Circulating Liver-Specific miR-122 as a Novel Potential Biomarker for Diagnosis of Cholestatic Liver Injury

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Shifeng, Huang ^a   Danni, Wang ^a   Pu, Chen ^a   Ping, Yang ^a   Ju, Cao ^a   Liping, Zhang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BIOLOGICAL MARKER; GAMMA GLUTAMYLTRANSFERASE; MICRORNA 122; RNA; RNA U6; UNCLASSIFIED DRUG;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOANALYZER; BILE DUCT STONE; BILIARY TRACT SURGERY; BILIRUBIN BLOOD LEVEL; CHOLESTATIC LIVER INJURY; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; INJURY SEVERITY; LIVER INJURY; MALE; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; STEM LOOP REAL TIME REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BIOLOGICAL MARKERS; CHOLESTASIS; FEMALE; HUMANS; LIVER DISEASES; MICE; MICE, INBRED BALB C; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; ROC CURVE;

EID: 84884678063     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073133     Document Type: Article

References (29)

1. Eulalio A, Huntzinger E, Izaurralde E, (2008) Getting to the root of miRNA-mediated gene silencing. Cell 132: 9-14.
2. Carthew RW, Sontheimer EJ, (2009) Origins and mechanisms of miRNAs and siRNAs. Cell 136: 642-655.
3. Williams AE, (2008) Functional aspects of animal microRNAs. Cell Mol Life Sci 65: 545-562.
4. Mott JL, Kobayashi S, Bronk SF, Gores GJ, (2007) Mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 26: 6133-6140.
5. Kanda T, Ishibashi O, Kawahigashi Y, Mishima T, Kosuge T, et al. (2010) Identification of obstructive jaundice-related microRNAs in mouse liver. Hepatogastroenterology 57: 1013-1023.
6. Roderburg C, Urban GW, Bettermann K, Vucur M, Zimmermann H, et al. (2011) Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis. Hepatology 53: 209-218.
7. Huang J, Wang Y, Guo Y, Sun S, (2010) Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1. Hepatology 52: 60-70.
8. Huang Z, Huang D, Ni S, Peng Z, Sheng W, et al. (2010) Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer. Int J Cancer 127: 118-126.
9. Pineau P, Volinia S, McJunkin K, Marchio A, Battiston C, et al. (2010) miR-221 overexpression contributes to liver tumorigenesis. Proc Natl Acad Sci U S A 107: 264-269.
10. Tsujiura M, Ichikawa D, Komatsu S, Shiozaki A, Takeshita H, et al. (2010) Circulating microRNAs in plasma of patients with gastric cancers. Br J Cancer 102: 1174-1179.
11. Adachi T, Nakanishi M, Otsuka Y, Nishimura K, Hirokawa G, et al. (2010) Plasma microRNA 499 as a biomarker of acute myocardial infarction. Clin Chem 56: 1183-1185.
12. Wang GK, Zhu JQ, Zhang JT, Li Q, Li Y, et al. (2010) Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans. Eur Heart J 31: 659-666.
13. Wang K, Zhang S, Marzolf B, Troisch P, Brightman A, et al. (2009) Circulating microRNAs, potential biomarkers for drug-induced liver injury. PNAS 106: 4402-4407.
14. Zhang Y, Jia Y, Zheng R, Guo Y, Wang Y, et al. (2010) Plasma microRNA-122 as a biomarker for viral-, alcohol-, and chemical-related hepatic diseases. Clin Chem 56: 1830-1838.
15. Laterza OF, Lim L, Garrett-Engele PW, Vlasakova K, Muniappa N, et al. (2009) Plasma microRNAs as sensitive and specific biomarkers of tissue injury. Clin Chem 55: 1977-1983.
16. Chang J, Guo JT, Jiang D, Guo H, Taylor JM, et al. (2008) Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells. J Virol 82: 8215-8223.
17. Esau C, Davis S, Murray SF, Yu XX, Pandey SK, et al. (2006) miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab 3: 87-98.
18. Jangra RK, Yi Mk, Lemon SM, (2010) Regulation of Hepatitis C Virus Translation and Infectious Virus Production by the MicroRNA miR-122. J Virol 84: 6615-6625.
19. Sarasin-Filipowicz M, Krol J, Markiewicz I, Heim MH, Filipowicz W, (2009) Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nat Med 15: 31-33.
20. Bai SM, Nasser MW, Wang B, Hsu SH, Datta J, et al. (2009) MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J Biol Chem 284: 32015-32027.
21. Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, et al. (2010) Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327: 198-201.
22. Jiang JX, Mikami K, Shah VH, Torok NJ, (2008) Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphos-phatase-dependent mechanism. Hepatology 48: 1497-1505.
23. Lebovitz HE, Kreider M, Freed MI, (2002) Evaluation of liver function in type 2 diabetic patients during clinical trials: evidence that rosiglitazone does not cause hepatic dysfunction. Diabetes Care 25: 815-21.
24. Qin X, Li J, Cui Y, Liu Z, Zhao Z, et al. (2012) Effect of folic acid intervention on ALT concentration in hypertensives without known hepatic disease: a randomized, double-blind, controlled trial. Eur J Clin Nutr 66: 541-8.
25. Dufour DR, Lott JA, Nolte FS, Gretch DR, Koff RS, et al. (2000) Diagnosis and monitoring of hepatic injury. II. Recommendations for use of laboratory tests in screening diagnosis and monitoring. Clin Chem 46: 2050-68.
26. Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, et al. (2002) Identification of tissue-specific microRNAs from mouse. Curr Biol 12: 735-739.
27. Girard M, Jacquemin E, Munnich A, Lyonnet S, Henrion-Caude A, (2008) miR-122, a paradigm for the role of microRNAs in the liver. J Hepatol 48: 648-656.
28. Cheung O, Puri P, Eicken C, Contos MJ, Mirshahi F, et al. (2008) Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression. Hepatology 48: 1810-1820.
29. McDonald JS, Milosevic D, Reddi HV, Grebe SK, Algeciras-Schimnich A, (2011) Analysis of circulating microRNA: preanalytical and analytical challenges. Clin Chem 57: 833-840.