Improved efficiency of multi-criteria IMPT treatment planning using iterative resampling of randomly placed pencil beams

Physics in Medicine and Biology

Volumn 58, Issue 19, 2013, Pages 6969-6983

  Van De Water, S ^a   Kraan, A C ^a   Breedveld, S ^a   Schillemans, W ^a   Teguh, D N ^a   Kooy, H M ^b   Madden, T M ^b   Heijmen, B J M ^a   Hoogeman, M S ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOTROPIC GRID; HEAD-AND-NECK CANCER; INTENSITY-MODULATED PROTON THERAPIES; MULTICRITERIA OPTIMIZATION; RANDOM SELECTION; TREATMENT PLANNING; TREATMENT PLANNING SYSTEMS; WEIGHT OPTIMIZATION;

ANISOTROPY; PROTONS; SIMULATED ANNEALING;

PATIENT TREATMENT;

ANISOTROPY; ARTICLE; COMPUTER ASSISTED RADIOTHERAPY; HUMAN; INTENSITY MODULATED RADIATION THERAPY; METHODOLOGY; ORGANS AT RISK; OROPHARYNX TUMOR; PROTON THERAPY; RADIATION EXPOSURE; OROPHARYNGEAL NEOPLASMS; PROCEDURES; RADIATION RESPONSE;

ANISOTROPY; HUMANS; ORGANS AT RISK; OROPHARYNGEAL NEOPLASMS; PROTON THERAPY; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, INTENSITY-MODULATED;

EID: 84884644780     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/58/19/6969     Document Type: Article

References (18)

1. Breedveld S, Storchi P R M and Heijmen B J M 2009 The equivalence of multi-criteria methods for radiotherapy plan optimization Phys. Med. Biol. 54 7199-209
2. Breedveld S, Storchi P R M, Voet P W J and Heijmen B J M 2012 iCycle: integrated, multicriterial beam angle, and profile optimization for generation of coplanar and noncoplanar IMRT plans Med. Phys. 39 951-63
3. Hillbrand M and Georg D 2010 Assessing a set of optimal user interface parameters for intensity-modulated proton therapy planning J. Appl. Clin. Med. Phys. 11 93-104
4. Kang J H, Wilkens J J and Oelfke U 2008 Non-uniform depth scanning for proton therapy systems employing active energy variation Phys. Med. Biol. 53 N149-55 (Pubitemid 351570922)
5. Kooy H M et al 2010 A case study in proton pencil-beam scanning delivery Int. J. Radiat. Oncol. Biol. Phys. 76 624-30
6. Lomax A 1999 Intensity modulation methods for proton radiotherapy Phys. Med. Biol. 44 185-205 (Pubitemid 29062235)
7. Pedroni E et al 2004 The PSI gantry 2: a second generation proton scanning gantry Z. Med. Phys. 14 25-34 (Pubitemid 38435678)
8. Pflugfelder D, Wilkens J J and Oelfke U 2008 Worst case optimization: a method to account for uncertainties in the optimization of intensity modulated proton therapy Phys. Med. Biol. 53 1689-700 (Pubitemid 351423005)
9. Schippers J M and Lomax A J 2011 Emerging technologies in proton therapy Acta. Oncol. 50 838-50
10. Schweikard A, Schlaefer A and Adler J R 2006 Resampling: an optimization method for inverse planning in robotic radiosurgery Med. Phys. 33 4005-11 (Pubitemid 44673092)
11. Unkelbach J, Bortfeld T, Martin B C and Soukup M 2009 Reducing the sensitivity of IMPT treatment plans to setup errors and range uncertainties via probabilistic treatment planning Med. Phys. 36 149-63
12. Van de Water S, Hoogeman M S, Breedveld S and Heijmen B J M 2011a Shortening treatment time in robotic radiosurgery using a novel node reduction technique Med. Phys. 38 1397-405
13. Van de Water T A, Lomax A J, Bijl H P, de Jong M E, Schilstra C, Hug E B and Langendijk J A 2011b Potential benefits of scanned intensity-modulated proton therapy versus advanced photon therapy with regard to sparing of the salivary glands in oropharyngeal cancer Int. J. Radiat. Oncol. Biol. Phys. 79 1216-24
14. Van de Water T A, Lomax A J, Bijl H P, Schilstra C, Hug E B and Langendijk J A 2012 Using a reduced spot size for intensity-modulated proton therapy potentially improves salivary gland-sparing in oropharyngeal cancer Int. J. Radiat. Oncol. Biol. Phys. 82 e313-9
15. Voet P W J, Dirkx M L P, Breedveld S, Fransen D, Levendag P C and Heijmen B J M 2013 Toward fully automated multicriterial plan generation: a prospective clinical study Int. J. Radiat. Oncol. Biol. Phys. 85 866-72
16. Widesott L, Lomax A J and Schwarz M 2012 Is there a single spot size and grid for intensity modulated proton therapy? Simulation of head and neck, prostate and mesothelioma cases Med. Phys. 39 1298-308
17. Widesott L, Pierelli A, Fiorino C, Dell'Oca I, Broggi S, Cattaneo G M, Di Muzio N, Fazio F, Calandrino R and Schwarz M 2008 Intensity-modulated proton therapy versus helical tomotherapy in nasopharynx cancer: planning comparison and NTCP evaluation Int. J. Radiat. Oncol. Biol. Phys. 72 589-96
18. Zenklusen S M, Pedroni E and Meer D 2010 A study on repainting strategies for treating moderately moving targets with proton pencil beam scanning at the new gantry 2 at PSI Phys. Med. Biol. 55 5103-21