Analysis of peptides secreted from cultured mouse brain tissue

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1834, Issue 11, 2013, Pages 2408-2417

  Gelman, Julia S ^a   Dasgupta, Sayani ^a   Berezniuk, Iryna ^a   Fricker, Lloyd D ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Bioactive peptide; Neuropeptide; Peptidomics

Indexed keywords

CANNABINOID 1 RECEPTOR AGONIST; CELL PROTEIN; PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; BRAIN SLICE; BRAIN TISSUE; CELL COMMUNICATION; CYTOSOL; FEMALE; MALE; MOUSE; NONHUMAN; POSTMORTEM CHANGE; PRIORITY JOURNAL; SECRETORY PATHWAY;

4-TRIMETHYLAMMONIUMBUTYRATE; 4-TRIMETHYLAMMONIUMBUTYRYL-N-HYDROXYSUCCINIMIDE; ACSF; ARTIFICIAL CEREBROSPINAL FLUID; BIOACTIVE PEPTIDE; DIMETHYL SULFOXIDE; DMSO; LC/MS; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY; M/Z; MASS CHARGE RATIO; MS/MS; NEUROPEPTIDE; PEPTIDOMICS; TANDEM MASS SPECTROMETRY; TMAB; TMAB-NHS;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; BRAIN CHEMISTRY; FEMALE; MALE; MICE; MOLECULAR SEQUENCE DATA; NEUROPEPTIDES; PROTEOMICS; SECRETORY PATHWAY; TISSUE CULTURE TECHNIQUES;

EID: 84884669441     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2013.01.043     Document Type: Article

References (67)

1. L.D. Fricker Neuropeptides and Other Bioactive Peptides 2012 Morgan & Claypool Life Sciences Charleston, S.C.
2. F.L. Strand Neuropeptides: general characteristics and neuropharmaceutical potential in treating CNS disorders Prog. Drug Res. 61 2003 1 37 (Pubitemid 37187401)
3. M. Svensson, K. Skold, P. Svenningsson, and P.E. Andren Peptidomics-based discovery of novel neuropeptides J. Proteome Res. 2 2003 213 219 (Pubitemid 37099058)
4. M. Svensson, K. Skold, A. Nilsson, M. Falth, K. Nydahl, P. Svenningsson, and P.E. Andren Neuropeptidomics: MS applied to the discovery of novel peptides from the brain Anal. Chem. 79 2007 15 21
5. N.G. Hatcher, N. Atkins Jr., S.P. Annangudi, A.J. Forbes, N.L. Kelleher, M.U. Gillette, and J.V. Sweedler Mass spectrometry-based discovery of circadian peptides Proc. Natl. Acad. Sci. U. S. A. 105 2008 12527 12532
6. L. Li, and J.V. Sweedler Peptides in the brain: mass spectrometry-based measurement approaches and challenges Annu. Rev. Anal. Chem. 1 2008 451 483
7. A.B. Hummon, A. Amare, and J.V. Sweedler Discovering new invertebrate neuropeptides using mass spectrometry Mass Spectrom. Rev. 25 2006 77 98
8. K. Sasaki, N. Takahashi, M. Satoh, M. Yamasaki, and N. Minamino A peptidomics strategy for discovering endogenous bioactive peptides J. Proteome Res. 9 2010 5047 5052
9. N. Minamino, J. Tanaka, H. Kuwahara, T. Kihara, Y. Satomi, M. Matsubae, and T. Takao Determination of endogenous peptides in the porcine brain: possible construction of peptidome, a fact database for endogenous peptides J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 792 2003 33 48 (Pubitemid 36773799)
10. L.D. Fricker Analysis of mouse brain peptides using mass spectrometry-based peptidomics: implications for novel functions ranging from non-classical neuropeptides to microproteins Mol. Biosyst. 6 2010 1355 1365
11. L.D. Fricker, J. Lim, H. Pan, and F.Y. Che Peptidomics: Identification and quantification of endogenous peptides in neuroendocrine tissues Mass Spectrom. Rev. 25 2006 327 344
12. L.D. Fricker, A.A. McKinzie, J. Sun, E. Curran, Y. Qian, L. Yan, S.D. Patterson, P.L. Courchesne, B. Richards, N. Levin, N. Mzhavia, L.A. Devi, and J. Douglass Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing J. Neurosci. 20 2000 639 648 (Pubitemid 30225566)
13. D.A. Berti, C. Morano, L.C. Russo, L.M. Castro, F.M. Cunha, X. Zhang, J. Sironi, C.F. Klitzke, E.S. Ferro, and L.D. Fricker Analysis of intracellular substrates and products of thimet oligopeptidase (EC 3.4.24.15) in human embryonic kidney 293 cells J. Biol. Chem. 284 2009 14105 14116
14. F.M. Cunha, D.A. Berti, Z.S. Ferreira, C.F. Klitzke, R.P. Markus, and E.S. Ferro Intracellular peptides as natural regulators of cell signaling J. Biol. Chem. 283 2008 24448 24459
15. J.S. Gelman, J. Sironi, L.M. Castro, E.S. Ferro, and L.D. Fricker Peptidomic analysis of human cell lines J. Proteome Res. 10 2011 1583 1592
16. D.A. Berti, L.C. Russo, L.M. Castro, L. Cruz, F.C. Gozzo, J.C. Heimann, F.B. Lima, A.C. Oliveira, S. Andreotti, P.O. Prada, A.S. Heimann, and E.S. Ferro Identification of intracellular peptides in rat adipose tissue: insights into insulin resistance Proteomics 12 2012 2668 2681
17. L.C. Russo, A.F. Asega, L.M. Castro, P.D. Negraes, L. Cruz, F.C. Gozzo, H. Ulrich, A.C.M. Camargo, V. Rioli, and E.S. Ferro Natural intracellular peptides can modulate the interactions of mouse brain proteins and thimet oligopeptidase with 14-3-3 epsilon and calmodulin Proteomics 12 2012 2641 2655
18. A.S. Heimann, I. Gomes, C.S. Dale, R.L. Pagano, A. Gupta, L.L. de Souza, A.D. Luchessi, L.M. Castro, R. Giorgi, V. Rioli, E.S. Ferro, and L.A. Devi Hemopressin is an inverse agonist of CB1 cannabinoid receptors Proc. Natl. Acad. Sci. U. S. A. 104 2007 20588 20593
19. I. Gomes, J.S. Grushko, U. Golebiewska, S. Hoogendoorn, A. Gupta, A.S. Heimann, E.S. Ferro, S. Scarlata, L.D. Fricker, and L.A. Devi Novel endogenous peptide agonists of cannabinoid receptors FASEB J. 23 2009 3020 3029
20. J.S. Gelman, and L.D. Fricker Hemopressin and other bioactive peptides from cytosolic proteins: are these non-classical neuropeptides? AAPS J. 12 2010 279 289
21. G. Huyer, A. Kistler, F.J. Nouvet, C.M. George, M.L. Boyle, and S. Michaelis Saccharomyces cerevisiae a-factor mutants reveal residues critical for processing, activity, and export Eukaryot. Cell 5 2006 1560 1570 (Pubitemid 44423652)
22. W. Nickel The unconventional secretory machinery of fibroblast growth factor 2 Traffic 12 2011 799 805
23. A.L. Goldstein, E. Hannappel, and H.K. Kleinman Thymosin beta(4): actin-sequestering protein moonlights to repair injured tissues Trends Mol. Med. 11 2005 421 429 (Pubitemid 41254045)
24. N. Ueki, K. Someya, Y. Matsuo, K. Wakamatsu, and H. Mukai Cryptides: functional cryptic peptides hidden in protein structures Biopolymers 88 2007 190 198 (Pubitemid 46657985)
25. W. Nickel, and M. Seedorf Unconventional mechanisms of protein transport to the cell surface of eukaryotic cells Annu. Rev. Cell Dev. Biol. 24 2008 287 308
26. F.Y. Che, X. Zhang, I. Berezniuk, M. Callaway, J. Lim, and L.D. Fricker Optimization of neuropeptide extraction from the mouse hypothalamus J. Proteome Res. 6 2007 4667 4676
27. F.Y. Che, J. Lim, R. Biswas, H. Pan, and L.D. Fricker Quantitative neuropeptidomics of microwave-irradiated mouse brain and pituitary Mol. Cell. Proteomics 4 2005 1391 1405 (Pubitemid 41448725)
28. K. Skold, M. Svensson, M. Norrman, B. Sjogren, P. Svenningsson, and P.E. Andren The significance of biochemical and molecular sample integrity in brain proteomics and peptidomics: stathmin 2-20 and peptides as sample quality indicators Proteomics 7 2007 4445 4456
29. C. Morano, X. Zhang, and L.D. Fricker Multiple isotopic labels for quantitative mass spectrometry Anal. Chem. 80 2008 9298 9309
30. J.S. Gelman, J.H. Wardman, V.B. Bhat, F.C. Gozzo, and L.D. Fricker Quantitative peptidomics to measure neuropeptide levels in animal models relevant to psychiatric disorders Methods Mol. Biol. 829 2012 487 503
31. J. Wardman, and L.D. Fricker Quantitative peptidomics of mice lacking peptide-processing enzymes Methods Mol. Biol. 768 2011 307 323
32. L.D. Fricker, J.S. Gelman, L.M. Castro, F.C. Gozzo, and E.S. Ferro Peptidomic analysis of HEK293T cells: effect of the proteasome inhibitor epoxomicin on intracellular peptides J. Proteome Res. 11 2012 1981 1990
33. P.J. Lyons, and L.D. Fricker Peptidomic approaches to study proteolytic activity Current Protocols in Protein Science/Editorial Board, John E. Coligan. [et al.], Chapter 18 2011 (Unit18 13)
34. I. Berezniuk, J. Sironi, M.B. Callaway, L.M. Castro, I.Y. Hirata, E.S. Ferro, and L.D. Fricker CCP1/Nna1 functions in protein turnover in mouse brain: implications for cell death in Purkinje cell degeneration mice FASEB J. 24 2010 1813 1823
35. J.S. Gelman, J. Sironi, L.M. Castro, E.S. Ferro, and L.D. Fricker Hemopressins and other hemoglobin-derived peptides in mouse brain: comparison between brain, blood, and heart peptidome and regulation in Cpefat/fat mice J. Neurochem. 113 2010 871 880
36. D.J. Morgan, S. Wei, I. Gomes, T. Czyzyk, N. Mzhavia, H. Pan, L.A. Devi, L.D. Fricker, and J.E. Pintar The propeptide precursor proSAAS is involved in fetal neuropeptide processing and body weight regulation J. Neurochem. 113 2010 1275 1284
37. J.H. Wardman, X. Zhang, S. Gagnon, L.M. Castro, X. Zhu, D.F. Steiner, R. Day, and L.D. Fricker Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics J. Neurochem. 114 2010 215 225
38. X. Zhang, H. Pan, B. Peng, D.F. Steiner, J.E. Pintar, and L.D. Fricker Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis J. Neurochem. 112 2010 1168 1179
39. J.C. Price, S. Guan, A. Burlingame, S.B. Prusiner, and S. Ghaemmaghami Analysis of proteome dynamics in the mouse brain Proc. Natl. Acad. Sci. U. S. A. 107 2010 14508 14513
40. G. Baggerman, A. Cerstiaens, A. DeLoof, and L. Schoofs Peptidomics of the larval Drosophila melanogaster central nervous system J. Biol. Chem. 277 2002 40368 40374 (Pubitemid 35215610)
41. P. Schulz-Knappe, H.D. Zucht, G. Heine, M. Jurgens, R. Hess, and M. Schrader Peptidomics: the comprehensive analysis of peptides in complex biological mixtures Comb. Chem. High Throughput Screen. 4 2001 207 217 (Pubitemid 32410542)
42. S.S. Rubakhin, J.D. Churchill, W.T. Greenough, and J.V. Sweedler Profiling signaling peptides in single mammalian cells using mass spectrometry Anal. Chem. 78 2006 7267 7272 (Pubitemid 44607573)
43. E. Reits, J. Neijssen, C. Herberts, W. Benckhuijsen, L. Janssen, J.W. Drijfhout, and J. Neefjes A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation Immunity 20 2004 495 506 (Pubitemid 38482126)
44. J.S. Gelman, J. Sironi, I. Berezniuk, S. Dasgupta, L.M. Castro, F.C. Gozzo, E.S. Ferro, and L.D. Fricker Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomib PLoS One 8 2013 e53263
45. S.P. Annangudi, A.E. Luszpak, S.H. Kim, S. Ren, N.G. Hatcher, I.J. Weiler, K.T. Thornley, B.M. Kile, R.M. Wightman, W.T. Greenough, and J.V. Sweedler Neuropeptide release in impaired in a mouse model of Fragile X Mental Retardation Syndrome ACS Chem. Neurosci. 1 2010 306 314
46. B. Scholz, K. Skold, K. Kultima, C. Fernandez, S. Waldemarson, M.M. Savitski, M. Soderquist, M. Boren, R. Stella, P. Andren, R. Zubarev, and P. James Impact of temperature dependent sampling procedures in proteomics and peptidomics - a characterization of the liver and pancreas post mortem degradome Mol. Cell Proteomics 10 2011 (M900229MCP900200)
47. J.A. Dowell, W.V. Heyden, and L. Li Rat neuropeptidomics by LC-MS/MS and MALDI-FTMS: enhanced dissection and extraction techniques coupled with 2D RP-RP HPLC J. Proteome Res. 5 2006 3368 3375 (Pubitemid 44904328)
48. S.L. Mehta, N. Manhas, and R. Raghubir Molecular targets in cerebral ischemia for developing novel therapeutics Brain Res. Rev. 54 2007 34 66 (Pubitemid 46498164)
49. L.D. Fricker, R.J. Rigual, E.J.J. Diliberto, and O.H. Viveros Reflex splanchnic nerve stimulation increases levels of carboxypeptidase E mRNA and enzymatic activity in the rat adrenal medulla J. Neurochem. 55 1990 461 467
50. F. Richter, B.H. Meurers, C. Zhu, V.P. Medvedeva, and M.F. Chesselet Neurons express hemoglobin alpha and beta chains in rat and human brains J. Comp. Neurol. 51 2009 538 547
51. M. Biagioli, M. Pinto, D. Cesselli, M. Zaninello, D. Lazarevic, P. Roncaglia, R. Simone, C. Vlachouli, C. Plessy, N. Bertin, A. Beltrami, K. Kobayashi, V. Gallo, C. Santoro, I. Ferrer, S. Rivella, C.A. Beltrami, P. Carninci, E. Raviola, and S. Gustincich Unexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells Proc. Natl. Acad. Sci. U. S. A. 106 2009 15454 15459
52. H. Dassen, R. Kamps, C. Punyadeera, F. Dijcks, A. de Goeij, A. Ederveen, G. Dunselman, and P. Groothuis Haemoglobin expression in human endometrium Hum. Reprod. 23 2008 635 641 (Pubitemid 351651226)
53. F.C. Mansergh, S.M. Hunter, J.C. Geatrell, M. Jarrin, K. Powell, M.J. Evans, and M.A. Wride Developmentally regulated expression of hemoglobin subunits in avascular tissues Int. J. Dev. Biol. 52 2008 873 886
54. H. Nishi, R. Inagi, H. Kato, M. Tanemoto, I. Kojima, D. Son, T. Fujita, and M. Nangaku Hemoglobin is expressed by mesangial cells and reduces oxidant stress J. Am. Soc. Nephrol. 19 2008 1500 1508
55. D.A. Newton, K.M. Rao, R.A. Dluhy, and J.E. Baatz Hemoglobin is expressed by alveolar epithelial cells J. Biol. Chem. 281 2006 5668 5676 (Pubitemid 43847664)
56. L. Liu, M. Zeng, and J.S. Stamler Hemoglobin induction in mouse macrophages Proc. Natl. Acad. Sci. U. S. A. 96 1999 6643 6647 (Pubitemid 29274936)
57. A.C. Howlett, C.S. Breivogel, S.R. Childers, S.A. Deadwyler, R.E. Hampson, and L.J. Porrino Cannabinoid physiology and pharmacology: 30 years of progress Neuropharmacology 47 Suppl. 1 2004 345 358 (Pubitemid 39298276)
58. D. Boehning, and S.H. Snyder Novel neural modulators Annu. Rev. Neurosci. 26 2003 105 131 (Pubitemid 37064930)
59. M.H. Stridh, M. Tranberg, S.G. Weber, F. Blomstrand, and M. Sandberg Stimulated efflux of amino acids and glutathione from cultured hippocampal slices by omission of extracellular calcium: likely involvement of connexin hemichannels J. Biol. Chem. 283 2008 10347 10356
60. O.J. Holt, F. Gallo, and G.M. Griffiths Regulating secretory lysosomes J. Biochem. 140 2006 7 12 (Pubitemid 44433540)
61. E.J. Blott, and G.M. Griffiths Secretory lysosomes Nat. Rev. Mol. Cell Biol. 3 2002 122 131
62. E.S. Ferro, S. Hyslop, and A.C. Camargo Intracellullar peptides as putative natural regulators of protein interactions J. Neurochem. 91 2004 769 777 (Pubitemid 39507353)
63. M. Rubinstein, and M.Y. Niv Peptidic modulators of protein-protein interactions: progress and challenges in computational design Biopolymers 91 2009 505 513
64. E.N. Churchill, N. Qvit, and D. Mochly-Rosen Rationally designed peptide regulators of protein kinase C Trends Endocrinol. Metab. 20 2009 25 33
65. M.R. Arkin, and A. Whitty The road less traveled: modulating signal transduction enzymes by inhibiting their protein-protein interactions Curr. Opin. Chem. Biol. 13 2009 284 290
66. C.M. Haynes, Y. Yang, S.P. Blais, T.A. Neubert, and D. Ron The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans Mol. Cell 37 2010 529 540
67. T. Kondo, S. Plaza, J. Zanet, E. Benrabah, P. Valenti, Y. Hashimoto, S. Kobayashi, F. Payre, and Y. Kageyama Small peptides switch the transcriptional activity of Shavenbaby during Drosophila embryogenesis Science 329 2010 336 339