Novel effects of edaravone on human brain microvascular endothelial cells revealed by a proteomic approach

Brain Research

Volumn 1534, Issue , 2013, Pages 87-94

  Onodera, Hidetaka ^a,b   Arito, Mitsumi ^a   Sato, Toshiyuki ^a   Ito, Hidemichi ^b   Hashimoto, Takuo ^b   Tanaka, Yuichiro ^b   Kurokawa, Manae S ^a   Okamoto, Kazuki ^a   Suematsu, Naoya ^a   Kato, Tomohiro ^a  

^a ST MARIANNA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Blood brain barrier; Edaravone; Endothelium; Pharmacology

Indexed keywords

ACTIN; ALPHA GALACTOSIDASE; CALCIUM BINDING PROTEIN; CALCIUM BINDING PROTEIN 39LIK; ELONGATION FACTOR 2; ELONGATION FACTOR TU; F ACTIN; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GUANINE NUCLEOTIDE BINDING PROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; LACTIC ACID; MONOCYTE CHEMOTACTIC PROTEIN 1; NORPHENAZONE; PHENYLALANINE TRANSFER RNA LIGASE; PROTEIN; PROTEIN TYROSINE PHOSPHATASE; PYRUVATE KINASE; PYRUVIC ACID; UNCLASSIFIED DRUG; VIMENTIN;

ARTICLE; BRAIN; CELL MEMBRANE PERMEABILITY; CELL SIZE; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSKELETON; DOWN REGULATION; DRUG EFFECT; DRUG METABOLISM; FLUORESCENCE MICROSCOPY; HELA CELL; HUMAN; HUMAN BRAIN MICROVASCULAR ENDOTHELIAL CELL; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; LIPID PEROXIDATION; MICROVASCULAR ENDOTHELIAL CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; TIGHT JUNCTION; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

BLOOD-BRAIN BARRIER; EDARAVONE; ENDOTHELIUM; PHARMACOLOGY;

ANTIPYRINE; BRAIN; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HELA CELLS; HUMANS; LACTIC ACID; MICROVESSELS; PROTEOMICS; TIGHT JUNCTIONS;

EID: 84884671611     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.08.019     Document Type: Article

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