioma subtypes. Cancer Res 69: 2091-2099.
-
(2009)
Cancer Res
, vol.69
, pp. 2091-2099
-
-
Li, A.1
Walling, J.2
Ahn, S.3
Kotliarov, Y.4
Su, Q.5
-
2
-
-
20144376240
-
Gene expression profiling and genetic markers in glioblastoma survival
-
Rich JN, Hans C, Jones B, Iversen ES, McLendon RE, et al. (2005) Gene expression profiling and genetic markers in glioblastoma survival. Cancer Res 65: 4051-4058.
-
(2005)
Cancer Res
, vol.65
, pp. 4051-4058
-
-
Rich, J.N.1
Hans, C.2
Jones, B.3
Iversen, E.S.4
McLendon, R.E.5
-
3
-
-
33645825183
-
Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer
-
Ein-Dor L, Zuk O, Domany E, (2006) Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer. Proc Natl Acad Sci U S A 103: 5923-5928.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5923-5928
-
-
Ein-Dor, L.1
Zuk, O.2
Domany, E.3
-
4
-
-
67650882239
-
A systems biology-based gene expression classifier of glioblastoma predicts survival with solid tumors
-
Zhang J, Liu B, Jiang X, Zhao H, Fan M, et al. (2009) A systems biology-based gene expression classifier of glioblastoma predicts survival with solid tumors. PLoS One 4: e6274.
-
(2009)
PLoS One
, vol.4
-
-
Zhang, J.1
Liu, B.2
Jiang, X.3
Zhao, H.4
Fan, M.5
-
5
-
-
79952423666
-
Subnetwork state functions define dysregulated subnetworks in cancer
-
Chowdhury SA, Nibbe RK, Chance MR, Koyuturk M, (2011) Subnetwork state functions define dysregulated subnetworks in cancer. J Comput Biol 18: 263-281.
-
(2011)
J Comput Biol
, vol.18
, pp. 263-281
-
-
Chowdhury, S.A.1
Nibbe, R.K.2
Chance, M.R.3
Koyuturk, M.4
-
6
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
The Cancer Genome Atlas
-
The Cancer Genome Atlas (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
7
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, et al. (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17: 98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
-
8
-
-
67650436675
-
Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age
-
Lee Y, Scheck AC, Cloughesy TF, Lai A, Dong J, et al. (2008) Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age. BMC Med Genomics 1: 52.
-
(2008)
BMC Med Genomics
, vol.1
, pp. 52
-
-
Lee, Y.1
Scheck, A.C.2
Cloughesy, T.F.3
Lai, A.4
Dong, J.5
-
9
-
-
20144389740
-
Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma
-
Nigro JM, Misra A, Zhang L, Smirnov I, Colman H, et al. (2005) Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res 65: 1678-1686.
-
(2005)
Cancer Res
, vol.65
, pp. 1678-1686
-
-
Nigro, J.M.1
Misra, A.2
Zhang, L.3
Smirnov, I.4
Colman, H.5
-
10
-
-
33845807801
-
Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities
-
Maher EA, Brennan C, Wen PY, Durso L, Ligon KL, et al. (2006) Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities. Cancer Res 66: 11502-11513.
-
(2006)
Cancer Res
, vol.66
, pp. 11502-11513
-
-
Maher, E.A.1
Brennan, C.2
Wen, P.Y.3
Durso, L.4
Ligon, K.L.5
-
11
-
-
1642453725
-
Age-dependent prognostic effects of genetic alterations in glioblastoma
-
Batchelor TT, Betensky RA, Esposito JM, Pham LD, Dorfman MV, et al. (2004) Age-dependent prognostic effects of genetic alterations in glioblastoma. Clin Cancer Res 10: 228-233.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 228-233
-
-
Batchelor, T.T.1
Betensky, R.A.2
Esposito, J.M.3
Pham, L.D.4
Dorfman, M.V.5
-
12
-
-
80055090025
-
Most random gene expression signatures are significantly associated with breast cancer outcome
-
Venet D, Dumont JE, Detours V, (2011) Most random gene expression signatures are significantly associated with breast cancer outcome. PLoS Comput Biol 7: e1002240.
-
(2011)
PLoS Comput Biol
, vol.7
-
-
Venet, D.1
Dumont, J.E.2
Detours, V.3
-
13
-
-
0037381008
-
Gene expression-based classification of malignant gliomas correlates better with survival than histological classification
-
Nutt CL, Mani DR, Betensky RA, Tamayo P, Cairncross JG, et al. (2003) Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res 63: 1602-1607.
-
(2003)
Cancer Res
, vol.63
, pp. 1602-1607
-
-
Nutt, C.L.1
Mani, D.R.2
Betensky, R.A.3
Tamayo, P.4
Cairncross, J.G.5
-
14
-
-
4644313275
-
Gene expression profiling of gliomas strongly predicts survival
-
Freije WA, Castro-Vargas FE, Fang Z, Horvath S, Cloughesy T, et al. (2004) Gene expression profiling of gliomas strongly predicts survival. Cancer Res 64: 6503-6510.
-
(2004)
Cancer Res
, vol.64
, pp. 6503-6510
-
-
Freije, W.A.1
Castro-Vargas, F.E.2
Fang, Z.3
Horvath, S.4
Cloughesy, T.5
-
15
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, et al. (2006) Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9: 157-173.
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
-
16
-
-
70849122697
-
Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
-
Brennan C, Momota H, Hambardzumyan D, Ozawa T, Tandon A, et al. (2009) Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS One 4: e7752.
-
(2009)
PLoS One
, vol.4
-
-
Brennan, C.1
Momota, H.2
Hambardzumyan, D.3
Ozawa, T.4
Tandon, A.5
-
17
-
-
33847665105
-
Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas
-
Price ND, Trent J, El-Naggar AK, Cogdell D, Taylor E, et al. (2007) Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas. Proc Natl Acad Sci U S A 104: 3414-3419.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3414-3419
-
-
Price, N.D.1
Trent, J.2
El-Naggar, A.K.3
Cogdell, D.4
Taylor, E.5
-
18
-
-
35148837581
-
Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway-therapeutic perspectives in cancer
-
Tao Y, Pinzi V, Bourhis J, Deutsch E, (2007) Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway-therapeutic perspectives in cancer. Nat Clin Pract Oncol 4: 591-602.
-
(2007)
Nat Clin Pract Oncol
, vol.4
, pp. 591-602
-
-
Tao, Y.1
Pinzi, V.2
Bourhis, J.3
Deutsch, E.4
-
19
-
-
0036141447
-
Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling
-
Chakravarti A, Loeffler JS, Dyson NJ, (2002) Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res 62: 200-207.
-
(2002)
Cancer Res
, vol.62
, pp. 200-207
-
-
Chakravarti, A.1
Loeffler, J.S.2
Dyson, N.J.3
-
20
-
-
33947320145
-
Insulin-like growth factor type I biology and targeting in malignant gliomas
-
Trojan J, Cloix JF, Ardourel MY, Chatel M, Anthony DD, (2007) Insulin-like growth factor type I biology and targeting in malignant gliomas. Neuroscience 145: 795-811.
-
(2007)
Neuroscience
, vol.145
, pp. 795-811
-
-
Trojan, J.1
Cloix, J.F.2
Ardourel, M.Y.3
Chatel, M.4
Anthony, D.D.5
-
21
-
-
77951747892
-
Initial testing of a monoclonal antibody (IMC-A12) against IGF-1R by the Pediatric Preclinical Testing Program
-
Houghton PJ, Morton CL, Gorlick R, Kolb EA, Keir ST, et al. (2010) Initial testing of a monoclonal antibody (IMC-A12) against IGF-1R by the Pediatric Preclinical Testing Program. Pediatr Blood Cancer 54: 921-926.
-
(2010)
Pediatr Blood Cancer
, vol.54
, pp. 921-926
-
-
Houghton, P.J.1
Morton, C.L.2
Gorlick, R.3
Kolb, E.A.4
Keir, S.T.5
-
22
-
-
67651039919
-
A network model of a cooperative genetic landscape in brain tumors
-
Bredel M, Scholtens DM, Harsh GR, Bredel C, Chandler JP, et al. (2009) A network model of a cooperative genetic landscape in brain tumors. JAMA 302: 261-275.
-
(2009)
JAMA
, vol.302
, pp. 261-275
-
-
Bredel, M.1
Scholtens, D.M.2
Harsh, G.R.3
Bredel, C.4
Chandler, J.P.5
-
23
-
-
78649823233
-
Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes
-
Duncan CG, Killela PJ, Payne CA, Lampson B, Chen WC, et al. (2010) Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes. Oncotarget 1: 265-277.
-
(2010)
Oncotarget
, vol.1
, pp. 265-277
-
-
Duncan, C.G.1
Killela, P.J.2
Payne, C.A.3
Lampson, B.4
Chen, W.C.5
-
24
-
-
0037101955
-
Invasive behaviour of glioblastoma cell lines is associated with altered organisation of the cadherin-catenin adhesion system
-
Perego C, Vanoni C, Massari S, Raimondi A, Pola S, et al. (2002) Invasive behaviour of glioblastoma cell lines is associated with altered organisation of the cadherin-catenin adhesion system. J Cell Sci 115: 3331-3340.
-
(2002)
J Cell Sci
, vol.115
, pp. 3331-3340
-
-
Perego, C.1
Vanoni, C.2
Massari, S.3
Raimondi, A.4
Pola, S.5
-
25
-
-
79954626807
-
beta-catenin and Gli1 are prognostic markers in glioblastoma
-
Rossi M, Magnoni L, Miracco C, Mori E, Tosi P, et al. (2011) beta-catenin and Gli1 are prognostic markers in glioblastoma. Cancer Biol Ther 11: 753-761.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 753-761
-
-
Rossi, M.1
Magnoni, L.2
Miracco, C.3
Mori, E.4
Tosi, P.5
-
26
-
-
0031588345
-
Topoisomerase-I inhibitors for human malignant glioma: differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and beta-lapachone
-
Weller M, Winter S, Schmidt C, Esser P, Fontana A, et al. (1997) Topoisomerase-I inhibitors for human malignant glioma: differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and beta-lapachone. Int J Cancer 73: 707-714.
-
(1997)
Int J Cancer
, vol.73
, pp. 707-714
-
-
Weller, M.1
Winter, S.2
Schmidt, C.3
Esser, P.4
Fontana, A.5
-
27
-
-
39749119942
-
Next generation topoisomerase I inhibitors: Rationale and biomarker strategies
-
Teicher BA, (2008) Next generation topoisomerase I inhibitors: Rationale and biomarker strategies. Biochem Pharmacol 75: 1262-1271.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1262-1271
-
-
Teicher, B.A.1
-
28
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood LD, Parsons DW, Jones S, Lin J, Sjoblom T, et al. (2007) The genomic landscapes of human breast and colorectal cancers. Science 318: 1108-1113.
-
(2007)
Science
, vol.318
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
Lin, J.4
Sjoblom, T.5
-
29
-
-
78649642467
-
Protein abundances are more conserved than mRNA abundances across diverse taxa
-
Laurent JM, Vogel C, Kwon T, Craig SA, Boutz DR, et al. (2010) Protein abundances are more conserved than mRNA abundances across diverse taxa. Proteomics 10: 4209-4212.
-
(2010)
Proteomics
, vol.10
, pp. 4209-4212
-
-
Laurent, J.M.1
Vogel, C.2
Kwon, T.3
Craig, S.A.4
Boutz, D.R.5
-
30
-
-
72149133974
-
iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype
-
Rajcevic U, Petersen K, Knol JC, Loos M, Bougnaud S, et al. (2009) iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype. Mol Cell Proteomics 8: 2595-2612.
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 2595-2612
-
-
Rajcevic, U.1
Petersen, K.2
Knol, J.C.3
Loos, M.4
Bougnaud, S.5
-
31
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da W, Sherman BT, Lempicki RA, (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
32
-
-
47549114245
-
Expression of nuclear factor-kappaB in human astrocytomas: relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival
-
Korkolopoulou P, Levidou G, Saetta AA, El-Habr E, Eftichiadis C, et al. (2008) Expression of nuclear factor-kappaB in human astrocytomas: relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival. Hum Pathol 39: 1143-1152.
-
(2008)
Hum Pathol
, vol.39
, pp. 1143-1152
-
-
Korkolopoulou, P.1
Levidou, G.2
Saetta, A.A.3
El-Habr, E.4
Eftichiadis, C.5
-
33
-
-
79951844223
-
NFKBIA deletion in glioblastomas
-
Bredel M, Scholtens DM, Yadav AK, Alvarez AA, Renfrow JJ, et al. (2011) NFKBIA deletion in glioblastomas. N Engl J Med 364: 627-637.
-
(2011)
N Engl J Med
, vol.364
, pp. 627-637
-
-
Bredel, M.1
Scholtens, D.M.2
Yadav, A.K.3
Alvarez, A.A.4
Renfrow, J.J.5
-
34
-
-
39749200037
-
Association of mortalin (HSPA9) with liver cancer metastasis and prediction for early tumor recurrence
-
Yi X, Luk JM, Lee NP, Peng J, Leng X, et al. (2008) Association of mortalin (HSPA9) with liver cancer metastasis and prediction for early tumor recurrence. Mol Cell Proteomics 7: 315-325.
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 315-325
-
-
Yi, X.1
Luk, J.M.2
Lee, N.P.3
Peng, J.4
Leng, X.5
-
35
-
-
11144349225
-
Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival
-
Dundas SR, Lawrie LC, Rooney PH, Murray GI, (2005) Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival. J Pathol 205: 74-81.
-
(2005)
J Pathol
, vol.205
, pp. 74-81
-
-
Dundas, S.R.1
Lawrie, L.C.2
Rooney, P.H.3
Murray, G.I.4
-
36
-
-
0031586587
-
Elevated levels of mortalin expression in human brain tumors
-
Takano S, Wadhwa R, Yoshii Y, Nose T, Kaul SC, et al. (1997) Elevated levels of mortalin expression in human brain tumors. Exp Cell Res 237: 38-45.
-
(1997)
Exp Cell Res
, vol.237
, pp. 38-45
-
-
Takano, S.1
Wadhwa, R.2
Yoshii, Y.3
Nose, T.4
Kaul, S.C.5
-
37
-
-
13244262655
-
Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM)
-
Yin D, Zhou H, Kumagai T, Liu G, Ong JM, et al. (2005) Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM). Oncogene 24: 344-354.
-
(2005)
Oncogene
, vol.24
, pp. 344-354
-
-
Yin, D.1
Zhou, H.2
Kumagai, T.3
Liu, G.4
Ong, J.M.5
-
38
-
-
23044506681
-
The ubiquitin-proteasome pathway and its role in cancer
-
Mani A, Gelmann EP, (2005) The ubiquitin-proteasome pathway and its role in cancer. J Clin Oncol 23: 4776-4789.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4776-4789
-
-
Mani, A.1
Gelmann, E.P.2
-
39
-
-
77952473808
-
Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count
-
Okada Y, Kamatani Y, Takahashi A, Matsuda K, Hosono N, et al. (2010) Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count. Hum Mol Genet 19: 2079-2085.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 2079-2085
-
-
Okada, Y.1
Kamatani, Y.2
Takahashi, A.3
Matsuda, K.4
Hosono, N.5
-
40
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z, (2002) Inflammation and cancer. Nature 420: 860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
41
-
-
0033854841
-
Elastase expression by infiltrating neutrophils in gliomas
-
Iwatsuki K, Kumara E, Yoshimine T, Nakagawa H, Sato M, et al. (2000) Elastase expression by infiltrating neutrophils in gliomas. Neurol Res 22: 465-468.
-
(2000)
Neurol Res
, vol.22
, pp. 465-468
-
-
Iwatsuki, K.1
Kumara, E.2
Yoshimine, T.3
Nakagawa, H.4
Sato, M.5
-
42
-
-
78649990580
-
Osteopontin is up-regulated and associated with neutrophil and macrophage infiltration in glioblastoma
-
Atai NA, Bansal M, Lo C, Bosman J, Tigchelaar W, et al. (2010) Osteopontin is up-regulated and associated with neutrophil and macrophage infiltration in glioblastoma. Immunology 132: 39-48.
-
(2010)
Immunology
, vol.132
, pp. 39-48
-
-
Atai, N.A.1
Bansal, M.2
Lo, C.3
Bosman, J.4
Tigchelaar, W.5
-
43
-
-
75549085083
-
Human Protein Reference Database and Human Proteinpedia as discovery tools for systems biology
-
Prasad TSK, Kandasamy K, Pandey A, (2009) Human Protein Reference Database and Human Proteinpedia as discovery tools for systems biology. Methods Mol Biol 577: 67-79.
-
(2009)
Methods Mol Biol
, vol.577
, pp. 67-79
-
-
Prasad, T.S.K.1
Kandasamy, K.2
Pandey, A.3
-
44
-
-
84884682711
-
Colorectal Cancer and Its Molecular Subsystems: Construction, Interpretation, and Validation
-
In: Emmert-Streib F, Dehmer M, editors, Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA
-
Patel VN, Chance MR (2013) Colorectal Cancer and Its Molecular Subsystems: Construction, Interpretation, and Validation. In: Emmert-Streib F, Dehmer M, editors. Statistical Diagnostics for Cancer: Analyzing High-Dimensional Data. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA.
-
(2013)
Statistical Diagnostics for Cancer: Analyzing High-Dimensional Data
-
-
Patel, V.N.1
Chance, M.R.2
|